Standard name
Human Ortholog
Description B-type regulatory subunit of protein phosphatase 2A (PP2A); Rts1p and Cdc55p are alternative regulatory subunits for PP2A catalytic subunits, Pph21p and Pph22p; PP2A-Rts1p protects cohesin when recruited by Sgo1p to the pericentromere; highly enriched at centromeres in the absence of Cdc55p; required for maintenance of septin ring organization during cytokinesis, for ring disassembly in G1 and for dephosphorylation of septin, Shs1p; homolog of the mammalian B' subunit of PP2A
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.12 0.1 0.23 0.21 0.16 0.21 0.25 0.27 0.26 0.33 0.22 0.3 0.2 0.35 0.39 0.1 0.11 0.1 0 0 0 0.08 0.16 0.13
Cytoplasm 0.9 0.94 0.86 0.85 0.73 0.78 0.77 0.8 0.79 0.76 0.74 0.7 0.83 0.8 0.8 0.84 0.8 0.85 0.83 0.9 0.87 0.84 0.72 0.73
Endoplasmic Reticulum 0.08 0 0.07 0.09 0.21 0.14 0.12 0.12 0.08 0.08 0.08 0.06 0.14 0.13 0.12 0 0 0 0.08 0 0 0 0.05 0.07
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0.08 0.06 0.1 0.12 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0.08 0 0 0 0.11 0.1 0.1 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 1 0 1 2 2 2 3 4 3 1 0 0 1 1 0 0 2 1 1 2 2
Bud 0 2 2 1 0 0 3 2 2 2 3 1 1 0 1 0 1 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 3 6 1 2 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 9 21 55 35 34 56 87 92 72 99 41 71 37 69 72 14 15 13 2 3 10 7 33 23
Cytoplasm 69 193 202 145 151 207 264 272 216 230 136 166 156 156 148 118 107 110 76 199 227 84 148 129
Endoplasmic Reticulum 6 8 17 16 44 38 42 40 21 25 15 15 27 26 22 3 3 3 7 3 8 3 9 13
Endosome 0 0 0 0 0 0 3 0 0 0 0 0 1 1 0 0 0 1 0 1 0 0 1 1
Golgi 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
Mitochondria 0 0 0 0 0 4 8 8 21 18 18 28 0 0 0 2 0 1 0 0 1 1 0 0
Nucleus 0 10 6 3 2 2 4 4 5 3 0 2 2 0 6 6 7 5 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
Vac/Vac Membrane 0 1 0 0 4 7 8 13 4 6 6 19 0 0 0 16 14 13 0 2 2 1 1 0
Unique Cell Count 77 205 235 170 208 267 344 339 274 301 184 237 189 195 184 140 134 130 92 221 262 101 206 176
Labelled Cell Count 85 235 282 201 236 316 421 434 344 386 224 305 226 252 249 160 148 146 92 221 262 101 206 176


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 13.3 13.2 11.3 10.8 12.3 10.5 10.7 10.6 9.8 9.8 8.8 9.8 11.8 11.9 12.0 15.2 16.7 16.0 10.7 11.4 13.2
Std Deviation (1e-4) 1.7 2.3 1.7 1.8 1.8 1.8 1.6 1.7 1.8 2.0 1.7 1.8 2.2 2.1 1.9 3.6 4.2 3.8 1.8 1.9 2.1
Intensity Change (Log2) – – – -0.06 0.13 -0.1 -0.07 -0.09 -0.21 -0.2 -0.36 -0.21 0.06 0.08 0.08 0.43 0.56 0.5 -0.08 0.02 0.23


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -0.7 -1.9 -0.7 0.5 1.0 0.7 2.4 -0.3 1.6 -1.0 2.7 3.5 -3.2 -2.9 -3.1
Cytoplasm -0.2 -3.5 -2.4 -2.7 -1.8 -2.1 -2.8 -3.1 -4.2 -1.0 -1.6 -1.5 -0.4 -1.5 -0.3
Endoplasmic Reticulum 0.8 4.2 2.5 1.9 1.8 0.2 0.5 0.4 -0.4 2.4 2.1 1.7 -2.1 -2.0 -2.0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 4.3 3.8 4.9 5.4 0 0 0 0 0 0
Nucleus 0 0 0 0 0 -0.6 0 0 0 0 0 0.4 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 3.0 0 0 0 4.4 0 0 0 5.3 5.1 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.8816 8.0358 7.4586 6.6487 5.6509 7.0594 7.3196 9.9692 8.3512 7.9321 8.5157 8.8693 6.8539 8.8638 7.6976 8.1452 7.9864 8.2096
Actin 0.0486 0.0026 0.0036 0.003 0.0243 0.0102 0.0173 0.0021 0.0111 0.0018 0.001 0.0034 0.027 0.0028 0.0219 0.0039 0.0012 0.0122
Bud 0.0012 0.0007 0.0002 0.0001 0.0014 0.0003 0.0005 0.0001 0.0007 0.0003 0.0001 0.0001 0.0005 0.0002 0.0003 0.0003 0.0001 0.0001
Bud Neck 0.0029 0.0012 0.0038 0.0034 0.005 0.0246 0.0031 0.0034 0.0112 0.0049 0.006 0.0139 0.001 0.0033 0.0041 0.0093 0.0037 0.0088
Bud Periphery 0.0013 0.0003 0.0001 0.0001 0.0017 0.0005 0.0006 0.0001 0.0012 0.0006 0.0001 0.0001 0.0009 0.0001 0.0003 0.0003 0.0001 0.0001
Bud Site 0.0126 0.0106 0.0029 0.0004 0.0032 0.0005 0.0022 0.0032 0.0102 0.0005 0.0005 0.0002 0.0013 0.0152 0.004 0.0009 0.0001 0.0002
Cell Periphery 0.0013 0.0021 0.0016 0.0004 0.0012 0.0018 0.0021 0.0042 0.0024 0.0009 0.0018 0.001 0.0016 0.0018 0.002 0.002 0.0013 0.0004
Cytoplasm 0.7453 0.9601 0.892 0.9549 0.71 0.8918 0.7699 0.9559 0.834 0.9049 0.9632 0.939 0.8427 0.9531 0.8499 0.8618 0.9839 0.9209
Cytoplasmic Foci 0.0225 0.0015 0.012 0.0015 0.0082 0.0048 0.0412 0.0046 0.0151 0.0008 0.0018 0.0021 0.0187 0.0018 0.0255 0.017 0.0008 0.0049
Eisosomes 0.0005 0 0 0 0.0001 0 0.0002 0 0.0001 0 0 0.0001 0.0002 0 0.0005 0 0 0.0001
Endoplasmic Reticulum 0.0293 0.0043 0.0121 0.0085 0.0315 0.0131 0.0177 0.0093 0.0135 0.0086 0.0154 0.0092 0.0138 0.0043 0.0086 0.0094 0.0038 0.0099
Endosome 0.021 0.0003 0.0012 0.0008 0.0697 0.0167 0.0362 0.0004 0.0211 0.0076 0.0004 0.0067 0.0197 0.0002 0.0051 0.0005 0.0001 0.0062
Golgi 0.0075 0.0002 0.0008 0.0001 0.0277 0.0037 0.0108 0.0002 0.0051 0.0027 0.0001 0.0037 0.0115 0.0002 0.0081 0.0002 0 0.004
Lipid Particles 0.0185 0.0003 0.0019 0.0002 0.0041 0.0045 0.0085 0.0008 0.0093 0.0005 0.0007 0.0022 0.0274 0.0003 0.0024 0.0006 0.0002 0.0064
Mitochondria 0.0229 0.0001 0.0176 0.0001 0.0284 0.0021 0.0127 0 0.0043 0.0451 0 0.001 0.0052 0 0.004 0.0001 0 0.0014
None 0.0048 0.0013 0.0018 0.0028 0.0046 0.0015 0.0149 0.0011 0.0017 0.0006 0.0007 0.0006 0.0038 0.0011 0.0155 0.0079 0.0005 0.0009
Nuclear Periphery 0.0289 0.0016 0.0043 0.0039 0.0527 0.0115 0.0128 0.0016 0.0045 0.0022 0.0016 0.003 0.0049 0.0007 0.0024 0.0025 0.0005 0.0028
Nucleolus 0.0006 0.0001 0.0002 0 0.0003 0.0003 0.0013 0.0001 0.0014 0.0001 0 0.0001 0.0001 0.0001 0.0002 0.001 0 0.0001
Nucleus 0.0061 0.0115 0.0317 0.018 0.0129 0.006 0.0206 0.0085 0.035 0.0122 0.0051 0.0066 0.0029 0.0134 0.0135 0.031 0.0033 0.0037
Peroxisomes 0.0104 0 0.0003 0 0.0015 0.0007 0.0046 0.0001 0.0025 0.0001 0 0.0044 0.0113 0.0001 0.0144 0.0004 0 0.0116
Punctate Nuclear 0.0089 0.0005 0.0102 0.001 0.003 0.0034 0.0132 0.0035 0.0104 0.0005 0.0008 0.0006 0.0038 0.0008 0.0164 0.0501 0.0002 0.0049
Vacuole 0.0028 0.0007 0.0015 0.0007 0.005 0.0012 0.0087 0.0009 0.0045 0.0025 0.0007 0.0013 0.0012 0.0003 0.0009 0.0009 0.0003 0.0003
Vacuole Periphery 0.0022 0 0.0001 0 0.0036 0.0008 0.0011 0 0.0006 0.0025 0 0.0004 0.0006 0 0.0001 0 0 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 58.7124 38.1711 40.8776 63.9732 43.7236 50.4356 51.8617 57.8699 52.4578 64.1831
Translational Efficiency 1.0411 1.1856 1.1788 0.7398 1.0048 1.3355 0.8897 0.8362 1.0248 0.8332

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
751 192 169 1399 1529 1221 1459 174 2280 1413 1628 1573

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1080.20 1252.90 1797.12 1549.18 1164.06 1168.09 1512.78 1707.65 1136.44 1179.61 1542.30 1566.71
Standard Deviation 157.38 199.40 213.11 250.22 184.65 209.89 218.36 362.49 180.49 210.51 234.45 269.61
Intensity Change Log 2 — 0.213973 0.734388 0.520206 — 0.004986 0.378037 0.552847 — 0.109357 0.560548 0.537229

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.007374 0.007074 0.016950 0.012224 0.005140 0.002092 0.005947 0.008023 0.005876 0.002769 0.007089 0.011760
Bud Neck 0.009472 0.010431 0.076432 0.015642 0.009369 0.006127 0.018517 0.019353 0.009403 0.006711 0.024529 0.016053
Bud Site 0.085355 0.081632 0.077995 0.097296 0.060355 0.025095 0.051990 0.086743 0.068589 0.032777 0.054689 0.096129
Cell Periphery 0.008028 0.006501 0.026370 0.001272 0.005991 0.001467 0.005632 0.012091 0.006662 0.002151 0.007785 0.002469
Cytoplasm 0.593412* 0.528850* 0.131108* 0.343239* 0.638965* 0.647587* 0.479413* 0.338484* 0.623960* 0.631453* 0.443256* 0.342713*
Cytoplasmic Foci 0.108767 0.116758 0.032533 0.050883 0.080906 0.057485 0.026744 0.063756 0.090083 0.065539 0.027345 0.052307
Eisosomes 0.001564 0.000822 0.000713 0.000123 0.001083 0.000342 0.000467 0.001518 0.001242 0.000407 0.000492 0.000278
Endoplasmic Reticulum 0.008629 0.011329 0.015601 0.002408 0.007318 0.004253 0.004440 0.003458 0.007750 0.005214 0.005598 0.002524
Endosome 0.001548 0.003352 0.005435 0.027251 0.001324 0.003821 0.001740 0.034585 0.001398 0.003757 0.002124 0.028062
Golgi 0.001549 0.000887 0.001353 0.028712 0.001191 0.001735 0.001162 0.009887 0.001309 0.001619 0.001182 0.026629
Lipid Particles 0.005201 0.008095 0.042829 0.004393 0.005429 0.002440 0.006201 0.010783 0.005354 0.003209 0.010003 0.005100
Mitochondria 0.000792 0.000098 0.001249 0.005002 0.000793 0.000773 0.000260 0.000328 0.000793 0.000681 0.000363 0.004485
Mitotic Spindle 0.002054 0.000961 0.002627 0.156766* 0.000953 0.006494 0.019345 0.023235 0.001316 0.005742 0.017610 0.141995*
None 0.002688 0.000497 0.001541 0.011674 0.005338 0.005650 0.003423 0.004878 0.004465 0.004949 0.003228 0.010922
Nuclear Periphery 0.000202 0.000175 0.001744 0.000711 0.000097 0.000175 0.000575 0.000369 0.000132 0.000175 0.000696 0.000673
Nuclear Periphery Foci 0.011675 0.013167 0.010097 0.003925 0.011226 0.006522 0.005804 0.004030 0.011374 0.007425 0.006250 0.003937
Nucleolus 0.000245 0.000087 0.000136 0.000796 0.000146 0.000520 0.000080 0.000294 0.000179 0.000461 0.000086 0.000740
Nucleus 0.090462 0.089868 0.293193* 0.080575 0.102856 0.142118* 0.193269* 0.195959* 0.098773 0.135018* 0.203642* 0.093338
Peroxisomes 0.000930 0.000879 0.000283 0.006718 0.000705 0.000858 0.000436 0.000869 0.000779 0.000861 0.000420 0.006071
Vacuole 0.059010 0.118420 0.261545* 0.133258 0.060416 0.083694 0.174316 0.181129 0.059953 0.088412 0.183371 0.138554
Vacuole Periphery 0.001045 0.000118 0.000267 0.017132 0.000400 0.000756 0.000240 0.000227 0.000612 0.000669 0.000243 0.015262

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.53 -3.03 2.72 1.73 4.40 8.56 0.20 -0.39 -5.40 -0.52 8.80 0.02 1.39 -4.77 1.29
Bud Neck -0.35 -15.13 -0.82 -0.09 15.01 4.15 -6.46 -4.74 -5.80 -2.19 4.04 -11.77 -3.29 -6.30 8.91
Bud Site 1.05 0.47 6.97 3.42 6.07 11.79 5.51 -1.60 -7.07 -4.23 12.52 7.54 5.12 -6.56 -1.55
Cell Periphery 1.53 -7.75 9.33 3.97 12.27 9.83 3.83 0.42 -3.48 -1.23 10.89 1.53 11.69 0.81 11.61
Cytoplasm 3.83 36.95 21.73 8.49 -19.42 2.05 27.75 17.72 16.43 5.69 2.08 31.77 34.82 28.33 3.06
Cytoplasmic Foci 0.24 11.40 16.24 10.90 3.31 3.75 18.60 5.89 3.32 -3.59 5.20 23.30 22.22 14.39 0.07
Eisosomes 2.80 4.79 7.66 2.90 9.54 9.54 9.61 2.86 -0.80 -0.62 9.80 10.69 12.89 4.03 6.66
Endoplasmic Reticulum -1.16 -2.67 7.00 5.25 9.93 4.27 4.84 6.91 4.19 4.71 3.93 4.79 10.95 8.99 14.03
Endosome -2.95 -7.53 -2.78 -0.71 1.10 -2.47 -0.07 -0.86 -0.40 -0.85 -2.70 -2.17 -3.00 -0.72 -2.66
Golgi 2.44 1.84 -2.28 -3.21 -2.99 -0.31 3.12 -0.24 -0.07 -0.99 0.07 3.62 -2.63 -2.36 -3.59
Lipid Particles -1.14 -8.26 0.01 1.24 8.38 5.61 -2.34 -3.29 -6.19 -1.99 4.01 -6.74 -0.60 -5.54 6.79
Mitochondria 1.47 -1.10 -0.37 -2.50 0.82 0.27 0.81 0.82 1.11 0.17 0.51 0.85 -0.28 -0.96 -1.49
Mitotic Spindle -0.60 -0.82 -8.75 -7.94 -7.48 -3.30 -6.18 -2.44 -1.40 0.14 -3.04 -5.96 -9.69 -7.80 -5.17
None 4.98 3.80 -2.20 -4.89 -4.36 0.21 3.05 2.50 2.72 -0.30 -0.04 3.13 -0.19 -0.16 -2.50
Nuclear Periphery -0.35 -12.99 -7.49 -14.27 9.61 -10.11 -18.85 -8.25 -6.69 1.18 -2.85 -17.55 -16.63 -18.29 1.66
Nuclear Periphery Foci -0.04 2.11 9.31 5.32 7.34 3.50 6.67 7.19 4.52 1.78 3.73 8.03 13.28 9.76 8.18
Nucleolus 0.87 0.89 -0.19 -1.70 -2.27 -2.02 4.83 -0.07 1.82 -0.72 -1.71 2.00 -1.32 1.12 -3.19
Nucleus -0.59 -10.16 -8.11 -4.95 7.55 -7.71 -16.48 -4.59 -2.00 1.34 -8.43 -20.09 -8.70 -0.91 9.94
Peroxisomes 0.45 9.02 -0.90 -1.04 -2.98 -0.78 2.30 3.07 2.74 -0.13 -0.43 3.34 -1.22 -0.94 -2.55
Vacuole -6.96 -16.62 -37.59 -16.36 -4.07 -8.54 -32.77 -13.74 -11.70 -3.55 -10.89 -36.53 -41.16 -31.25 -8.50
Vacuole Periphery 1.88 1.61 -1.41 -2.99 -2.80 -0.57 1.23 1.37 2.05 0.68 0.27 2.14 -2.09 -2.22 -2.96
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description B-type regulatory subunit of protein phosphatase 2A (PP2A); Rts1p and Cdc55p are alternative regulatory subunits for PP2A catalytic subunits, Pph21p and Pph22p; PP2A-Rts1p protects cohesin when recruited by Sgo1p to the pericentromere; highly enriched at centromeres in the absence of Cdc55p; required for maintenance of septin ring organization during cytokinesis, for ring disassembly in G1 and for dephosphorylation of septin, Shs1p; homolog of the mammalian B' subunit of PP2A
Localization
Cell Percentages cytoplasm (95%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-10

Rts1

Rts1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rts1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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