Standard name
Human Ortholog
Description Peroxisomal protein required for medium-chain fatty acid oxidation; also required for peroxisome proliferation, possibly by inducing membrane curvature; localization regulated by phosphorylation; transcription regulated by Adr1p and Pip2p-Oaf1p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud – 0.08 0 0 0.05 0.11 0.11 0.12 – 0.11 0.15 0.12 0 0 0 0 0 0 0.07 0.13 0.1 0.06 0.07 0.07
Bud Neck – 0.08 0.09 0.06 0.06 0.06 0.06 0 – 0 0 0 0.08 0.05 0.05 0.06 0.08 0 0.11 0.14 0.11 0.06 0.06 0.08
Bud Site – 0 0.22 0.11 0.1 0.15 0.09 0.06 – 0.11 0.12 0.07 0.09 0.07 0.05 0.05 0.05 0.05 – – – – – –
Cell Periphery – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0 0.05 0.06 0 0 0 0 0
Endoplasmic Reticulum – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome – 0.08 0 0 0 0 0 0 – 0 0 0 0 0 0.06 0.06 0.09 0 0 0 0 0.07 0.05 0.05
Golgi – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria – 0.16 0.23 0.14 0.16 0.22 0.19 0.17 – 0.18 0.23 0.23 0.12 0.06 0 0.11 0.07 0.06 0 0 0 0 0 0
Nucleus – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus – 0.28 0.24 0.17 0.19 0.25 0.25 0.24 – 0.18 0.18 0.21 0.22 0.19 0.15 0.37 0.41 0.45 0.08 0.14 0.09 0.09 0.06 0.05
Peroxisomes – 0.4 0.32 0.54 0.45 0.39 0.44 0.36 – 0.54 0.43 0.47 0.29 0.45 0.48 0.2 0.22 0.21 0.1 0.15 0.18 0.29 0.35 0.42
SpindlePole – 0.2 0.46 0.48 0.42 0.4 0.4 0.44 – 0.45 0.41 0.38 0.54 0.54 0.62 0.5 0.49 0.55 0.5 0.31 0.42 0.32 0.29 0.21
Vac/Vac Membrane – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 1 0 0 1 5 4 4 – 3 2 0 11 5 2 0 0 0 0 0 3 3 14 16
Bud – 2 2 8 23 40 63 57 – 54 45 58 13 13 15 6 4 5 1 6 11 7 27 35
Bud Neck – 2 10 16 25 20 31 17 – 11 7 11 25 19 24 14 20 5 2 7 12 8 22 37
Bud Site – 1 25 29 41 53 48 30 – 55 36 32 27 28 24 10 11 8 – – – – – –
Cell Periphery – 0 0 1 1 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm – 0 1 3 8 5 5 10 – 6 3 8 4 3 10 13 8 8 1 0 0 0 0 0
Endoplasmic Reticulum – 0 0 0 0 0 0 1 – 1 0 0 0 0 0 2 1 1 0 0 0 0 1 0
Endosome – 2 4 8 8 0 12 8 – 12 4 15 5 12 28 13 22 7 0 0 2 9 19 25
Golgi – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 0 0 0 0 2 3
Mitochondria – 4 26 36 66 80 106 83 – 92 72 110 36 25 13 25 18 11 0 0 2 1 10 15
Nucleus – 0 0 2 7 4 11 3 – 2 2 5 4 3 4 6 7 6 0 0 0 3 2 2
Nuclear Periphery – 0 0 1 0 0 1 1 – 0 0 1 0 0 0 0 0 0 0 0 0 0 2 0
Nucleolus – 7 27 43 80 88 139 118 – 93 56 99 67 74 72 82 98 79 1 7 10 12 24 26
Peroxisomes – 10 36 136 188 139 246 175 – 276 132 225 90 177 237 44 54 37 2 8 21 41 137 204
SpindlePole – 5 52 122 179 143 226 212 – 231 125 179 166 214 307 110 118 97 11 16 49 44 114 100
Vac/Vac Membrane – 1 1 1 0 1 0 6 – 4 4 3 0 2 3 3 5 0 0 1 0 1 6 4
Unique Cell Count 25 113 254 422 358 562 482 514 308 477 310 394 496 219 241 175 24 55 118 140 396 483
Labelled Cell Count 35 184 406 627 578 892 725 840 488 746 448 575 739 328 367 264 24 55 118 140 396 483


Peroxisomes

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) – 10.5 8.4 9.8 9.2 8.8 8.8 9.2 – 10.1 9.3 9.8 10.8 10.9 10.5 15.1 15.6 14.9 10.5 10.6 10.8
Std Deviation (1e-4) – 3.9 4.8 6.2 4.9 5.4 5.7 5.8 – 7.4 5.2 6.3 4.5 5.0 4.3 12.1 13.2 12.0 4.7 5.7 5.0
Intensity Change (Log2) – – – 0.22 0.13 0.06 0.06 0.12 – 0.26 0.13 0.22 0.35 0.37 0.32 0.84 0.89 0.82 0.31 0.33 0.36

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP70001020WT3HU80HU120HU16001020WT3rpd3Δ_1rpd3Δ_2rpd3Δ_301020AF100AF140AF18001020
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud 0 1.6 3.1 3.1 3.2 – 2.9 3.7 3.3 0 0 0 0 0 0
Bud Neck -0.9 -1.1 -1.2 -1.4 -2.4 – 0 0 0 -0.3 -1.6 -1.7 -0.8 -0.2 -2.2
Bud Site -2.7 -3.6 -1.8 -4.2 -5.3 – -3.3 -2.7 -5.0 -3.7 -4.6 -6.1 -4.9 -5.1 -4.6
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 – 0 0 0 0 0 0.9 0.9 1.9 0
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria -2.1 -1.8 -0.1 -1.0 -1.4 – -1.3 0.1 0 -2.9 -5.2 -8.0 -2.8 -4.1 -4.1
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus -1.6 -1.2 0.1 0.2 0.1 – -1.4 -1.3 -0.7 -0.5 -1.2 -2.4 2.5 3.1 3.7
Peroxisomes 3.8 2.4 1.3 2.3 0.9 – 4.2 2.0 2.9 -0.6 2.5 3.1 -2.4 -1.9 -2.0
SpindlePole 0.4 -0.7 -1.1 -1.1 -0.4 – -0.2 -1.0 -1.7 1.4 1.6 3.1 0.7 0.5 1.6
Vacuole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 9.488 11.6846 11.4685 11.0743 11.6643 11.2928 10.3688 10.3283 11.1185 10.0807 9.0966 9.5428 8.7317 12.8838 10.7963 10.4845 9.1358 11.078
Actin 0.0176 0.0108 0.0312 0.0025 0.0071 0.0041 0.0185 0.0016 0.0112 0.0003 0.0133 0.0007 0.0174 0.0061 0.0282 0.0015 0.0299 0.01
Bud 0.0009 0.0097 0.005 0.0009 0.0002 0.0004 0.0004 0.0049 0.0044 0.0003 0.0001 0.0004 0.0006 0.0192 0.0067 0.0002 0.0028 0.0003
Bud Neck 0.0034 0.0092 0.0341 0.0241 0.0007 0.0526 0.0034 0.005 0.0454 0.056 0.0139 0.0066 0.0012 0.003 0.027 0.0486 0.0051 0.0147
Bud Periphery 0.001 0.0058 0.0032 0.0005 0.0002 0.0003 0.0003 0.0013 0.0022 0.0002 0.0001 0.0004 0.0007 0.0067 0.0026 0.0001 0.0026 0.0002
Bud Site 0.0094 0.0777 0.0359 0.0036 0.0006 0.0017 0.0059 0.0682 0.0219 0.0043 0.0005 0.0016 0.0102 0.0409 0.0259 0.0007 0.0033 0.0013
Cell Periphery 0.0007 0.0032 0.0012 0.0007 0.0004 0.0006 0.0006 0.0018 0.0015 0.0007 0.0003 0.0003 0.001 0.0017 0.0017 0.0006 0.0009 0.0005
Cytoplasm 0.0013 0.0003 0.0006 0.0001 0.0001 0.0001 0.0017 0.0008 0.0003 0 0.0026 0 0.0009 0.0006 0.0002 0.0006 0.0008 0.0001
Cytoplasmic Foci 0.2301 0.277 0.253 0.2589 0.1416 0.2406 0.2048 0.2904 0.2367 0.2221 0.2861 0.2942 0.2101 0.2451 0.231 0.2771 0.2286 0.2813
Eisosomes 0.0008 0.0002 0.0003 0.0004 0.0001 0.0002 0.0005 0.0002 0.0003 0.0001 0.0003 0.0001 0.0007 0.0002 0.0005 0.0003 0.0002 0.0003
Endoplasmic Reticulum 0.0061 0.0001 0.0001 0 0.0001 0 0.0009 0 0.0001 0 0.0085 0 0.0003 0.0001 0.0001 0.0012 0.0003 0
Endosome 0.0291 0.004 0.004 0.0037 0.0109 0.0009 0.0072 0.0018 0.004 0.0005 0.018 0.0008 0.0073 0.0073 0.0019 0.0187 0.021 0.001
Golgi 0.0125 0.0047 0.0076 0.0086 0.0365 0.0046 0.0049 0.0035 0.0033 0.0027 0.0115 0.0035 0.0055 0.0115 0.0039 0.0041 0.0276 0.0068
Lipid Particles 0.1457 0.0852 0.1082 0.1791 0.1988 0.1793 0.1329 0.0992 0.0891 0.2711 0.1693 0.2026 0.1999 0.1184 0.1043 0.1711 0.2093 0.1978
Mitochondria 0.1254 0.0753 0.0751 0.0808 0.1057 0.0644 0.1602 0.0853 0.1242 0.059 0.1056 0.0554 0.1136 0.0917 0.1439 0.1303 0.0604 0.1134
None 0.0016 0.0002 0.0002 0.0001 0.0001 0.0001 0.0073 0.0021 0.0004 0 0.0036 0.0001 0.0082 0.0004 0.0009 0.0011 0.0003 0
Nuclear Periphery 0.0028 0.0001 0.0002 0 0.0001 0 0.0017 0 0.0001 0 0.0014 0 0.0023 0.0002 0.0001 0.0022 0.0002 0
Nucleolus 0.0588 0.089 0.0881 0.0941 0.0587 0.038 0.0702 0.1189 0.0542 0.0288 0.0348 0.0412 0.0673 0.0982 0.0621 0.0555 0.1534 0.0214
Nucleus 0.0017 0.0051 0.0156 0.003 0.0014 0.0009 0.0019 0.0035 0.0028 0.0009 0.0009 0.0008 0.0033 0.0172 0.0029 0.0018 0.0083 0.0006
Peroxisomes 0.3446 0.3116 0.3321 0.3056 0.4342 0.4093 0.3579 0.2985 0.3846 0.3511 0.3073 0.3876 0.3289 0.2976 0.3459 0.2796 0.2391 0.3483
Punctate Nuclear 0.0017 0.0146 0.0026 0.0322 0.0005 0.0009 0.0173 0.0038 0.0093 0.0009 0.021 0.003 0.0065 0.0032 0.008 0.0019 0.0024 0.0008
Vacuole 0.0028 0.011 0.0011 0.0006 0.0012 0.0006 0.0009 0.0054 0.003 0.0006 0.0006 0.0005 0.0086 0.0176 0.0016 0.0017 0.0026 0.0007
Vacuole Periphery 0.002 0.0052 0.0004 0.0004 0.0009 0.0004 0.0006 0.0036 0.001 0.0003 0.0004 0.0003 0.0054 0.0131 0.0005 0.0009 0.001 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 96.9941 51.3304 32.9422 36.3202 50.3028 80.6544 63.1218 43.5497 41.5117 64.8505
Translational Efficiency 1.3589 1.5771 1.5294 1.323 1.5855 2.1867 1.3355 1.4386 1.8424 1.3938

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
106 1260 714 922 1630 1433 2439 1716 1736 2693 3153 2638

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 877.81 1104.59 1163.74 1434.36 909.70 1104.00 1316.98 1499.11 907.75 1104.28 1282.28 1476.48
Standard Deviation 180.48 362.24 289.88 432.56 307.56 337.40 437.84 459.85 301.44 349.24 414.05 451.55
Intensity Change Log 2 — 0.331530 0.406788 0.708427 — 0.279277 0.533771 0.720643 — 0.305174 0.472808 0.714657

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.004309 0.006544 0.015445 0.017555 0.005596 0.007225 0.008067 0.028926 0.005518 0.006906 0.009738 0.024952
Bud Neck 0.015091 0.015519 0.019621 0.022912 0.015980 0.022575 0.012758 0.015681 0.015926 0.019274 0.014312 0.018208
Bud Site 0.094950 0.062772 0.070275 0.107767 0.050867 0.073928 0.058361 0.082673 0.053559 0.068708 0.061059 0.091443
Cell Periphery 0.001160 0.000399 0.000222 0.000336 0.000482 0.000494 0.000296 0.000382 0.000524 0.000449 0.000279 0.000366
Cytoplasm 0.016843 0.012825 0.011317 0.017530 0.014372 0.013912 0.017885 0.020453 0.014523 0.013403 0.016398 0.019431
Cytoplasmic Foci 0.298426 0.326653 0.300169 0.307981 0.271504 0.328444 0.236612 0.233074 0.273147 0.327606 0.251005 0.259255
Eisosomes 0.000624 0.002558 0.001270 0.001556 0.002462 0.001987 0.002636 0.001725 0.002349 0.002254 0.002327 0.001666
Endoplasmic Reticulum 0.000727 0.000329 0.000329 0.000198 0.000381 0.000421 0.000156 0.000207 0.000402 0.000378 0.000195 0.000204
Endosome 0.019502 0.004297 0.006578 0.006789 0.005504 0.007162 0.001614 0.004212 0.006358 0.005822 0.002738 0.005113
Golgi 0.020167 0.008593 0.010224 0.011215 0.013755 0.009646 0.002829 0.011737 0.014147 0.009153 0.004504 0.011554
Lipid Particles 0.008203 0.008517 0.008460 0.007042 0.009610 0.010677 0.003073 0.007007 0.009524 0.009667 0.004293 0.007019
Mitochondria 0.013370 0.020795 0.016148 0.049201 0.019430 0.034759 0.048813 0.057847 0.019060 0.028226 0.041416 0.054825
Mitotic Spindle 0.012687 0.009382 0.050564 0.035294 0.006528 0.018752 0.018848 0.022136 0.006904 0.014368 0.026030 0.026735
None 0.003105 0.000546 0.000191 0.000351 0.001445 0.000595 0.000443 0.000402 0.001546 0.000572 0.000386 0.000384
Nuclear Periphery 0.000051 0.000069 0.000241 0.000193 0.000057 0.000155 0.000115 0.000137 0.000056 0.000115 0.000143 0.000156
Nuclear Periphery Foci 0.002018 0.001066 0.001352 0.000521 0.001860 0.001741 0.000314 0.000264 0.001870 0.001425 0.000549 0.000354
Nucleolus 0.006452 0.006918 0.003867 0.003496 0.005019 0.006182 0.003649 0.002725 0.005107 0.006526 0.003698 0.002995
Nucleus 0.002011 0.003055 0.001488 0.001862 0.003568 0.002705 0.001451 0.001954 0.003473 0.002869 0.001460 0.001922
Peroxisomes 0.476733 0.504989 0.477968 0.400241 0.567489 0.452862 0.579792 0.504861 0.561947 0.477251 0.556734 0.468295
Vacuole 0.003273 0.003765 0.003781 0.006782 0.003816 0.005090 0.001954 0.002994 0.003783 0.004470 0.002368 0.004318
Vacuole Periphery 0.000297 0.000409 0.000491 0.001179 0.000275 0.000689 0.000333 0.000602 0.000277 0.000558 0.000368 0.000804

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.64 -4.10 -5.32 -4.52 -0.60 -1.22 -2.51 -9.40 -8.17 -8.24 -1.45 -4.19 -10.52 -9.48 -7.84
Bud Neck -0.18 -1.59 -2.34 -3.73 -1.27 -3.91 2.33 -0.04 4.45 -3.10 -2.49 1.08 -1.90 0.74 -3.98
Bud Site 1.87 1.36 -0.81 -6.70 -4.97 -4.98 -2.11 -7.12 -1.95 -5.53 -3.93 -2.23 -9.21 -5.91 -7.93
Cell Periphery 1.06 1.27 1.10 0.51 -2.58 -0.13 3.01 0.94 0.91 -1.26 0.95 3.39 1.69 0.91 -1.80
Cytoplasm 1.07 1.31 -0.11 -3.64 -4.08 0.53 -2.98 -4.26 -4.72 -1.94 1.37 -1.77 -4.24 -6.08 -2.91
Cytoplasmic Foci -0.83 0.02 -0.36 1.13 -0.81 -5.49 3.83 3.81 9.30 0.26 -6.18 2.54 1.23 8.36 -1.46
Eisosomes -7.96 -4.64 -5.21 3.76 -1.40 2.27 -0.65 4.08 1.46 4.11 0.53 0.17 4.24 3.78 3.80
Endoplasmic Reticulum 1.24 1.20 1.69 2.18 2.29 -0.31 5.15 3.95 2.32 -1.42 0.48 4.49 4.60 3.04 -0.11
Endosome 2.15 1.81 1.78 -1.83 -0.09 -1.44 5.91 1.66 2.73 -4.52 0.58 4.68 1.43 0.89 -3.96
Golgi 2.55 2.18 1.92 -1.26 -0.42 2.89 10.23 1.31 -1.22 -6.69 4.11 9.09 1.93 -1.83 -6.48
Lipid Particles 0.05 0.08 0.45 0.76 0.86 -0.47 4.93 1.79 2.03 -4.01 -0.01 4.15 1.90 2.02 -3.19
Mitochondria -1.32 -0.50 -5.10 -5.68 -6.80 -4.45 -9.32 -10.38 -5.26 -2.09 -3.62 -8.33 -11.43 -8.20 -3.87
Mitotic Spindle 0.62 -4.69 -3.21 -7.16 2.41 -5.73 -8.22 -7.89 -1.12 -1.56 -5.16 -10.82 -10.54 -5.93 -0.38
None 1.07 1.21 1.15 2.00 -3.49 2.38 3.00 3.10 1.30 0.61 2.77 3.36 3.35 2.03 -0.06
Nuclear Periphery -1.01 -5.39 -6.10 -6.68 1.44 -5.32 -2.91 -8.05 0.76 -0.95 -5.45 -5.08 -10.59 -3.40 -0.56
Nuclear Periphery Foci 1.47 0.82 2.33 3.25 1.99 0.65 5.20 5.36 5.34 1.02 1.71 4.50 5.36 6.49 1.88
Nucleolus -0.17 0.55 0.70 2.82 0.47 -1.37 1.90 3.04 4.26 1.44 -1.80 1.85 2.85 5.11 1.28
Nucleus -1.28 0.25 -0.29 1.01 -0.60 1.03 2.71 1.17 0.36 -1.56 0.82 2.68 1.33 0.89 -1.73
Peroxisomes -0.92 0.03 2.26 7.69 4.85 9.44 -0.98 5.74 -3.99 7.33 8.11 0.77 9.44 1.52 10.25
Vacuole -0.48 -0.99 -2.51 -2.48 -1.82 -1.75 4.01 1.19 2.75 -3.04 -1.23 2.75 -1.19 -0.05 -3.76
Vacuole Periphery -0.75 -1.20 -2.49 -2.28 -1.74 -3.23 -0.63 -3.45 0.50 -2.33 -3.17 -1.18 -3.90 -1.76 -2.89
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Peroxisomal protein required for medium-chain fatty acid oxidation; also required for peroxisome proliferation, possibly by inducing membrane curvature; localization regulated by phosphorylation; transcription regulated by Adr1p and Pip2p-Oaf1p
Localization
Cell Percentages peroxisome (31%), mitochondrion (10%), mixed (34%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Pex11

Pex11


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pex11-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available