Standard name
Human Ortholog
Description Vacuolar membrane protein of unknown function; involved in vacuolar protein sorting; also detected in the mitochondria
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.09 0.09 0.08 0.08 – 0.09 0.11 0.1 0.14 0 0 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.21 0.13 0.38 0.45 0.22 0.14 0.16 – 0.14 0.14 0.1 0.09 0.43 0.41 0.36 0.06 0 0 0.28 0.3 0.39 0.52 0.56 0.51
Golgi 0 0 0 0.07 0.12 0.08 0.31 – 0.2 0.25 0.19 0.22 0.05 0.06 0.08 0.11 0.19 0.29 0.05 0 0 0.05 0.05 0.08
Mitochondria 0.19 0.14 0 0.08 0.07 0.48 0.09 – 0.35 0.19 0.31 0.27 0.12 0.09 0 0 0 0.05 0 0 0 0 0 0
Nucleus 0 0 0 0 0.05 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0.05 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.06 0.06 0 0 0 0.07 0 0 0
Nucleolus 0.16 0.12 0.21 0.13 0.18 0.28 0.2 – 0.23 0.21 0.22 0.17 0.2 0.24 0.19 0.11 0.12 0.08 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0.1 0.08 0.14 0 0.09 – 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.71 0.75 0.64 0.47 0.46 0.21 0.37 – 0.26 0.34 0.31 0.35 0.61 0.61 0.69 0.87 0.92 0.88 0.53 0.57 0.41 0.3 0.28 0.31
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 2 0 3 7 – 5 10 7 9 1 0 0 1 1 1 0 1 0 0 1 2
Bud 1 0 0 0 0 4 5 – 3 3 6 1 0 0 0 0 0 0 0 4 1 1 0 1
Bud Neck 0 0 0 0 0 0 0 – 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 1 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 1 0 4 – 5 6 3 7 0 0 0 0 1 0 0 0 0 0 0 0
Cytoplasm 6 13 11 12 17 17 29 – 24 26 20 22 1 5 6 2 4 1 0 1 1 0 0 0
Endoplasmic Reticulum 1 1 0 0 0 0 1 – 2 2 3 2 0 0 0 1 2 1 0 0 2 0 0 1
Endosome 39 45 93 61 41 31 56 – 38 35 20 14 100 112 107 3 2 3 58 115 102 81 139 154
Golgi 4 5 4 10 23 18 109 – 55 61 38 36 12 17 23 5 22 23 10 4 6 7 12 25
Mitochondria 35 50 7 11 13 108 32 – 99 46 62 43 27 23 10 1 4 4 5 8 8 4 7 6
Nucleus 6 11 8 1 10 4 2 – 4 6 2 5 0 0 0 0 0 2 4 7 2 0 0 0
Nuclear Periphery 9 12 5 2 1 1 4 – 2 2 1 3 6 4 6 3 7 2 7 8 17 3 8 8
Nucleolus 30 41 52 18 34 62 69 – 64 52 44 28 47 65 56 5 13 6 3 5 4 1 2 2
Peroxisomes 1 0 0 0 5 2 6 – 1 2 1 0 0 0 0 0 0 0 0 0 1 0 0 1
SpindlePole 5 12 25 11 26 8 31 – 5 7 6 2 4 13 11 2 1 0 3 6 5 3 1 3
Vac/Vac Membrane 133 267 156 64 88 46 128 – 73 84 62 56 141 165 205 41 104 69 109 222 107 46 70 94
Unique Cell Count 187 355 245 135 190 223 349 279 246 197 162 230 270 295 47 113 78 207 387 263 156 248 302
Labelled Cell Count 270 458 361 192 259 304 483 381 342 275 229 339 404 424 64 161 112 207 387 263 156 248 302


Vacuole Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.5 9.5 9.5 10.0 14.9 9.9 14.5 – 13.6 13.8 12.9 13.7 12.0 13.8 14.8 21.4 25.2 24.7 9.0 11.0 12.9
Std Deviation (1e-4) 2.8 2.5 1.9 2.6 6.6 3.3 3.3 – 3.9 4.1 4.5 5.1 2.8 3.2 3.7 7.0 7.6 5.9 2.6 3.3 3.8
Intensity Change (Log2) – – – 0.07 0.66 0.06 0.61 – 0.53 0.54 0.44 0.53 0.34 0.55 0.64 1.18 1.41 1.38 -0.08 0.21 0.44

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000102030WT3HU80HU120HU1600102030WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30102030WT1AF100AF140AF1800102030
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.7 1.9 1.4 1.8 – 1.9 2.6 2.3 3.3 -2.8 -1.7 -1.6 0 0 0
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 1.4 -3.7 -5.9 -6.1 – -6.4 -6.0 -6.7 -6.6 1.2 0.8 -0.4 -4.2 -7.2 -5.7
Golgi 0 4.5 3.3 9.0 – 6.5 7.6 6.3 6.8 2.2 2.7 3.3 0 6.0 7.7
Mitochondria 2.3 2.0 11.4 3.1 – 9.3 5.7 8.2 7.1 3.8 2.7 0.4 0 0 0
Nucleus 0 1.0 -1.0 0 – -1.4 -0.6 0 -0.1 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0.4 0 0 0 0 0
Nucleolus -1.9 -0.9 1.7 -0.4 – 0.5 0 0.3 -1.0 -0.2 0.8 -0.6 -1.7 -2.2 -2.7
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole -0.7 1.1 -2.8 -0.5 – -4.1 -3.3 -2.9 -3.6 -3.9 -2.3 -3.0 0 -3.2 -2.9
Vacuole -3.1 -3.6 -9.4 -6.5 – -8.6 -6.5 -6.7 -5.8 -0.5 -0.6 1.4 3.2 5.6 4.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.6786 5.5707 5.1414 4.9895 4.4129 5.424 7.0119 8.3059 8.3091 7.2961 7.4894 7.9155 9.4777 11.1915 9.6862 9.7637 9.7937 10.5641
Actin 0.0003 0 0.0038 0.0116 0.0323 0.0007 0.0003 0.0001 0.0001 0 0 0.0001 0.0387 0 0.0076 0.0002 0.0012 0
Bud 0.0001 0.0001 0.0002 0.0002 0.0005 0.0001 0.0001 0.0001 0.0002 0.0003 0 0.0001 0.0005 0 0.0002 0 0.0001 0
Bud Neck 0.0002 0.0002 0.0003 0.0014 0.0009 0.0002 0.0002 0.0003 0.0003 0.0001 0.0001 0.0002 0.0016 0.0001 0.0004 0.0001 0.0002 0.0001
Bud Periphery 0.0003 0.0001 0.0003 0.0002 0.0007 0.0001 0.0002 0.0001 0.0002 0.0004 0.0001 0.0002 0.0008 0.0001 0.0003 0 0.0002 0.0001
Bud Site 0.0002 0.0003 0.0003 0.001 0.0014 0.0001 0.0003 0.0003 0.0002 0.0003 0.0001 0.0001 0.0027 0.0001 0.0007 0.0001 0.0002 0.0001
Cell Periphery 0.0005 0.0004 0.0006 0.0002 0.0001 0.0002 0.0002 0.0005 0.0003 0.0002 0.0002 0.0002 0.0004 0.0004 0.0004 0.0001 0.0001 0.0002
Cytoplasm 0.0043 0.0023 0.0019 0.001 0.0012 0.0015 0.001 0.002 0.0013 0.0007 0.0007 0.0007 0.0008 0.0009 0.0007 0.0004 0.0021 0.0004
Cytoplasmic Foci 0.0178 0.0355 0.0284 0.0352 0.0246 0.0189 0.0284 0.0422 0.0304 0.0178 0.0358 0.0219 0.0256 0.0327 0.0206 0.0363 0.0417 0.019
Eisosomes 0 0 0 0 0.0001 0 0 0 0 0 0 0 0.0003 0 0.0001 0 0 0
Endoplasmic Reticulum 0.0021 0.0006 0.0012 0.0003 0.0013 0.0013 0.0006 0.0006 0.0011 0.0003 0.0006 0.0006 0.0023 0.0004 0.001 0.0004 0.0025 0.0005
Endosome 0.4047 0.3793 0.3574 0.3704 0.4533 0.3696 0.4846 0.3832 0.4787 0.5283 0.4105 0.4473 0.3397 0.3507 0.3902 0.3457 0.4683 0.3493
Golgi 0.0353 0.0325 0.0463 0.0498 0.0599 0.0445 0.0412 0.0325 0.0675 0.0359 0.0519 0.0676 0.0437 0.0385 0.0599 0.0317 0.0379 0.0423
Lipid Particles 0.0514 0.0551 0.066 0.036 0.0225 0.0668 0.0755 0.0709 0.07 0.0223 0.0596 0.0721 0.1534 0.0602 0.0814 0.0286 0.0267 0.0959
Mitochondria 0.0139 0.0025 0.0122 0.0155 0.0081 0.0039 0.0081 0.0057 0.0153 0.0018 0.0023 0.0051 0.0109 0.0018 0.0248 0.002 0.0074 0.0069
None 0.0005 0.0001 0.0008 0.0001 0.0006 0.0003 0.0001 0.0001 0.0001 0 0.0001 0.0001 0.001 0.0001 0.0002 0.0001 0.0002 0.0001
Nuclear Periphery 0.0164 0.0068 0.0046 0.0009 0.0045 0.0154 0.0037 0.0028 0.0062 0.0013 0.0093 0.007 0.0207 0.0024 0.0189 0.0025 0.0096 0.0052
Nucleolus 0.0044 0.0024 0.0031 0.0003 0.0004 0.0022 0.0068 0.0032 0.0008 0.0003 0.0067 0.0011 0.0014 0.0015 0.0014 0.0003 0.0004 0.0007
Nucleus 0.0031 0.0017 0.0026 0.0003 0.0008 0.0024 0.0013 0.0009 0.0005 0.0003 0.0005 0.0007 0.0011 0.0008 0.0012 0.0003 0.0007 0.0004
Peroxisomes 0.0011 0.0018 0.0036 0.0131 0.0118 0.0027 0.0026 0.0017 0.0038 0.0004 0.0012 0.0014 0.0087 0.0049 0.0044 0.0044 0.0015 0.0025
Punctate Nuclear 0.0005 0.0002 0.0003 0.0003 0.0037 0.0008 0.0052 0.0003 0.0004 0 0.0003 0.0002 0.0011 0.0002 0.0004 0.0005 0.0004 0.0001
Vacuole 0.1986 0.2405 0.2123 0.2416 0.1649 0.1685 0.1605 0.2231 0.1627 0.1685 0.1998 0.1474 0.1383 0.2144 0.1515 0.21 0.129 0.1473
Vacuole Periphery 0.2444 0.2376 0.2537 0.2208 0.2065 0.2998 0.1791 0.2295 0.1599 0.2207 0.2204 0.2259 0.2063 0.2898 0.2336 0.3362 0.2694 0.3288

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 78.5306 55.0949 60.6648 103.3286 50.2647 63.5845 68.7345 74.5897 84.5179 100.7304
Translational Efficiency 1.4796 1.4562 1.5445 0.933 1.6359 2.4428 1.6158 1.6224 1.6359 1.3054

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1747 198 171 17 1327 2240 2116 607 3074 2438 2287 624

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 873.32 1109.79 1575.68 807.24 902.44 986.07 1430.70 1381.90 885.89 996.12 1441.54 1366.24
Standard Deviation 132.94 198.51 292.80 704.34 155.71 166.56 293.91 335.93 143.94 172.71 296.29 363.38
Intensity Change Log 2 — 0.345704 0.851392 -0.113513 — 0.127859 0.664818 0.614750 — 0.239106 0.759591 0.301928

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000029 0.000141 0.000425 0.000092 0.000053 0.000046 0.000140 0.000592 0.000039 0.000054 0.000161 0.000578
Bud Neck 0.001937 0.001912 0.005562 0.000320 0.002469 0.001713 0.001465 0.001486 0.002167 0.001729 0.001772 0.001455
Bud Site 0.009367 0.011039 0.002247 0.000799 0.008028 0.006424 0.001879 0.004722 0.008789 0.006799 0.001906 0.004615
Cell Periphery 0.000149 0.000217 0.000188 0.000272 0.000155 0.000164 0.000389 0.000572 0.000152 0.000168 0.000374 0.000564
Cytoplasm 0.008254 0.002650 0.000285 0.000150 0.005962 0.003271 0.000533 0.001525 0.007265 0.003221 0.000514 0.001487
Cytoplasmic Foci 0.035471 0.029303 0.024174 0.010014 0.042772 0.030421 0.020531 0.028832 0.038622 0.030331 0.020803 0.028319
Eisosomes 0.000008 0.000008 0.000042 0.000470 0.000013 0.000011 0.000029 0.000036 0.000010 0.000011 0.000030 0.000048
Endoplasmic Reticulum 0.000469 0.001068 0.000615 0.000069 0.000672 0.000698 0.000273 0.000984 0.000556 0.000728 0.000299 0.000959
Endosome 0.273684 0.187611 0.029782 0.020672 0.315262 0.219327 0.099377 0.148192 0.291633 0.216752 0.094173 0.144718
Golgi 0.055207 0.080539 0.049284 0.158730 0.067533 0.074553 0.100494 0.235222 0.060528 0.075039 0.096665 0.233138
Lipid Particles 0.000473 0.000920 0.009912 0.000798 0.001728 0.001415 0.014280 0.014961 0.001015 0.001375 0.013953 0.014575
Mitochondria 0.011652 0.006465 0.050017 0.000547 0.017720 0.026246 0.044915 0.029902 0.014271 0.024639 0.045296 0.029103
Mitotic Spindle 0.002625 0.007442 0.009562 0.002189 0.002142 0.003443 0.001397 0.003516 0.002416 0.003768 0.002007 0.003480
None 0.000245 0.000089 0.000540 0.648148 0.000264 0.000506 0.000437 0.000260 0.000253 0.000472 0.000445 0.017911
Nuclear Periphery 0.000160 0.001796 0.017680 0.000367 0.000425 0.000779 0.003534 0.002616 0.000274 0.000861 0.004592 0.002555
Nuclear Periphery Foci 0.000955 0.005961 0.019459 0.001312 0.001426 0.001862 0.007567 0.009605 0.001158 0.002195 0.008456 0.009379
Nucleolus 0.000493 0.000797 0.002570 0.000026 0.001048 0.001147 0.001329 0.000416 0.000732 0.001119 0.001422 0.000406
Nucleus 0.000606 0.004354 0.006173 0.000011 0.001078 0.000910 0.000305 0.000311 0.000809 0.001189 0.000744 0.000303
Peroxisomes 0.001460 0.001821 0.001458 0.000185 0.004546 0.002014 0.001002 0.001155 0.002792 0.001998 0.001036 0.001129
Vacuole 0.310055 0.349440 0.360108 0.102608 0.273240 0.303646 0.367691 0.290312 0.294163 0.307366 0.367124 0.285198
Vacuole Periphery 0.286701 0.306427 0.409917 0.052223 0.253463 0.321405 0.332435 0.224782 0.272353 0.320188 0.338228 0.220081

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.15 -4.63 -1.86 0.83 3.69 0.49 -2.59 -4.32 -4.38 -3.51 -1.46 -3.98 -4.45 -4.32 -3.33
Bud Neck 0.02 -1.98 4.75 2.08 2.81 1.51 2.24 2.15 0.81 -0.11 1.22 1.13 2.36 1.01 1.31
Bud Site -0.55 6.29 9.10 3.27 1.84 1.30 6.04 2.55 1.62 -3.82 2.11 10.47 4.19 2.14 -3.72
Cell Periphery -0.85 -1.55 -2.21 -0.59 -1.55 -0.34 -5.85 -5.58 -5.36 -2.28 -0.68 -6.22 -5.73 -5.34 -2.45
Cytoplasm 4.32 8.24 8.38 2.93 1.48 2.26 4.94 2.91 1.25 -1.50 4.56 9.14 4.77 1.31 -1.51
Cytoplasmic Foci 1.47 2.60 3.84 2.55 1.84 4.89 9.11 4.29 0.60 -3.11 4.75 10.84 3.86 0.77 -2.89
Eisosomes -0.11 -4.23 -2.31 -2.31 -2.13 1.28 -7.07 -6.52 -7.02 -1.73 -0.96 -9.45 -5.46 -5.31 -2.48
Endoplasmic Reticulum -1.74 -0.73 6.37 2.91 2.51 -0.21 3.60 -1.71 -1.62 -4.56 -1.72 4.01 -2.58 -1.34 -4.33
Endosome 4.91 29.69 18.92 8.32 0.71 10.27 25.40 15.52 7.89 -5.95 10.69 33.33 16.65 8.22 -6.34
Golgi -2.55 0.73 -1.58 -1.18 -1.66 -1.69 -7.09 -14.99 -14.48 -11.91 -4.44 -9.51 -16.01 -14.45 -12.28
Lipid Particles -1.15 -4.20 -0.74 0.19 3.98 0.49 -9.37 -5.32 -5.50 -0.25 -0.89 -10.99 -5.71 -5.51 -0.24
Mitochondria 1.74 -3.53 8.60 2.15 4.57 -3.14 -8.31 -3.08 -0.94 3.54 -5.14 -11.27 -4.24 -1.19 3.92
Mitotic Spindle -1.32 -1.54 0.23 1.33 1.54 -2.14 1.70 -1.44 -0.10 -2.30 -1.99 0.66 -1.13 0.24 -1.56
None 3.60 -3.61 -5.41 -5.42 -5.41 -1.18 -2.89 0.08 1.25 5.68 -1.19 -4.97 -3.34 -3.30 -3.31
Nuclear Periphery -1.20 -4.00 -1.20 1.04 3.95 -2.93 -9.32 -5.07 -4.19 1.71 -3.97 -9.54 -5.48 -3.85 3.32
Nuclear Periphery Foci -1.39 -3.74 -0.49 1.28 3.65 -1.05 -6.77 -3.80 -3.63 -0.95 -2.39 -8.23 -3.96 -3.43 -0.47
Nucleolus -0.70 -3.12 2.62 2.00 3.96 -0.54 -1.00 2.56 2.98 4.34 -1.67 -3.06 1.92 3.09 5.02
Nucleus -0.92 -1.05 3.56 1.07 1.15 0.48 3.19 2.66 2.40 -0.18 -1.00 0.08 2.36 2.18 0.98
Peroxisomes -0.47 0.00 6.92 2.13 3.01 3.46 6.08 5.63 1.96 -0.78 1.55 6.22 5.21 2.11 -0.48
Vacuole -2.32 -2.98 4.81 5.39 5.63 -4.29 -13.31 -1.68 1.29 7.82 -2.36 -13.06 0.87 2.22 8.40
Vacuole Periphery -1.02 -5.89 10.67 9.09 12.29 -7.84 -9.49 2.65 9.47 10.85 -6.94 -10.02 5.48 10.05 12.11
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Vacuolar membrane protein of unknown function; involved in vacuolar protein sorting; also detected in the mitochondria
Localization
Cell Percentages vacuolar membrane (28%), vacuole (9%), mixed (47%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Vps68

Vps68


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Vps68-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available