Standard name
Human Ortholog
Description Geranylgeranyl diphosphate synthase (GGPS); increases the intracellular pool of geranylgeranyl diphosphate, suppressor of bet2 mutation that causes defective geranylgeranylation of small GTP-binding proteins that mediate vesicular traffic

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0 0.06 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.05 0.06 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Endosome 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.07 0.15 0.16 0.12 0.05 0 0.05 0.06 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0.2 0.17 0.26 0.29 0.2 0.19 0 0.06 0 0.08 0.1 0.08
Mitochondria 0.91 0.88 0.97 0.94 0.92 0.91 0.91 0.87 0.92 0.92 0.94 0.95 0.76 0.78 0.66 0.08 0.08 0.11 0.81 0.78 0.78 0.68 0.69 0.66
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0.06 0.11 0.11 0.09 0.12 0.11 0 0.14 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0.05 0.07 0.11 0.09 0.07 0.07 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.06 0 0.12 0.18 0.16 0.07 0 0.07 0.11 0.07 0.05
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.12 0.12 0.11 0 0 0 0 0 0
Vac/Vac Membrane 0.13 0.11 0 0 0.05 0 0 0 0 0 0 0 0.16 0.13 0.19 0.13 0.17 0.23 0 0 0 0 0.05 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 1 0 0 0 0 0 2 0 0 0 0 5 4 2 2 7 5 0 2 1 2 4 8
Bud 3 1 3 8 7 8 14 6 10 17 17 17 2 3 2 4 8 6 0 0 0 0 0 3
Bud Neck 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 2
Bud Site 0 0 1 1 0 4 1 6 6 5 2 5 0 0 0 0 2 3
Cell Periphery 5 12 2 7 2 2 1 6 0 6 2 6 5 7 14 11 6 7 0 0 0 0 0 1
Cytoplasm 0 7 3 8 10 17 11 25 15 12 10 9 3 7 18 4 8 7 0 5 0 0 0 2
Endoplasmic Reticulum 4 8 1 2 7 8 10 6 7 10 8 14 6 2 4 5 7 3 0 0 0 2 3 2
Endosome 13 4 0 0 9 1 4 5 2 7 1 1 6 19 25 17 25 13 13 8 7 12 13 11
Golgi 10 9 1 1 0 0 0 0 0 0 0 1 36 48 86 33 31 21 7 15 3 16 29 26
Mitochondria 231 217 123 253 410 376 509 530 418 456 341 574 134 223 221 9 12 12 217 202 108 142 205 218
Nucleus 2 1 0 0 2 7 4 11 5 4 2 3 1 1 0 3 3 3 0 0 0 1 0 0
Nuclear Periphery 5 3 4 11 26 44 63 54 53 52 16 83 2 5 7 1 3 4 3 1 3 0 4 0
Nucleolus 8 2 5 7 24 30 62 55 32 35 16 44 3 3 2 5 5 2 0 0 0 0 1 3
Peroxisomes 4 2 0 4 6 2 3 7 2 8 1 3 10 16 13 14 28 18 18 9 10 22 19 17
SpindlePole 3 2 0 2 2 4 1 7 5 13 2 2 5 6 3 14 18 12 1 0 0 0 0 1
Vac/Vac Membrane 33 28 5 5 21 8 20 25 13 13 12 6 29 38 64 15 26 26 3 10 0 7 13 24
Unique Cell Count 254 248 127 269 446 415 557 607 452 495 363 602 176 286 337 115 153 113 267 260 139 208 300 330
Labelled Cell Count 323 297 148 309 526 511 703 745 569 638 430 768 247 383 461 137 189 142 267 260 139 208 300 330


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.4 8.1 5.2 5.5 5.6 5.6 5.2 5.7 5.4 5.3 5.4 5.4 8.2 7.6 8.0 7.1 7.1 7.2 9.3 9.7 9.8
Std Deviation (1e-4) 1.0 1.5 1.1 1.5 1.5 1.7 1.7 1.7 2.0 1.7 1.8 1.7 1.5 1.5 1.6 1.3 1.3 1.5 2.3 2.3 2.2
Intensity Change (Log2) 0.07 0.1 0.12 -0.01 0.12 0.06 0.03 0.05 0.05 0.65 0.55 0.61 0.45 0.45 0.46 0.83 0.89 0.92

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 1.1 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 2.8 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 1.4 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 3.0 3.2 4.5 4.8 3.9
Golgi 0 0 0 0 0 0 0 0 0 5.2 4.6 6.1 6.2 5.1 4.8
Mitochondria -1.2 -1.9 -2.3 -2.1 -3.1 -1.8 -1.9 -1.3 -0.8 -5.0 -4.8 -6.9 -13.9 -14.8 -13.4
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 1.2 2.6 2.8 2.2 2.9 2.6 0.6 3.4 0 0 0 0 0 0
Nucleolus 0 0.7 1.3 2.5 1.9 1.3 1.3 0.2 1.4 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 4.1 5.1 4.7
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 4.1 4.0 3.8
Vacuole 0 0.4 0 0 0.1 0 0 0 0 3.4 2.9 4.1 2.6 3.5 4.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 9.5497 8.6794 8.9298 8.2817 7.7434 8.6713 8.7596 7.9767 8.7817 7.779 7.8296 8.6678 5.4961 6.7718 5.789 6.5152 4.6244 6.8445
Actin 0.0011 0.004 0.0008 0 0.0005 0.0004 0.0009 0.0027 0.0004 0.0013 0.0001 0.0003 0.0093 0.0007 0.0107 0.0017 0.0004 0.0001
Bud 0 0.0002 0 0 0 0 0.0001 0.0002 0 0.0003 0 0 0.0001 0 0.0006 0.0002 0.0001 0
Bud Neck 0 0.0001 0 0 0 0 0 0 0 0 0 0 0.0002 0 0.0004 0.0001 0.0001 0
Bud Periphery 0.0001 0.0003 0.0001 0.0001 0.0001 0.0001 0.0002 0.0002 0 0.0011 0.0003 0 0.0002 0.0001 0.0011 0.0002 0.0002 0
Bud Site 0 0.0003 0 0 0 0 0.0001 0.0004 0 0.0001 0 0 0.0003 0.0002 0.0049 0.0002 0.0003 0
Cell Periphery 0.0001 0.0001 0.0001 0.0001 0.0001 0 0.0001 0.0001 0 0 0 0 0.0001 0.0001 0.0002 0.0001 0.0001 0
Cytoplasm 0 0.0001 0 0 0 0 0 0 0 0 0 0 0.0002 0 0.0001 0.0001 0.0001 0
Cytoplasmic Foci 0.0012 0.0025 0.0027 0 0.0003 0.0008 0.0009 0.0024 0.0007 0.0002 0.0001 0.0004 0.0196 0.0012 0.0064 0.0078 0.0042 0
Eisosomes 0.0001 0.0002 0.0002 0.0002 0.0001 0.0001 0.0001 0.0001 0 0.0001 0 0.0001 0.0001 0.0001 0.0002 0.0001 0 0.0001
Endoplasmic Reticulum 0.0001 0.0001 0 0 0 0.0001 0.0001 0 0 0 0 0 0.0005 0.0001 0.0001 0 0.0001 0
Endosome 0.0041 0.0089 0.0016 0.0004 0.0022 0.0046 0.0036 0.0052 0.0028 0.0005 0.0006 0.0009 0.013 0.0032 0.0156 0.0053 0.0185 0.0003
Golgi 0.0106 0.038 0.0106 0.0007 0.0039 0.0194 0.0074 0.0157 0.0123 0.0014 0.001 0.0041 0.0271 0.0094 0.0224 0.0097 0.0091 0.0005
Lipid Particles 0.0043 0.0015 0.0004 0.0001 0.0005 0.0014 0.0113 0.0039 0.0093 0.0001 0.0007 0.0019 0.0437 0.0057 0.0135 0.0432 0.0272 0.0025
Mitochondria 0.9687 0.9357 0.9752 0.9975 0.9838 0.9695 0.9528 0.95 0.9699 0.9941 0.9949 0.984 0.8524 0.9569 0.8955 0.8392 0.9241 0.9722
None 0 0 0 0 0 0 0 0 0 0 0 0 0.0003 0 0.0001 0 0.0001 0
Nuclear Periphery 0.0001 0 0 0 0 0.0004 0.0005 0 0 0 0 0 0.0081 0 0.0001 0 0.0001 0.0004
Nucleolus 0 0 0 0 0 0 0.0001 0 0 0 0 0 0.0002 0.0001 0.0002 0.0001 0.0003 0
Nucleus 0 0 0 0 0 0 0.0002 0 0 0 0 0 0.0002 0 0.0001 0 0.0001 0
Peroxisomes 0.0071 0.0059 0.0032 0.0001 0.0007 0.0014 0.014 0.0166 0.0023 0.0006 0.0015 0.0035 0.0166 0.0145 0.0234 0.0869 0.01 0.0003
Punctate Nuclear 0 0 0 0 0 0 0 0 0 0 0 0 0.0015 0 0.0001 0.0003 0.0001 0
Vacuole 0.0004 0.0007 0.0016 0.0001 0.0014 0.0003 0.0025 0.0004 0.0007 0.0001 0.0002 0.0022 0.0012 0.0014 0.0014 0.0007 0.0025 0.001
Vacuole Periphery 0.0016 0.0015 0.0033 0.0006 0.0063 0.0015 0.0051 0.0019 0.0013 0.0002 0.0004 0.0024 0.0051 0.0062 0.0028 0.0042 0.0022 0.0225

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.6625 9.7855 7.9874 13.9649 7.0963 12.0345 10.1414 9.6829 8.7144 12.5123
Translational Efficiency 1.0494 0.8191 0.9339 0.6099 1.2087 0.5674 0.9697 0.6877 1.2495 0.9214

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
130 1497 233 101 1609 1581 821 1754 1739 3078 1054 1855

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 837.38 881.11 1319.86 1222.34 830.14 893.05 1166.00 1124.81 830.68 887.24 1200.01 1130.12
Standard Deviation 117.96 194.17 188.83 157.75 170.79 149.48 174.59 165.86 167.43 172.77 188.95 166.90
Intensity Change Log 2 0.073440 0.656431 0.545691 0.105386 0.490141 0.438255 0.089432 0.576041 0.493206

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001347 0.003963 0.017651 0.021628 0.001895 0.001505 0.004899 0.015355 0.001854 0.002701 0.007718 0.015697
Bud Neck 0.006566 0.003470 0.009356 0.002625 0.003177 0.000773 0.002221 0.001190 0.003430 0.002084 0.003798 0.001268
Bud Site 0.017527 0.007267 0.017550 0.014045 0.005429 0.002894 0.006564 0.007595 0.006334 0.005020 0.008992 0.007946
Cell Periphery 0.000790 0.000357 0.000494 0.000568 0.001107 0.000287 0.000223 0.001370 0.001083 0.000321 0.000283 0.001326
Cytoplasm 0.002492 0.001017 0.002797 0.001048 0.000749 0.000796 0.001599 0.001395 0.000880 0.000904 0.001863 0.001376
Cytoplasmic Foci 0.050765 0.028359 0.073609 0.050065 0.009409 0.014331 0.024149 0.010166 0.012501 0.021153 0.035083 0.012338
Eisosomes 0.000088 0.000087 0.000207 0.000197 0.000114 0.000051 0.000100 0.000142 0.000112 0.000068 0.000124 0.000145
Endoplasmic Reticulum 0.001884 0.000362 0.002035 0.001119 0.000429 0.000165 0.000364 0.000433 0.000538 0.000261 0.000733 0.000470
Endosome 0.088996 0.043147 0.053266 0.049307 0.014830 0.021220 0.017113 0.015120 0.020374 0.031884 0.025106 0.016982
Golgi 0.068914 0.040094 0.131100 0.173022 0.015716 0.023945 0.033613 0.031331 0.019693 0.031799 0.055164 0.039046
Lipid Particles 0.008237 0.006845 0.006468 0.002729 0.007518 0.002807 0.003158 0.000518 0.007572 0.004771 0.003890 0.000638
Mitochondria 0.601114 0.812026 0.546166 0.620465 0.904128 0.901850 0.857159 0.884450 0.881476 0.858164 0.788410 0.870077
Mitotic Spindle 0.009670 0.003898 0.041002 0.011171 0.001007 0.002010 0.007621 0.003377 0.001655 0.002928 0.015001 0.003802
None 0.000378 0.000342 0.000628 0.000336 0.000552 0.000190 0.000420 0.000264 0.000539 0.000264 0.000466 0.000268
Nuclear Periphery 0.001075 0.000155 0.001147 0.000299 0.000195 0.000078 0.000533 0.000062 0.000260 0.000116 0.000669 0.000075
Nuclear Periphery Foci 0.001829 0.000319 0.001277 0.000285 0.000376 0.000118 0.000781 0.000052 0.000485 0.000216 0.000890 0.000065
Nucleolus 0.005090 0.000331 0.000687 0.000038 0.000719 0.000434 0.000200 0.000026 0.001046 0.000384 0.000308 0.000027
Nucleus 0.003270 0.000350 0.000520 0.000065 0.000649 0.000325 0.000087 0.000024 0.000845 0.000337 0.000183 0.000026
Peroxisomes 0.074907 0.037712 0.055595 0.039511 0.024459 0.017242 0.023867 0.015939 0.028230 0.027198 0.030881 0.017223
Vacuole 0.018031 0.005232 0.020813 0.005756 0.003728 0.003973 0.008518 0.005349 0.004798 0.004585 0.011236 0.005371
Vacuole Periphery 0.037031 0.004666 0.017630 0.005722 0.003813 0.005005 0.006811 0.005840 0.006296 0.004840 0.009203 0.005834

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.20 -4.30 -2.69 -2.33 -0.48 0.80 -2.86 -6.42 -6.72 -4.62 -1.55 -4.89 -6.84 -6.45 -3.50
Bud Neck 1.65 -1.26 2.09 0.82 3.91 3.30 1.17 2.68 -1.73 2.77 1.76 -0.53 3.08 2.02 5.34
Bud Site 1.93 -0.05 0.35 -0.82 0.41 2.05 -0.72 -1.55 -4.19 -0.43 0.99 -1.58 -1.14 -2.37 0.71
Cell Periphery 2.60 1.73 0.92 -1.15 -0.40 3.42 3.66 -0.72 -3.80 -4.01 3.45 3.59 -0.71 -3.74 -3.87
Cytoplasm 2.56 -0.58 2.54 -0.10 1.31 -0.15 -1.47 -2.34 -1.52 0.61 -0.12 -1.87 -1.88 -1.62 1.17
Cytoplasmic Foci 3.25 -2.43 0.07 -2.41 2.14 -3.29 -5.86 -0.55 2.74 5.52 -5.84 -8.58 0.12 5.87 8.60
Eisosomes 0.09 -4.97 -3.70 -3.92 0.29 4.63 0.87 -1.54 -7.43 -2.87 3.41 -0.80 -1.93 -6.45 -1.50
Endoplasmic Reticulum 1.98 -0.15 0.96 -2.74 1.23 2.77 0.37 -0.04 -2.95 -0.41 2.36 -0.89 0.49 -2.07 1.24
Endosome 3.71 2.73 2.72 -0.73 0.42 -3.30 -1.15 -0.18 3.26 1.04 -5.47 -2.08 1.76 8.02 3.93
Golgi 2.75 -3.94 -3.87 -5.31 -1.53 -3.76 -5.22 -5.92 -2.64 0.59 -5.76 -8.65 -6.38 -2.43 3.48
Lipid Particles 0.56 0.65 1.96 2.63 2.00 3.30 2.98 5.18 4.41 4.35 2.05 2.68 5.48 6.99 5.57
Mitochondria -6.27 1.35 -0.42 4.97 -1.70 0.29 4.44 2.49 2.26 -2.61 3.04 8.16 1.34 -1.60 -7.23
Mitotic Spindle 1.16 -3.21 -0.05 -2.20 3.73 -1.49 -5.68 -4.86 -1.72 3.43 -1.77 -6.78 -3.10 -1.31 5.73
None 0.33 -3.15 0.60 0.11 5.06 6.02 2.13 4.79 -4.95 7.15 4.11 1.27 4.85 -0.06 9.37
Nuclear Periphery 1.56 -0.12 1.29 -0.93 2.95 1.25 -1.48 1.40 0.68 2.23 1.40 -2.07 1.89 0.95 3.41
Nuclear Periphery Foci 1.52 0.47 1.56 0.24 3.62 2.75 -0.92 3.57 2.58 1.67 2.11 -1.17 3.75 2.45 2.44
Nucleolus 1.53 1.40 1.62 3.15 1.46 0.57 1.41 1.94 1.30 2.69 1.49 1.74 2.52 2.13 2.56
Nucleus 1.71 1.56 1.89 2.46 1.66 0.78 1.38 1.53 1.89 3.15 1.24 1.60 2.02 3.15 2.45
Peroxisomes 2.54 1.16 1.91 -0.14 1.09 2.42 0.15 2.95 0.51 2.16 0.36 -0.65 3.69 4.02 3.73
Vacuole 3.15 -0.66 2.89 -0.33 4.00 -0.37 -3.29 -1.70 -1.46 2.02 0.30 -4.52 -0.62 -0.90 3.85
Vacuole Periphery 4.90 2.80 4.70 -0.95 5.01 -1.74 -3.00 -2.57 -1.05 0.89 1.89 -2.67 0.49 -1.46 3.24
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Geranylgeranyl diphosphate synthase (GGPS); increases the intracellular pool of geranylgeranyl diphosphate, suppressor of bet2 mutation that causes defective geranylgeranylation of small GTP-binding proteins that mediate vesicular traffic
Localization
Cell Percentages mitochondrion (97%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Bts1

Bts1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Bts1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available