Standard name
Human Ortholog
Description Component of mRNP complexes associated with polyribosomes; involved in localization of mRNAs to P bodies; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.06 0 0.05 0.29 0.11 0.18 0.1 0.1 0.08 0.16 0.15 0.21 0 0 0 0 0 0 0 0 0.06 0.07 0.09 0.06
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.05 0 0 0.16 0 0.05 0 0.08 0.05 0.08 0.18 0.22 0.15 0.1 0.22 0.26 0.22 0 0 0 0 0.05 0
Cytoplasm 0.3 0.23 0.1 0 0.11 0.06 0.11 0.13 0.06 0.07 0.08 0.18 0.15 0.42 0.66 0.58 0.57 0.64 0.06 0.07 0 0 0 0.08
Endoplasmic Reticulum 0.7 0.78 0.85 0.53 0.37 0.61 0.65 0.68 0.69 0.72 0.54 0.51 0.69 0.55 0.35 0 0 0 0.82 0.85 0.73 0.79 0.72 0.65
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0.05 0 0.15 0.5 0.58 0.29 0.22 0.15 0.08 0.08 0.23 0.1 0 0 0 0.27 0.27 0.15 0 0 0.08 0.05 0.06 0.1
Mitochondria 0 0 0 0.38 0.21 0.37 0.17 0.14 0.28 0.38 0.27 0.36 0 0 0 0.06 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 10 3 1 10 2 9 11 14 3 12 7 8 9 3 1 2 0 1 8 1 3 11 27 16
Bud 3 1 0 0 0 1 3 1 1 1 0 1 4 0 0 1 0 2 1 0 0 0 4 5
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 5 0 0 3 0 5 3 3 4 4 7 45 49 34 43 46 37 1 0 0 5 13 3
Cytoplasm 52 25 2 1 2 3 12 18 2 5 4 7 31 137 224 114 101 107 12 8 0 4 9 20
Endoplasmic Reticulum 121 84 17 18 7 31 71 94 25 55 26 20 143 181 119 8 6 6 165 99 44 140 214 170
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Golgi 9 4 3 17 11 15 24 21 3 6 11 4 9 10 0 53 47 25 8 3 5 8 18 26
Mitochondria 1 0 0 13 4 19 19 20 10 29 13 14 0 0 0 11 2 6 3 0 0 1 5 4
Nucleus 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 2 0 0 3 0 2 0 0 0 0 0 0 0 0 1 0 0 1
Nucleolus 1 0 0 0 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 1 0 4 2 0 0 0 0 0 0 1 0 0 0 0 1 0 0 3 5
Unique Cell Count 174 108 20 34 19 51 110 138 36 76 48 39 206 329 339 197 176 166 202 117 61 177 298 263
Labelled Cell Count 198 122 23 59 31 78 154 174 48 115 65 63 241 380 379 233 202 184 202 117 61 177 298 263


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 45.5 58.5 41.7 38.6 43.8 39.9 31.1 29.1 30.2 28.2 26.1 26.2 47.1 52.0 48.9 65.0 71.6 70.5 40.7 47.1 53.4
Std Deviation (1e-4) 7.7 8.5 12.1 11.0 10.3 9.2 8.6 10.0 6.0 6.2 5.5 8.0 11.8 9.0 8.8 21.6 23.3 21.6 11.7 13.3 17.7
Intensity Change (Log2) – – – -0.11 0.07 -0.06 -0.42 -0.52 -0.47 -0.57 -0.67 -0.67 0.18 0.32 0.23 0.64 0.78 0.76 -0.04 0.18 0.36


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 2.8 5.0 4.1 4.0 4.7
Endoplasmic Reticulum -2.4 -3.1 -2.0 -1.8 -1.5 -1.3 -1.2 -2.4 -2.5 -1.5 -2.6 -4.5 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 2.6 2.8 1.3 0 0 0 0 0 0 0 0 0 1.2 1.1 0
Mitochondria 0 0 3.2 0 0 0 3.3 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 35.7379 48.1602 45.0492 44.9957 34.7788 43.5 37.8582 45.3261 43.0919 37.1088 35.8206 42.088 44.5134 46.3075 46.2898 43.7259 37.3335 44.2755
Actin 0.03 0.0195 0.0049 0.0005 0.0069 0.0005 0.044 0.0137 0.044 0.0068 0.0089 0.0051 0.0135 0.0256 0.0147 0.0141 0.0352 0.0114
Bud 0.001 0.0011 0.0003 0 0.0005 0 0.0008 0.0004 0.0003 0.0003 0.0003 0.0001 0.0004 0.0003 0.0001 0.0004 0.0049 0.0005
Bud Neck 0.0066 0.0009 0.0008 0.0004 0.0022 0.0004 0.0008 0.0009 0.002 0.0012 0.0008 0.0017 0.0006 0.0012 0.0005 0.004 0.0045 0.0019
Bud Periphery 0.0019 0.0034 0.0007 0.0003 0.0012 0.0001 0.0013 0.0011 0.001 0.0013 0.001 0.0003 0.0009 0.0005 0.0003 0.0018 0.014 0.0016
Bud Site 0.0111 0.0069 0.0003 0 0.0005 0 0.0028 0.0018 0.0006 0.0002 0.0001 0.0001 0.0006 0.0017 0.0002 0.0005 0.001 0.0003
Cell Periphery 0.0061 0.0194 0.0167 0.0086 0.0071 0.0022 0.0041 0.0175 0.0104 0.0164 0.0011 0.0033 0.0123 0.0168 0.007 0.0156 0.0126 0.0026
Cytoplasm 0.0385 0.0784 0.0434 0.0077 0.0118 0.022 0.0589 0.043 0.009 0.0104 0.0153 0.0174 0.0251 0.0521 0.028 0.05 0.0351 0.0248
Cytoplasmic Foci 0.031 0.0114 0.0102 0.0002 0.0603 0.0087 0.0077 0.0056 0.0042 0.0026 0.0031 0.0019 0.0084 0.0068 0.0041 0.0025 0.0058 0.0023
Eisosomes 0.0014 0.0022 0.0043 0.0006 0.0003 0.0004 0.0012 0.0032 0.0145 0.0143 0.0002 0.0011 0.0021 0.0079 0.0012 0.0059 0.0021 0.0011
Endoplasmic Reticulum 0.5374 0.677 0.7664 0.8685 0.6185 0.8169 0.6515 0.7383 0.6819 0.7877 0.6632 0.7563 0.6885 0.7011 0.8035 0.7747 0.5881 0.7583
Endosome 0.0408 0.0141 0.012 0.0075 0.0558 0.012 0.0302 0.0166 0.0185 0.0194 0.0341 0.024 0.019 0.0165 0.0132 0.0175 0.0267 0.0195
Golgi 0.0208 0.0617 0.0564 0.0623 0.0852 0.0634 0.0345 0.0943 0.1455 0.0591 0.1473 0.0903 0.0328 0.0983 0.0737 0.0752 0.135 0.0948
Lipid Particles 0.025 0.0304 0.0218 0.0003 0.0566 0.0051 0.0107 0.0162 0.0174 0.0044 0.0017 0.0075 0.0121 0.032 0.02 0.0053 0.0129 0.0048
Mitochondria 0.0335 0.0107 0.0187 0.0018 0.025 0.0044 0.0126 0.0124 0.005 0.032 0.0564 0.0086 0.0063 0.006 0.0094 0.0046 0.04 0.0066
None 0.0049 0.0005 0.0006 0.0001 0.0004 0.0001 0.0129 0.0008 0.0022 0.0006 0.0005 0.0003 0.0021 0.0003 0.0003 0.0004 0.0046 0.0006
Nuclear Periphery 0.1336 0.0382 0.0274 0.0324 0.015 0.0553 0.0886 0.0209 0.0302 0.0264 0.0537 0.0638 0.1418 0.0243 0.0159 0.0184 0.0292 0.0574
Nucleolus 0.0011 0.0003 0.0002 0 0.0003 0 0.0007 0.0001 0.0001 0.0001 0.0001 0.0012 0.0017 0.0001 0.0002 0.0001 0.0008 0.0003
Nucleus 0.0118 0.0016 0.001 0.0009 0.0006 0.0007 0.006 0.0009 0.0028 0.0007 0.0018 0.0073 0.0057 0.0007 0.0006 0.0011 0.0022 0.0023
Peroxisomes 0.0162 0.0006 0.0008 0 0.0048 0.0002 0.0008 0.0001 0.0002 0.0005 0.0001 0 0.0009 0.0002 0.0002 0.0001 0.0008 0.0001
Punctate Nuclear 0.0105 0.0003 0.0004 0 0.003 0.0001 0.0063 0.0002 0.001 0.0001 0.0001 0.0005 0.0054 0.0002 0.0001 0.0002 0.0005 0.0004
Vacuole 0.0174 0.0143 0.0065 0.0039 0.0196 0.0031 0.0085 0.0078 0.0042 0.006 0.0035 0.003 0.0095 0.0044 0.0038 0.004 0.017 0.0032
Vacuole Periphery 0.0191 0.007 0.0063 0.0038 0.0244 0.0045 0.0151 0.0043 0.0052 0.0096 0.0069 0.0064 0.0104 0.0029 0.0029 0.0036 0.0267 0.0051

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 274.4845 236.6465 186.9979 217.3098 227.8045 314.5264 221.0982 193.6489 205.2746 234.0687
Translational Efficiency 3.0816 3.1277 3.1154 2.484 3.107 2.4995 2.2072 2.5351 2.352 2.3611

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1043 735 175 16 1133 28 100 20 2176 763 275 36

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 2054.37 2227.59 3426.06 332.77 2575.52 2464.41 5053.71 2842.21 2325.72 2236.28 4017.93 1726.90
Standard Deviation 534.27 594.76 1013.92 3.41 529.00 611.63 673.74 652.48 591.87 597.05 1196.79 1338.44
Intensity Change Log 2 — 0.116788 0.737854 -2.626099 — -0.063621 0.972479 0.142149 — 0.019225 0.873047 -0.544230

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.011557 0.014035 0.007920 0.000133 0.006498 0.001829 0.000890 0.006630 0.008923 0.013587 0.005364 0.003743
Bud Neck 0.001830 0.001526 0.004742 0.000045 0.000922 0.002723 0.016650 0.004302 0.001357 0.001570 0.009072 0.002410
Bud Site 0.022551 0.005527 0.022905 0.000068 0.001976 0.010687 0.001644 0.005554 0.011838 0.005716 0.015174 0.003116
Cell Periphery 0.013869 0.012251 0.017192 0.002569 0.005987 0.005864 0.022233 0.050146 0.009765 0.012016 0.019025 0.029001
Cytoplasm 0.016388 0.001381 0.003594 0.000902 0.000531 0.007055 0.000297 0.000090 0.008132 0.001589 0.002395 0.000451
Cytoplasmic Foci 0.069344 0.004972 0.013941 0.000032 0.001047 0.013475 0.000487 0.001748 0.033783 0.005284 0.009049 0.000985
Eisosomes 0.001698 0.005334 0.000695 0.005121 0.003759 0.000271 0.003282 0.002405 0.002771 0.005148 0.001636 0.003612
Endoplasmic Reticulum 0.623983* 0.565660* 0.238843* 0.000007 0.879172* 0.650950* 0.455326* 0.520251* 0.756855* 0.568789* 0.317564* 0.289031*
Endosome 0.030490 0.017877 0.037691 0.000002 0.006366 0.046281 0.016491 0.032555 0.017929 0.018920 0.029982 0.018087
Golgi 0.128334* 0.230952* 0.259072* 0.000020 0.059146 0.094473 0.062095 0.183350* 0.092309 0.225944* 0.187444* 0.101870
Lipid Particles 0.040981 0.083496 0.103006* 0.000319 0.014602 0.109228* 0.129948* 0.151961* 0.027246 0.084440 0.112803* 0.084565
Mitochondria 0.002836 0.006239 0.003895 0.000065 0.002345 0.003280 0.000890 0.000065 0.002580 0.006131 0.002802 0.000065
Mitotic Spindle 0.002271 0.000203 0.004265 0.000477 0.000169 0.001131 0.000525 0.000309 0.001176 0.000237 0.002905 0.000384
None 0.000583 0.002167 0.000623 0.987003* 0.000729 0.000341 0.000134 0.000101 0.000659 0.002100 0.000445 0.438724*
Nuclear Periphery 0.000770 0.001357 0.004822 0.000002 0.001997 0.000964 0.057960 0.001134 0.001408 0.001343 0.024145 0.000631
Nuclear Periphery Foci 0.006306 0.002328 0.022761 0.000004 0.001893 0.004679 0.059996 0.002801 0.004008 0.002414 0.036301 0.001558
Nucleolus 0.000691 0.001949 0.000071 0.000007 0.000024 0.000028 0.000073 0.000004 0.000343 0.001878 0.000072 0.000005
Nucleus 0.000759 0.004606 0.000322 0.000038 0.000279 0.004896 0.000307 0.000080 0.000509 0.004616 0.000317 0.000061
Peroxisomes 0.000507 0.000285 0.003407 0.003185 0.000074 0.000089 0.000006 0.000086 0.000281 0.000278 0.002170 0.001464
Vacuole 0.010882 0.014363 0.172659 0.000002 0.004190 0.032221 0.137978 0.029665 0.007398 0.015018 0.160048 0.016481
Vacuole Periphery 0.013371 0.023493 0.077573 0.000000 0.008295 0.009536 0.032786 0.006762 0.010728 0.022981 0.061287 0.003757

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.77 0.73 6.14 5.30 1.68 2.30 3.62 -0.02 -0.94 -1.25 -1.66 1.13 1.83 2.73 0.41
Bud Neck 0.77 -2.21 5.06 6.04 3.13 -1.31 -6.16 -1.31 -0.37 3.47 -0.72 -5.39 -0.70 -0.54 3.61
Bud Site 6.80 -0.33 11.20 3.68 3.67 -1.47 0.50 -1.78 0.92 -2.02 3.39 -1.02 5.71 1.46 2.96
Cell Periphery 0.68 -1.02 4.72 3.65 4.40 -0.05 -5.47 -1.84 -1.84 -1.15 -1.10 -4.17 -1.39 -1.22 -0.71
Cytoplasm 6.21 5.17 6.45 0.50 2.41 -1.62 1.08 1.61 1.81 1.88 4.92 4.58 6.64 1.47 3.02
Cytoplasmic Foci 14.04 10.31 15.39 6.06 5.02 -1.60 2.38 -1.22 1.50 -2.27 11.69 8.30 14.23 4.80 4.41
Eisosomes -2.77 1.55 -0.78 0.05 -1.02 4.87 0.30 1.00 -1.85 0.37 -1.94 1.45 -0.41 0.66 -0.96
Endoplasmic Reticulum 3.66 14.62 57.07* 49.88* 9.67 3.66 12.33 4.44 1.19 -0.83 14.49 20.37 7.47 4.42 0.35
Endosome 7.09 -1.57 22.00 15.95 8.68 -4.39 -6.75 -2.49 1.01 -1.49 -0.72 -4.07 -0.02 0.13 1.72
Golgi -10.22 -5.80 21.99 28.23 12.15 -1.65 -0.24 -2.27 -1.51 -2.21 -15.48 -6.08 -0.29 3.56 2.22
Lipid Particles -7.27 -4.59 13.64 16.53 7.82 -3.01 -5.79 -2.80 -0.77 -0.41 -10.95 -7.65 -1.92 -0.01 0.88
Mitochondria -1.87 -0.58 4.65 3.60 2.35 -0.52 1.70 2.76 1.03 3.31 -2.06 -0.15 4.87 3.69 2.62
Mitotic Spindle 3.70 -1.51 3.00 -0.92 2.84 -0.95 -1.69 -1.01 0.80 0.98 3.30 -2.03 2.71 -0.77 2.95
None -2.53 -0.16 -93.52* -93.21* -93.52* 0.94 2.62 2.75 1.14 0.78 -2.30 1.68 -5.28 -5.26 -5.28
Nuclear Periphery -3.73 -4.61 9.06 10.29 5.49 1.19 -6.94 1.79 0.06 7.05 0.29 -6.78 2.78 2.81 7.00
Nuclear Periphery Foci 4.41 -4.26 7.68 6.13 5.92 -2.07 -5.37 -1.33 1.41 5.29 2.72 -6.82 4.26 1.70 7.33
Nucleolus -1.15 0.98 1.10 2.15 5.08 -0.43 -2.66 2.76 1.08 4.10 -1.67 0.89 1.14 2.16 6.60
Nucleus -2.02 1.07 2.15 2.47 2.96 -0.93 0.62 1.14 1.00 4.55 -2.20 1.08 2.17 2.58 3.89
Peroxisomes 1.52 -0.92 -0.94 -1.01 0.04 -0.27 2.00 -0.25 0.03 -2.22 0.03 -0.94 -0.93 -0.93 0.29
Vacuole -1.45 -9.17 7.97 7.43 9.81 -2.38 -8.97 -2.95 0.31 6.38 -3.74 -12.24 -1.67 -0.23 10.66
Vacuole Periphery -4.06 -7.06 10.16 11.13 8.64 -0.22 -3.93 0.68 0.46 3.99 -5.58 -8.00 4.62 7.94 9.00
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Component of mRNP complexes associated with polyribosomes; involved in localization of mRNAs to P bodies; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity
Localization
Cell Percentages ER (83%)
Cell Cycle Regulation No
Subcompartmental Group ER-5

Bfr1

Bfr1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Bfr1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available