Standard name
Human Ortholog
Description Broad-specificity lysophospholipid acyltransferase; part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.07 0.07 0.07 0.06 0.07 0 – 0 0 0 0 0 0 0 0 0.13 0.09 0.1 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.09 0.11 0.12 0.18 0.13 0.11 – 0 0.09 0.08 0.07 0.09 0.2 0.25 0.21 0.41 0.39 0.47 0 0 0.05 0.05 0 0.07
Cytoplasm 0.1 0.2 0.15 0.26 0.22 0.23 – 0.28 0.4 0.27 0.3 0.26 0.15 0.17 0.24 0.32 0.34 0.24 0 0.06 0 0 0 0
Endoplasmic Reticulum 0.84 0.79 0.75 0.6 0.44 0.51 – 0.31 0.2 0.33 0.25 0.24 0.73 0.72 0.68 0 0 0 0.9 0.8 0.84 0.8 0.8 0.77
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0
Mitochondria 0 0 0.07 0.18 0.18 0.36 – 0.28 0.36 0.41 0.47 0.52 0 0 0 0.09 0.12 0.07 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0.05 0 0.19 0.08 – 0.26 0.18 0.13 0.14 0.12 0 0 0 0.18 0.11 0.11 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 28 16 26 16 26 19 – 19 7 16 8 17 12 7 10 37 22 19 8 10 12 6 7 7
Bud 6 3 4 1 8 11 – 14 16 11 29 19 2 3 1 7 7 1 1 1 0 1 1 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 1 3 4 0 1 1
Bud Site 0 0 0 0 0 0 – 0 1 1 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 37 25 42 51 51 45 – 21 33 33 29 48 66 86 81 115 91 90 8 4 19 7 8 11
Cytoplasm 41 44 53 72 84 99 – 170 146 117 131 137 51 57 94 90 80 46 6 14 7 2 3 3
Endoplasmic Reticulum 361 176 262 168 167 218 – 187 73 144 109 128 243 250 266 3 3 3 427 201 324 128 164 128
Endosome 0 0 2 1 15 3 – 11 7 3 2 4 1 0 0 1 2 0 1 0 3 1 1 0
Golgi 2 0 2 0 2 0 – 0 0 0 0 0 0 0 0 5 1 15 2 2 1 0 2 1
Mitochondria 4 7 24 51 69 156 – 169 132 178 205 277 0 0 0 25 28 13 6 3 7 5 7 5
Nucleus 0 0 3 0 0 1 – 2 3 1 4 2 3 0 2 3 5 6 0 0 0 0 0 0
Nuclear Periphery 0 0 4 0 3 1 – 6 1 10 5 9 0 0 0 1 1 2 0 1 0 1 0 0
Nucleolus 0 0 0 0 0 1 – 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 1 0 0 0 – 0 0 0 0 0 0 0 1 2 0 1 0 0 0 0 0 0
Vac/Vac Membrane 13 3 19 12 73 33 – 157 67 56 60 62 2 10 8 51 27 22 5 5 4 2 5 5
Unique Cell Count 428 224 350 278 380 428 613 369 431 440 531 331 345 394 278 235 192 476 253 387 160 205 167
Labelled Cell Count 492 274 442 372 498 587 758 487 570 583 703 380 413 463 340 267 218 476 253 387 160 205 167


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.2 9.2 7.2 7.3 7.7 6.7 – 6.9 6.5 6.1 6.0 5.8 9.4 9.6 9.6 8.8 10.4 12.1 9.7 10.2 10.8
Std Deviation (1e-4) 1.1 1.4 1.0 1.3 1.2 1.3 – 1.4 1.5 1.1 1.2 1.1 1.1 1.0 1.1 1.5 1.8 2.0 1.3 1.6 1.4
Intensity Change (Log2) – – – 0.03 0.1 -0.09 – -0.06 -0.15 -0.23 -0.27 -0.31 0.39 0.43 0.42 0.3 0.54 0.76 0.45 0.51 0.59


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.8 -0.3 -1.8 – -3.1 -3.5 -2.3 -3.9 -2.8 -2.2 -3.3 -3.1 2.4 0.8 1.0
Bud 0 1.0 1.4 – 1.3 2.6 1.4 3.8 2.2 0 0 0 0 0 0
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 2.2 0.6 -0.7 – -5.2 -1.3 -2.0 -2.6 -1.4 2.8 4.4 3.1 8.4 7.6 9.0
Cytoplasm 3.4 2.4 2.8 – 4.5 7.3 4.0 4.8 3.8 0.1 0.5 3.0 5.1 5.3 2.5
Endoplasmic Reticulum -3.9 -8.5 -6.8 – -13.3 -14.8 -11.5 -14.0 -14.8 -0.4 -0.7 -2.2 -18.6 -17.5 -16.3
Endosome 0 3.0 0 – 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 0 0 4.6
Mitochondria 4.4 4.6 9.7 – 7.7 9.4 10.9 12.2 13.9 -4.9 -5.0 -5.3 1.0 2.1 0
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 – 0 0 1.2 0 0.7 0 0 0 0 0 0
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vacuole -0.6 5.6 1.3 – 7.8 5.3 3.6 3.8 3.1 -3.6 -1.7 -2.5 5.1 2.7 2.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.0549 7.3828 7.3157 6.7022 7.383 7.2494 8.3831 8.3804 8.7721 8.2556 8.1133 8.6907 8.2346 7.8759 8.2422 7.7959 8.8305 8.01
Actin 0.0037 0.009 0.0185 0.004 0.0739 0.0013 0.0218 0.0012 0.0105 0.0014 0.003 0.0029 0.0088 0.0049 0.005 0.0059 0.0112 0.0042
Bud 0.0002 0.0019 0.0047 0.0036 0.0006 0.0001 0.0002 0.0002 0.0015 0.0001 0.0004 0.0003 0.0011 0.0077 0.001 0.0067 0.0013 0.0009
Bud Neck 0.0036 0.0033 0.0015 0.0022 0.0077 0.005 0.0006 0.0009 0.002 0.0008 0.0004 0.006 0.0007 0.0014 0.0074 0.0005 0.0015 0.0084
Bud Periphery 0.0007 0.0016 0.0047 0.0031 0.0019 0.0006 0.0008 0.0018 0.0077 0.0032 0.0019 0.0019 0.0061 0.0226 0.0072 0.0333 0.0103 0.0069
Bud Site 0.0065 0.032 0.0082 0.0053 0.0007 0.0006 0.0005 0.0073 0.0042 0.0001 0.0004 0.0001 0.0007 0.013 0.0006 0.0006 0.0008 0.0011
Cell Periphery 0.0104 0.0091 0.0178 0.0064 0.0018 0.0043 0.01 0.0156 0.0127 0.0115 0.0017 0.0037 0.0035 0.0172 0.0083 0.0042 0.0031 0.0075
Cytoplasm 0.1017 0.2694 0.1186 0.1307 0.0554 0.0888 0.0432 0.1388 0.1166 0.0389 0.0803 0.0831 0.0661 0.174 0.1123 0.0753 0.0923 0.1412
Cytoplasmic Foci 0.0038 0.007 0.0083 0.0022 0.0044 0.0032 0.0054 0.0032 0.008 0.0005 0.0062 0.0029 0.0039 0.0103 0.0053 0.0198 0.0053 0.007
Eisosomes 0.0003 0.0002 0.0003 0.0001 0.0009 0.0001 0.0036 0.0002 0.0005 0.0002 0.0003 0.0002 0.0003 0.0002 0.0004 0.0024 0.0003 0.0001
Endoplasmic Reticulum 0.7894 0.573 0.7317 0.7664 0.7037 0.8488 0.8208 0.7558 0.7922 0.927 0.7139 0.8653 0.7479 0.6104 0.7308 0.6592 0.7677 0.6756
Endosome 0.0094 0.0162 0.0236 0.0041 0.0833 0.0097 0.0171 0.0073 0.0049 0.0018 0.0465 0.0041 0.018 0.0046 0.0118 0.0297 0.0179 0.0108
Golgi 0.0019 0.0047 0.0066 0.0012 0.0174 0.002 0.0117 0.0021 0.006 0.0009 0.0125 0.0029 0.005 0.003 0.0031 0.0132 0.0089 0.0036
Lipid Particles 0.0087 0.0064 0.0151 0.0014 0.0075 0.0082 0.0197 0.0193 0.0118 0.0062 0.0163 0.0027 0.0059 0.0077 0.0061 0.0152 0.0041 0.0033
Mitochondria 0.0029 0.002 0.0011 0.0026 0.0042 0.0011 0.0031 0.0009 0.0096 0.0003 0.0185 0.0006 0.0031 0.0013 0.0011 0.0234 0.0165 0.0013
None 0.0238 0.0145 0.0039 0.0076 0.0017 0.0119 0.0244 0.0284 0.0029 0.0003 0.0565 0.0158 0.1066 0.1031 0.0801 0.0823 0.0448 0.1123
Nuclear Periphery 0.013 0.0161 0.0148 0.0126 0.0212 0.0051 0.0073 0.0069 0.0036 0.0036 0.0176 0.0048 0.01 0.0059 0.006 0.0045 0.0068 0.0034
Nucleolus 0.0003 0.001 0.0003 0.0013 0.0002 0.0001 0.0001 0.0004 0.0001 0 0.0005 0 0.0002 0.0002 0.0002 0.0003 0.0001 0.0003
Nucleus 0.0055 0.0089 0.0032 0.0193 0.0019 0.0015 0.0007 0.0015 0.0007 0.0003 0.0106 0.0005 0.0015 0.002 0.0013 0.0013 0.0012 0.0014
Peroxisomes 0.0003 0.0002 0.0002 0.0001 0.0005 0.0001 0.0019 0.0001 0.0004 0 0.0004 0.0001 0.0009 0.0003 0.0003 0.0134 0.0005 0.0029
Punctate Nuclear 0.0032 0.0118 0.002 0.017 0.0013 0.0002 0.0017 0.0006 0.0003 0 0.0049 0.0001 0.0005 0.0004 0.0038 0.0007 0.0003 0.0016
Vacuole 0.0096 0.0109 0.0139 0.008 0.0073 0.0068 0.0048 0.0072 0.0037 0.0026 0.0051 0.0017 0.0074 0.0086 0.0068 0.0062 0.0043 0.0056
Vacuole Periphery 0.0009 0.0009 0.0011 0.0009 0.0025 0.0005 0.0007 0.0003 0.0002 0.0002 0.002 0.0003 0.0018 0.0011 0.0011 0.0019 0.0011 0.0006

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 57.8397 32.3489 19.2821 30.1391 35.3807 36.7598 37.5337 39.4467 32.8698 42.1361
Translational Efficiency 0.6315 0.841 0.9949 0.6079 0.68 0.9214 0.7658 0.5008 0.5983 0.6386

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
109 1340 583 1447 2516 1574 950 1456 2625 2914 1533 2903

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1017.18 963.66 1198.60 1186.10 900.17 993.22 1187.66 1212.69 905.03 979.63 1191.82 1199.44
Standard Deviation 131.93 150.08 151.90 171.83 116.10 147.49 161.98 179.95 119.11 149.42 158.31 176.46
Intensity Change Log 2 — -0.077979 0.236775 0.221651 — 0.141916 0.399852 0.429941 — 0.029442 0.315638 0.323193

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.010374 0.002456 0.005956 0.014399 0.001162 0.002758 0.007537 0.009628 0.001545 0.002619 0.006935 0.012006
Bud Neck 0.019691 0.002964 0.006338 0.009199 0.001403 0.003483 0.007248 0.006442 0.002163 0.003244 0.006902 0.007816
Bud Site 0.041653 0.020222 0.027897 0.062782 0.006910 0.014901 0.030795 0.039213 0.008353 0.017348 0.029693 0.050961
Cell Periphery 0.003394 0.011288 0.014447 0.044895 0.010488 0.012645 0.008088 0.051588 0.010194 0.012021 0.010506 0.048252
Cytoplasm 0.142529* 0.099523 0.056151 0.102989* 0.153972* 0.105636* 0.092179 0.068730 0.153497* 0.102825* 0.078478 0.085806
Cytoplasmic Foci 0.098260 0.035017 0.009448 0.019987 0.015883 0.018667 0.007491 0.010781 0.019303 0.026185 0.008235 0.015370
Eisosomes 0.001379 0.001039 0.000984 0.002876 0.001576 0.001533 0.001139 0.003235 0.001568 0.001306 0.001080 0.003056
Endoplasmic Reticulum 0.171843* 0.746057* 0.789701* 0.580919* 0.729151* 0.764475* 0.764490* 0.704765* 0.706009* 0.756006* 0.774078* 0.643034*
Endosome 0.027665 0.009445 0.008679 0.010777 0.003153 0.006040 0.007900 0.007669 0.004171 0.007606 0.008197 0.009219
Golgi 0.011914 0.016390 0.002737 0.008322 0.009875 0.015929 0.004074 0.008097 0.009959 0.016141 0.003566 0.008209
Lipid Particles 0.030626 0.017967 0.021545 0.063001 0.015092 0.017221 0.020472 0.048948 0.015737 0.017564 0.020880 0.055953
Mitochondria 0.010943 0.008340 0.000266 0.002401 0.011762 0.008697 0.001272 0.003563 0.011728 0.008533 0.000889 0.002984
Mitotic Spindle 0.004103 0.000535 0.000264 0.006295 0.000110 0.000356 0.000616 0.001198 0.000276 0.000438 0.000482 0.003739
None 0.000071 0.003576 0.000173 0.000949 0.010749 0.003545 0.002591 0.001164 0.010306 0.003559 0.001671 0.001057
Nuclear Periphery 0.001267 0.000333 0.000687 0.000853 0.000233 0.000637 0.000792 0.000353 0.000276 0.000497 0.000752 0.000602
Nuclear Periphery Foci 0.014809 0.003424 0.019139 0.009965 0.000956 0.001978 0.011336 0.002276 0.001531 0.002643 0.014304 0.006108
Nucleolus 0.000162 0.000150 0.000027 0.000102 0.000078 0.000155 0.000050 0.000065 0.000081 0.000153 0.000041 0.000083
Nucleus 0.028370 0.002728 0.004438 0.007389 0.002884 0.002763 0.008183 0.003512 0.003943 0.002747 0.006759 0.005445
Peroxisomes 0.002982 0.007254 0.000491 0.006913 0.020400 0.011496 0.000904 0.012942 0.019676 0.009546 0.000747 0.009937
Vacuole 0.374812* 0.007892 0.030442 0.043581 0.002600 0.004688 0.022113 0.013557 0.018056 0.006161 0.025280 0.028522
Vacuole Periphery 0.003153 0.003401 0.000191 0.001406 0.001563 0.002396 0.000732 0.002273 0.001629 0.002859 0.000526 0.001841

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.65 0.74 -1.22 -8.23 -4.74 -2.69 -5.37 -6.93 -5.37 -1.25 -2.37 -6.19 -10.76 -9.67 -4.07
Bud Neck 1.89 1.44 1.06 -7.24 -2.59 -3.72 -5.00 -7.28 -3.54 0.70 -2.12 -5.46 -9.72 -7.68 -0.99
Bud Site 1.88 1.01 -2.34 -9.36 -5.94 -4.29 -6.83 -9.77 -6.77 -1.68 -5.69 -7.68 -15.60 -11.61 -5.63
Cell Periphery -6.04 -4.59 -14.61 -10.96 -8.10 -1.73 2.38 -14.74 -13.27 -15.31 -1.86 -0.26 -18.70 -17.11 -17.01
Cytoplasm 2.62 4.89 2.25 -1.07 -7.36 9.37 9.55 17.41 7.10 3.87 11.64 14.55 14.89 3.86 -1.65
Cytoplasmic Foci 6.07 8.73 7.57 4.64 -5.35 -1.57 5.75 3.18 4.20 -2.01 -3.88 7.62 2.10 5.93 -5.88
Eisosomes 0.83 0.91 -4.83 -6.59 -6.12 0.17 1.86 -4.31 -4.33 -5.55 1.26 2.34 -5.46 -7.15 -8.08
Endoplasmic Reticulum -21.35* -21.62 -14.69 13.75 13.71 -3.81 -2.59 2.48 5.32 4.15 -6.30 -6.52 7.81 13.81 12.90
Endosome 3.59 3.73 3.18 -1.69 -2.20 -5.11 -6.53 -5.66 -1.77 0.36 -6.96 -7.16 -8.86 -2.65 -1.41
Golgi -1.36 1.57 0.38 4.82 -4.60 -4.13 6.88 1.39 4.40 -3.06 -5.70 9.00 1.79 6.47 -5.04
Lipid Particles 1.84 0.91 -6.01 -12.47 -9.33 -1.67 -2.53 -11.15 -10.13 -7.55 -1.76 -3.10 -17.21 -16.08 -12.18
Mitochondria 0.13 1.65 1.26 5.44 -8.56 2.53 14.05 8.82 4.60 -3.84 3.03 14.53 10.88 7.14 -6.33
Mitotic Spindle 1.06 1.16 -1.13 -4.78 -5.05 -1.34 -2.17 -2.04 -1.48 -1.01 -1.06 -1.29 -5.28 -4.97 -4.90
None -3.85 -2.02 -2.10 2.63 -1.83 5.62 5.93 8.84 3.04 1.50 5.81 7.52 8.92 3.99 0.99
Nuclear Periphery 2.12 1.16 0.57 -3.71 -1.33 -1.38 -3.83 -2.68 0.98 3.12 -1.35 -4.63 -4.70 -0.77 1.11
Nuclear Periphery Foci 5.09 -1.82 1.40 -5.48 3.38 -2.65 -6.70 -5.17 -0.77 5.81 -2.59 -9.92 -8.56 -5.60 5.59
Nucleolus -0.09 3.44 1.27 0.63 -5.78 -0.98 2.37 0.96 1.10 -1.05 -1.32 4.54 -0.64 1.22 -4.34
Nucleus 4.20 3.86 3.24 -6.56 -3.39 0.31 -6.04 -1.30 -1.39 4.57 3.05 -4.42 -3.57 -6.11 1.33
Peroxisomes -5.02 4.77 -5.07 0.48 -9.97 6.04 17.10 4.89 -1.01 -11.59 8.09 17.32 7.87 -0.36 -14.91
Vacuole 14.05 13.13 12.51 -12.56 -3.80 -3.66 -9.82 -10.08 -7.53 4.10 6.55 -2.50 -4.59 -14.20 -2.07
Vacuole Periphery -0.42 1.36 0.68 3.94 -3.56 -1.58 2.76 -1.43 0.19 -2.85 -3.44 4.71 -0.68 2.36 -3.93
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Broad-specificity lysophospholipid acyltransferase; part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids
Localization
Cell Percentages ER (97%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Ale1

Ale1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ale1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available