Standard name
Human Ortholog
Description Protein component of the small (40S) ribosomal subunit; required for assembly and maturation of pre-40 S particles; homologous to mammalian ribosomal protein S19, no bacterial homolog; mutations in human RPS19 are associated with Diamond Blackfan anemia; RPS19A has a paralog, RPS19B, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0.05 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.05 0 0 0.05 0.05 – 0 0.05 0.06 0.12 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.99 0.95 1.0 0.9 0.88 0.81 – 0.79 0.72 0.81 0.75 0.97 0.97 0.99 0.98 0.97 0.93 0.98 0.92 0.93 0.93 0.9 0.89
Endoplasmic Reticulum 0 0 0 0 0 0.08 0.14 – 0.11 0.15 0.06 0.08 0 0 0 0.05 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 – 0.09 0.06 0.12 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.05 0 0 – 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 1 5 – 7 7 6 12 0 0 0 0 0 0 0 0 0 0 0 0
Bud 1 0 0 0 0 0 0 – 0 0 1 0 0 0 0 0 2 0 1 1 1 1 7 4
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 3 6 4 0 7 9 – 7 8 8 19 5 7 4 0 3 0 0 0 2 0 1 0
Cytoplasm 195 210 123 102 84 122 145 – 134 115 104 119 225 306 342 177 138 98 185 188 121 182 294 233
Endoplasmic Reticulum 1 2 4 0 2 11 25 – 18 24 8 12 7 5 2 9 5 5 0 2 3 1 9 10
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 1 – 3 4 3 10 0 0 0 3 0 1 0 0 0 0 0 0
Mitochondria 0 0 0 0 3 1 1 – 15 10 15 13 0 0 0 2 1 0 0 1 0 0 1 0
Nucleus 0 1 0 0 0 0 1 – 0 0 2 0 0 1 0 0 0 0 0 5 0 3 0 0
Nuclear Periphery 0 0 0 0 1 0 0 – 0 1 0 1 0 0 0 0 0 0 0 0 0 1 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 1 0 0 0 5 1 2 – 0 2 3 3 1 1 3 1 1 5 1 3 0 2 4 7
Unique Cell Count 196 213 129 102 93 138 179 170 159 128 158 233 315 347 180 142 105 190 205 131 195 326 262
Labelled Cell Count 198 216 133 106 95 143 189 184 171 150 189 238 320 351 192 150 109 190 205 131 195 326 262


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 59.1 52.8 55.1 50.5 27.8 31.6 28.3 – 24.8 24.2 23.2 22.4 52.2 51.5 47.4 65.2 84.8 76.0 56.2 60.1 55.9
Std Deviation (1e-4) 12.2 13.7 11.6 9.1 10.6 7.7 7.0 – 6.1 6.5 7.0 6.8 14.7 10.9 13.1 20.3 24.0 27.1 16.9 16.8 18.7
Intensity Change (Log2) – – – -0.13 -0.99 -0.8 -0.96 – -1.16 -1.19 -1.25 -1.3 -0.08 -0.1 -0.22 0.24 0.62 0.46 0.03 0.12 0.02

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP700050100WT3HU80HU120HU160050100WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3050100WT1AF100AF140AF180050100
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 3.2 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0.2 0.2 – -0.2 0.1 0.6 2.2 0 0 0 0 0 0
Cytoplasm 2.2 -1.5 -2.1 -3.7 – -4.1 -5.1 -3.5 -4.6 0.6 0.9 2.1 1.5 0.8 -0.7
Endoplasmic Reticulum 0 0 1.7 3.2 – 2.5 3.4 1.2 1.7 0 0 0 0.8 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 3.5 0 4.0 3.3 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 61.2611 76.9483 69.9087 71.3644 64.9003 70.4138 71.7325 100.6957 90.5123 91.8757 80.4538 89.7652 62.3694 80.1286 75.8274 62.846 78.3275 66.2988
Actin 0.0146 0.0003 0.0109 0.0001 0.051 0.0031 0.0054 0.0002 0.0057 0.0001 0.0009 0.0006 0.0153 0.0003 0.0183 0.0109 0.0008 0.0092
Bud 0.0013 0.0004 0.0005 0.0013 0.0007 0.0036 0.0019 0.0004 0.0017 0.0007 0.0031 0.0005 0.0021 0.0002 0.0005 0.003 0.0002 0.0034
Bud Neck 0.0014 0.0003 0.0014 0.0006 0.0035 0.0024 0.0008 0.0007 0.0011 0.0009 0.0011 0.0037 0.0008 0.0002 0.0005 0.0009 0.0005 0.0022
Bud Periphery 0.0016 0.0008 0.0004 0.0007 0.0005 0.0052 0.0032 0.0005 0.0022 0.0005 0.0041 0.0003 0.0044 0.0001 0.0004 0.0011 0.0001 0.0055
Bud Site 0.0036 0.0001 0.0009 0.0002 0.0002 0.0011 0.0011 0.0005 0.0006 0.0001 0.0012 0.0001 0.0052 0.0002 0.0008 0.0084 0 0.016
Cell Periphery 0.0076 0.0047 0.0033 0.0037 0.0023 0.0056 0.0119 0.0106 0.007 0.0117 0.0072 0.003 0.0014 0.0007 0.0025 0.0025 0.0028 0.0008
Cytoplasm 0.7531 0.9575 0.8506 0.7619 0.8076 0.8029 0.7608 0.9235 0.8652 0.8184 0.7999 0.8753 0.7907 0.977 0.9166 0.7707 0.9092 0.879
Cytoplasmic Foci 0.0051 0.001 0.0056 0.0052 0.0038 0.0049 0.0082 0.0005 0.0051 0.001 0.0136 0.0052 0.0522 0.0007 0.002 0.0175 0.0062 0.0123
Eisosomes 0.0006 0 0.0001 0 0.0002 0.0002 0.0005 0 0.0002 0 0.0004 0 0.0001 0 0.0001 0.0001 0 0.0001
Endoplasmic Reticulum 0.049 0.0174 0.0428 0.0196 0.0054 0.0709 0.0437 0.0177 0.0214 0.0062 0.0113 0.0462 0.0368 0.0123 0.0196 0.0043 0.0046 0.0164
Endosome 0.0097 0.002 0.0077 0.0345 0.0114 0.0208 0.0088 0.0012 0.0036 0.0039 0.0057 0.0043 0.0115 0.0008 0.0034 0.059 0.0376 0.0087
Golgi 0.0022 0.0004 0.0012 0.0011 0.0019 0.0028 0.0012 0.0001 0.0006 0.0002 0.0006 0.0005 0.0047 0.0001 0.0008 0.0228 0.0012 0.0027
Lipid Particles 0.0033 0.0004 0.0016 0.0022 0.0008 0.0023 0.0032 0.0008 0.0025 0.001 0.0051 0.001 0.0035 0.0001 0.0007 0.0132 0.0006 0.0029
Mitochondria 0.0084 0.0004 0.0015 0.0007 0.0016 0.004 0.0073 0.0011 0.0059 0.0072 0.0181 0.0006 0.0038 0.0001 0.0008 0.0065 0.0003 0.0049
None 0.0042 0.0001 0.005 0.0011 0.0014 0.0025 0.0074 0.0002 0.0049 0.0009 0.0146 0.0037 0.005 0.0001 0.0079 0.0011 0.0002 0.0112
Nuclear Periphery 0.0302 0.0019 0.0075 0.0167 0.0178 0.0068 0.0242 0.0028 0.0075 0.011 0.0099 0.0097 0.017 0.001 0.0046 0.0081 0.0038 0.0062
Nucleolus 0.0036 0 0.004 0.0002 0.0017 0.0022 0.0093 0.0004 0.0026 0.0035 0.0097 0.0005 0.0004 0 0.0002 0.0003 0 0.0016
Nucleus 0.0109 0.001 0.005 0.0034 0.0065 0.0044 0.0119 0.0028 0.0077 0.0061 0.013 0.0074 0.0083 0.0008 0.0018 0.0038 0.0013 0.0048
Peroxisomes 0.0107 0 0.0059 0.0001 0.0001 0.001 0.0004 0 0.0003 0.0001 0.0009 0.0001 0.0025 0 0.0004 0.0051 0 0.0006
Punctate Nuclear 0.0012 0 0.0012 0.0004 0.0015 0.0024 0.0015 0 0.0009 0 0.0043 0.0003 0.0077 0 0.0003 0.0015 0.0001 0.0035
Vacuole 0.0586 0.0098 0.0366 0.1162 0.0559 0.0341 0.0727 0.0323 0.0448 0.0995 0.0606 0.0323 0.0182 0.0048 0.0147 0.0453 0.0271 0.0055
Vacuole Periphery 0.0191 0.0013 0.0064 0.0302 0.0241 0.0168 0.0147 0.0037 0.0085 0.027 0.0148 0.0047 0.0084 0.0004 0.0032 0.0136 0.0034 0.0025

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1279.6955 1448.9526 1733.0843 1406.8647 1530.9194 1300.5359 1189.9106 1133.483 1307.3258 1180.3971
Translational Efficiency 1.5448 1.4956 1.3598 1.5058 1.6422 1.5684 1.6209 1.6764 1.539 1.8325

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
46 1150 2205 1775 2275 1980 1895 166 2321 3130 4100 1941

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 2183.38 3528.43 5153.82 4201.91 2966.78 3468.18 4187.09 4949.63 2951.25 3490.32 4707.00 4265.86
Standard Deviation 718.60 938.59 924.97 1150.49 540.80 704.63 1110.02 1075.06 555.72 799.12 1123.36 1163.18
Intensity Change Log 2 — 0.692463 1.239079 0.944482 — 0.225281 0.497050 0.738423 — 0.442039 0.858946 0.829397

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001775 0.000098 0.000042 0.000149 0.000031 0.000073 0.000169 0.000122 0.000066 0.000082 0.000101 0.000146
Bud Neck 0.001517 0.000662 0.000187 0.001399 0.000144 0.000273 0.001720 0.001346 0.000171 0.000416 0.000896 0.001394
Bud Site 0.038493 0.004518 0.003231 0.007222 0.002403 0.003796 0.005175 0.006788 0.003119 0.004061 0.004130 0.007184
Cell Periphery 0.054877 0.008620 0.010105 0.003452 0.002139 0.003729 0.006419 0.040324 0.003184 0.005526 0.008402 0.006605
Cytoplasm 0.110972 0.745778 0.843950 0.845615 0.742042 0.853673 0.738904 0.676708 0.729535 0.814031 0.795398 0.831170
Cytoplasmic Foci 0.042284 0.013511 0.006241 0.005540 0.021774 0.014791 0.005580 0.011335 0.022181 0.014320 0.005936 0.006035
Eisosomes 0.000037 0.000001 0.000001 0.000002 0.000001 0.000001 0.000002 0.000003 0.000001 0.000001 0.000002 0.000002
Endoplasmic Reticulum 0.017022 0.001078 0.001050 0.000159 0.001912 0.001125 0.000443 0.000185 0.002212 0.001107 0.000769 0.000161
Endosome 0.013210 0.001258 0.000400 0.001241 0.001198 0.001094 0.001350 0.000570 0.001437 0.001154 0.000839 0.001184
Golgi 0.360038 0.077546 0.017027 0.010397 0.070495 0.047891 0.014107 0.032400 0.076234 0.058787 0.015677 0.012279
Lipid Particles 0.037429 0.009949 0.006741 0.005028 0.002586 0.005688 0.007830 0.027969 0.003277 0.007254 0.007244 0.006990
Mitochondria 0.022311 0.000160 0.000411 0.000541 0.000264 0.000286 0.000293 0.000060 0.000701 0.000240 0.000356 0.000500
Mitotic Spindle 0.002196 0.001578 0.000355 0.003511 0.001287 0.001044 0.001568 0.001045 0.001305 0.001240 0.000915 0.003300
None 0.003394 0.003482 0.000836 0.002404 0.001247 0.002608 0.006569 0.001814 0.001289 0.002929 0.003486 0.002354
Nuclear Periphery 0.000712 0.000448 0.000235 0.000220 0.000277 0.000110 0.000375 0.000639 0.000285 0.000234 0.000300 0.000256
Nuclear Periphery Foci 0.019643 0.015448 0.004767 0.005370 0.010264 0.006166 0.006386 0.012029 0.010450 0.009577 0.005515 0.005940
Nucleolus 0.006083 0.000244 0.000055 0.000218 0.000033 0.000063 0.000246 0.000081 0.000153 0.000129 0.000143 0.000207
Nucleus 0.056395 0.009026 0.003198 0.038736 0.001938 0.003078 0.038299 0.027648 0.003017 0.005263 0.019422 0.037787
Peroxisomes 0.001385 0.000020 0.000075 0.000044 0.000013 0.000033 0.000091 0.000038 0.000040 0.000028 0.000082 0.000043
Vacuole 0.085443 0.048548 0.064432 0.056970 0.028103 0.021015 0.144466 0.138126 0.029239 0.031131 0.101423 0.063911
Vacuole Periphery 0.124785 0.058025 0.036660 0.011782 0.111849 0.033465 0.020011 0.020770 0.112106 0.042489 0.028965 0.012551

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.93 2.00 1.86 -1.94 -4.08 -2.55 -6.16 -3.98 -2.08 0.95 -1.04 -2.18 -3.03 -2.53 -1.72
Bud Neck 2.23 3.35 -0.75 -6.91 -10.37 -2.45 -12.44 -2.87 -2.65 0.86 -4.95 -12.01 -10.86 -9.02 -3.14
Bud Site 1.76 1.84 1.62 -1.94 -3.52 -2.76 -4.98 -2.64 -1.79 -0.74 -1.77 -2.29 -3.68 -2.80 -2.64
Cell Periphery 2.63 2.54 2.97 6.41 9.69 -5.10 -7.15 -6.20 -5.92 -5.58 -4.62 -8.74 -3.84 -0.62 2.72
Cytoplasm -18.62 -22.06 -21.04 -6.13 4.28 -13.71 4.01 3.09 7.74 1.57 -10.46 -6.33 -8.00 2.22 -2.67
Cytoplasmic Foci 3.85 4.90 4.89 6.32 -0.11 5.08 13.13 5.46 1.86 -3.36 6.22 14.38 13.24 9.50 -0.81
Eisosomes 3.77 3.81 3.69 -1.54 -2.70 -2.28 -8.31 -5.63 -4.27 -1.21 0.33 -1.83 -2.25 -2.68 -1.33
Endoplasmic Reticulum 4.11 4.12 4.35 7.87 8.63 2.83 5.95 6.97 7.19 4.45 4.05 5.51 7.99 10.26 9.85
Endosome 5.81 6.24 5.82 0.47 -2.08 0.63 -1.00 4.66 4.00 3.36 2.10 3.51 1.16 0.36 -0.51
Golgi 5.99 7.36 7.54 18.08 7.82 6.67 22.09 8.92 3.97 -4.87 5.08 21.83 23.14 22.68 4.77
Lipid Particles 2.75 3.08 3.25 4.25 2.13 -4.24 -8.28 -6.55 -5.66 -5.15 -6.23 -8.16 -5.74 0.18 0.18
Mitochondria 1.07 1.06 1.05 -1.72 -0.46 -0.38 -1.03 6.85 3.77 5.51 1.11 0.80 0.51 -1.22 -0.54
Mitotic Spindle 0.96 3.04 -1.91 -2.97 -4.86 1.15 -1.82 1.39 0.25 2.27 0.21 0.38 -3.66 -3.63 -3.64
None 0.04 1.39 0.48 1.28 -7.92 -2.35 -4.18 -2.59 1.31 3.59 -3.74 -3.60 -5.91 0.79 0.99
Nuclear Periphery 1.09 1.57 1.44 1.99 -2.20 5.73 -4.35 -4.49 -6.92 -2.23 1.37 -1.59 -1.24 -2.93 0.38
Nuclear Periphery Foci 0.91 1.98 1.94 9.26 -0.64 5.79 4.91 -1.01 -3.65 -3.32 1.22 7.20 6.51 6.19 -0.25
Nucleolus 1.58 1.62 1.58 -0.11 -6.37 -1.38 -9.05 -6.32 -0.97 6.90 0.45 0.10 -0.75 -2.37 -2.47
Nucleus 2.12 2.34 -0.17 -17.74 -20.64 -2.98 -20.10 -4.98 -4.80 1.98 -3.01 -16.66 -21.20 -20.52 -12.51
Peroxisomes 1.60 1.54 1.57 -3.39 3.40 -3.31 -1.62 -1.67 -0.29 0.99 0.73 -1.29 -0.01 -2.04 1.69
Vacuole 1.69 0.95 0.88 -3.90 -0.32 3.80 -24.54 -7.34 -7.79 1.56 -1.11 -24.63 -12.33 -11.65 8.62
Vacuole Periphery 2.47 3.33 4.41 14.23 14.64 19.41 24.75 18.03 3.44 -0.55 17.58 22.49 27.49 17.20 12.99
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein component of the small (40S) ribosomal subunit; required for assembly and maturation of pre-40 S particles; homologous to mammalian ribosomal protein S19, no bacterial homolog; mutations in human RPS19 are associated with Diamond Blackfan anemia; RPS19A has a paralog, RPS19B, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-2

Rps19a

Rps19a


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rps19a-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available