Standard name
Human Ortholog
Description Putative protein; predicted to be an alpha-isopropylmalate carrier; belongs to the sideroblastic-associated protein family; non-tagged protein is detected in purified mitochondria; likely to play a role in iron homeostasis
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0.08 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.12 0.05 0.07 0 0 0 0 0 0
Cytoplasm 0 0.06 0 0.05 0 0.05 0 0 0 0 0 0 0 0 0.06 0.09 0.06 0.06 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.06 0.05 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0.07 0 0 0 0
Golgi 0 0.06 0 0 0 0 0 0 0 0 0 0 0.09 0.22 0.32 0.35 0.35 0.38 0.05 0.05 0.05 0 0.06 0.05
Mitochondria 0.88 0.86 0.97 0.94 0.9 0.89 0.91 0.9 0.93 0.92 0.95 0.97 0.79 0.7 0.59 0.09 0.05 0.09 0.81 0.72 0.82 0.8 0.72 0.62
Nucleus 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0.05 0 0.06 0.09 0.06 0.06 0 0 0 0 0 0.11 0.05 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0.05 0.09 0.08 0.06 0.05 0 0.06 0 0 0 0 0.06 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.11 0.19 0 0.06 0.1 0.06 0.06 0 0 0.07 0 0 0.12 0.16 0.21 0.28 0.27 0.26 0 0.08 0 0 0.1 0.17
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 1 0 0 0 0 0 0 0 0 0 4 7 4 2 2 8 1 3 1 0 4 4
Bud 4 3 1 3 15 12 17 18 13 21 11 20 0 3 5 2 5 1 0 0 0 0 1 4
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1
Bud Site 1 0 1 0 2 9 15 9 3 10 7 14 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 2 4 10 10 2 1 1 2 3 2 5 2 10 7 10 4 7 0 1 0 0 0 0
Cytoplasm 7 8 2 14 18 23 20 31 16 20 18 6 1 11 18 7 5 6 1 1 0 0 1 0
Endoplasmic Reticulum 2 3 3 3 4 5 2 1 1 3 6 1 5 17 15 3 2 2 1 0 0 0 2 3
Endosome 6 1 0 1 12 1 1 1 3 3 1 0 0 10 14 2 2 2 6 11 2 4 8 10
Golgi 2 9 0 2 0 0 0 0 0 0 0 0 5 62 88 28 28 37 10 7 5 2 15 13
Mitochondria 165 123 117 271 412 390 552 662 451 660 401 575 45 197 163 7 4 9 152 111 97 102 182 154
Nucleus 4 2 1 1 5 14 37 25 12 10 5 13 1 1 0 1 2 3 0 0 0 1 2 1
Nuclear Periphery 3 0 2 5 7 23 25 47 46 42 26 21 0 5 1 0 9 5 1 0 1 1 0 1
Nucleolus 8 3 2 4 13 21 56 57 28 38 17 34 0 1 1 3 5 3 1 0 0 0 0 1
Peroxisomes 3 1 0 4 10 0 8 6 3 8 3 4 0 7 9 3 3 6 4 2 3 5 4 6
SpindlePole 4 1 1 2 7 2 19 19 11 28 8 11 0 5 2 0 0 1 2 0 0 0 2 2
Vac/Vac Membrane 20 27 4 16 46 28 37 32 18 48 16 12 7 44 57 23 21 25 3 12 1 5 24 42
Unique Cell Count 188 143 121 288 458 437 606 738 486 715 424 592 57 283 278 81 79 98 189 154 120 128 253 251
Labelled Cell Count 232 184 139 336 561 530 790 909 607 894 521 716 70 380 384 91 92 115 189 154 120 128 253 251


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.1 6.0 4.6 5.2 5.2 4.8 4.2 4.3 4.3 4.0 4.1 4.0 7.0 7.1 7.2 11.1 12.2 12.5 7.1 8.0 8.1
Std Deviation (1e-4) 1.0 0.9 0.9 1.3 1.3 1.7 1.3 1.6 1.7 1.2 1.3 1.1 1.1 1.0 1.1 2.7 2.7 3.2 1.0 1.5 1.8
Intensity Change (Log2) – – – 0.18 0.17 0.08 -0.14 -0.09 -0.1 -0.18 -0.16 -0.19 0.61 0.64 0.65 1.28 1.41 1.45 0.63 0.8 0.81


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud 0 0 0 0 0 – 0 – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 – – 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 – – 0 0 0 2.5 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum 0 0 0 0 0 – 0 – – 0 1.5 1.3 0 0 0
Endosome 0 0 0 0 0 – 0 – – 0 0 0 0 0 0
Golgi 0 0 0 0 0 – 0 – – 0 5.6 7.0 7.0 7.1 7.4
Mitochondria -1.1 -2.3 0 0 0 – 0 – – -3.9 -6.0 -7.6 -12.6 -13.0 -13.0
Nuclear Periphery 0 0 0 0 0 – 0 – – 0 0 0 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus 0 0 0 0 0 – 0 – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 – – 0 0 0 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches 0 0 0 0 0 – 0 – – 0 0 0 0 0 0
Cytoplasm 0 0 1.7 0 0 – 0 – – 0 0 2.0 0 0 0
Nucleus 0 0 0 2.4 0 – 0 – – 0 0 0 0 0 0
Vacuole 1.0 2.3 1.3 1.2 0.5 – 1.4 – – 0 3.5 4.4 5.1 4.9 4.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.1498 7.1188 6.6632 6.4802 5.8142 7.04 6.9554 8.6277 7.7512 7.5501 6.4801 7.7888 6.0834 7.0469 6.2733 6.6831 4.8691 6.7203
Actin 0.0198 0.0104 0.0071 0.0011 0.0255 0.001 0.0042 0.0059 0.0012 0.0001 0.0013 0.0048 0.0069 0.0036 0.015 0.0344 0.0419 0.0001
Bud 0.0011 0.0043 0.0022 0.0013 0.0006 0.001 0.0003 0.0004 0.0001 0 0.0001 0.0001 0.0001 0.0003 0.001 0.0003 0.0006 0
Bud Neck 0.0005 0.0004 0.0006 0.0002 0.0004 0.0001 0.0001 0.0002 0 0 0 0 0.0004 0.0002 0.0005 0.0001 0.0007 0
Bud Periphery 0.0029 0.0097 0.0057 0.0011 0.0011 0.002 0.0007 0.0004 0.0001 0.0001 0.0003 0.0001 0.0002 0.0004 0.0014 0.0006 0.001 0.0001
Bud Site 0.0037 0.0138 0.0076 0.0005 0.0013 0.0001 0.0006 0.001 0.0001 0 0.0001 0.0002 0.0007 0.0011 0.002 0.0007 0.0015 0
Cell Periphery 0.0003 0.0005 0.0003 0.0004 0.0002 0.0002 0.0003 0.0001 0.0001 0 0.0001 0 0.0002 0.0002 0.0005 0.0001 0.0001 0
Cytoplasm 0.0018 0.0008 0.0011 0.0002 0.0064 0.0013 0.0007 0.0004 0.0008 0 0 0.0003 0.0037 0.0004 0 0.0005 0.0005 0
Cytoplasmic Foci 0.0302 0.0033 0.0075 0.0108 0.0104 0.0025 0.0085 0.0117 0.0004 0 0.0078 0.0053 0.0069 0.0029 0.0006 0.0103 0.0101 0
Eisosomes 0.0005 0.0002 0.0002 0.0002 0.0003 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0002 0.0001 0.0003 0.0003 0.0003 0
Endoplasmic Reticulum 0.0007 0.0002 0.0003 0.0001 0.0013 0.0001 0.0013 0.0001 0.0002 0 0.0001 0.0001 0.0025 0.0001 0 0.0007 0.0012 0
Endosome 0.0322 0.013 0.0156 0.0128 0.0543 0.0041 0.0129 0.0273 0.0015 0.0001 0.0056 0.0042 0.0097 0.0113 0.0012 0.0089 0.0223 0.0003
Golgi 0.0306 0.0285 0.0179 0.0099 0.0293 0.0161 0.0095 0.0124 0.004 0.0002 0.0367 0.0114 0.0107 0.0188 0.0028 0.0074 0.0193 0.0012
Lipid Particles 0.0319 0.0026 0.0069 0.0205 0.008 0.0024 0.0338 0.0027 0.0009 0.0002 0.0365 0.0014 0.0244 0.0093 0.0052 0.0222 0.0261 0.0001
Mitochondria 0.7926 0.8844 0.897 0.9207 0.834 0.9466 0.8911 0.9231 0.9715 0.9985 0.8961 0.9626 0.8906 0.926 0.9541 0.8854 0.8511 0.9964
None 0.0102 0.005 0.0105 0.0006 0.0126 0.011 0.0003 0 0.0134 0 0 0.0001 0.0066 0 0.0001 0.0032 0.001 0
Nuclear Periphery 0.0015 0.0004 0.0004 0.0002 0.0005 0.0001 0.0015 0 0.0001 0 0.0001 0.0002 0.0025 0.0002 0 0.0012 0.0044 0
Nucleolus 0.0008 0.0004 0.0007 0.0043 0.0001 0.0015 0.0004 0.0003 0 0 0.0001 0 0.0008 0.0002 0.0009 0.0002 0.0003 0
Nucleus 0.0004 0.0003 0.0003 0.0005 0.0002 0.0007 0.0004 0.0001 0 0 0 0 0.0024 0.0002 0.0002 0.0002 0.0005 0
Peroxisomes 0.0276 0.0047 0.0093 0.0039 0.0028 0.002 0.0093 0.0093 0.0034 0.0002 0.0127 0.0059 0.0083 0.0107 0.0051 0.0174 0.0115 0.0003
Punctate Nuclear 0.0013 0.0002 0.0007 0.0004 0.001 0.0046 0.0011 0 0 0 0.0004 0.0005 0.0052 0 0 0.0024 0.0041 0
Vacuole 0.0037 0.0087 0.0045 0.0047 0.0039 0.0009 0.0066 0.0028 0.0003 0.0001 0.0008 0.0003 0.0041 0.0071 0.005 0.0008 0.0006 0.0001
Vacuole Periphery 0.0059 0.008 0.0034 0.0054 0.0056 0.0018 0.0164 0.0016 0.0017 0.0003 0.001 0.0024 0.0128 0.0069 0.0038 0.0028 0.0008 0.0012

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 110.4526 106.256 84.7972 87.0924 93.0479 91.8995 73.2283 62.5925 70.8803 77.8589
Translational Efficiency 1.1035 1.3214 1.6001 1.6127 1.6238 1.3249 1.3875 1.8898 1.5595 1.4607

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
795 1434 123 230 1511 872 235 1852 2306 2306 358 2082

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 736.40 873.21 1136.84 1084.55 803.70 868.54 1201.83 1021.07 780.50 871.44 1179.50 1028.08
Standard Deviation 112.39 142.60 121.45 128.56 143.99 134.39 163.87 145.53 137.71 139.57 153.78 145.13
Intensity Change Log 2 — 0.245839 0.626468 0.558535 — 0.111935 0.580504 0.345353 — 0.177514 0.602664 0.451221

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000807 0.003521 0.002713 0.033427 0.001485 0.006441 0.008649 0.007759 0.001251 0.004625 0.006610 0.010595
Bud Neck 0.002730 0.001817 0.007755 0.002179 0.001416 0.001066 0.006103 0.001155 0.001869 0.001533 0.006671 0.001268
Bud Site 0.009955 0.008183 0.026770 0.031586 0.004813 0.004467 0.014368 0.019174 0.006586 0.006778 0.018629 0.020545
Cell Periphery 0.001326 0.000981 0.000557 0.001148 0.000814 0.001106 0.000653 0.001713 0.000991 0.001028 0.000620 0.001650
Cytoplasm 0.002405 0.001795 0.002836 0.005861 0.000755 0.000903 0.001187 0.002541 0.001324 0.001458 0.001754 0.002908
Cytoplasmic Foci 0.020614 0.019057 0.130403 0.052728 0.015947 0.022197 0.053007 0.019574 0.017556 0.020244 0.079598 0.023236
Eisosomes 0.000080 0.000084 0.000084 0.000202 0.000056 0.000089 0.000119 0.000126 0.000064 0.000086 0.000107 0.000134
Endoplasmic Reticulum 0.001768 0.001415 0.007842 0.002074 0.000717 0.000347 0.001467 0.000778 0.001080 0.001011 0.003657 0.000921
Endosome 0.049952 0.043866 0.110007 0.052321 0.037688 0.048084 0.050773 0.025871 0.041916 0.045461 0.071125 0.028793
Golgi 0.061598 0.048248 0.163692* 0.133445* 0.035418 0.048447 0.066962 0.074958 0.044444 0.048323 0.100196 0.081419
Lipid Particles 0.004028 0.002582 0.002220 0.000542 0.005025 0.002672 0.002466 0.000158 0.004681 0.002616 0.002381 0.000201
Mitochondria 0.773443* 0.822755* 0.282830* 0.593513* 0.856314* 0.821838* 0.693650* 0.806741* 0.827744* 0.822408* 0.552503* 0.783185*
Mitotic Spindle 0.004106 0.005263 0.073330 0.029747 0.001839 0.003025 0.026744 0.009154 0.002621 0.004417 0.042750 0.011429
None 0.000505 0.000363 0.000332 0.000299 0.000844 0.000165 0.000522 0.000253 0.000727 0.000288 0.000457 0.000258
Nuclear Periphery 0.000172 0.000149 0.002689 0.000146 0.000185 0.000061 0.000920 0.000046 0.000181 0.000115 0.001528 0.000057
Nuclear Periphery Foci 0.000491 0.000363 0.002940 0.000174 0.000345 0.000141 0.001416 0.000073 0.000395 0.000279 0.001940 0.000084
Nucleolus 0.000671 0.000270 0.001008 0.000038 0.000822 0.000318 0.000203 0.000023 0.000770 0.000288 0.000479 0.000025
Nucleus 0.000410 0.000202 0.002077 0.000128 0.000374 0.000173 0.000208 0.000079 0.000386 0.000191 0.000851 0.000084
Peroxisomes 0.011498 0.014041 0.050350 0.040714 0.013369 0.024443 0.036867 0.012398 0.012724 0.017975 0.041499 0.015527
Vacuole 0.016012 0.011607 0.054414 0.007374 0.007751 0.006536 0.013164 0.006162 0.010599 0.009689 0.027337 0.006296
Vacuole Periphery 0.037429 0.013437 0.075149 0.012353 0.014022 0.007483 0.020551 0.011265 0.022092 0.011185 0.039310 0.011385

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.57 -3.76 -4.44 -4.06 -4.17 -3.19 -3.45 -5.83 -0.72 0.39 -4.75 -3.88 -7.45 -4.22 -2.16
Bud Neck 1.63 -2.44 0.83 -0.73 2.71 0.89 -3.01 0.69 -0.34 3.23 1.00 -3.86 1.86 1.10 4.42
Bud Site 0.86 -2.97 -3.92 -4.32 -0.64 0.29 -2.82 -7.59 -7.44 -1.28 -0.19 -4.06 -7.70 -7.43 -0.57
Cell Periphery 1.13 3.04 0.54 -0.54 -2.29 -0.72 0.85 -2.54 -1.19 -2.88 -0.17 2.43 -2.07 -1.75 -3.25
Cytoplasm 0.58 -0.42 -2.06 -2.67 -1.99 -0.47 -2.40 -7.25 -4.53 -5.23 -0.35 -1.15 -3.95 -3.55 -3.56
Cytoplasmic Foci 0.71 -8.36 -5.29 -5.65 5.45 -2.65 -5.33 -2.00 1.11 4.81 -1.79 -9.26 -3.37 -1.70 8.35
Eisosomes -0.40 -0.37 -4.59 -4.48 -4.37 -3.61 -4.45 -3.29 -1.62 -0.28 -3.31 -4.19 -3.64 -2.44 -1.28
Endoplasmic Reticulum 0.37 -1.22 -0.35 -0.75 1.16 2.47 -1.21 -0.32 -3.36 1.13 0.14 -1.47 0.58 0.20 1.57
Endosome 1.41 -6.29 -0.38 -1.48 5.62 -2.34 -2.09 4.22 5.56 4.16 -1.23 -5.33 5.41 6.58 7.99
Golgi 2.55 -6.52 -5.56 -6.82 1.56 -3.07 -3.71 -9.47 -5.29 -0.90 -1.25 -6.86 -9.18 -8.07 2.19
Lipid Particles 1.19 1.43 3.13 3.69 2.47 1.89 2.11 4.91 3.78 3.28 2.36 2.54 5.95 5.75 4.23
Mitochondria -4.03 15.77 6.79 8.97 -8.11 2.95 6.74 5.37 1.25 -4.68 0.68 12.67 5.16 4.43 -10.48
Mitotic Spindle -0.83 -5.05 -5.94 -5.71 3.05 -2.03 -5.32 -7.56 -5.69 3.70 -2.46 -7.00 -8.48 -6.13 5.40
None 0.97 1.15 1.38 1.40 0.61 1.61 0.79 1.42 -4.43 4.59 1.58 1.00 1.70 1.25 4.68
Nuclear Periphery 0.43 -2.25 0.36 0.03 2.27 1.65 -2.00 1.87 1.20 2.43 1.14 -2.96 2.44 2.07 3.25
Nuclear Periphery Foci 0.61 -1.96 1.92 1.14 2.25 1.43 -1.36 1.98 2.23 1.74 0.81 -2.30 2.94 1.92 2.81
Nucleolus 1.23 -0.53 1.91 2.37 2.60 1.13 1.83 2.40 1.46 3.13 1.78 1.08 3.05 2.64 3.37
Nucleus 1.73 -1.77 2.25 1.21 2.11 1.20 1.28 2.54 0.89 1.66 2.02 -1.37 3.42 1.90 2.36
Peroxisomes -1.15 -3.61 -4.04 -3.70 0.76 -2.99 -3.09 0.44 3.33 3.23 -2.65 -4.63 -1.39 1.15 4.14
Vacuole 2.25 -4.67 4.25 2.57 5.76 0.86 -2.51 1.55 0.27 3.32 0.80 -5.04 4.44 3.37 6.40
Vacuole Periphery 7.99 -3.16 6.67 0.40 5.29 4.83 -1.36 2.00 -3.21 1.95 7.68 -3.22 7.31 -0.19 5.30
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative protein; predicted to be an alpha-isopropylmalate carrier; belongs to the sideroblastic-associated protein family; non-tagged protein is detected in purified mitochondria; likely to play a role in iron homeostasis
Localization
Cell Percentages mitochondrion (95%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Fsf1

Fsf1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Fsf1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available