Standard name
Human Ortholog
Description Member of the ChAPs family (Chs5p-Arf1p-binding proteins); members include Bch1p, Bch2p, Bud7p, and Chs6p; ChAPs family proteins form the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; BUD7 has a paralog, BCH1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.09 0.28 0.1 0.14 0 0 0 0 – 0 0 0 0 0 0.11 – 0 0 0.05 0 0.06 0.07 0.06
Bud 0 0 0.07 0.07 0.05 0 0.06 0.05 0.05 – 0.08 0.06 0.05 0 0 0 – 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 – 0.05 0 0 0 0 0 0
Cytoplasm 0.2 0.29 0.37 0.22 0.29 0.16 0.14 0.17 0.15 – 0.1 0.14 0.12 0.13 0.22 0.47 – 0.5 0 0.09 0 0 0 0
Endoplasmic Reticulum 0.07 0.11 0.14 0 0.05 0.06 0 0 0 – 0 0 0.08 0 0.07 0.11 – 0.05 0 0 0 0 0 0
Endosome 0.15 0 0.09 0.22 0.24 0.14 0.14 0.16 0 – 0 0.13 0.16 0.39 0.19 0.21 – 0.2 0.35 0.25 0.25 0.26 0.23 0.2
Golgi 0.07 0.05 0 0 0 0 0 0 0 – 0 0 0.09 0.09 0.09 0 – 0.05 0.22 0.19 0.11 0.17 0.29 0.39
Mitochondria 0.6 0.6 0.08 0.4 0.23 0.64 0.62 0.49 0.76 – 0.89 0.66 0.63 0.37 0.42 0 – 0.2 0.21 0.28 0.42 0.32 0.25 0.19
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0.08 0 0 – 0 0.05 0 0 0.07 0.05 0.07
SpindlePole 0 0 0.1 0.11 0.16 0.07 0.13 0.19 0.05 – 0 0.09 0 0 0 0.11 – 0 0 0 0 0 0 0
Vac/Vac Membrane 0.05 0 0 0 0 0.05 0.05 0.08 0.05 – 0.05 0.07 0 0.09 0.07 0.16 – 0.15 0 0.06 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 6 6 29 16 32 5 18 12 5 – 1 3 7 1 3 2 – 0 7 5 9 10 25 21
Bud 6 1 7 12 11 12 28 19 20 – 28 26 11 12 6 0 – 0 0 0 1 2 4 1
Bud Neck 0 0 3 1 0 0 2 4 1 – 0 0 0 0 0 0 – 0 0 1 1 0 0 1
Bud Site 0 0 0 0 0 0 8 0 4 – 5 7 0 0 0 0 – 0 – – – – – –
Cell Periphery 0 0 1 0 2 1 2 0 1 – 0 2 0 1 0 1 – 1 0 0 0 0 0 0
Cytoplasm 35 19 38 35 65 50 64 67 53 – 37 58 28 35 69 9 – 10 6 9 8 3 4 2
Endoplasmic Reticulum 12 7 14 5 12 17 11 2 11 – 3 1 18 3 22 2 – 1 4 0 0 1 8 6
Endosome 27 0 9 35 55 43 63 62 13 – 12 52 36 106 59 4 – 4 74 24 55 45 83 73
Golgi 12 3 1 7 3 0 0 1 1 – 0 0 21 24 28 0 – 1 46 18 24 29 103 140
Mitochondria 107 39 8 64 52 198 281 193 277 – 321 269 141 100 129 0 – 4 45 27 94 55 87 70
Nucleus 0 0 1 2 0 2 4 6 4 – 3 2 0 2 0 0 – 0 0 1 0 0 1 0
Nuclear Periphery 1 1 0 0 0 0 0 1 0 – 0 0 1 0 0 0 – 0 0 0 0 0 0 0
Nucleolus 0 0 0 3 0 1 1 3 3 – 2 0 1 1 3 0 – 0 0 0 0 0 0 1
Peroxisomes 2 0 0 4 2 6 7 4 1 – 2 12 6 22 4 0 – 0 11 1 8 11 18 25
SpindlePole 1 0 10 18 36 22 59 75 19 – 13 37 1 8 6 2 – 0 8 1 7 3 5 4
Vac/Vac Membrane 8 1 4 6 9 16 22 31 20 – 18 29 9 24 23 3 – 3 4 5 6 6 7 8
Unique Cell Count 177 65 103 161 228 308 453 392 364 362 406 224 272 308 19 20 212 98 224 175 355 364
Labelled Cell Count 217 77 125 208 279 373 570 480 433 445 498 280 339 352 23 24 212 98 224 175 355 364


Late Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.5 5.2 5.9 5.6 6.1 5.0 5.0 5.3 4.5 – 4.1 4.7 6.1 6.4 6.5 8.1 – 7.1 5.3 5.6 6.1
Std Deviation (1e-4) 0.6 0.6 0.7 0.9 1.0 1.2 0.8 1.0 1.0 – 0.7 0.9 0.9 0.9 1.1 1.5 – 1.4 0.6 1.1 1.3
Intensity Change (Log2) – – – -0.09 0.04 -0.26 -0.26 -0.16 -0.42 – -0.53 -0.33 0.04 0.11 0.12 0.45 – 0.25 -0.17 -0.09 0.05

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -3.8 -3.1 -8.5 -8.0 -8.2 0 – 0 0 -6.7 -8.9 -8.9 0 – 0
Bud 0.2 -0.7 0 -0.2 -0.8 0 – 0 0 -0.7 -0.9 0 0 – 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 – 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 – 0
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 – 0
Cytoplasm -2.7 -1.5 -4.4 -5.4 -4.4 -5.1 – -6.5 -5.2 -5.1 -5.2 -2.9 0.9 – 1.1
Endoplasmic Reticulum -3.2 -2.6 -2.7 0 0 0 – 0 0 -1.6 0 -2.0 0 – 0
Endosome 2.8 3.3 1.4 1.4 1.8 0 – 0 0 1.8 5.7 2.5 0 – 0
Golgi 0 0 0 0 0 0 – 0 0 2.8 2.7 2.8 0 – 0
Mitochondria 5.7 3.3 9.9 9.9 7.6 0 – 0 0 9.3 5.5 6.4 0 – 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 – 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 – 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 – 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 3.0 0 0 – 0
SpindlePole 0.4 1.5 -0.8 0.9 2.3 0 – 0 0 0 0 0 0 – 0
Vacuole 0 0 0.5 0 1.4 0.7 – 0 1.2 0 1.6 1.3 0 – 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.7935 1.5546 0.9437 0.9854 0.6973 1.4198 2.0032 2.4473 2.2382 1.9971 2.2596 2.1701 2.5498 2.8894 2.3414 1.9868 2.1538 2.5319
Actin 0.0255 0.0125 0.0116 0.0085 0.0039 0.0199 0.0432 0.0088 0.0264 0.0329 0.0274 0.0079 0.023 0.0082 0.0261 0.0018 0.0479 0.0081
Bud 0.0007 0.0008 0.0004 0.0003 0.0003 0.0003 0.0007 0.0004 0.0004 0.0012 0.0009 0.0002 0.0006 0.0004 0.0004 0.0002 0.0002 0.0002
Bud Neck 0.0082 0.0007 0.0018 0.0008 0.0024 0.0009 0.0024 0.0005 0.0008 0.0008 0.0008 0.0011 0.0006 0.0006 0.0008 0.0004 0.0005 0.0028
Bud Periphery 0.0008 0.0004 0.0002 0.0003 0.0004 0.0005 0.0007 0.0002 0.0004 0.002 0.0006 0.0004 0.0008 0.0002 0.0002 0.0001 0.0002 0.0001
Bud Site 0.0111 0.0054 0.0014 0.0011 0.0059 0.0004 0.0129 0.0093 0.0025 0.001 0.0013 0.0003 0.0029 0.0139 0.0029 0.0005 0.0007 0.0003
Cell Periphery 0.0007 0.0001 0.0001 0.0001 0.0005 0.0001 0.0004 0.0001 0.0002 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0 0 0.0001
Cytoplasm 0.01 0.0412 0.031 0.008 0.0066 0.0142 0.0098 0.0205 0.0153 0.0084 0.0102 0.0074 0.0355 0.0358 0.0196 0.0132 0.0083 0.0285
Cytoplasmic Foci 0.1836 0.2368 0.2069 0.1611 0.2014 0.1385 0.2302 0.2707 0.2171 0.2088 0.2336 0.1855 0.2108 0.2441 0.208 0.2273 0.2282 0.1787
Eisosomes 0.0007 0.0001 0.0002 0 0.0003 0.0002 0.0003 0 0.0002 0 0.0001 0 0.0002 0.0001 0.0001 0 0.0002 0
Endoplasmic Reticulum 0.0028 0.0021 0.001 0.0018 0.0011 0.004 0.0032 0.0009 0.0013 0.0005 0.0005 0.0019 0.0051 0.0011 0.0026 0.0012 0.0009 0.0019
Endosome 0.3439 0.3797 0.338 0.5444 0.3114 0.352 0.3033 0.3326 0.2986 0.3667 0.2874 0.2855 0.341 0.3263 0.3549 0.5398 0.2901 0.3428
Golgi 0.2324 0.2365 0.2929 0.2308 0.3345 0.3612 0.2668 0.3072 0.3503 0.3158 0.3697 0.4258 0.2713 0.2999 0.3096 0.1679 0.3575 0.3873
Lipid Particles 0.0611 0.0132 0.0401 0.0092 0.0594 0.0151 0.0314 0.0044 0.008 0.0133 0.0139 0.011 0.0357 0.0042 0.0109 0.0057 0.0122 0.0058
Mitochondria 0.0213 0.0087 0.0119 0.0067 0.0093 0.0235 0.0169 0.0066 0.0206 0.0073 0.0102 0.0189 0.0068 0.0178 0.008 0.0021 0.004 0.0184
None 0.0244 0.018 0.0089 0.0007 0.0062 0.0008 0.0023 0.0046 0.0005 0.0005 0.0002 0.0002 0.0126 0.0146 0.0009 0.0002 0.0005 0.0012
Nuclear Periphery 0.006 0.0004 0.0007 0.0007 0.0021 0.0034 0.006 0.0002 0.0004 0.0002 0.0002 0.0015 0.0077 0.0004 0.0006 0.0005 0.0006 0.0007
Nucleolus 0.0028 0.0001 0.0001 0.0001 0.0116 0.0002 0.0004 0.0001 0.0001 0.0001 0 0 0.0005 0.0001 0.0001 0.0001 0 0
Nucleus 0.0049 0.0003 0.0002 0.0002 0.0049 0.0004 0.001 0.0002 0.0001 0.0001 0.0001 0.0002 0.0018 0.0003 0.0002 0.0001 0.0001 0.0002
Peroxisomes 0.0407 0.0362 0.0437 0.0195 0.0212 0.0571 0.0615 0.0296 0.0533 0.0333 0.0406 0.0485 0.0338 0.0275 0.049 0.032 0.0444 0.0174
Punctate Nuclear 0.0098 0.0011 0.0007 0.0007 0.0105 0.0014 0.0031 0.0004 0.0003 0.0006 0.0004 0.0003 0.0043 0.0005 0.0019 0.0004 0.0012 0.0004
Vacuole 0.0057 0.0039 0.0058 0.0029 0.0044 0.0029 0.0019 0.0019 0.0019 0.004 0.0008 0.0014 0.0025 0.0028 0.002 0.0047 0.0012 0.0031
Vacuole Periphery 0.0026 0.0017 0.0023 0.0021 0.0017 0.0031 0.0016 0.001 0.0014 0.0023 0.0011 0.0019 0.0023 0.001 0.0014 0.0019 0.0011 0.0018

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 17.233 14.0848 13.391 21.8743 20.4282 16.7314 22.8081 27.1834 23.6753 24.266
Translational Efficiency 0.5337 0.7247 0.7929 0.4868 0.4474 0.5771 0.4142 0.4556 0.5121 0.4847

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2137 1153 289 503 1951 364 1492 1316 4088 1517 1781 1819

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 710.85 768.36 1059.43 1022.44 768.47 853.41 982.92 950.69 738.35 788.77 995.34 970.53
Standard Deviation 76.89 113.84 149.40 140.49 100.60 113.95 119.51 134.06 93.54 119.52 127.99 139.61
Intensity Change Log 2 — 0.112237 0.575671 0.524399 — 0.151250 0.355085 0.306986 — 0.132635 0.465296 0.415552

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000521 0.002721 0.031785 0.008431 0.000904 0.003670 0.003623 0.017950 0.000704 0.002949 0.008192 0.015317
Bud Neck 0.009569 0.002459 0.006543 0.007762 0.002825 0.004767 0.004477 0.003198 0.006350 0.003013 0.004812 0.004460
Bud Site 0.004815 0.009158 0.048972 0.046273 0.004945 0.011216 0.013198 0.041870 0.004877 0.009652 0.019003 0.043088
Cell Periphery 0.000064 0.000065 0.000186 0.000091 0.000058 0.000195 0.000058 0.000062 0.000061 0.000096 0.000079 0.000070
Cytoplasm 0.077157 0.022916 0.020523 0.036514 0.016655 0.035804 0.030353 0.053986 0.048283 0.026008 0.028758 0.049155
Cytoplasmic Foci 0.503876 0.364748 0.228678 0.316247 0.300696 0.367504 0.316664 0.391150 0.406908 0.365409 0.302387 0.370438
Eisosomes 0.000153 0.000084 0.000085 0.000063 0.000096 0.000189 0.000053 0.000062 0.000126 0.000109 0.000058 0.000062
Endoplasmic Reticulum 0.000394 0.001017 0.008684 0.000951 0.000691 0.000757 0.001800 0.000785 0.000536 0.000955 0.002917 0.000831
Endosome 0.045126 0.149580 0.118876 0.202804 0.131611 0.158991 0.187005 0.123811 0.086401 0.151838 0.175950 0.145654
Golgi 0.181496 0.327364 0.077216 0.050070 0.432947 0.295893 0.062809 0.128213 0.301501 0.319813 0.065147 0.106604
Lipid Particles 0.025183 0.012535 0.019980 0.005869 0.011974 0.011617 0.025672 0.005625 0.018879 0.012315 0.024748 0.005692
Mitochondria 0.060768 0.040028 0.000766 0.005272 0.049186 0.036348 0.003854 0.002910 0.055241 0.039145 0.003353 0.003563
Mitotic Spindle 0.020203 0.023458 0.306599 0.131984 0.010618 0.010066 0.224347 0.100501 0.015629 0.020245 0.237694 0.109206
None 0.001364 0.000185 0.000079 0.000055 0.000630 0.000243 0.000614 0.000071 0.001014 0.000199 0.000528 0.000066
Nuclear Periphery 0.000139 0.000185 0.001045 0.000940 0.000099 0.000061 0.001363 0.000109 0.000120 0.000155 0.001311 0.000338
Nuclear Periphery Foci 0.000376 0.000598 0.019329 0.003734 0.000416 0.000398 0.010929 0.001158 0.000395 0.000550 0.012292 0.001870
Nucleolus 0.001603 0.000524 0.000266 0.000959 0.001131 0.000407 0.001449 0.000113 0.001378 0.000496 0.001257 0.000347
Nucleus 0.010262 0.000689 0.004434 0.001611 0.000957 0.002014 0.004174 0.001482 0.005822 0.001007 0.004216 0.001517
Peroxisomes 0.046092 0.024700 0.030459 0.063673 0.017618 0.032511 0.036205 0.080076 0.032503 0.026574 0.035273 0.075540
Vacuole 0.008121 0.010169 0.071530 0.109741 0.009873 0.020012 0.068399 0.044172 0.008957 0.012530 0.068907 0.062304
Vacuole Periphery 0.002715 0.006818 0.003965 0.006956 0.006070 0.007338 0.002953 0.002699 0.004316 0.006943 0.003117 0.003876

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.59 -4.75 -4.37 -2.67 3.47 -1.48 -6.39 -9.97 -5.49 -8.14 -2.85 -6.62 -10.93 -7.81 -4.10
Bud Neck 7.83 1.50 0.71 -6.44 -0.72 -1.81 -3.71 -1.68 1.08 3.00 5.34 1.53 2.31 -4.03 0.88
Bud Site -4.33 -9.37 -10.48 -9.17 0.88 -3.98 -7.88 -15.36 -11.07 -11.28 -5.52 -12.29 -18.78 -15.51 -10.05
Cell Periphery -0.05 -7.30 -1.35 -1.26 4.79 -1.89 -0.73 -1.19 1.79 -0.59 -1.90 -4.38 -1.69 1.32 2.08
Cytoplasm 13.83 11.14 4.31 -5.66 -4.61 -4.27 -7.09 -12.78 -5.57 -6.99 7.95 4.29 -4.72 -10.50 -7.75
Cytoplasmic Foci 20.17 24.33 21.34 7.49 -4.99 -6.44 -0.22 -10.08 -0.38 -8.61 7.37 19.80 9.85 2.61 -8.45
Eisosomes 6.61 5.81 4.20 1.16 1.25 -3.64 4.65 3.78 5.18 -1.62 1.75 10.00 7.46 4.93 -0.09
Endoplasmic Reticulum -1.48 -6.24 -2.85 0.07 5.79 -0.27 -6.09 -1.17 -0.98 5.87 -1.26 -9.60 -2.98 -0.04 7.95
Endosome -22.61 -9.23 -16.04 -3.08 -6.03 -3.01 -7.67 3.34 4.82 10.29 -15.16 -17.12 -11.61 3.69 6.19
Golgi -17.74 12.97 23.30 35.76 3.58 9.42 58.20 42.90 12.58 -11.34 -2.48 49.76 37.86 31.47 -8.35
Lipid Particles 6.14 1.69 12.69 3.44 5.80 0.18 -7.20 5.11 2.86 11.99 4.27 -3.62 13.57 4.48 13.13
Mitochondria 5.28 24.05 17.83 10.03 -2.03 2.38 18.75 19.33 6.76 1.72 5.20 29.30 28.45 13.73 -0.02
Mitotic Spindle -1.07 -14.50 -10.92 -10.47 7.43 0.22 -26.98 -16.25 -15.39 12.21 -2.08 -29.97 -19.01 -17.23 13.68
None 8.81 8.81 8.66 0.73 0.17 1.71 -0.36 2.65 1.57 1.95 6.69 1.12 7.64 2.33 1.94
Nuclear Periphery -0.51 -3.76 -1.97 -1.84 0.50 1.20 -6.69 -2.10 -5.83 6.41 -0.52 -7.35 -2.29 -1.77 5.10
Nuclear Periphery Foci -0.86 -6.09 -4.00 -3.69 4.84 0.36 -8.72 -5.74 -5.79 7.87 -0.76 -10.45 -6.36 -5.21 8.87
Nucleolus 4.03 5.03 1.75 -0.89 -1.24 1.93 -0.80 2.53 2.16 7.83 3.61 0.03 4.21 0.79 5.73
Nucleus 11.40 0.29 6.50 -4.07 1.97 -1.57 -6.49 -3.23 -1.13 3.16 9.67 -1.11 3.88 -4.14 3.79
Peroxisomes 8.22 3.79 -2.20 -6.23 -4.42 -4.20 -7.06 -14.39 -8.60 -9.12 2.97 -0.93 -11.61 -12.62 -9.89
Vacuole -2.13 -9.48 -15.65 -15.36 -6.04 -3.54 -19.02 -14.97 -8.95 4.12 -3.53 -21.56 -21.19 -19.54 -0.84
Vacuole Periphery -6.53 -1.41 -2.07 0.67 -1.24 -1.01 6.92 6.25 4.00 0.72 -4.52 4.49 1.67 4.87 -0.85
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Member of the ChAPs family (Chs5p-Arf1p-binding proteins); members include Bch1p, Bch2p, Bud7p, and Chs6p; ChAPs family proteins form the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; BUD7 has a paralog, BCH1, that arose from the whole genome duplication
Localization
Cell Percentages mitochondrion (20%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Bud7

Bud7


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Bud7-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available