Standard name
Human Ortholog
Description Protein with a role in 5'-end processing of mitochondrial RNAs; located in the mitochondrial membrane
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0.07 0.1 0.1 – – 0.06 0 0 0 0 0.05 0
Bud 0 0.05 0 0 0 0 0 0 – 0 0 0.05 0 0 0 – – 0.08 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0.06 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 – 0 0 0 0 0.06 0.19 – – 0.21 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0.11 0.1 0.19 – – 0.08 0 0 0 0 0 0
Endosome 0.12 0 0.07 0 0.1 0 0 0 – 0 0 0 0.11 0.16 0.14 – – 0.19 0.08 0.1 0.08 0.13 0.06 0.11
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0.1 0.08 – – 0.08 0 0 0 0 0.08 0.06
Mitochondria 0.78 0.94 0.86 0.94 0.86 0.93 0.93 0.91 – 0.97 0.96 0.97 0.53 0.44 0.24 – – 0.14 0.74 0.66 0.7 0.61 0.59 0.58
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0.06 0.07 0 0 0 – – 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0.06 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Peroxisomes 0 0 0.17 0.05 0.06 0 0 0 – 0 0 0 0 0 0 – – 0.08 0.06 0.05 0.12 0.11 0.12 0.16
SpindlePole 0 0 0.08 0 0.05 0 0 0 – 0 0 0 0.05 0.05 0 – – 0.15 0 0 0 0 0 0
Vac/Vac Membrane 0.16 0.07 0 0 0.05 0.05 0.05 0 – 0 0 0 0.18 0.14 0.11 – – 0.06 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 6 0 3 0 0 0 0 – 0 0 0 4 8 12 – – 6 2 7 9 1 11 6
Bud 2 15 18 17 7 8 19 26 – 23 26 32 2 0 1 – – 8 1 1 1 2 1 1
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 1 – – 2 1 4 0 2 1 0
Bud Site 1 1 1 3 2 3 10 13 – 13 13 11 0 0 0 – – 1 – – – – – –
Cell Periphery 5 2 15 8 3 2 2 1 – 1 4 3 1 3 5 – – 6 0 1 1 0 0 1
Cytoplasm 10 13 21 15 15 18 13 23 – 11 9 4 2 5 22 – – 20 0 3 2 0 1 0
Endoplasmic Reticulum 2 9 4 2 4 2 2 2 – 4 6 4 6 8 23 – – 8 0 0 2 0 1 0
Endosome 42 2 46 7 47 4 3 7 – 0 1 1 6 13 16 – – 18 33 39 51 19 15 29
Golgi 11 2 2 2 2 0 0 0 – 0 0 0 2 8 9 – – 8 17 15 23 4 20 14
Mitochondria 281 309 545 425 386 406 494 675 – 542 659 689 29 35 28 – – 13 299 247 457 96 150 146
Nucleus 2 4 2 1 3 7 7 21 – 9 7 4 2 2 0 – – 2 0 1 0 0 2 0
Nuclear Periphery 8 9 6 9 6 17 17 31 – 22 40 50 1 0 0 – – 1 6 1 4 4 0 2
Nucleolus 4 2 8 4 10 16 23 43 – 17 28 26 0 0 0 – – 0 1 3 1 0 1 0
Peroxisomes 13 3 105 24 25 9 11 19 – 8 2 5 0 0 1 – – 8 25 19 79 17 31 39
SpindlePole 13 5 48 15 21 15 16 33 – 17 14 9 3 4 5 – – 14 4 6 6 2 2 2
Vac/Vac Membrane 59 23 23 7 21 21 24 32 – 24 19 27 10 11 13 – – 6 6 14 3 1 6 4
Unique Cell Count 362 328 634 451 449 437 531 743 557 683 709 55 80 118 95 404 372 657 157 255 253
Labelled Cell Count 453 405 844 542 552 528 641 926 691 828 865 68 97 136 121 404 372 657 157 255 253


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.6 4.9 4.7 4.4 4.8 4.0 4.0 4.2 – 3.8 3.8 4.1 6.2 6.3 6.1 4.6 4.7 5.5 5.9 6.9 6.9
Std Deviation (1e-4) 0.8 1.0 1.1 1.0 1.6 1.4 1.5 1.4 – 1.2 1.0 0.9 0.9 0.8 0.7 1.0 0.9 1.0 0.9 1.7 1.5
Intensity Change (Log2) – – – -0.09 0.03 -0.21 -0.21 -0.15 – -0.3 -0.31 -0.2 0.4 0.43 0.38 -0.04 0.02 0.23 0.34 0.57 0.57

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 – – 0
Bud 0 0 0 0 0 – 0 0 0 0 0 0 – – 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 – – 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 – – 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 – – 0
Cytoplasm 0 0 0.7 -0.9 -0.2 – -1.4 -2.4 -3.7 0 0 6.6 – – 7.0
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 – – 0
Endosome 0 0 0 0 0 – 0 0 0 0 2.8 2.3 – – 3.8
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 – – 0
Mitochondria 0 0 0 0 0 – 0 0 0 -6.3 -9.1 -14.6 – – -15.5
Nucleus 0 0 0 0 3.6 – 2.3 0 0 0 0 0 – – 0
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 – – 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 – – 0
Peroxisomes 0 0 0 0 0 – 0 0 0 -3.3 -3.9 -4.5 – – -2.0
SpindlePole 0 0 0 0 0 – 0 0 0 0 -0.8 -1.3 – – 2.3
Vacuole -2.1 0.9 1.0 0.8 0.6 – 0.6 -0.9 0.2 0 0 3.5 – – 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.5976 2.9206 3.1793 2.4242 1.882 2.9458 4.8701 3.8284 4.4931 4.7282 4.0336 4.3683 3.9 4.5191 4.0518 3.6921 3.841 3.9231
Actin 0.0251 0.0452 0.0176 0.0048 0.0016 0.0169 0.0493 0.0222 0.0211 0.0151 0.0175 0.0213 0.0132 0.0071 0.0126 0.0277 0.0318 0.0048
Bud 0.0015 0.0027 0.0011 0.0005 0.0002 0.0005 0.0012 0.0011 0.0004 0.0008 0.0002 0.0004 0.0003 0.0004 0.0003 0.0003 0.0006 0.0002
Bud Neck 0.0004 0.0016 0.001 0.0002 0.0001 0.0004 0.0037 0.0006 0.0008 0.0003 0.0002 0.0026 0.0008 0.0002 0.0009 0.0001 0.001 0.0003
Bud Periphery 0.0026 0.0039 0.0029 0.0011 0.0003 0.0014 0.0016 0.0013 0.002 0.0016 0.0004 0.0008 0.0007 0.0005 0.0005 0.0005 0.0008 0.0004
Bud Site 0.006 0.0392 0.0037 0.0004 0.0002 0.0006 0.0079 0.0072 0.002 0.0009 0.0007 0.0013 0.0007 0.0039 0.0094 0.0004 0.0015 0.0004
Cell Periphery 0.0013 0.0018 0.0015 0.0001 0.0001 0.0002 0.0008 0.0004 0.0163 0.0003 0.0001 0.0005 0.0004 0.0002 0.0002 0.0001 0.0002 0.0002
Cytoplasm 0.001 0.0049 0.002 0.0032 0.0002 0.0011 0.01 0.0009 0.014 0.0234 0.0003 0.0018 0.0005 0.0006 0.0003 0.0001 0.0011 0.0022
Cytoplasmic Foci 0.0182 0.0614 0.0094 0.0188 0.0089 0.0151 0.048 0.0549 0.0174 0.024 0.0105 0.0182 0.0198 0.0307 0.0111 0.0113 0.0302 0.0159
Eisosomes 0.0007 0.0012 0.0003 0.0001 0.0001 0.0004 0.0006 0.0002 0.0021 0.0002 0.0003 0.001 0.0006 0.0002 0.0004 0.0002 0.0004 0.0003
Endoplasmic Reticulum 0.0004 0.0016 0.0006 0.0004 0 0.0007 0.0032 0.0004 0.0059 0.0012 0.0001 0.0007 0.0018 0.0001 0.0001 0.0001 0.001 0.0006
Endosome 0.0448 0.0651 0.0384 0.0629 0.0089 0.043 0.1039 0.0827 0.0284 0.0361 0.0136 0.0234 0.0513 0.0378 0.0172 0.0092 0.0767 0.0395
Golgi 0.0595 0.0827 0.057 0.0808 0.009 0.0546 0.0675 0.0973 0.0417 0.0257 0.0404 0.0531 0.0903 0.0688 0.0355 0.0328 0.1306 0.0964
Lipid Particles 0.0264 0.0292 0.0049 0.0018 0.0019 0.0196 0.0346 0.0191 0.0116 0.0018 0.0069 0.028 0.0495 0.0153 0.0106 0.0285 0.0136 0.0203
Mitochondria 0.7497 0.5977 0.8102 0.8163 0.8584 0.81 0.4791 0.6022 0.7946 0.7232 0.8844 0.7577 0.6752 0.7664 0.8598 0.7738 0.6069 0.7276
None 0.0003 0.0054 0.0002 0.0002 0.0001 0.0003 0.0166 0.0006 0.0127 0.0007 0.0001 0.0021 0.0008 0.0004 0.0001 0.0001 0.0025 0.0101
Nuclear Periphery 0.0001 0.001 0.0004 0.0001 0 0.0007 0.0105 0.0006 0.0007 0.0001 0 0.001 0.0072 0.0001 0.0005 0 0.0032 0.0004
Nucleolus 0.0002 0.0052 0.0012 0.0001 0 0.0003 0.0023 0.0018 0.0002 0.0001 0.0001 0.0004 0.0004 0.0002 0.0002 0.0002 0.0002 0.0002
Nucleus 0.0002 0.0009 0.003 0.0001 0 0.0002 0.0067 0.0004 0.0006 0.0001 0.0001 0.0002 0.0004 0.0001 0.0001 0.0001 0.0003 0.0003
Peroxisomes 0.0549 0.0362 0.0248 0.0049 0.1083 0.0282 0.1275 0.0849 0.0237 0.1412 0.0232 0.0814 0.0775 0.0632 0.037 0.1127 0.0913 0.0762
Punctate Nuclear 0.0002 0.0019 0.0001 0 0 0.0004 0.0078 0.0005 0.0002 0.0001 0.0001 0.0002 0.0024 0.0002 0.0001 0 0.0015 0.0004
Vacuole 0.0031 0.0068 0.0155 0.0014 0.0005 0.0022 0.0117 0.0141 0.0016 0.002 0.0004 0.0019 0.002 0.002 0.001 0.0007 0.002 0.0013
Vacuole Periphery 0.0034 0.0045 0.0044 0.0018 0.0011 0.0034 0.0057 0.0066 0.0019 0.0011 0.0006 0.0022 0.0043 0.0015 0.002 0.0011 0.0027 0.0022

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.5457 6.5676 7.6148 12.8503 12.2046 12.8499 12.2435 10.2244 13.0867 16.1853
Translational Efficiency 0.4683 0.5748 0.4317 0.3191 0.3637 0.4688 0.3259 0.3177 0.272 0.2936

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✔
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
267 1236 235 1195 2171 2346 1459 1821 2438 3582 1694 3016

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 970.69 730.74 992.94 819.82 740.72 811.68 862.47 886.92 765.91 783.75 880.57 860.33
Standard Deviation 135.63 108.75 111.97 147.60 87.02 104.91 111.72 107.93 117.96 113.00 120.51 129.39
Intensity Change Log 2 — -0.409652 0.032696 -0.243703 — 0.131983 0.219546 0.259876 — -0.149990 0.116553 -0.003942

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.047204 0.001458 0.002169 0.036812 0.000943 0.000983 0.009272 0.005087 0.006009 0.001147 0.008286 0.017657
Bud Neck 0.009755 0.005580 0.015106 0.005265 0.002014 0.001935 0.003032 0.006458 0.002862 0.003193 0.004707 0.005985
Bud Site 0.086959 0.012080 0.020329 0.078258 0.002550 0.002452 0.027498 0.028216 0.011794 0.005775 0.026503 0.048043
Cell Periphery 0.002274 0.000375 0.000240 0.001176 0.000253 0.000167 0.000555 0.000389 0.000474 0.000239 0.000511 0.000701
Cytoplasm 0.026109 0.006126 0.004063 0.013878 0.002168 0.001197 0.006863 0.006591 0.004790 0.002898 0.006475 0.009478
Cytoplasmic Foci 0.140949 0.058904 0.121148 0.054411 0.036150 0.031561 0.023603 0.041797 0.047627 0.040996 0.037135 0.046795
Eisosomes 0.000575 0.000096 0.000108 0.000210 0.000095 0.000066 0.000094 0.000093 0.000148 0.000076 0.000096 0.000140
Endoplasmic Reticulum 0.003859 0.000384 0.004015 0.002646 0.000284 0.000107 0.000290 0.001009 0.000676 0.000203 0.000806 0.001658
Endosome 0.123815 0.109114 0.209498 0.075202 0.077840 0.081412 0.058338 0.111162 0.082875 0.090971 0.079308 0.096914
Golgi 0.198110 0.128145 0.105629 0.106982 0.125644 0.107508 0.052027 0.089759 0.133581 0.114629 0.059463 0.096583
Lipid Particles 0.002817 0.004093 0.019883 0.002215 0.003969 0.003684 0.000441 0.002261 0.003843 0.003825 0.003138 0.002243
Mitochondria 0.177441 0.566340 0.166036 0.477147 0.696008 0.714860 0.716983 0.577289 0.639217 0.663612 0.640553 0.537611
Mitotic Spindle 0.017110 0.019186 0.094282 0.035232 0.003567 0.004933 0.027360 0.029766 0.005050 0.009852 0.036644 0.031932
None 0.000184 0.000499 0.000257 0.000860 0.000161 0.000136 0.000171 0.000310 0.000163 0.000261 0.000183 0.000528
Nuclear Periphery 0.000184 0.000131 0.003799 0.000153 0.000059 0.000050 0.000053 0.000454 0.000072 0.000078 0.000572 0.000334
Nuclear Periphery Foci 0.000468 0.000202 0.005691 0.000409 0.000111 0.000078 0.000112 0.000538 0.000150 0.000121 0.000886 0.000487
Nucleolus 0.000244 0.000466 0.006438 0.000447 0.000322 0.000204 0.000080 0.000324 0.000314 0.000295 0.000962 0.000373
Nucleus 0.011984 0.000765 0.015940 0.002006 0.000554 0.000397 0.000121 0.000955 0.001806 0.000524 0.002315 0.001371
Peroxisomes 0.052916 0.063188 0.054992 0.056819 0.034297 0.033158 0.059158 0.032443 0.036336 0.043520 0.058580 0.042101
Vacuole 0.068362 0.012952 0.094423 0.030563 0.005026 0.006748 0.008676 0.043142 0.011963 0.008888 0.020571 0.038158
Vacuole Periphery 0.028684 0.009915 0.055953 0.019309 0.007984 0.008363 0.005274 0.021956 0.010251 0.008899 0.012305 0.020907

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 6.46 6.33 1.27 -9.95 -9.67 -0.20 -5.55 -5.31 -5.20 2.49 5.75 -1.54 -6.81 -10.92 -4.69
Bud Neck 1.92 -1.22 2.11 0.26 2.51 0.15 -1.91 -5.65 -5.96 -4.44 -0.59 -2.45 -4.81 -4.48 -1.63
Bud Site 7.98 6.64 0.78 -14.05 -10.04 0.24 -11.09 -12.84 -12.90 -0.27 4.65 -6.46 -14.65 -18.78 -7.28
Cell Periphery 3.63 3.91 2.06 -6.96 -8.84 2.19 -3.86 -2.88 -5.55 2.10 3.39 -0.45 -2.88 -9.00 -2.45
Cytoplasm 4.23 4.75 2.56 -4.55 -6.60 1.94 -5.44 -5.50 -7.47 0.04 2.48 -1.78 -5.00 -8.44 -3.35
Cytoplasmic Foci 8.65 1.57 9.18 1.35 7.75 2.43 6.19 -2.59 -4.82 -8.02 3.05 4.09 0.24 -3.12 -4.17
Eisosomes 5.04 4.82 3.81 -9.60 -6.33 2.31 0.10 0.12 -5.12 0.05 4.55 3.20 0.46 -10.97 -6.69
Endoplasmic Reticulum 5.98 -0.03 1.89 -6.47 1.61 2.88 -0.08 -4.13 -5.42 -4.23 5.34 -0.81 -5.12 -8.50 -4.22
Endosome 1.42 -5.93 5.19 6.26 11.09 -0.89 4.96 -7.08 -6.21 -11.23 -2.28 0.88 -3.75 -1.63 -4.31
Golgi 4.87 5.68 6.40 3.21 -0.20 3.52 15.50 6.90 3.70 -8.39 4.01 15.92 7.83 4.64 -9.33
Lipid Particles -0.85 -4.11 0.84 1.61 4.33 0.34 6.38 2.15 1.62 -3.72 0.06 0.88 2.43 2.27 1.22
Mitochondria -20.18 0.51 -15.18 6.14 -16.20 -2.00 -1.87 11.10 13.13 11.76 -2.66 -0.08 10.55 14.61 9.32
Mitotic Spindle -0.45 -6.17 -3.65 -4.64 4.87 -2.07 -10.34 -13.39 -12.40 -0.90 -5.06 -11.82 -15.73 -12.32 1.48
None -2.94 -1.44 -1.80 -0.90 -1.62 1.00 -0.39 -2.28 -2.79 -2.27 -2.44 -0.84 -2.40 -1.70 -2.30
Nuclear Periphery 1.13 -3.83 0.92 -0.55 3.91 0.75 0.53 -3.82 -3.91 -3.88 -0.06 -3.72 -4.05 -3.99 1.57
Nuclear Periphery Foci 1.80 -4.27 0.77 -3.02 4.46 1.42 -0.02 -4.41 -4.81 -4.34 1.27 -4.16 -4.78 -5.73 2.14
Nucleolus -1.54 -3.31 -0.65 0.06 3.19 0.54 1.13 -0.07 -1.47 -3.15 0.08 -2.16 -0.32 -0.65 2.13
Nucleus 2.52 -0.25 2.12 -2.22 2.60 0.49 1.66 -1.30 -1.95 -3.55 2.36 -0.29 0.46 -2.91 0.77
Peroxisomes -1.28 -0.30 -0.43 1.19 -0.06 0.37 -5.28 0.56 0.21 5.70 -2.42 -5.25 -1.86 0.52 3.95
Vacuole 6.45 -1.88 4.22 -7.75 6.73 -2.46 -4.07 -16.90 -15.88 -14.48 2.70 -4.33 -13.73 -17.69 -8.10
Vacuole Periphery 4.24 -3.64 2.01 -5.35 5.79 -0.58 4.00 -11.36 -10.86 -13.26 1.75 -1.65 -9.54 -11.74 -6.23
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein with a role in 5'-end processing of mitochondrial RNAs; located in the mitochondrial membrane
Localization
Cell Percentages mitochondrion (90%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Pet127

Pet127


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pet127-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available