Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L33B; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable; homologous to mammalian ribosomal protein L35A, no bacterial homolog; RPL33B has a paralog, RPL33A, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0.07 0.08 0.07 0.1 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0.05 0.06 0.06 0.08 0.06 0.06 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.0 0.98 0.99 0.98 0.91 0.91 0.75 0.73 0.75 0.61 0.68 0.6 0.96 0.99 0.97 1.0 1.0 0.98 0.97 0.95 0.93 0.89 0.91 0.88
Endoplasmic Reticulum 0 0 0 0 0.1 0.07 0.19 0.2 0.17 0.2 0.17 0.18 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0.05 0.06 0 0.08 0 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0.06 0 0.06 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0.06 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 2 10 16 37 39 29 47 0 0 0 0 0 0 0 0 0 0 1 0
Bud 0 0 2 2 0 0 1 0 3 4 3 3 1 0 0 0 0 0 0 1 1 3 3 5
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 1 4 5 19 28 44 42 45 31 26 46 0 1 10 0 2 0 0 0 0 0 0 0
Cytoplasm 248 326 416 474 599 536 539 487 424 307 280 294 130 241 307 155 94 107 239 320 384 117 280 242
Endoplasmic Reticulum 0 7 6 7 68 39 138 131 93 102 68 88 6 4 4 6 4 3 3 2 11 1 5 8
Endosome 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 1 0 0 0 1 0 0
Golgi 0 0 0 1 1 4 36 40 16 41 15 46 1 0 2 0 1 1 0 0 0 0 2 1
Mitochondria 0 0 0 0 0 0 1 3 32 13 23 37 0 0 1 3 0 0 0 1 1 3 5 5
Nucleus 0 0 0 0 0 1 1 2 1 3 1 0 0 0 0 0 0 0 0 2 0 0 2 1
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 1 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
SpindlePole 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 2 1 1 3 4 9 1 30 23 13 0 0 1 0 1 0 0 5 2 1 1 2
Unique Cell Count 249 331 421 483 659 591 718 666 562 505 410 490 135 244 315 155 94 109 246 338 412 132 307 274
Labelled Cell Count 251 334 430 490 688 613 774 731 652 573 469 578 138 246 326 164 102 112 246 338 412 132 307 274


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 92.5 84.1 81.5 76.0 58.7 44.3 35.2 31.3 26.6 22.9 21.0 22.0 81.1 71.3 67.1 68.5 85.3 112.5 74.5 83.7 83.1
Std Deviation (1e-4) 16.1 20.1 17.6 13.5 10.3 7.9 7.4 6.6 5.7 6.3 5.9 5.0 22.2 18.4 18.2 26.2 34.5 33.0 28.9 29.6 31.9
Intensity Change (Log2) – – – -0.1 -0.47 -0.88 -1.21 -1.38 -1.61 -1.83 -1.96 -1.89 -0.01 -0.19 -0.28 -0.25 0.07 0.46 -0.13 0.04 0.03


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 3.2 5.4 5.8 5.6 6.5 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 2.1 3.4 4.2 4.3 5.0 4.1 4.2 5.6 0 0 2.2 0 0 0
Cytoplasm -0.8 -5.3 -5.4 -10.5 -11.0 -10.3 -13.9 -11.9 -14.1 -1.9 0 -1.4 1.4 1.1 -0.5
Endoplasmic Reticulum 0 5.6 3.9 8.7 8.8 7.8 8.9 7.7 8.2 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 4.7 5.1 3.5 6.0 4.0 6.5 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 5.0 3.3 4.9 5.8 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 4.5 4.3 2.6 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 75.6942 104.8212 94.4102 79.9822 77.2264 76.1894 84.1029 113.0717 103.2987 101.1302 87.1415 97.6812 85.898 114.1013 102.7388 100.338 78.7856 101.4152
Actin 0.0119 0.0004 0.018 0.0267 0.0007 0.0001 0.0175 0.0002 0.0004 0.0002 0.0005 0.0009 0.024 0.0007 0.0023 0.0005 0.0006 0.0016
Bud 0.003 0.0005 0.0021 0.0019 0.0019 0.0001 0.0034 0.0002 0.0015 0.0006 0.0016 0.0003 0.0022 0.0003 0.0008 0.0019 0.0006 0.0006
Bud Neck 0.0009 0.0004 0.0006 0.0008 0.0021 0.0008 0.0008 0.0002 0.0004 0.0005 0.0006 0.0005 0.0009 0.0002 0.0006 0.0007 0.0004 0.0011
Bud Periphery 0.009 0.0003 0.0018 0.0009 0.0009 0 0.0032 0.0001 0.0015 0.0001 0.0007 0.0002 0.0025 0.0002 0.0004 0.0009 0.0003 0.0002
Bud Site 0.0022 0.0002 0.0028 0.0012 0.001 0 0.0015 0.0001 0.0003 0 0.0008 0.0004 0.0009 0.0004 0.0004 0.0003 0.0003 0.0001
Cell Periphery 0.0167 0.0057 0.0031 0.0026 0.0042 0 0.0044 0.0007 0.0013 0.0005 0.0014 0.0003 0.0054 0.0013 0.0041 0.0065 0.0017 0.0004
Cytoplasm 0.6016 0.94 0.838 0.5125 0.7495 0.9776 0.7691 0.9855 0.9209 0.9116 0.7296 0.9018 0.7267 0.9748 0.9028 0.8171 0.849 0.9026
Cytoplasmic Foci 0.0166 0.0007 0.0084 0.0152 0.0064 0.0036 0.0162 0.0007 0.0046 0.0016 0.0464 0.0132 0.005 0.0007 0.0064 0.0027 0.007 0.0023
Eisosomes 0.0005 0 0.0006 0.0004 0.0003 0 0.0002 0 0.0001 0 0.0002 0.0011 0.0002 0.0001 0.0002 0 0.0002 0
Endoplasmic Reticulum 0.0647 0.0166 0.0075 0.0053 0.0043 0.0025 0.0306 0.0026 0.0108 0.0078 0.0284 0.0136 0.0391 0.0051 0.007 0.0055 0.0041 0.0641
Endosome 0.0238 0.0012 0.0073 0.0242 0.0254 0.0066 0.0158 0.001 0.0063 0.007 0.0129 0.0102 0.0059 0.0012 0.0035 0.0062 0.0166 0.0053
Golgi 0.0068 0.0002 0.004 0.0102 0.0009 0.0004 0.0031 0.0001 0.0006 0.0004 0.0006 0.0009 0.0015 0.0003 0.0007 0.0004 0.0098 0.0007
Lipid Particles 0.0065 0.0001 0.0039 0.0181 0.0012 0 0.0048 0.0001 0.0012 0.0002 0.0048 0.0046 0.0018 0.0003 0.0026 0.0015 0.0088 0.0001
Mitochondria 0.0156 0.0003 0.0088 0.0309 0.0066 0.0001 0.0078 0.0001 0.0043 0.0002 0.0162 0.037 0.0056 0.0004 0.0078 0.0057 0.0294 0.0007
None 0.0054 0.0001 0.0039 0.0041 0.0037 0.0001 0.0094 0.0001 0.0046 0.0002 0.0288 0.003 0.0039 0.0002 0.0051 0.0009 0.003 0.0003
Nuclear Periphery 0.0433 0.0087 0.011 0.0117 0.0136 0.0012 0.0278 0.001 0.004 0.0097 0.0052 0.001 0.0314 0.0034 0.0054 0.0075 0.0044 0.0107
Nucleolus 0.0082 0 0.0022 0.0008 0.0224 0 0.0019 0 0.0009 0 0.0069 0.0024 0.0052 0.0002 0.0035 0.0015 0.0127 0
Nucleus 0.0128 0.0015 0.0045 0.0047 0.0115 0.0009 0.0084 0.0007 0.0022 0.0026 0.0047 0.001 0.0134 0.0014 0.0038 0.0052 0.0084 0.0021
Peroxisomes 0.0015 0 0.0066 0.0111 0.0003 0 0.0011 0 0.0002 0 0.0017 0.0025 0.0022 0 0.0004 0.0002 0.0016 0
Punctate Nuclear 0.0029 0 0.0007 0.0018 0.0003 0 0.0065 0 0.0004 0 0.0027 0.0002 0.0019 0 0.0003 0.0001 0.0002 0.0001
Vacuole 0.1047 0.0195 0.049 0.2148 0.0979 0.0037 0.051 0.006 0.0273 0.0458 0.0733 0.0029 0.0975 0.0077 0.0342 0.1091 0.0319 0.0049
Vacuole Periphery 0.0415 0.0035 0.0151 0.1001 0.0449 0.0022 0.0154 0.0007 0.006 0.0111 0.032 0.0019 0.0227 0.001 0.0078 0.0252 0.009 0.0021

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 955.2622 974.1987 903.6218 1027.4148 993.4806 701.1589 778.005 790.5081 720.6267 857.8483
Translational Efficiency 2.0644 2.1278 2.3674 1.6413 2.1434 2.6596 2.2503 2.3597 2.318 2.1013

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
201 1353 2794 1531 2136 2467 3439 1549 2337 3820 6233 3080

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 3904.95 5354.79 8980.79 6447.51 4518.61 5205.48 8282.64 6843.53 4465.83 5258.36 8595.59 6646.68
Standard Deviation 859.22 1160.70 1543.80 2627.80 1066.27 1248.39 1858.01 2573.00 1064.07 1220.15 1758.87 2607.91
Intensity Change Log 2 — 0.455526 1.201538 0.723438 — 0.204152 0.874212 0.598862 — 0.326145 1.035217 0.657952

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000141 0.000059 0.000062 0.000434 0.000038 0.000041 0.000038 0.000228 0.000046 0.000048 0.000049 0.000330
Bud Neck 0.000801 0.000517 0.000345 0.002615 0.000131 0.000252 0.000292 0.001606 0.000188 0.000346 0.000316 0.002108
Bud Site 0.008980 0.003298 0.002284 0.016884 0.001308 0.001774 0.003746 0.011494 0.001968 0.002314 0.003090 0.014173
Cell Periphery 0.032355 0.013000 0.019901 0.045868 0.008178 0.003475 0.005529 0.030366 0.010257 0.006849 0.011971 0.038071
Cytoplasm 0.328712* 0.720603* 0.748081* 0.609340* 0.731394* 0.814002* 0.754984* 0.685267* 0.696760* 0.780921* 0.751890* 0.647526*
Cytoplasmic Foci 0.023163 0.009995 0.003558 0.011926 0.009395 0.007233 0.003567 0.010024 0.010579 0.008211 0.003563 0.010969
Eisosomes 0.000003 0.000001 0.000001 0.000008 0.000001 0.000001 0.000001 0.000003 0.000001 0.000001 0.000001 0.000005
Endoplasmic Reticulum 0.002321 0.001292 0.001232 0.001016 0.002041 0.000699 0.000595 0.000362 0.002065 0.000909 0.000881 0.000687
Endosome 0.002569 0.000712 0.000429 0.001207 0.000636 0.000618 0.000463 0.000548 0.000802 0.000651 0.000448 0.000876
Golgi 0.284846* 0.069665 0.016119 0.012388 0.048154 0.035786 0.007332 0.013550 0.068511 0.047786 0.011271 0.012972
Lipid Particles 0.023904 0.013679 0.015672 0.028923 0.006547 0.004400 0.004208 0.019597 0.008040 0.007687 0.009347 0.024232
Mitochondria 0.000234 0.000162 0.000244 0.001313 0.000217 0.000233 0.000303 0.000339 0.000219 0.000208 0.000277 0.000823
Mitotic Spindle 0.002749 0.001122 0.000364 0.013673 0.000502 0.001046 0.000290 0.005382 0.000695 0.001073 0.000323 0.009503
None 0.001504 0.001633 0.000694 0.002817 0.002679 0.002580 0.000603 0.001724 0.002578 0.002245 0.000644 0.002267
Nuclear Periphery 0.000678 0.000657 0.000459 0.000535 0.000416 0.000299 0.000102 0.000454 0.000438 0.000426 0.000262 0.000494
Nuclear Periphery Foci 0.019989 0.016928 0.006236 0.007429 0.010816 0.010124 0.002181 0.006883 0.011605 0.012534 0.003999 0.007155
Nucleolus 0.000144 0.000065 0.000071 0.000260 0.000068 0.000097 0.000122 0.000182 0.000075 0.000086 0.000099 0.000221
Nucleus 0.002739 0.005012 0.003958 0.017245 0.002545 0.005226 0.003485 0.017822 0.002562 0.005150 0.003697 0.017535
Peroxisomes 0.000034 0.000031 0.000073 0.000169 0.000026 0.000016 0.000093 0.000113 0.000027 0.000021 0.000084 0.000141
Vacuole 0.081306 0.074282 0.135873 0.200048* 0.060628 0.055283 0.171080 0.169824 0.062406 0.062012 0.155298 0.184847
Vacuole Periphery 0.182825* 0.067287 0.044344 0.025901 0.114283* 0.056815 0.040985 0.024232 0.120178* 0.060524 0.042491 0.025062

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.60 2.29 -5.05 -6.75 -6.60 -0.31 -0.95 -5.86 -5.84 -5.75 -0.10 -1.24 -8.87 -8.95 -8.75
Bud Neck 1.07 1.49 -8.20 -10.45 -10.76 -1.94 -5.37 -9.97 -9.46 -9.02 -3.24 -5.45 -15.04 -14.22 -13.99
Bud Site 2.72 3.17 -5.53 -11.55 -12.35 -2.34 -9.18 -11.30 -10.91 -8.93 -1.18 -5.21 -16.42 -16.12 -15.10
Cell Periphery 4.34 2.76 -0.98 -10.78 -7.56 8.03 4.57 -10.91 -14.36 -13.05 4.84 -2.30 -14.73 -18.33 -14.25
Cytoplasm -15.81 -17.32 -9.75 12.00 16.22 -9.77 -2.20 8.21 17.10 10.93 -10.19 -6.37 9.89 22.43 19.39
Cytoplasmic Foci 4.82 7.50 -1.13 -7.17 -10.38 2.93 9.64 -6.69 -7.74 -9.56 3.26 11.78 -9.15 -10.85 -14.12
Eisosomes 2.93 2.62 -2.88 -4.46 -4.32 1.82 -0.94 -9.03 -9.86 -8.61 1.35 -1.49 -6.55 -6.81 -6.33
Endoplasmic Reticulum 1.63 2.28 2.75 0.90 1.45 8.03 9.26 10.90 5.00 5.13 5.40 7.88 7.65 1.62 2.15
Endosome 6.92 8.00 3.91 -4.19 -6.05 0.26 3.60 -2.08 -2.26 -5.47 2.73 7.25 -2.93 -4.86 -7.49
Golgi 13.22 16.78 17.11 19.84 6.37 5.39 22.47 18.72 14.92 -6.91 7.11 22.36 22.06 24.53 -0.53
Lipid Particles 2.90 2.29 -2.11 -8.50 -7.81 3.66 3.81 -10.68 -12.31 -12.38 0.43 -2.45 -14.83 -15.53 -14.19
Mitochondria 0.64 -0.20 -1.54 -1.68 -1.53 -0.36 -3.60 -2.16 -1.79 -1.13 0.26 -2.73 -1.89 -1.92 -1.67
Mitotic Spindle 4.90 7.64 -8.61 -9.13 -9.37 -1.92 0.19 -6.92 -6.57 -6.92 -1.99 2.54 -11.43 -11.17 -11.56
None -0.86 5.93 -2.49 -2.26 -4.26 0.13 3.33 1.15 1.19 -6.13 0.52 3.41 0.42 -0.19 -6.45
Nuclear Periphery 0.08 2.46 -0.41 -0.61 -3.78 2.67 11.59 -5.04 -6.70 -13.76 0.12 5.45 -6.30 -6.02 -11.76
Nuclear Periphery Foci 1.35 7.16 5.45 6.42 -3.35 0.72 13.25 2.13 1.48 -10.70 -1.31 11.99 3.37 5.14 -9.77
Nucleolus 0.98 0.87 -1.77 -6.98 -6.75 -0.95 -4.53 -6.88 -4.11 -5.10 -0.52 -2.16 -8.36 -6.80 -8.33
Nucleus -3.45 -2.70 -13.16 -12.23 -12.55 -5.35 -5.20 -15.82 -13.31 -14.19 -6.99 -6.53 -20.72 -17.81 -18.75
Peroxisomes 0.31 -3.22 -5.84 -6.49 -4.48 2.24 -9.28 -5.60 -6.34 -1.60 1.30 -10.00 -8.60 -9.22 -4.42
Vacuole 0.71 -6.66 -11.48 -17.73 -7.98 1.41 -26.05 -18.45 -19.22 0.33 -0.16 -28.05 -26.34 -27.01 -5.11
Vacuole Periphery 8.22 10.06 11.76 13.98 12.49 13.75 19.78 25.11 14.61 12.19* 15.25 21.73 27.78 20.09 17.41
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L33B; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable; homologous to mammalian ribosomal protein L35A, no bacterial homolog; RPL33B has a paralog, RPL33A, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-2

Rpl33b

Rpl33b


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl33b-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available