Standard name
Human Ortholog
Description Tail-anchored ER membrane protein of unknown function; substrate of the phosphatase calcineurin; interacts with homolog Frt2p; promotes cell growth in stress conditions, possibly via a role in posttranslational translocation; FRT1 has a paralog, FRT2, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.05 – 0 0 0 0 – 0 0 0 0 – – – 0.06 0.05 0.05 0.13 0.14 0 0 0 0
Bud 0 0 – 0 0 0.06 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 – 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0.07 0.05 0 0.07 0
Bud Site 0 0 – 0 0 0 0 – 0 0 0 0 – – – 0 0 0 – – – – – –
Cell Periphery 0 0 – 0.06 0 0 0 – 0 0 0 0 – – – 0 0 0 0.05 0.08 0.09 0 0 0
Cytoplasm 0.77 0.79 – 0.94 0.87 0.81 0.82 – 0.42 0.55 0.45 0.55 – – – 0.27 0.25 0.26 0.24 0.22 0.28 0 0.33 0.22
Endoplasmic Reticulum 0 0.13 – 0 0.06 0 0.05 – 0 0 0 0.05 – – – 0.11 0.07 0.05 0.19 0.21 0.1 0 0 0
Endosome 0 0 – 0 0 0 0 – 0 0 0 0 – – – 0.32 0.29 0.4 0 0 0 0 0.05 0.18
Golgi 0 0 – 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Mitochondria 0.17 0 – 0 0 0.16 0.19 – 0.62 0.5 0.69 0.57 – – – 0.07 0.07 0.13 0.21 0.16 0.28 0.17 0.17 0.19
Nucleus 0 0 – 0 0 0 0 – 0 0.05 0 0 – – – 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 – 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 – 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 – 0 0 0 0 – 0 0 0 0 – – – 0.09 0.09 0.09 0 0 0 0 0.1 0.09
SpindlePole 0 0 – 0 0 0 0 – 0 0 0 0 – – – 0.26 0.34 0.2 0 0 0 0 0 0
Vac/Vac Membrane 0 0 – 0 0 0 0 – 0 0 0 0 – – – 0 0.05 0.08 0.05 0.06 0.08 0 0 0.13
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 3 11 – 0 2 1 0 – 0 0 0 0 – – – 9 7 6 23 41 1 0 0 0
Bud 6 2 – 0 1 4 0 – 1 0 2 2 – – – 5 3 1 1 1 1 0 0 0
Bud Neck 0 2 – 0 1 0 0 – 0 1 0 0 – – – 1 2 0 5 19 1 0 0 0
Bud Site 1 0 – 0 0 0 0 – 0 0 0 0 – – – 0 0 0 – – – – – –
Cell Periphery 2 9 – 1 3 2 3 – 0 0 2 0 – – – 1 1 3 9 21 3 0 0 0
Cytoplasm 111 178 – 17 69 57 70 – 11 24 30 33 – – – 39 37 33 41 62 11 0 2 3
Endoplasmic Reticulum 6 29 – 0 5 3 4 – 0 1 2 3 – – – 16 11 7 33 61 4 0 0 0
Endosome 4 7 – 0 0 0 1 – 0 1 1 0 – – – 47 43 51 5 10 0 0 0 2
Golgi 0 0 – 0 0 0 0 – 0 0 0 0 – – – 3 4 2 4 2 0 0 0 0
Mitochondria 25 2 – 0 3 11 16 – 16 22 46 34 – – – 11 10 17 36 46 10 0 1 2
Nucleus 0 1 – 0 0 0 1 – 1 2 1 2 – – – 0 0 1 0 0 0 0 0 0
Nuclear Periphery 0 0 – 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Nucleolus 1 0 – 0 0 0 0 – 0 0 0 1 – – – 0 0 1 0 0 0 0 0 0
Peroxisomes 0 0 – 0 0 0 0 – 0 0 0 0 – – – 13 14 11 0 1 0 0 0 1
SpindlePole 1 2 – 0 1 0 1 – 0 1 0 0 – – – 38 51 25 0 0 0 0 0 0
Vac/Vac Membrane 0 1 – 0 0 0 0 – 0 0 0 0 – – – 3 8 10 9 17 2 0 0 1
Unique Cell Count 144 226 18 79 70 85 26 44 67 60 147 149 128 175 291 39 2 8 14
Labelled Cell Count 160 244 18 85 78 96 29 52 84 75 186 191 168 175 291 39 2 8 14


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.1 5.4 – 6.8 6.3 5.0 5.1 – 4.6 4.6 4.3 4.5 – – – 7.1 7.0 6.7 – – –
Std Deviation (1e-4) 0.7 0.9 – 2.8 2.4 1.3 1.3 – 1.9 1.4 1.6 1.5 – – – 1.3 1.5 1.4 – – –
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.4602 -0.3276 -0.3068 -0.0541 -0.4974 -0.3432 -0.2372 0.0794 0.1033 0.0592 -0.5359 -0.2388 -0.1728 -0.409 -0.938 -0.8292 0.4363 -0.271
Actin 0.0169 0.0055 0.0235 0.0194 0.0089 0.0047 0.056 0.0024 0.0176 0.0332 0.0442 0.0038 0.085 0.0221 0.0186 0.0727 0.0507 0.0057
Bud 0.0035 0.0041 0.0012 0.0004 0.0007 0.0039 0.0014 0.0018 0.0006 0.0004 0.0012 0.0001 0.0038 0.0005 0.0011 0.0004 0.004 0.0002
Bud Neck 0.0023 0.002 0.0073 0.003 0.0019 0.0048 0.0019 0.0009 0.0087 0.0011 0.0025 0.0043 0.0008 0.0006 0.0022 0.0041 0.0014 0.0352
Bud Periphery 0.0042 0.002 0.003 0.0006 0.0016 0.003 0.0032 0.0041 0.002 0.0007 0.0029 0.0005 0.0025 0.0003 0.0014 0.0006 0.0071 0.0005
Bud Site 0.0073 0.0198 0.0086 0.0012 0.0034 0.001 0.0066 0.0165 0.0082 0.0013 0.0172 0.0013 0.0035 0.0114 0.0168 0.0009 0.0069 0.0005
Cell Periphery 0.0022 0.0012 0.0013 0.0002 0.0004 0.0006 0.0036 0.004 0.0031 0.0004 0.0012 0.0005 0.0006 0.002 0.001 0.0004 0.0003 0.0004
Cytoplasm 0.0887 0.1809 0.1504 0.07 0.1427 0.1933 0.0932 0.1273 0.1148 0.0602 0.1407 0.163 0.0828 0.195 0.1985 0.1923 0.0447 0.2216
Cytoplasmic Foci 0.1205 0.1008 0.0874 0.0651 0.0705 0.0811 0.1051 0.1048 0.0789 0.0761 0.1723 0.1448 0.1428 0.1077 0.1326 0.1519 0.0458 0.1076
Eisosomes 0.0012 0.0005 0.0009 0.0004 0.0004 0.0003 0.0018 0.0006 0.0007 0.0007 0.0013 0.0003 0.0011 0.0004 0.0006 0.0003 0.0005 0.0002
Endoplasmic Reticulum 0.0083 0.0087 0.0103 0.0033 0.0099 0.0065 0.0096 0.0068 0.0114 0.0046 0.0054 0.0057 0.0081 0.0271 0.0103 0.0101 0.0039 0.021
Endosome 0.0751 0.055 0.0553 0.0793 0.0515 0.0351 0.0472 0.0401 0.036 0.0494 0.0445 0.031 0.0966 0.0627 0.0945 0.0516 0.0293 0.0477
Golgi 0.0156 0.0094 0.0181 0.033 0.0183 0.0082 0.0107 0.0047 0.0084 0.0167 0.0159 0.0049 0.0366 0.0095 0.0232 0.0158 0.0606 0.0074
Lipid Particles 0.0411 0.0296 0.0257 0.038 0.0146 0.017 0.0747 0.0359 0.0338 0.0336 0.0352 0.0418 0.0759 0.0352 0.0782 0.0397 0.0294 0.0534
Mitochondria 0.0201 0.0026 0.0188 0.0508 0.0254 0.0115 0.0071 0.0118 0.0076 0.0267 0.0093 0.0029 0.0695 0.0011 0.0353 0.0086 0.0404 0.1235
None 0.53 0.5444 0.5413 0.6107 0.616 0.5958 0.5223 0.6151 0.6248 0.6555 0.3946 0.5768 0.295 0.5043 0.3559 0.3953 0.6479 0.3571
Nuclear Periphery 0.0069 0.0017 0.0044 0.0012 0.0052 0.0048 0.0077 0.0013 0.002 0.0102 0.0022 0.0012 0.0152 0.0016 0.002 0.0015 0.002 0.0013
Nucleolus 0.0026 0.0009 0.0023 0.0003 0.0003 0.0009 0.0026 0.001 0.0014 0.0009 0.0018 0.0003 0.0013 0.0004 0.0007 0.0002 0.0006 0.0003
Nucleus 0.0038 0.002 0.0035 0.0006 0.0011 0.0041 0.0027 0.0012 0.0017 0.0019 0.0016 0.0006 0.0017 0.0006 0.0017 0.0006 0.0007 0.0004
Peroxisomes 0.0266 0.0206 0.0172 0.0181 0.0088 0.0106 0.0259 0.0083 0.0246 0.017 0.0816 0.0099 0.0621 0.0104 0.0085 0.0476 0.0185 0.0058
Punctate Nuclear 0.0035 0.0032 0.0139 0.0016 0.0008 0.0077 0.0092 0.0021 0.0071 0.0061 0.0208 0.0035 0.009 0.0026 0.0032 0.0029 0.0028 0.0015
Vacuole 0.0146 0.0046 0.0043 0.002 0.0113 0.0037 0.0064 0.0088 0.0056 0.0024 0.003 0.0026 0.0039 0.0041 0.0122 0.0021 0.0017 0.0069
Vacuole Periphery 0.0047 0.0005 0.0012 0.0009 0.0063 0.0015 0.0011 0.0009 0.0009 0.001 0.0007 0.0004 0.0022 0.0005 0.0016 0.0003 0.0008 0.0017

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 9.7592 8.7242 9.7106 11.59 12.6533 9.1442 12.6802 13.5816 12.3338 14.4954
Translational Efficiency 0.6277 0.6826 0.5436 0.5132 0.457 0.6244 0.3597 0.4236 0.41 0.3436

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
169 1853 1148 1003 2046 2319 2333 1720 2215 4172 3481 2723

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 657.40 755.38 950.44 852.46 715.23 723.79 940.91 965.53 710.82 737.82 944.05 923.88
Standard Deviation 108.63 91.05 124.28 108.94 79.81 89.30 101.27 133.04 83.79 91.44 109.48 136.11
Intensity Change Log 2 — 0.200431 0.531824 0.374861 — 0.017164 0.395649 0.432914 — 0.107845 0.462474 0.405401

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.008336 0.010455 0.001240 0.005579 0.003110 0.002361 0.001849 0.003353 0.003509 0.005956 0.001648 0.004173
Bud Neck 0.061380 0.025900 0.004617 0.014920 0.019087 0.033767 0.011882 0.056576 0.022314 0.030273 0.009486 0.041232
Bud Site 0.018299 0.017798 0.016439 0.046001 0.004162 0.014295 0.005440 0.042711 0.005241 0.015851 0.009067 0.043923
Cell Periphery 0.001138 0.000439 0.000673 0.000572 0.000647 0.000385 0.000343 0.000231 0.000685 0.000409 0.000452 0.000357
Cytoplasm 0.111554* 0.233935* 0.489038* 0.310738* 0.359213* 0.263964* 0.491120* 0.428846* 0.340317* 0.250627* 0.490434* 0.385342*
Cytoplasmic Foci 0.253833* 0.381559* 0.046391 0.156834 0.295925* 0.348786* 0.066018 0.075454 0.292714* 0.363342* 0.059545 0.105430
Eisosomes 0.002498 0.002704 0.000122 0.000420 0.003617 0.001468 0.000317 0.000159 0.003532 0.002017 0.000253 0.000255
Endoplasmic Reticulum 0.005417 0.004998 0.015322 0.005855 0.005356 0.004112 0.006319 0.001274 0.005361 0.004505 0.009288 0.002962
Endosome 0.082638 0.040088 0.005280 0.037408 0.015331 0.052704 0.006286 0.027861 0.020467 0.047101 0.005954 0.031378
Golgi 0.053236 0.050772 0.000389 0.005726 0.027986 0.029881 0.000502 0.002182 0.029912 0.039160 0.000465 0.003487
Lipid Particles 0.148121* 0.054035 0.004580 0.030783 0.070685 0.065939 0.013878 0.015900 0.076593 0.060652 0.010812 0.021382
Mitochondria 0.033677 0.019490 0.000329 0.001833 0.007902 0.018043 0.000724 0.010126 0.009869 0.018685 0.000594 0.007071
Mitotic Spindle 0.003845 0.002494 0.001464 0.026738 0.000324 0.005114 0.002674 0.060183 0.000593 0.003950 0.002275 0.047864
None 0.001809 0.001235 0.001290 0.001494 0.002582 0.001976 0.001612 0.002920 0.002523 0.001647 0.001505 0.002395
Nuclear Periphery 0.000551 0.000239 0.001114 0.001531 0.000431 0.000549 0.002491 0.002517 0.000441 0.000411 0.002037 0.002154
Nuclear Periphery Foci 0.001121 0.000915 0.014798 0.007900 0.000628 0.000864 0.005401 0.001418 0.000665 0.000887 0.008500 0.003805
Nucleolus 0.001472 0.000741 0.000210 0.001468 0.000817 0.001230 0.000652 0.003002 0.000867 0.001013 0.000506 0.002437
Nucleus 0.034846 0.043602 0.262534* 0.102849 0.122293 0.055668 0.293710* 0.121656 0.115621 0.050309 0.283428* 0.114729
Peroxisomes 0.137346* 0.063979 0.000633 0.022215 0.028409 0.033223 0.006901 0.024529 0.036721 0.046883 0.004834 0.023676
Vacuole 0.035234 0.042377 0.133163 0.217812* 0.030680 0.063008 0.081799 0.118155 0.031027 0.053845 0.098738 0.154863
Vacuole Periphery 0.003649 0.002245 0.000374 0.001324 0.000813 0.002664 0.000082 0.000947 0.001029 0.002478 0.000178 0.001086

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.59 2.01 1.21 5.06 -2.70 1.50 2.69 1.10 -0.21 -1.38 -3.93 3.77 0.78 4.77 -2.83
Bud Neck 3.24 5.16 4.30 6.73 -8.49 -7.11 4.19 -12.74 -6.41 -16.21 -4.42 7.80 -7.54 -4.10 -17.12
Bud Site 0.09 0.33 -2.74 -4.52 -4.63 -8.31 -1.40 -11.81 -6.87 -10.99 -10.54 -4.06 -13.57 -8.05 -11.40
Cell Periphery 3.17 2.01 3.13 -0.22 5.10 4.33 8.01 12.91 3.74 4.75 5.94 6.00 10.85 3.67 6.39
Cytoplasm -8.72 -22.55 -11.32 -5.28 14.65 13.25 -13.73 -3.97 -14.95 7.54 14.28 -17.58 -1.89 -15.61 14.70
Cytoplasmic Foci -8.20 14.14 7.93 34.37 -15.25 -8.12 43.27 39.45 49.14 -1.96 -12.66 48.68 37.56 60.51 -10.75
Eisosomes -0.38 5.45 4.97 8.99 -6.43 8.32 14.18 14.93 11.31 4.51 6.00 15.08 15.25 13.44 1.08
Endoplasmic Reticulum 0.21 -5.01 -0.11 -0.99 11.51 1.85 -2.09 6.84 6.05 11.43 1.40 -6.88 4.18 3.91 15.43
Endosome 4.50 8.37 5.82 4.30 -9.41 -17.25 8.41 -4.83 10.84 -9.70 -15.01 12.16 -2.82 11.11 -13.31
Golgi 0.35 7.16 6.67 19.15 -2.90 -0.82 19.70 18.83 19.16 -6.01 -4.71 20.85 18.82 27.23 -4.40
Lipid Particles 5.88 9.08 7.81 9.07 -8.92 1.33 18.78 18.37 18.09 -0.34 4.76 22.08 19.07 19.92 -5.14
Mitochondria 2.32 5.59 5.40 12.23 -3.83 -7.27 9.26 0.04 7.42 -9.67 -7.01 10.81 4.50 12.82 -10.15
Mitotic Spindle 0.60 1.11 -5.39 -6.53 -6.85 -5.11 -4.91 -13.58 -11.98 -12.49 -5.43 -4.43 -15.21 -13.71 -14.14
None 0.61 0.76 0.34 -0.50 -1.07 1.12 2.26 0.12 -1.23 -2.81 1.90 2.75 0.90 -1.45 -2.86
Nuclear Periphery 2.40 -5.38 -7.80 -12.00 -5.06 -1.50 -13.40 -10.79 -10.28 -2.22 0.45 -14.88 -13.02 -13.12 -2.97
Nuclear Periphery Foci 0.75 -13.87 -9.62 -10.54 6.46 -2.12 -9.29 -3.42 -2.57 6.85 -2.77 -15.65 -9.99 -9.06 8.88
Nucleolus 1.48 2.57 -0.34 -1.92 -2.99 -3.11 -2.22 -8.54 -7.53 -6.67 -1.29 -0.61 -7.58 -7.30 -7.00
Nucleus -0.87 -22.28 -8.31 -13.60 18.78 18.40 -29.77 -3.17 -17.86 23.59 20.10 -34.56 -3.31 -22.69 30.26
Peroxisomes 4.85 9.20 8.11 14.71 -8.54 -2.29 12.64 3.61 5.90 -7.26 -4.20 16.14 7.92 14.63 -10.24
Vacuole -1.27 -16.26 -24.81 -28.26 -12.38 -12.82 -22.07 -26.94 -19.17 -9.99 -12.27 -30.45 -38.22 -32.91 -15.91
Vacuole Periphery 1.24 3.00 2.49 3.80 -2.15 -9.60 8.98 0.97 10.44 -9.31 -7.29 7.22 1.83 9.21 -6.11
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Tail-anchored ER membrane protein of unknown function; substrate of the phosphatase calcineurin; interacts with homolog Frt2p; promotes cell growth in stress conditions, possibly via a role in posttranslational translocation; FRT1 has a paralog, FRT2, that arose from the whole genome duplication
Localization
Cell Percentages ER (20%), cytoplasm (7%), mixed (56%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Frt1

Frt1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Frt1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available