Standard name
Human Ortholog
Description Protein of unknown function; the authentic protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0.12 0.09 0.1 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.09 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0.05 0.08 0.08 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.07 0 0.06 0.06 0 0 – 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Endosome 0 0 0.06 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0.23 0.08 0.42 0 0.06 0.08 0 0 – 0 0.09 0.14 0.2 0.47 0.55 0.23 0.05 0.08 0.07 0.05 0.05 0.05
Mitochondria 0.87 0.9 0.83 0.92 0.72 0.91 0.84 0.82 0.86 0.9 – 0.88 0.88 0.89 0.86 0.08 0.12 0.08 0.77 0.78 0.79 0.78 0.76 0.76
Nucleus 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0.09 0.05 0 0 0 0.07 0.07 0.07 0.07 0.05 – 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.06 0 0 0.05 0 0.06 0.09 0.08 0.16 0.12 – 0.31 0 0 0 0.09 0.07 0.22 0 0 0 0 0 0
Peroxisomes 0.06 0 0.05 0.09 0 0 0 0 0 0 – 0 0.14 0.09 0.07 0.08 0.05 0.09 0.06 0 0.08 0.08 0.07 0.06
SpindlePole 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.07 0.1 0.06 0 0.1 0 0.08 0 0 0 – 0 0.07 0.05 0.05 0.15 0.15 0.15 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 1 0 2 0 1 3 0 1 – 0 5 16 9 33 19 22 8 7 0 10 37 38
Bud 2 2 3 1 3 1 1 4 4 3 – 0 6 6 8 7 3 19 2 1 0 5 9 7
Bud Neck 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 0 0 2 3
Bud Site 1 2 0 0 0 1 0 0 0 1 – 0 0 0 0 0 0 4 – – – – – –
Cell Periphery 5 15 2 1 4 0 1 2 0 1 – 0 16 25 22 14 17 18 0 2 0 0 2 2
Cytoplasm 7 6 3 1 9 4 10 15 4 5 – 1 10 12 10 8 6 6 0 0 0 0 0 3
Endoplasmic Reticulum 2 0 1 0 0 0 0 1 1 0 – 0 0 3 4 7 3 11 0 1 0 0 2 4
Endosome 7 3 7 3 1 0 2 2 0 1 – 0 14 17 17 2 4 0 13 7 2 12 20 24
Golgi 3 12 29 8 53 1 10 21 4 2 – 0 63 121 157 124 119 52 17 31 10 32 52 49
Mitochondria 275 354 105 94 90 116 138 224 144 137 – 14 592 783 689 22 26 18 260 317 110 514 759 722
Nucleus 1 0 0 0 0 0 0 2 1 0 – 0 1 1 0 4 2 0 0 1 0 0 0 1
Nuclear Periphery 30 20 5 3 4 9 11 18 12 8 – 1 23 33 21 5 5 9 3 1 1 5 4 8
Nucleolus 20 9 4 5 4 8 14 23 26 18 – 5 20 20 11 25 15 48 0 1 1 3 9 4
Peroxisomes 19 13 6 9 1 0 1 7 2 4 – 0 92 77 53 20 11 20 20 11 11 54 71 55
SpindlePole 3 5 1 2 1 1 2 5 2 1 – 0 6 3 5 3 3 5 2 0 0 3 7 4
Vac/Vac Membrane 23 39 7 1 12 5 13 8 6 2 – 0 45 47 38 40 32 34 1 16 0 10 11 11
Unique Cell Count 316 393 126 102 125 127 164 272 167 153 16 670 883 803 266 217 223 337 405 141 656 997 948
Labelled Cell Count 399 480 174 128 184 146 204 335 206 184 21 893 1164 1044 314 265 266 337 405 141 656 997 948


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.2 10.8 10.5 10.8 13.8 9.9 14.5 14.9 13.6 13.6 – 12.6 14.9 15.3 15.8 24.9 25.5 22.5 10.9 12.0 12.6
Std Deviation (1e-4) 5.3 2.7 2.1 2.3 3.1 2.7 4.2 4.7 4.7 4.5 – 5.4 5.4 3.9 4.5 8.1 8.4 7.5 3.9 5.8 3.5
Intensity Change (Log2) – – – 0.05 0.39 -0.09 0.46 0.5 0.37 0.38 – 0.27 0.5 0.54 0.59 1.25 1.28 1.1 0.05 0.19 0.26


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 3.8 3.0 3.3
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 2.3
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 1.7 2.4 2.5
Cytoplasm 0 1.8 0 1.5 1.4 0 0 – 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Golgi -3.1 3.3 -5.5 -4.2 -4.3 -5.5 -5.7 – 0 -4.4 -2.7 -0.9 4.5 5.7 0.1
Mitochondria 2.0 -2.2 1.9 0.2 -0.2 0.7 1.5 – 0.4 1.6 1.7 0.7 -14.8 -13.1 -14.1
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nuclear Periphery 0 0 1.1 1.0 1.1 1.2 0.5 – 0 0 0 0 0 0 0
Nucleolus 0 0 1.2 1.9 1.9 3.5 2.6 – 0 0 0 0 2.2 1.5 4.6
Peroxisomes 1.2 0 0 0 0 0 0 – 0 2.8 1.5 0.8 1.0 0.1 1.4
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Vacuole 0 1.2 -0.6 0.8 0 -0.8 0 – 0 0.5 -0.1 -0.4 2.7 2.6 2.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 12.4252 12.0673 11.7415 10.5861 11.4048 11.1757 15.271 13.9804 14.3238 13.8196 13.9341 15.0443 19.2146 17.7853 16.5819 14.3717 15.788 16.3422
Actin 0.0109 0.0016 0.0054 0.0001 0.0018 0.0001 0.0064 0.0053 0.0011 0.0005 0.0005 0.0008 0.0017 0.0097 0.0042 0.0014 0.0006 0.0004
Bud 0 0.0001 0.0013 0 0 0 0.0002 0.0006 0.0006 0 0.0003 0 0 0.0005 0 0 0 0.0001
Bud Neck 0 0 0.0002 0 0 0 0.0001 0.0006 0.0001 0 0 0.0001 0 0.0001 0 0 0 0
Bud Periphery 0.0001 0.0002 0.0028 0.0002 0.0001 0 0.0004 0.0016 0.0016 0.0001 0.0009 0.0001 0.0001 0.001 0.0001 0.0002 0 0.0001
Bud Site 0.0001 0.0002 0.0045 0 0 0 0.0006 0.002 0.0015 0 0.0001 0.0001 0.0002 0.0014 0.0001 0 0 0.0001
Cell Periphery 0.0001 0.0002 0.0005 0.0001 0.0001 0 0.0004 0.0014 0.0005 0.0001 0.0004 0.0002 0.0002 0.0006 0 0.0001 0 0
Cytoplasm 0 0 0.0001 0 0 0 0.0008 0.0001 0.0001 0 0.0001 0 0 0.0001 0 0 0 0.0001
Cytoplasmic Foci 0.0004 0.0014 0.0012 0 0.0003 0.0001 0.0036 0.0038 0.0009 0.0005 0.0024 0.0004 0.0004 0.0021 0.0001 0.0001 0 0.0006
Eisosomes 0.0002 0.0001 0.0002 0.0001 0.0002 0.0001 0.0006 0.0003 0.0001 0.0001 0.0001 0.0002 0.0004 0.0002 0.0002 0.0002 0.0003 0.0001
Endoplasmic Reticulum 0 0 0.0001 0.0001 0.0001 0 0.001 0.0011 0.0001 0 0.0002 0 0.0001 0.0001 0 0.0001 0 0
Endosome 0.0013 0.0044 0.0026 0.002 0.0031 0.0011 0.0107 0.0152 0.0054 0.0031 0.0034 0.0033 0.0009 0.0044 0.0001 0.0009 0 0.0096
Golgi 0.0044 0.0149 0.0106 0.0012 0.0185 0.0043 0.0073 0.0276 0.0172 0.0086 0.0052 0.012 0.0019 0.0118 0.0003 0.0024 0.0001 0.0076
Lipid Particles 0.0101 0.0078 0.0081 0.0005 0.005 0.0006 0.0091 0.0068 0.0077 0.0006 0.0017 0.005 0.0104 0.0069 0.0008 0.0005 0 0.0072
Mitochondria 0.9559 0.9502 0.9411 0.9874 0.966 0.9914 0.9245 0.875 0.9442 0.984 0.9455 0.9687 0.9755 0.9462 0.9887 0.9918 0.9982 0.9694
None 0 0 0 0 0 0 0.0011 0.0001 0 0 0.0005 0 0.0002 0 0 0 0 0
Nuclear Periphery 0 0 0.0001 0 0 0 0.0032 0.0006 0.0001 0 0.0005 0.0001 0.0003 0 0 0 0 0.0001
Nucleolus 0.0006 0.0004 0.0022 0 0 0 0.002 0.0011 0.0002 0 0.0098 0.0004 0.0008 0.0002 0 0 0 0
Nucleus 0.0001 0.0002 0.0005 0 0 0 0.0022 0.0008 0.0001 0 0.0022 0.0001 0.0004 0.0001 0 0 0 0
Peroxisomes 0.0086 0.0072 0.0034 0.0004 0.0009 0.0004 0.004 0.0036 0.0028 0.001 0.0005 0.0021 0.0014 0.0103 0.0037 0.0011 0.0005 0.0008
Punctate Nuclear 0 0 0 0 0 0 0.0034 0 0 0 0.0086 0 0.0001 0 0 0 0 0
Vacuole 0.0007 0.0025 0.0054 0.0021 0.0003 0.0002 0.0077 0.0237 0.0063 0.0002 0.0083 0.0015 0.0008 0.0017 0.0002 0.0002 0 0.0009
Vacuole Periphery 0.0062 0.0084 0.0097 0.0056 0.0033 0.0017 0.011 0.0287 0.0093 0.001 0.0087 0.0049 0.0043 0.0025 0.0015 0.0009 0.0002 0.0029

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 15.8194 22.9801 22.2991 44.5024 28.202 33.5977 25.9161 40.4117 51.6345 40.3699
Translational Efficiency 5.4203 2.6196 4.405 2.6803 3.0512 3.9659 3.3167 2.7782 2.8466 2.4668

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1503 290 1932 233 741 2280 984 1454 2244 2570 2916 1687

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 883.61 1152.87 1452.56 1968.56 1018.15 1142.45 1563.31 1498.78 928.04 1143.63 1489.93 1563.66
Standard Deviation 142.35 213.51 364.35 436.48 204.17 235.06 349.31 356.00 177.03 232.75 363.14 402.26
Intensity Change Log 2 — 0.383748 0.717116 1.155659 — 0.166181 0.618654 0.557839 — 0.271360 0.665239 0.866494

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001164 0.011238 0.004066 0.008356 0.003414 0.001947 0.005679 0.002456 0.001907 0.002995 0.004611 0.003271
Bud Neck 0.000463 0.002505 0.002599 0.005138 0.001648 0.001002 0.002029 0.000991 0.000854 0.001172 0.002407 0.001564
Bud Site 0.001216 0.005994 0.003490 0.002187 0.004860 0.001894 0.003505 0.002160 0.002419 0.002357 0.003495 0.002164
Cell Periphery 0.000312 0.000331 0.000117 0.000298 0.000968 0.000196 0.000176 0.000974 0.000529 0.000211 0.000137 0.000881
Cytoplasm 0.000248 0.000703 0.000339 0.000194 0.000900 0.000400 0.000547 0.000385 0.000463 0.000434 0.000410 0.000359
Cytoplasmic Foci 0.004501 0.022100 0.014636 0.015446 0.017193 0.010220 0.012199 0.007575 0.008692 0.011561 0.013813 0.008662
Eisosomes 0.000043 0.000262 0.000410 0.001232 0.000166 0.000142 0.000487 0.000251 0.000084 0.000156 0.000436 0.000386
Endoplasmic Reticulum 0.000139 0.000296 0.000130 0.001972 0.000289 0.000141 0.000104 0.000539 0.000188 0.000159 0.000121 0.000737
Endosome 0.008658 0.022459 0.004876 0.003496 0.014625 0.011698 0.002618 0.003670 0.010628 0.012912 0.004114 0.003646
Golgi 0.007935 0.041637 0.021623 0.042683 0.022389 0.021820 0.012427 0.026325 0.012708 0.024056 0.018520 0.028584
Lipid Particles 0.001735 0.002970 0.008076 0.006982 0.009258 0.004501 0.002960 0.002101 0.004219 0.004328 0.006350 0.002775
Mitochondria 0.954498* 0.849228* 0.903796* 0.854209* 0.883557* 0.922975* 0.923805* 0.927045* 0.931072* 0.914653* 0.910548* 0.916985*
Mitotic Spindle 0.000880 0.003796 0.003790 0.002943 0.001924 0.001301 0.003224 0.001038 0.001225 0.001583 0.003599 0.001301
None 0.000268 0.000440 0.002050 0.003497 0.000702 0.000903 0.001215 0.001145 0.000412 0.000851 0.001768 0.001470
Nuclear Periphery 0.000042 0.000206 0.002313 0.001995 0.000345 0.000151 0.000639 0.000342 0.000142 0.000157 0.001748 0.000570
Nuclear Periphery Foci 0.000288 0.000296 0.000794 0.000637 0.000497 0.000230 0.000278 0.000251 0.000357 0.000238 0.000620 0.000305
Nucleolus 0.000071 0.000079 0.000716 0.000330 0.000253 0.000440 0.000360 0.000324 0.000131 0.000399 0.000596 0.000325
Nucleus 0.000037 0.000070 0.000069 0.000047 0.000132 0.000123 0.000047 0.000046 0.000068 0.000117 0.000062 0.000047
Peroxisomes 0.014542 0.027266 0.007029 0.012805 0.024444 0.008186 0.017762 0.007091 0.017812 0.010339 0.010651 0.007880
Vacuole 0.001272 0.004270 0.006789 0.007785 0.005294 0.006390 0.004072 0.005505 0.002600 0.006151 0.005872 0.005820
Vacuole Periphery 0.001688 0.003854 0.012294 0.027768 0.007143 0.005339 0.005868 0.009784 0.003489 0.005171 0.010125 0.012268

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.64 -4.03 -3.19 0.64 -1.84 1.79 -1.42 1.15 -1.06 2.21 -1.80 -3.77 -2.56 -0.42 1.70
Bud Neck -2.88 -5.17 -2.86 -1.49 -1.51 1.87 -0.82 2.02 0.02 2.51 -1.42 -4.90 -2.51 -1.24 2.13
Bud Site -1.65 -2.94 -1.38 1.28 1.35 1.82 0.72 1.62 -0.40 1.20 0.08 -1.37 0.32 0.25 1.78
Cell Periphery -0.09 1.32 0.08 0.19 -2.19 1.90 1.92 -0.01 -1.17 -1.19 1.87 2.33 -0.59 -1.17 -1.30
Cytoplasm -1.85 -1.45 0.82 2.08 2.55 1.33 0.87 1.37 0.12 0.90 0.20 0.36 0.73 0.76 0.59
Cytoplasmic Foci -4.78 -8.45 -3.37 1.37 -0.23 3.33 2.13 4.48 2.02 2.78 -2.50 -4.60 0.01 2.24 4.09
Eisosomes -3.67 -11.12 -4.53 -3.60 -3.11 0.98 -5.69 -2.92 -4.02 4.07 -4.47 -12.15 -7.13 -5.19 0.98
Endoplasmic Reticulum -1.69 0.13 -1.70 -1.55 -1.71 2.72 3.10 -0.77 -1.24 -1.35 0.60 1.39 -1.73 -1.84 -1.96
Endosome -3.22 3.18 3.88 4.48 1.46 1.46 6.69 6.13 7.37 -1.71 -1.68 6.56 7.03 8.60 0.87
Golgi -5.77 -6.81 -4.98 -0.12 -2.95 0.18 3.31 -1.11 -1.49 -4.77 -5.68 -3.47 -6.20 -1.57 -3.77
Lipid Particles -1.62 -6.81 -2.41 -1.79 0.48 2.26 3.00 3.48 3.19 1.16 -0.12 -2.29 1.69 2.12 4.62
Mitochondria 6.50 8.41 6.02 -0.21 2.92 -4.09 -3.84 -4.32 -0.62 -0.42 2.94 3.86 2.30 -0.35 -1.07
Mitotic Spindle -1.79 -3.56 -1.26 0.35 0.45 1.43 -1.41 2.18 0.96 2.55 -1.15 -3.81 -0.27 0.73 3.48
None -3.79 -14.95 -7.88 -7.45 -3.41 -0.68 -3.38 -3.32 -0.51 0.65 -1.52 -14.41 -11.96 -1.73 2.64
Nuclear Periphery -2.02 -4.90 -3.35 -3.04 0.43 2.10 -1.26 0.02 -1.89 1.25 -0.43 -5.06 -3.49 -3.45 3.49
Nuclear Periphery Foci 0.04 -1.65 -1.10 -1.71 0.77 1.42 1.10 1.21 -0.20 0.21 0.70 -1.21 0.32 -0.71 2.44
Nucleolus -0.15 -2.26 -2.89 -2.85 1.32 -1.11 -1.09 -0.66 0.67 0.30 -1.92 -2.42 -2.47 0.50 1.32
Nucleus -1.12 -1.85 -0.56 0.90 2.17 0.10 1.98 1.95 2.02 -0.03 -1.33 0.37 1.15 2.08 1.66
Peroxisomes -2.05 3.54 0.34 1.90 -1.19 4.45 1.56 4.66 0.75 4.02 3.71 3.56 4.76 1.56 1.77
Vacuole -2.35 -8.18 -3.99 -1.74 -0.55 -0.96 1.09 -0.24 0.72 -1.39 -4.95 -5.66 -3.80 0.25 0.02
Vacuole Periphery -2.07 -10.70 -4.34 -3.93 -2.54 1.65 0.99 -1.77 -3.56 -2.78 -2.89 -8.45 -6.53 -5.16 -1.44
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; the authentic protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss
Localization
Cell Percentages mitochondrion (100%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Aim41

Aim41


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Aim41-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available