Standard name
Human Ortholog
Description Protein of unknown function; required for proliferation or remodeling of the ER that is caused by overexpression of Hmg2p; may interact with ribosomes, based on co-purification experiments; HER1 has a paralog, GIP3, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0.05 0.05 0 0 0 0 0 0
Cytoplasm 0.98 0.97 0.98 0.98 0.95 0.89 0.86 0.79 0.75 – 0.66 0.64 1.0 0.97 0.98 0.88 0.93 0.92 0.91 0.86 0.82 0.9 0.88 0.84
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.08 0 0.13 0.12 0.37 0.36 0.41 0.51 – 0.6 0.6 0 0 0.06 0 0 0 0 0 0.09 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 0 – 0 0 0 1 0 0 0 0 1 0 2 1 0 4
Bud 0 0 3 3 3 5 1 11 13 – 13 14 2 1 7 0 0 0 1 0 1 2 2 6
Bud Neck 0 0 3 0 1 0 0 0 0 – 0 0 0 0 0 0 0 0 1 0 1 0 0 5
Bud Site 0 0 1 0 0 0 0 0 0 – 1 2 0 0 0 0 0 0 – – – – – –
Cell Periphery 10 1 4 3 1 2 8 2 12 – 12 15 2 0 3 11 9 9 1 0 1 0 0 1
Cytoplasm 321 100 321 318 319 271 349 311 294 – 214 278 234 294 329 179 184 151 318 103 291 144 211 243
Endoplasmic Reticulum 2 0 1 0 0 0 0 0 1 – 3 1 0 2 1 6 13 6 1 0 0 3 1 3
Endosome 2 0 0 1 4 0 1 0 0 – 0 0 0 0 0 6 1 0 3 1 2 1 0 3
Golgi 0 0 1 0 0 0 0 0 0 – 0 0 0 0 0 5 1 2 1 0 2 0 0 3
Mitochondria 1 8 11 42 41 112 145 162 197 – 195 261 4 6 20 8 3 2 10 4 30 1 8 6
Nucleus 0 0 0 1 1 1 1 1 2 – 0 0 0 2 0 7 2 3 1 1 0 0 1 0
Nuclear Periphery 1 0 0 0 0 0 0 1 0 – 2 1 0 1 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 1 0 0 1 0 5 1 0 0 1 0 0 0 0
Peroxisomes 0 0 0 0 0 0 1 0 0 – 0 0 0 0 0 1 1 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 1 1 0 2 – 1 1 0 0 0 1 1 0 1 0 0 1 1 1
Vac/Vac Membrane 2 0 1 1 0 2 3 7 5 – 4 10 1 0 0 8 6 5 0 2 11 1 3 4
Unique Cell Count 327 103 327 326 335 303 405 395 390 323 433 235 304 335 204 197 165 351 120 354 161 240 290
Labelled Cell Count 339 109 346 369 370 394 510 496 526 446 583 243 308 360 237 222 178 351 120 354 161 240 290


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.1 4.3 3.6 3.5 4.1 4.0 3.9 4.2 3.8 – 3.8 3.7 4.5 4.9 4.5 7.3 7.8 7.0 4.8 4.5 5.4
Std Deviation (1e-4) 0.6 1.0 0.8 1.0 1.3 1.4 1.1 1.3 1.2 – 1.0 1.0 1.4 1.3 1.3 2.8 3.6 2.2 1.8 1.6 1.8
Intensity Change (Log2) – – – -0.05 0.19 0.13 0.1 0.22 0.06 – 0.05 0.04 0.3 0.42 0.3 1.0 1.1 0.94 0.4 0.31 0.56


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.194 3.0428 2.931 3.1929 2.9637 3.1521 2.3384 2.3428 1.9444 2.2065 1.4247 1.9339 2.9201 2.5609 2.8815 2.9028 2.4279 2.6768
Actin 0.0003 0.0002 0.0002 0.0008 0.0001 0.0003 0.0323 0.0016 0.0166 0.0032 0.0016 0.0095 0.0023 0.0086 0.0244 0.0281 0.0002 0.0051
Bud 0 0.0001 0.0002 0.0003 0 0.0001 0.001 0.0034 0.0064 0.0002 0.0002 0.0027 0.0009 0.0005 0.0017 0.0031 0 0.0019
Bud Neck 0.0001 0.0001 0.001 0.0005 0.0002 0.0018 0.0052 0.0008 0.0014 0.0001 0.0002 0.0069 0.0003 0.0001 0.0004 0.0006 0.0001 0.0008
Bud Periphery 0.0001 0.0003 0.0005 0.0005 0 0.0004 0.0023 0.0007 0.0145 0.0001 0.0002 0.0064 0.0022 0.0007 0.0036 0.0035 0 0.0037
Bud Site 0.0001 0.0009 0.0041 0.0006 0 0.0001 0.0188 0.0171 0.0261 0.001 0.0003 0.0014 0.003 0.0037 0.0035 0.0054 0 0.0002
Cell Periphery 0.0007 0.0028 0.0038 0.0007 0.0002 0.0011 0.0012 0.0005 0.001 0.0001 0.0001 0.0004 0.0006 0.0003 0.0004 0.0004 0.0001 0.0002
Cytoplasm 0.5132 0.7929 0.7627 0.7717 0.7933 0.8471 0.2366 0.438 0.3448 0.4097 0.4715 0.5643 0.2319 0.4249 0.2928 0.3678 0.1941 0.3884
Cytoplasmic Foci 0.0037 0.0025 0.0028 0.0046 0.0031 0.0039 0.044 0.0161 0.0116 0.0259 0.0054 0.01 0.0174 0.004 0.0155 0.0213 0.0026 0.0117
Eisosomes 0.0001 0.0001 0.0001 0.0001 0 0 0.0003 0.0001 0.0002 0 0.0001 0.0002 0.0002 0.0003 0.0002 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.0038 0.003 0.0034 0.0047 0.0036 0.0021 0.0068 0.001 0.0098 0.0011 0.0017 0.0017 0.0065 0.0008 0.0019 0.0065 0.0008 0.0016
Endosome 0.0012 0.0008 0.0011 0.0024 0.0028 0.0026 0.041 0.0011 0.0069 0.0079 0.0134 0.0105 0.042 0.0015 0.0098 0.0219 0.0003 0.01
Golgi 0.0002 0.0001 0.0001 0.0003 0.0001 0.0001 0.0119 0.0003 0.0025 0.0037 0.0006 0.0024 0.017 0.0018 0.0149 0.0177 0.0001 0.0035
Lipid Particles 0.0003 0.0002 0.0002 0.0004 0 0.0001 0.0427 0.0002 0.0006 0.0049 0.0012 0.0016 0.0053 0.0002 0.0145 0.0027 0.0001 0.0009
Mitochondria 0.0006 0.0001 0.0001 0.0002 0.0001 0.0001 0.0174 0.0026 0.012 0.0004 0.0009 0.0078 0.0054 0.0147 0.004 0.0053 0.0001 0.0094
None 0.4728 0.1933 0.2171 0.2081 0.1947 0.1391 0.4449 0.5131 0.5304 0.5327 0.4378 0.3656 0.6246 0.5358 0.6005 0.5003 0.8006 0.5511
Nuclear Periphery 0.0003 0.0003 0.0003 0.0006 0.0003 0.0001 0.0255 0.0002 0.0007 0.0003 0.0344 0.0009 0.0098 0.0002 0.0005 0.0014 0.0001 0.0028
Nucleolus 0 0.0001 0.0001 0.0001 0 0 0.0011 0.0007 0.0003 0 0.0009 0.0003 0.0007 0.0001 0.0002 0.0001 0 0.0004
Nucleus 0.0004 0.0005 0.0006 0.0008 0.0004 0.0003 0.0109 0.0008 0.0008 0.0003 0.0086 0.0009 0.0142 0.0004 0.0006 0.0008 0.0001 0.0019
Peroxisomes 0 0 0 0.0001 0 0 0.0228 0.0005 0.0014 0.0069 0.0006 0.0023 0.0015 0.0009 0.009 0.0098 0 0.0006
Punctate Nuclear 0.0001 0.0001 0.0001 0.0003 0.0001 0.0001 0.0283 0.0005 0.002 0.0007 0.0181 0.0014 0.0019 0.0001 0.0009 0.0013 0.0001 0.0042
Vacuole 0.0018 0.0016 0.0016 0.0021 0.0009 0.0006 0.0033 0.0008 0.0086 0.0006 0.0012 0.0021 0.0098 0.0005 0.0007 0.0013 0.0002 0.0011
Vacuole Periphery 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0.0016 0.0001 0.0016 0.0001 0.0011 0.0006 0.0024 0.0001 0.0002 0.0005 0 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 25.9555 14.7653 17.413 28.115 18.1647 21.8141 25.5263 27.3497 29.1162 28.0219
Translational Efficiency 0.4514 0.6005 0.474 0.3821 0.5223 0.8319 0.422 0.512 0.482 0.4404

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2108 98 162 1357 2147 1505 1016 116 4255 1603 1178 1473

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 652.62 764.09 1161.34 851.49 675.59 750.26 888.78 901.06 664.21 751.11 926.26 855.39
Standard Deviation 71.54 90.48 129.52 108.97 95.60 97.22 101.48 113.64 85.31 96.88 141.42 110.16
Intensity Change Log 2 — 0.227499 0.831475 0.383746 — 0.151243 0.395678 0.415475 — 0.189215 0.626225 0.399972

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000064 0.000462 0.000747 0.000710 0.000164 0.000316 0.000124 0.000165 0.000115 0.000325 0.000210 0.000667
Bud Neck 0.006513 0.016036 0.001607 0.005023 0.019414 0.036339 0.001447 0.002526 0.013022 0.035098 0.001469 0.004827
Bud Site 0.003914 0.018798 0.014242 0.033153 0.004937 0.024710 0.004285 0.006912 0.004430 0.024348 0.005654 0.031087
Cell Periphery 0.000145 0.000122 0.000331 0.000147 0.000111 0.000163 0.000141 0.000106 0.000128 0.000160 0.000167 0.000143
Cytoplasm 0.662118* 0.352813* 0.493669* 0.529380* 0.513040* 0.469045* 0.580906* 0.446517* 0.586896* 0.461939* 0.568909* 0.522854*
Cytoplasmic Foci 0.123714 0.358882* 0.056374 0.034808 0.230475* 0.221849* 0.023705 0.039758 0.177584 0.230227* 0.028198 0.035198
Eisosomes 0.000119 0.000171 0.000083 0.000054 0.000203 0.000153 0.000051 0.000070 0.000161 0.000154 0.000055 0.000056
Endoplasmic Reticulum 0.000249 0.000890 0.003269 0.001169 0.001173 0.000542 0.001546 0.002496 0.000715 0.000563 0.001783 0.001273
Endosome 0.003035 0.039569 0.015408 0.012154 0.012693 0.033921 0.003158 0.022242 0.007908 0.034266 0.004843 0.012949
Golgi 0.000715 0.005394 0.000307 0.005365 0.003609 0.006508 0.000071 0.008094 0.002176 0.006440 0.000103 0.005580
Lipid Particles 0.002307 0.009436 0.003542 0.001058 0.008564 0.005728 0.001315 0.001450 0.005464 0.005955 0.001622 0.001089
Mitochondria 0.000616 0.010839 0.000086 0.007680 0.003436 0.010633 0.000203 0.000418 0.002039 0.010646 0.000187 0.007109
Mitotic Spindle 0.000351 0.001130 0.003769 0.041377 0.002150 0.010156 0.002554 0.004562 0.001259 0.009604 0.002721 0.038478
None 0.007861 0.001258 0.000833 0.001509 0.002330 0.002020 0.004066 0.001419 0.005070 0.001973 0.003621 0.001502
Nuclear Periphery 0.000121 0.000376 0.000827 0.000896 0.000394 0.000249 0.000968 0.001052 0.000258 0.000257 0.000949 0.000908
Nuclear Periphery Foci 0.000210 0.001016 0.014702 0.001112 0.000299 0.000239 0.001572 0.001975 0.000255 0.000286 0.003377 0.001180
Nucleolus 0.000734 0.000917 0.000227 0.000229 0.001085 0.001369 0.000235 0.000125 0.000911 0.001341 0.000234 0.000221
Nucleus 0.151927* 0.044140 0.057843 0.095455 0.122920 0.058124 0.255867* 0.154026* 0.137291* 0.057269 0.228635* 0.100067
Peroxisomes 0.001137 0.033162 0.000382 0.002642 0.005922 0.010162 0.000655 0.000293 0.003551 0.011568 0.000617 0.002457
Vacuole 0.033907 0.102190 0.331353* 0.223147* 0.066049 0.105182 0.117011 0.302606* 0.050125 0.104999 0.146487 0.229405*
Vacuole Periphery 0.000244 0.002401 0.000396 0.002933 0.001033 0.002594 0.000121 0.003187 0.000642 0.002582 0.000159 0.002953

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.14 -3.66 -4.17 0.22 1.22 -2.90 -0.96 -2.64 0.94 -2.09 -4.35 -4.88 -3.71 -0.89 -1.93
Bud Neck -3.42 7.30 3.23 4.38 -6.84 -7.30 16.93 13.99 15.54 -2.11 -10.78 17.77 13.04 15.72 -6.60
Bud Site -2.89 -2.47 -7.02 -0.08 -1.89 -9.30 1.10 -1.18 6.28 -1.60 -9.88 -0.71 -7.03 2.48 -6.33
Cell Periphery 1.42 -2.82 3.10 1.72 4.09 -3.17 -2.95 0.53 3.03 2.26 -1.90 -2.15 3.18 3.85 5.28
Cytoplasm 11.60 12.31 25.19 -2.90 -1.63 4.69 3.81 7.67 5.91 5.94 15.46 13.79 19.25 3.81 3.53
Cytoplasmic Foci -9.86 15.05 30.87 14.31 4.80 1.33 45.93 35.33 30.34 -2.21 -8.77 50.67 50.66 38.75 -0.52
Eisosomes -2.17 3.46 8.83 5.26 4.93 3.54 10.85 8.81 7.27 -2.17 0.87 12.28 14.08 12.93 3.64
Endoplasmic Reticulum -1.34 -7.88 -12.47 -0.87 5.37 2.50 -4.82 -3.35 -5.46 -0.39 1.00 -10.62 -4.89 -6.94 7.92
Endosome -4.45 -7.30 -2.82 4.15 4.92 -10.73 12.84 1.66 6.70 -1.00 -14.37 7.49 2.96 14.83 -1.31
Golgi -2.84 5.01 -1.91 2.02 -2.75 -3.95 11.30 1.27 2.90 -1.01 -6.57 12.59 0.69 5.62 -3.20
Lipid Particles -1.54 -1.92 4.65 1.82 5.44 3.22 11.11 10.27 5.76 -1.41 -0.56 10.41 12.39 7.15 5.91
Mitochondria -2.22 13.43 -2.34 1.70 -2.92 -4.82 10.70 10.54 7.16 0.21 -6.12 11.86 -0.62 4.90 -2.78
Mitotic Spindle -1.92 -1.17 -7.67 -7.33 -3.85 -4.14 -1.54 -1.79 -0.94 -1.50 -4.88 -2.40 -7.50 -3.78 -5.56
None 7.24 9.78 7.80 -1.26 -7.21 0.55 -2.98 -0.46 -0.73 0.96 5.35 3.99 7.07 -0.17 3.41
Nuclear Periphery -1.51 -11.52 -19.02 -4.64 -3.48 2.19 -14.24 -7.10 -8.58 0.44 -0.07 -21.90 -16.50 -15.97 0.18
Nuclear Periphery Foci -1.24 -12.48 -8.35 -0.04 11.79 1.63 -11.49 -6.35 -6.59 -0.85 -0.55 -14.25 -9.13 -8.06 10.19
Nucleolus -0.63 3.00 2.86 2.50 -0.93 -0.90 6.05 6.54 4.97 2.51 -1.58 6.04 6.04 4.88 -0.11
Nucleus 7.65 15.40 6.95 -4.90 -8.95 17.93 -19.79 -0.90 -4.81 8.11 26.01 -15.97 4.11 -14.05 16.88
Peroxisomes -4.49 4.46 0.37 4.51 -1.70 -4.25 9.25 10.09 11.76 0.53 -8.36 9.07 5.48 10.82 -1.45
Vacuole -5.64 -18.70 -39.43 -16.26 3.43 -9.49 -16.86 -13.57 -12.15 -8.98 -15.00 -23.75 -39.71 -30.17 -12.95
Vacuole Periphery -2.83 -1.77 -2.74 1.57 -2.46 -5.87 9.98 0.59 2.95 -0.97 -7.97 10.34 -1.38 4.19 -3.22
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; required for proliferation or remodeling of the ER that is caused by overexpression of Hmg2p; may interact with ribosomes, based on co-purification experiments; HER1 has a paralog, GIP3, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (45%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Her1

Her1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Her1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available