Standard name
Human Ortholog
Description Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; null mutation suppresses cdc13-1 temperature sensitivity

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.88 0.94 0.93 0.96 0.92 0.96 0.96 0.93 0.98 0.88 0.92 0.96 0.95 0.98 0.91 0.91 0.86 0.44 0.48 0.41 0.48 0.31 0.29
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.07 0.06 0.1 0.05 0.05
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0.21 0.12 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.05 0.08 0.06 0 0.08 0 0 0 0 0 0 0.09 0.06 0 0.15 0.1 0.18 0.36 0.38 0.42 0.35 0.56 0.54
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 2 2 1 0 1 2 0 0 0 0 1 0 0 0 2 0 0 0
Bud 0 1 0 1 1 0 1 3 1 2 8 0 0 0 0 0 0 0 0 2 0 0 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 1 0 0 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 1 0 3 0 1 1 1 1 7 1 7 0 0 0 1 0 0 0 0 0 0 0 0
Cytoplasm 113 171 167 186 237 358 400 186 277 281 324 54 123 160 143 166 130 64 91 81 16 19 24
Endoplasmic Reticulum 4 7 6 4 2 2 1 3 2 1 3 1 1 1 4 6 2 5 3 7 0 0 0
Endosome 4 0 2 2 5 2 4 0 0 3 2 0 1 1 3 0 0 13 14 11 3 3 3
Golgi 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 2 0 0 0
Mitochondria 3 0 0 0 0 5 8 9 11 66 41 0 0 0 1 0 0 2 0 4 1 0 1
Nucleus 0 0 3 0 3 3 1 1 4 0 3 0 2 0 0 0 3 0 0 0 0 0 1
Nuclear Periphery 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0
Nucleolus 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 6 14 10 7 21 12 17 6 4 10 8 5 8 5 23 19 27 52 73 83 11 33 44
Unique Cell Count 129 182 180 194 259 372 418 201 284 320 353 56 129 163 158 183 151 146 192 200 34 61 83
Labelled Cell Count 132 193 192 200 270 385 437 210 306 366 399 60 135 167 175 192 164 146 192 200 34 61 83


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.0 8.7 7.5 7.4 7.9 6.4 6.5 5.5 5.8 5.1 5.5 7.9 7.6 7.8 10.2 11.3 10.6 8.0 8.6
Std Deviation (1e-4) 0.7 1.2 0.9 1.2 1.5 1.1 1.4 1.1 1.1 0.9 0.9 1.3 1.1 1.1 1.7 2.1 2.7 2.0 1.7
Intensity Change (Log2) -0.02 0.07 -0.24 -0.21 -0.46 -0.37 -0.57 -0.47 0.07 0.01 0.04 0.43 0.58 0.49 0.09 0.18

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.3 -0.5 1.8 1.5 -0.1 2.5 -1.7 -0.4 1.0 0.9 2.4 -0.8 -0.7 -2.0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 6.5 4.8 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -0.9 1.0 -1.3 -0.8 -1.2 -2.5 -1.3 -2.0 0 0.2 -1.1 2.8 1.7 3.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.5369 3.1527 2.7898 2.2889 2.5593 2.729 2.0392 2.8905 2.2689 2.3506 1.9923 2.4106 2.4567 2.9426 2.7463 2.5945 2.3272 2.5777
Actin 0.0155 0.0002 0.0123 0.0273 0.0362 0.0048 0.0161 0 0.004 0.0866 0.021 0.0016 0.0253 0.0001 0.0031 0.0438 0.0138 0.0036
Bud 0.0005 0.0012 0.0008 0.0054 0.0035 0.0011 0.0008 0.0003 0.001 0.0018 0.0026 0.0005 0.0004 0.0008 0.0008 0.0157 0.0004 0.001
Bud Neck 0.0021 0.0003 0.0021 0.0064 0.0016 0.0061 0.0133 0.0002 0.0008 0.002 0.0006 0.0021 0.001 0.0011 0.0006 0.0012 0.0018 0.0011
Bud Periphery 0.0006 0.0008 0.0007 0.0038 0.0032 0.0012 0.001 0.0003 0.0008 0.0033 0.0078 0.0003 0.0004 0.0003 0.0005 0.0068 0.0006 0.0005
Bud Site 0.0022 0.0019 0.0045 0.0161 0.056 0.0008 0.0094 0.0013 0.0091 0.0057 0.0036 0.0005 0.0022 0.006 0.0022 0.0072 0.0017 0.0018
Cell Periphery 0.0004 0.0002 0.0002 0.0002 0.0004 0.0001 0.0006 0.0002 0.0003 0.0005 0.0005 0.0001 0.0002 0.0003 0.0002 0.0002 0.0002 0.0001
Cytoplasm 0.5807 0.7636 0.6782 0.4884 0.4859 0.7053 0.4792 0.6687 0.6203 0.5034 0.5526 0.7392 0.6446 0.8026 0.7196 0.5439 0.6365 0.8051
Cytoplasmic Foci 0.0405 0.0235 0.0377 0.0635 0.0192 0.0428 0.0641 0.0396 0.0367 0.0696 0.0355 0.0305 0.0244 0.0164 0.0197 0.0349 0.0535 0.0189
Eisosomes 0.0002 0 0.0001 0.0003 0.0002 0.0001 0.0002 0 0.0001 0.0002 0.0005 0 0.0002 0 0 0.0002 0.0002 0
Endoplasmic Reticulum 0.0154 0.0134 0.0092 0.008 0.0046 0.0105 0.0221 0.0083 0.0123 0.0066 0.0058 0.0123 0.023 0.0292 0.0104 0.0056 0.009 0.0141
Endosome 0.103 0.0799 0.0998 0.1353 0.1046 0.0986 0.1347 0.1111 0.13 0.184 0.1694 0.1036 0.0884 0.0426 0.0905 0.1094 0.1091 0.0735
Golgi 0.0082 0.0015 0.0051 0.0174 0.0173 0.0024 0.0105 0.0015 0.003 0.0055 0.0108 0.0054 0.0064 0.0005 0.0012 0.0049 0.0116 0.001
Lipid Particles 0.0139 0.0004 0.0039 0.0086 0.0087 0.0005 0.0111 0.0015 0.0081 0.0011 0.0162 0.0028 0.0067 0.0004 0.0007 0.0027 0.0341 0.0009
Mitochondria 0.0068 0.0006 0.0125 0.0136 0.007 0.004 0.0041 0.001 0.0022 0.0038 0.0472 0.0023 0.0022 0.0003 0.0004 0.0021 0.0036 0.0005
None 0.0984 0.0432 0.0606 0.0608 0.0808 0.063 0.1003 0.1088 0.0573 0.0738 0.013 0.0269 0.0341 0.0157 0.0302 0.0657 0.0224 0.0098
Nuclear Periphery 0.0091 0.0074 0.0057 0.0063 0.0112 0.0054 0.0091 0.0025 0.0037 0.0023 0.0047 0.0044 0.0193 0.0084 0.0055 0.0031 0.0083 0.0042
Nucleolus 0.0006 0.0001 0.0005 0.0007 0.0004 0.0002 0.0012 0.0005 0.0008 0.0002 0.0003 0.0001 0.0006 0.0002 0.0002 0.0002 0.0009 0.0001
Nucleus 0.0069 0.0057 0.0056 0.0053 0.0092 0.0047 0.0037 0.0026 0.0038 0.0022 0.0024 0.0037 0.0078 0.0034 0.0037 0.0028 0.0043 0.0036
Peroxisomes 0.0157 0.0001 0.0069 0.0147 0.004 0.0014 0.0091 0.0001 0.01 0.0011 0.0107 0.0018 0.0077 0.0001 0.0004 0.0029 0.0179 0.0072
Punctate Nuclear 0.0041 0.0006 0.0028 0.0066 0.0149 0.0013 0.0059 0.0007 0.0016 0.0006 0.0006 0.0008 0.0062 0.0006 0.001 0.0009 0.0127 0.0006
Vacuole 0.0696 0.0491 0.0447 0.0985 0.1137 0.0383 0.0942 0.0438 0.0816 0.0392 0.0769 0.0497 0.0926 0.0675 0.0978 0.1321 0.0506 0.044
Vacuole Periphery 0.0057 0.0065 0.0062 0.013 0.0174 0.0074 0.0095 0.007 0.0127 0.0067 0.0172 0.0115 0.0064 0.0034 0.0112 0.0137 0.0067 0.0085

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.3319 5.7886 8.1612 16.0565 15.5319 12.2964 14.0468 17.9737 13.1969 16.6623
Translational Efficiency 0.9357 1.2267 1.105 0.5281 0.6429 0.9184 0.5432 0.5169 0.7231 0.7549

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1318 1369 875 496 2121 1956 261 1196 3439 3325 1136 1692

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 689.52 838.02 1117.41 1046.57 812.30 849.60 1223.31 1034.04 765.24 844.83 1141.74 1037.71
Standard Deviation 78.88 112.38 136.10 162.13 100.76 119.03 154.50 137.58 110.50 116.48 147.44 145.32
Intensity Change Log 2 0.281392 0.696494 0.602005 0.064771 0.590705 0.348207 0.168278 0.640240 0.470295

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000146 0.000201 0.000245 0.003123 0.000061 0.000321 0.000175 0.000376 0.000093 0.000272 0.000229 0.001181
Bud Neck 0.023333 0.008060 0.002161 0.006428 0.007679 0.010991 0.004416 0.006880 0.013679 0.009784 0.002679 0.006747
Bud Site 0.014866 0.015889 0.006868 0.032672 0.005819 0.020364 0.004680 0.027232 0.009286 0.018521 0.006365 0.028827
Cell Periphery 0.000321 0.000077 0.000080 0.000332 0.000059 0.000122 0.000079 0.000065 0.000159 0.000103 0.000080 0.000143
Cytoplasm 0.379683 0.308015 0.704347 0.355012 0.383501 0.211858 0.206435 0.378669 0.382037 0.251449 0.589950 0.371734
Cytoplasmic Foci 0.267248 0.206746 0.033788 0.068251 0.161078 0.198377 0.022929 0.047527 0.201768 0.201823 0.031293 0.053602
Eisosomes 0.000296 0.000040 0.000011 0.000028 0.000038 0.000060 0.000026 0.000014 0.000137 0.000052 0.000015 0.000018
Endoplasmic Reticulum 0.008796 0.003107 0.001759 0.002951 0.004197 0.006063 0.004274 0.000584 0.005959 0.004846 0.002337 0.001278
Endosome 0.058082 0.097176 0.006685 0.026118 0.057054 0.118811 0.021474 0.025555 0.057448 0.109903 0.010083 0.025720
Golgi 0.008255 0.005372 0.000331 0.010941 0.002214 0.010199 0.000286 0.003893 0.004529 0.008212 0.000320 0.005959
Lipid Particles 0.017199 0.005091 0.001731 0.002379 0.005438 0.007613 0.002101 0.001361 0.009945 0.006575 0.001816 0.001660
Mitochondria 0.008715 0.002936 0.000131 0.004488 0.001074 0.005431 0.000117 0.001484 0.004002 0.004404 0.000128 0.002364
Mitotic Spindle 0.000317 0.002915 0.005505 0.018301 0.000437 0.005284 0.000606 0.009286 0.000391 0.004309 0.004380 0.011929
None 0.001604 0.000306 0.001511 0.001716 0.000285 0.000832 0.000355 0.001810 0.000790 0.000616 0.001245 0.001782
Nuclear Periphery 0.000474 0.000591 0.000982 0.000222 0.000391 0.000286 0.001365 0.000258 0.000423 0.000412 0.001070 0.000248
Nuclear Periphery Foci 0.000736 0.001098 0.007799 0.002422 0.000618 0.000644 0.003511 0.001463 0.000663 0.000831 0.006814 0.001744
Nucleolus 0.001264 0.000865 0.000301 0.000436 0.000760 0.001231 0.000929 0.000448 0.000953 0.001080 0.000446 0.000444
Nucleus 0.033165 0.012507 0.083346 0.013983 0.020842 0.009874 0.079023 0.011227 0.025565 0.010958 0.082353 0.012035
Peroxisomes 0.003474 0.003623 0.000215 0.004020 0.001520 0.002913 0.000705 0.002217 0.002269 0.003206 0.000327 0.002746
Vacuole 0.163275 0.313418 0.141428 0.441093 0.341066 0.364029 0.641873 0.474749 0.272927 0.343191 0.256407 0.464883
Vacuole Periphery 0.008751 0.011966 0.000775 0.005083 0.005871 0.024697 0.004641 0.004903 0.006975 0.019455 0.001663 0.004956

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.34 -4.78 -2.02 -1.95 -1.83 -3.94 -5.74 -3.20 0.48 -1.22 -4.21 -7.85 -2.60 -1.80 -1.83
Bud Neck 10.26 14.73 12.04 3.01 -4.61 -3.76 3.99 1.92 5.12 -2.07 4.87 15.77 10.17 5.65 -5.86
Bud Site -0.43 4.22 -3.20 -2.98 -5.73 -10.19 1.09 -7.80 0.21 -7.79 -7.92 2.53 -7.43 -1.70 -8.40
Cell Periphery 10.30 10.34 1.99 -1.79 -1.55 -4.21 -2.51 1.35 4.51 3.00 4.29 6.44 3.29 0.52 -0.12
Cytoplasm 7.29 -24.36 1.01 -3.79 17.89 22.91 9.93 0.46 -17.84 -9.10 21.69 -16.22 0.88 -15.41 14.99
Cytoplasmic Foci 8.87 43.89 34.45 24.98 -5.70 -7.15 33.09 31.06 34.31 -5.97 0.04 51.77 45.74 43.37 -6.90
Eisosomes 15.92 17.66 16.96 5.07 -2.39 -4.07 3.46 13.38 8.71 4.75 11.57 18.09 18.31 10.53 1.45
Endoplasmic Reticulum 5.10 6.33 5.66 1.99 0.40 -2.66 0.24 8.30 9.54 8.15 1.77 6.83 9.56 9.66 6.15
Endosome -9.11 21.53 14.47 21.06 -5.50 -18.31 12.49 18.87 32.61 0.59 -19.86 30.45 23.83 38.52 -6.91
Golgi 4.15 15.28 1.41 0.06 -2.21 -9.94 12.51 0.13 6.93 -2.10 -6.48 18.71 1.70 5.07 -3.03
Lipid Particles 11.28 15.01 14.59 5.52 -1.19 -4.23 10.32 15.74 12.76 2.86 6.27 17.70 19.15 14.11 2.30
Mitochondria 3.85 6.34 3.89 0.60 -1.91 -5.39 4.37 0.67 5.55 -2.52 -0.49 7.16 4.31 4.87 -2.93
Mitotic Spindle -2.61 -4.52 -3.09 -2.09 -1.27 -4.05 -1.37 -4.25 -0.66 -3.92 -4.81 -4.53 -5.20 -2.01 -1.61
None 4.04 0.98 0.83 -1.34 0.37 -1.98 -1.08 -0.96 -0.26 -0.80 1.03 -1.95 -0.40 -0.75 0.11
Nuclear Periphery -0.45 -5.97 1.37 1.11 9.18 2.03 -7.83 -0.44 -2.86 7.76 0.12 -9.52 0.56 0.18 10.66
Nuclear Periphery Foci -1.91 -11.36 -6.79 -5.35 8.23 -0.23 -8.04 -4.80 -4.07 5.07 -1.59 -12.74 -7.34 -5.80 10.05
Nucleolus 1.38 4.04 3.75 2.22 -1.00 -1.11 0.07 1.74 2.58 3.23 -0.25 3.66 3.58 3.24 -0.40
Nucleus 12.31 -15.96 4.85 -3.34 17.74 10.50 -6.93 4.43 -5.99 7.49 15.94 -18.95 7.36 -6.38 21.20
Peroxisomes -0.10 10.18 1.59 1.45 -3.94 -6.37 4.88 0.16 2.89 -1.69 -3.27 13.76 1.37 3.27 -3.89
Vacuole -19.24 -3.23 -21.91 -10.83 -18.41 -2.76 -15.10 -16.44 -13.22 6.28 -11.91 -1.78 -27.45 -17.88 -17.82
Vacuole Periphery -3.15 14.71 5.47 7.34 -2.06 -18.82 3.46 5.32 20.28 1.34 -17.46 18.55 7.98 20.91 -3.25
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; null mutation suppresses cdc13-1 temperature sensitivity
Localization
Cell Percentages cytoplasm (79%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Rtc5

Rtc5


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rtc5-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available