Standard name
Human Ortholog
Description Putative spore wall protein; expression increases during sporulation; not an essential gene; YOR214C has a paralog, SPO19, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0.07 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0.09 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.05 0.07 0.05 0 0 – 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0
Cytoplasm 0.6 0.75 0.67 0.79 0.76 0.55 0.58 – 0.49 0.62 0.57 0.6 0.85 0.88 0.93 0.89 0.83 0.82 0.12 0.31 0.13 0.28 0.3 0.3
Endoplasmic Reticulum 0.13 0.11 0.25 0.07 0.17 0 0 – 0 0.06 0 0.05 0.12 0.08 0 0.05 0 0.07 0.56 0.3 0.46 0.32 0.29 0.28
Endosome 0.08 0 0 0 0 0 0.1 – 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.09 0 0 0.07 0.06 0.45 0.17 – 0.49 0.48 0.42 0.34 0 0 0 0.06 0 0.06 0.16 0.16 0.28 0.22 0.2 0.16
Nucleus 0 0 0 0 0 0.05 0 – 0 0.08 0 0 0 0 0 0.07 0.07 0.07 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.15 0.07 0 0.07 0.07 0.14 0.18 – 0 0 0 0 0 0 0 0.07 0.13 0.06 0.05 0.07 0 0.08 0.08 0.09
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 3 7 4 2 3 0 0 – 0 1 0 0 1 3 0 0 0 2 9 10 4 6 6 9
Bud 2 3 0 0 2 2 1 – 1 1 0 5 0 0 0 0 0 3 2 7 2 1 6 12
Bud Neck 0 0 1 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 4 7 1 4 3 6
Bud Site 0 0 0 0 0 0 1 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 9 10 6 2 5 0 1 – 0 0 0 3 6 6 16 2 3 4 2 5 1 3 5 4
Cytoplasm 168 208 83 22 76 12 67 – 23 32 39 69 186 243 288 136 113 111 44 104 22 71 91 106
Endoplasmic Reticulum 36 31 31 2 17 0 4 – 0 3 0 6 27 23 12 8 6 10 205 101 78 81 90 97
Endosome 22 4 0 0 0 0 12 – 1 0 2 1 2 4 2 3 7 4 13 9 2 3 4 8
Golgi 0 5 1 0 0 0 0 – 0 0 0 0 0 1 0 0 0 0 3 4 0 0 5 2
Mitochondria 26 10 0 2 6 10 20 – 23 25 29 39 2 2 1 9 4 8 59 53 47 55 61 54
Nucleus 1 2 2 0 2 1 5 – 0 4 3 3 1 3 0 11 9 10 1 1 0 0 0 0
Nuclear Periphery 4 0 1 0 0 0 0 – 1 0 0 1 0 0 0 0 0 0 2 0 0 0 1 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 1 0 0 1 0 0 1 1 0 0 0 0 0 0
Peroxisomes 0 1 0 0 0 0 0 – 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
SpindlePole 0 1 2 0 1 0 0 – 1 0 1 0 0 0 0 0 0 0 0 1 0 1 2 5
Vac/Vac Membrane 41 20 5 2 7 3 21 – 1 0 1 5 6 5 3 11 18 8 17 22 6 19 24 32
Unique Cell Count 279 278 123 28 100 22 115 47 52 69 115 220 276 311 152 136 136 369 334 171 257 310 349
Labelled Cell Count 312 302 136 32 119 28 132 51 66 76 132 231 291 323 180 161 161 369 334 171 257 310 349


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.6 5.6 6.1 5.9 6.8 4.4 5.4 – 5.1 4.9 4.7 4.9 6.4 5.8 6.3 7.9 7.8 7.1 5.2 5.6 5.6
Std Deviation (1e-4) 0.9 1.2 1.2 1.7 1.7 1.7 1.5 – 1.9 1.5 1.5 1.2 1.4 1.4 1.8 2.2 1.9 1.9 1.4 1.7 1.8
Intensity Change (Log2) – – – -0.06 0.15 -0.48 -0.18 – -0.27 -0.32 -0.39 -0.33 0.06 -0.09 0.03 0.37 0.34 0.21 -0.25 -0.15 -0.13

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0.1 0 0 0
Cytoplasm 1.2 1.4 -1.2 -1.5 – -2.2 -0.8 -1.5 -1.2 3.7 4.9 6.7 4.5 2.9 2.6
Endoplasmic Reticulum -2.1 -1.5 0 -4.7 – -3.8 -3.0 0 -4.3 -3.1 -4.5 -6.7 -4.7 -4.8 -3.9
Endosome 0 0 0 3.7 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 4.8 – 8.3 8.3 0 7.1 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 2.2 2.0 2.2
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 1.0 0 3.5 – 0 0 0 0 0 0 0 1.1 2.6 0.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.411 1.6356 1.3662 1.2823 1.1007 1.619 2.6454 3.3229 3.1206 2.6944 3.1295 3.1782 5.4544 6.7056 5.7349 5.4581 5.4957 5.5957
Actin 0.0244 0.0029 0.014 0.0109 0.0132 0.0171 0.0497 0.0047 0.0071 0.0442 0.0011 0.0081 0.1228 0.0008 0.0041 0.0027 0.0019 0.0024
Bud 0.0007 0.0006 0.0008 0.0012 0.0027 0.0005 0.0006 0.0029 0.0005 0.0017 0.0001 0.0008 0.0008 0 0.0003 0.0003 0.0001 0.0001
Bud Neck 0.0044 0.0017 0.0015 0.003 0.0011 0.0091 0.001 0.0007 0.0013 0.002 0.0005 0.0079 0.0052 0.0002 0.0014 0.0029 0.0009 0.0034
Bud Periphery 0.0012 0.0007 0.0015 0.0041 0.0061 0.0013 0.0008 0.0015 0.0007 0.0017 0.0002 0.0014 0.0021 0.0001 0.0005 0.0006 0.0003 0.0003
Bud Site 0.009 0.0328 0.0031 0.007 0.0021 0.0008 0.0067 0.0113 0.0034 0.0015 0.0001 0.0005 0.0062 0.0009 0.0016 0.0007 0.0002 0.0009
Cell Periphery 0.0019 0.0022 0.0019 0.0099 0.0008 0.001 0.0013 0.003 0.0014 0.0025 0.0007 0.0011 0.002 0.0016 0.002 0.0019 0.0012 0.0013
Cytoplasm 0.2086 0.3794 0.3501 0.2801 0.2967 0.3853 0.2998 0.5051 0.4033 0.3563 0.3844 0.4197 0.2382 0.4174 0.4234 0.4995 0.4414 0.4343
Cytoplasmic Foci 0.0398 0.0234 0.0418 0.0523 0.0496 0.0228 0.0474 0.0176 0.0119 0.0195 0.0108 0.0207 0.013 0.0073 0.0146 0.0304 0.012 0.0122
Eisosomes 0.0005 0.0006 0.0002 0.0014 0.0003 0.0005 0.0005 0.0002 0.0001 0.0002 0 0.0002 0.0009 0.0001 0.0001 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.3831 0.2831 0.3716 0.3254 0.257 0.3781 0.3014 0.3306 0.4354 0.3726 0.5044 0.3938 0.4189 0.3707 0.42 0.2937 0.3659 0.4002
Endosome 0.1193 0.0362 0.064 0.1228 0.1085 0.0628 0.0674 0.0468 0.0547 0.0802 0.049 0.0579 0.0344 0.0264 0.0277 0.0688 0.0412 0.0208
Golgi 0.0146 0.0037 0.0133 0.0186 0.0334 0.011 0.0136 0.0071 0.0104 0.0184 0.0027 0.0059 0.0087 0.0018 0.0055 0.0066 0.0031 0.0022
Lipid Particles 0.0312 0.0048 0.0122 0.011 0.0354 0.0183 0.041 0.0128 0.0074 0.0124 0.002 0.0108 0.0086 0.0098 0.0092 0.0172 0.0074 0.013
Mitochondria 0.0096 0.002 0.0105 0.0212 0.0405 0.0116 0.0101 0.0032 0.0047 0.0098 0.003 0.0144 0.0214 0.0481 0.001 0.0012 0.0741 0.0029
None 0.0755 0.1927 0.068 0.0565 0.0601 0.0468 0.0782 0.0222 0.0296 0.0274 0.0186 0.0251 0.0838 0.0928 0.0503 0.0584 0.027 0.0875
Nuclear Periphery 0.0308 0.0093 0.0158 0.0296 0.0175 0.0143 0.0386 0.0105 0.0107 0.0127 0.0089 0.0129 0.0144 0.0093 0.0108 0.005 0.0099 0.008
Nucleolus 0.0011 0.0008 0.0003 0.0007 0.0005 0.0002 0.0031 0.0003 0.0005 0.0003 0 0.0002 0.0004 0 0.0001 0.0001 0.0001 0.0001
Nucleus 0.0055 0.0046 0.0034 0.0144 0.0064 0.0041 0.0069 0.0035 0.0026 0.0036 0.0028 0.0039 0.0038 0.0019 0.0027 0.0015 0.0026 0.0024
Peroxisomes 0.0096 0.0004 0.0102 0.0051 0.0376 0.0032 0.0083 0.0004 0.0007 0.0133 0.0001 0.0012 0.0031 0.0001 0.0129 0.0006 0.0002 0.0003
Punctate Nuclear 0.005 0.0058 0.0028 0.0062 0.0173 0.0024 0.0102 0.0017 0.0007 0.0028 0.0013 0.0031 0.0035 0.0005 0.0007 0.0007 0.0007 0.0015
Vacuole 0.02 0.011 0.0107 0.0139 0.0094 0.007 0.0092 0.0129 0.0114 0.0135 0.0071 0.0083 0.0061 0.0083 0.01 0.0063 0.0086 0.0053
Vacuole Periphery 0.0041 0.0012 0.0025 0.0047 0.0039 0.0018 0.0042 0.0011 0.0019 0.0035 0.0019 0.002 0.0016 0.002 0.0012 0.0007 0.0013 0.0008

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression – – – – – – – – – –
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression –
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2291 1129 1391 1402 1374 2543 2165 1056 3665 3672 3556 2458

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 766.42 806.30 964.13 921.20 727.96 811.99 938.46 966.52 752.00 810.24 948.50 940.67
Standard Deviation 96.70 105.03 125.20 149.00 79.85 97.17 132.77 130.83 92.64 99.69 130.46 143.25
Intensity Change Log 2 — 0.073182 0.331092 0.265379 — 0.157603 0.366436 0.408940 — 0.114923 0.348418 0.337098

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000748 0.002520 0.000778 0.003363 0.000317 0.002521 0.000843 0.003031 0.000587 0.002521 0.000818 0.003220
Bud Neck 0.026233 0.035560 0.007387 0.015005 0.012593 0.045202 0.011895 0.011871 0.021120 0.042237 0.010132 0.013658
Bud Site 0.008918 0.035514 0.012831 0.046639 0.004405 0.032287 0.013585 0.046894 0.007226 0.033279 0.013290 0.046749
Cell Periphery 0.000450 0.000655 0.000477 0.000976 0.000273 0.000445 0.000543 0.000621 0.000384 0.000509 0.000517 0.000824
Cytoplasm 0.331759 0.229355 0.394663 0.387097 0.415696 0.280482 0.460453 0.378941 0.363227 0.264762 0.434718 0.383593
Cytoplasmic Foci 0.240524 0.302827 0.032483 0.063436 0.267040 0.266561 0.036025 0.071609 0.250465 0.277711 0.034640 0.066947
Eisosomes 0.000690 0.000607 0.000085 0.000357 0.000360 0.000654 0.000119 0.000219 0.000566 0.000640 0.000106 0.000298
Endoplasmic Reticulum 0.044003 0.053009 0.074854 0.034740 0.015831 0.025833 0.051298 0.043192 0.033441 0.034188 0.060513 0.038371
Endosome 0.029184 0.056448 0.008331 0.016589 0.017177 0.035480 0.006218 0.012314 0.024682 0.041927 0.007045 0.014752
Golgi 0.015706 0.030628 0.000769 0.005984 0.004589 0.023000 0.000292 0.003218 0.011538 0.025345 0.000479 0.004796
Lipid Particles 0.060886 0.039804 0.008518 0.010200 0.034706 0.037006 0.007818 0.012170 0.051071 0.037866 0.008092 0.011047
Mitochondria 0.024959 0.028347 0.000641 0.003887 0.006021 0.040178 0.000953 0.001087 0.017860 0.036540 0.000831 0.002684
Mitotic Spindle 0.003085 0.003834 0.001782 0.023433 0.001665 0.005562 0.008927 0.020725 0.002553 0.005031 0.006132 0.022269
None 0.002415 0.001029 0.001542 0.004080 0.002329 0.002065 0.003423 0.003044 0.002382 0.001746 0.002687 0.003635
Nuclear Periphery 0.002880 0.001326 0.018402 0.003603 0.003022 0.000947 0.011226 0.003165 0.002933 0.001064 0.014033 0.003415
Nuclear Periphery Foci 0.001821 0.002998 0.030927 0.012368 0.002628 0.001136 0.013973 0.012972 0.002124 0.001708 0.020605 0.012627
Nucleolus 0.001234 0.001226 0.000417 0.000863 0.001218 0.001522 0.000475 0.000609 0.001228 0.001431 0.000452 0.000754
Nucleus 0.110882 0.049086 0.291428 0.121071 0.148453 0.089408 0.241779 0.109657 0.124967 0.077011 0.261200 0.116168
Peroxisomes 0.012104 0.021967 0.000551 0.002430 0.005913 0.018662 0.000822 0.001970 0.009783 0.019678 0.000716 0.002232
Vacuole 0.077303 0.093698 0.112850 0.240279 0.054264 0.084498 0.129042 0.260023 0.068666 0.087326 0.122708 0.248761
Vacuole Periphery 0.004217 0.009564 0.000282 0.003602 0.001500 0.006553 0.000290 0.002667 0.003198 0.007479 0.000287 0.003200

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.06 -0.71 -4.50 -0.22 -4.31 -5.34 -3.71 -3.01 0.41 -2.14 -6.07 -2.35 -5.17 0.12 -4.42
Bud Neck -3.41 11.47 7.78 8.85 -3.58 -15.36 0.15 1.54 17.24 1.57 -12.10 9.21 7.89 18.76 -1.22
Bud Site -10.72 -2.45 -9.41 -0.25 -6.84 -14.95 -6.68 -8.81 -0.50 -5.93 -17.52 -5.68 -12.76 -0.84 -9.27
Cell Periphery -1.74 -1.34 -2.75 -0.74 -2.34 -3.82 -5.48 -4.11 -0.52 0.58 -2.55 -3.88 -3.72 -1.67 -1.86
Cytoplasm 11.85 -5.52 -3.38 -13.12 1.62 16.17 -2.40 6.76 -6.28 9.24 17.00 -8.32 1.31 -12.93 8.41
Cytoplasmic Foci -8.30 47.47 39.34 36.96 -7.87 0.10 39.47 32.28 40.82 -7.80 -5.63 61.96 50.74 56.17 -10.94
Eisosomes 1.37 14.81 5.07 3.84 -2.69 -6.49 9.80 6.81 11.83 -4.70 -1.77 16.91 6.80 7.95 -3.17
Endoplasmic Reticulum -1.78 -6.04 5.44 5.70 10.64 -4.28 -9.58 -3.64 -0.72 4.07 -0.26 -7.85 2.66 2.86 10.00
Endosome -9.86 16.77 10.79 16.34 -3.24 -12.23 11.33 6.69 18.63 -3.36 -12.36 20.71 12.96 23.50 -5.11
Golgi -6.98 15.88 10.54 12.79 -3.49 -16.73 13.08 4.12 17.58 -2.57 -12.63 19.47 11.61 20.91 -4.67
Lipid Particles 6.68 24.61 24.17 12.76 -0.13 -1.05 15.98 13.91 16.58 -2.55 6.82 29.08 27.55 21.44 -2.03
Mitochondria -1.30 17.35 14.77 12.03 -3.63 -17.27 5.65 5.82 22.24 0.99 -11.11 17.90 15.94 24.45 -3.14
Mitotic Spindle -0.60 1.02 -6.46 -6.16 -7.01 -3.54 -5.25 -5.54 -4.21 -2.60 -2.93 -4.23 -8.45 -7.13 -5.89
None 3.29 2.28 -0.83 -2.85 -2.23 0.60 -1.31 -0.25 -0.67 0.84 1.96 -0.29 -0.82 -2.15 -0.55
Nuclear Periphery 3.39 -10.04 -1.18 -4.40 9.42 6.09 -8.35 -0.49 -5.98 7.90 6.41 -12.90 -1.26 -7.41 12.07
Nuclear Periphery Foci -2.96 -17.44 -8.71 -7.04 10.35 3.30 -11.43 -8.49 -11.17 2.50 1.61 -21.08 -12.16 -12.85 8.92
Nucleolus 0.01 7.41 1.99 1.61 -2.06 -1.19 5.09 3.78 3.81 -0.48 -1.15 8.79 3.71 3.60 -1.97
Nucleus 15.15 -25.79 -2.86 -14.96 21.72 11.14 -14.84 5.29 -4.99 20.27 14.53 -30.53 1.00 -11.76 29.20
Peroxisomes -5.92 18.87 16.03 12.94 -5.77 -13.27 9.92 8.37 20.77 -4.12 -11.61 21.05 18.10 24.04 -6.74
Vacuole -3.80 -10.76 -29.48 -25.56 -19.93 -9.02 -21.79 -31.86 -28.40 -18.96 -6.99 -22.30 -42.78 -38.93 -26.78
Vacuole Periphery -6.72 15.86 3.61 8.18 -4.44 -10.53 9.87 -0.03 7.02 -2.29 -9.96 17.90 3.15 10.34 -4.84
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative spore wall protein; expression increases during sporulation; not an essential gene; YOR214C has a paralog, SPO19, that arose from the whole genome duplication
Localization
Cell Percentages ER (26%), cytoplasm (12%), mixed (35%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Spr2

Spr2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Spr2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available