Standard name
Human Ortholog
Description Deubiquitinating enzyme anchored to the outer mitochondrial membrane; probably not important for general mitochondrial functioning, but may perform a more specialized function at mitochondria
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0.06 0 0.05 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0 0
Cytoplasm 0.18 0.23 0.2 0.13 0.15 0.08 0.07 0.1 0.09 0.06 0.05 0 0.48 0.45 0.35 0.44 0.4 0.39 0 0 0 0 0 0.09
Endoplasmic Reticulum 0.05 0 0.05 0 0 0 0 0 0 0 0 0 0 0.06 0 0.06 0.07 0.05 0 0 0 0 0 0
Endosome 0 0.13 0 0 0.19 0 0 0 0 0 0 0 0 0.07 0.17 0.18 0.14 0.17 0.09 0.09 0.08 0.08 0.09 0.06
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.86 0.55 0.7 0.86 0.7 0.88 0.89 0.87 0.92 0.94 0.95 0.95 0.37 0.36 0.37 0.15 0.13 0.09 0.69 0.65 0.7 0.61 0.65 0.54
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.09 0.06 0.09 0 0 0 0 0 0 0 0.05 0 0.05 0.17 0.07 0.07 0 0 0.06 0 0 0
SpindlePole 0 0 0 0 0.05 0 0 0.06 0 0 0 0 0 0 0 0.1 0.1 0.17 0 0 0 0 0 0
Vac/Vac Membrane 0.05 0.2 0.06 0 0.09 0.08 0.06 0 0 0 0 0 0.11 0.16 0.12 0.12 0.18 0.21 0.08 0.09 0 0.08 0.06 0.11
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 6 1 3 9 4 1 6 3
Bud 1 3 3 7 3 12 7 13 8 4 10 19 0 1 2 2 1 1 0 2 0 0 3 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 3 4 1 1 2 5
Bud Site 0 1 0 0 1 1 2 4 2 1 7 2 0 0 0 1 0 1 – – – – – –
Cell Periphery 3 8 3 0 2 4 3 2 2 1 0 2 1 1 2 6 11 6 0 1 0 0 0 0
Cytoplasm 34 59 28 15 19 17 18 32 17 14 11 12 35 30 33 96 57 54 4 6 1 4 3 9
Endoplasmic Reticulum 10 10 7 0 3 1 0 0 4 0 1 1 3 4 3 13 10 7 1 7 1 1 1 1
Endosome 0 33 6 5 24 6 5 0 0 0 0 0 2 5 16 39 20 24 18 31 13 8 13 7
Golgi 0 2 0 1 0 0 0 0 0 0 0 0 0 0 3 2 1 4 2 4 4 2 0 2
Mitochondria 161 143 97 98 90 198 228 272 179 203 229 268 27 24 35 33 18 13 143 229 113 65 101 62
Nucleus 1 1 1 1 1 4 2 13 3 4 4 5 1 0 0 2 5 6 0 3 0 0 0 0
Nuclear Periphery 1 1 1 0 0 2 7 2 5 3 4 7 0 0 0 0 0 0 0 2 1 1 0 0
Nucleolus 0 0 0 0 0 0 3 5 1 1 1 3 0 0 0 0 0 1 1 2 0 0 0 0
Peroxisomes 0 3 12 7 11 8 4 2 0 1 1 1 4 3 5 36 10 9 3 5 10 2 1 0
SpindlePole 1 8 4 3 6 5 9 18 5 0 7 7 2 0 1 21 14 24 4 5 2 2 4 0
Vac/Vac Membrane 9 52 8 4 11 18 16 11 7 3 4 10 8 11 11 27 25 29 15 31 1 8 9 13
Unique Cell Count 188 262 139 114 128 226 255 312 194 216 240 283 73 67 94 216 142 138 210 355 162 106 156 116
Labelled Cell Count 221 324 171 141 171 276 304 374 233 235 279 337 83 79 111 278 179 180 210 355 162 106 156 116


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.7 4.9 4.6 4.2 4.7 3.7 3.3 3.8 3.5 3.3 3.3 3.1 5.2 5.3 5.2 5.2 6.5 6.4 4.3 4.9 5.4
Std Deviation (1e-4) 0.6 1.1 1.6 1.5 2.4 1.1 1.2 1.8 1.3 1.6 1.1 0.7 1.4 1.7 1.0 1.5 2.1 1.8 1.3 1.9 1.6
Intensity Change (Log2) – – – -0.14 0.03 -0.31 -0.46 -0.27 -0.38 -0.48 -0.48 -0.58 0.17 0.21 0.16 0.17 0.5 0.47 -0.1 0.08 0.24


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 2.1 3.1 3.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.2366 0.5736 0.3146 0.3264 0.0788 0.4305 1.9453 1.9523 2.3401 1.8412 1.8914 2.3438 3.0768 3.3093 3.2585 4.1291 3.9234 3.4648
Actin 0.0079 0.0048 0.0145 0.003 0.0116 0.0049 0.0147 0.008 0.028 0.0457 0.0492 0.0104 0.0172 0.0134 0.0075 0.0656 0.0806 0.0144
Bud 0.0008 0.0035 0.0051 0.0032 0.0015 0.0013 0.0024 0.002 0.0073 0.0144 0.002 0.0018 0.0008 0.0045 0.0029 0.0013 0.0073 0.0022
Bud Neck 0.0055 0.0014 0.005 0.0153 0.0049 0.0189 0.0044 0.0035 0.0068 0.0087 0.0018 0.0179 0.0056 0.0019 0.0067 0.0101 0.0012 0.008
Bud Periphery 0.0026 0.0085 0.0138 0.0097 0.0029 0.0051 0.0054 0.0039 0.0204 0.0594 0.0041 0.0057 0.0022 0.0114 0.0156 0.0089 0.0325 0.0065
Bud Site 0.0072 0.0371 0.0175 0.0041 0.0017 0.0029 0.0086 0.062 0.0504 0.017 0.0027 0.0038 0.0052 0.0578 0.0108 0.0015 0.0028 0.0039
Cell Periphery 0.0027 0.0033 0.0051 0.0022 0.0008 0.0018 0.0031 0.0061 0.007 0.0055 0.0124 0.0026 0.0027 0.007 0.0133 0.0028 0.0018 0.0027
Cytoplasm 0.0796 0.1316 0.0856 0.1748 0.061 0.1374 0.0967 0.2247 0.1291 0.0702 0.2047 0.148 0.0947 0.142 0.1584 0.1473 0.1097 0.1472
Cytoplasmic Foci 0.1385 0.0899 0.0832 0.1271 0.117 0.1234 0.1443 0.1291 0.1158 0.0428 0.1372 0.1579 0.1143 0.1034 0.0776 0.0368 0.0811 0.1475
Eisosomes 0.0013 0.0012 0.0028 0.0018 0.0004 0.0009 0.0008 0.0014 0.0018 0.0033 0.0004 0.0013 0.0015 0.0023 0.0027 0.0028 0.0011 0.0011
Endoplasmic Reticulum 0.0091 0.0061 0.0089 0.0058 0.0048 0.0091 0.0078 0.0049 0.0054 0.0044 0.0047 0.0078 0.014 0.0093 0.0069 0.0071 0.0068 0.0069
Endosome 0.1628 0.0951 0.0965 0.1634 0.2086 0.1133 0.1841 0.1234 0.1179 0.0648 0.1128 0.0995 0.1594 0.0892 0.086 0.0921 0.0737 0.1099
Golgi 0.0349 0.0225 0.0274 0.025 0.0379 0.0249 0.0588 0.0335 0.042 0.0391 0.0286 0.0394 0.034 0.0169 0.022 0.0143 0.0247 0.032
Lipid Particles 0.0479 0.0206 0.0157 0.013 0.023 0.0342 0.0363 0.0066 0.0074 0.0324 0.0111 0.0145 0.0426 0.0214 0.0165 0.004 0.0064 0.0264
Mitochondria 0.173 0.2035 0.2991 0.1865 0.1884 0.1947 0.1513 0.1199 0.1723 0.1545 0.0905 0.1278 0.1171 0.1063 0.1828 0.0972 0.2113 0.1577
None 0.2558 0.3223 0.2701 0.2207 0.2609 0.2528 0.2059 0.2215 0.2284 0.3844 0.2559 0.2984 0.3322 0.3612 0.3499 0.4662 0.3266 0.2746
Nuclear Periphery 0.0072 0.0023 0.0022 0.0013 0.0032 0.0043 0.0071 0.0008 0.0044 0.0019 0.0017 0.0013 0.0039 0.0029 0.0012 0.0052 0.0025 0.0014
Nucleolus 0.0026 0.0018 0.0031 0.0013 0.0011 0.0021 0.0012 0.002 0.0016 0.0019 0.0005 0.0011 0.0016 0.0019 0.0031 0.0009 0.0011 0.0021
Nucleus 0.0028 0.0024 0.0066 0.0023 0.0022 0.0038 0.0107 0.0029 0.0047 0.0031 0.0015 0.0022 0.0025 0.0024 0.0021 0.0019 0.0019 0.0028
Peroxisomes 0.0217 0.0188 0.0174 0.0092 0.0381 0.0341 0.0357 0.022 0.0289 0.0243 0.0622 0.0441 0.0152 0.026 0.0144 0.0097 0.0114 0.0361
Punctate Nuclear 0.0082 0.0015 0.0028 0.0012 0.002 0.004 0.0026 0.0028 0.0049 0.0026 0.0027 0.0029 0.005 0.0026 0.0012 0.0023 0.0017 0.0053
Vacuole 0.0215 0.0175 0.0137 0.0224 0.0199 0.0203 0.0145 0.0154 0.0123 0.0158 0.01 0.009 0.0225 0.0135 0.0151 0.0122 0.011 0.0083
Vacuole Periphery 0.0064 0.0042 0.0041 0.0066 0.008 0.006 0.0036 0.0034 0.003 0.0038 0.0032 0.0025 0.0058 0.0026 0.0033 0.0097 0.003 0.003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.7238 6.5758 5.8555 6.807 3.815 3.676 10.1395 10.5456 7.7301 11.4978
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2202 1152 275 1256 1299 1806 175 1602 3501 2958 450 2858

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 619.71 631.01 893.39 802.50 679.75 715.00 933.25 829.28 641.99 682.29 908.89 817.51
Standard Deviation 69.49 101.40 97.15 178.72 79.27 301.52 101.65 120.83 78.80 247.37 100.81 149.66
Intensity Change Log 2 — 0.026070 0.527697 0.372908 — 0.072939 0.457259 0.286855 — 0.050777 0.491280 0.328534

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000428 0.000619 0.003663 0.013468 0.000624 0.001279 0.005288 0.002671 0.000500 0.001022 0.004295 0.007416
Bud Neck 0.077405 0.035814 0.023660 0.044156 0.032924 0.029579 0.018867 0.040199 0.060901 0.032007 0.021796 0.041938
Bud Site 0.031505 0.036927 0.039951 0.132856* 0.021583 0.030238 0.028222 0.086234 0.027824 0.032843 0.035389 0.106723*
Cell Periphery 0.000456 0.000354 0.000216 0.000253 0.000521 0.000282 0.000285 0.000268 0.000480 0.000310 0.000243 0.000261
Cytoplasm 0.153003* 0.041454 0.048378 0.226407* 0.051943 0.041096 0.184111* 0.205488* 0.115506* 0.041235 0.101163* 0.214681*
Cytoplasmic Foci 0.262524* 0.147432 0.174201 0.139125 0.188730* 0.169017 0.162877 0.146389 0.235144* 0.160611 0.169797 0.143197
Eisosomes 0.000381 0.000147 0.000173 0.000208 0.000195 0.000174 0.000235 0.000121 0.000312 0.000164 0.000197 0.000160
Endoplasmic Reticulum 0.003653 0.000778 0.008731 0.002728 0.001721 0.000399 0.006537 0.003145 0.002936 0.000547 0.007878 0.002961
Endosome 0.053149 0.133763 0.129565 0.025125 0.080275 0.097224 0.082762 0.049266 0.063214 0.111454 0.111364 0.038656
Golgi 0.030846 0.095791 0.053570 0.022674 0.073643 0.113803* 0.008031 0.018922 0.046725 0.106789 0.035860 0.020571
Lipid Particles 0.026039 0.009739 0.010050 0.002375 0.016869 0.007003 0.012146 0.004245 0.022637 0.008069 0.010865 0.003423
Mitochondria 0.202921* 0.332300* 0.071567 0.047130 0.391689* 0.385117* 0.004917 0.044638 0.272961* 0.364547* 0.045647 0.045733
Mitotic Spindle 0.003553 0.013808 0.077607 0.061069 0.010048 0.017707 0.018768 0.074723 0.005962 0.016189 0.054725 0.068722
None 0.002095 0.004221 0.001151 0.002045 0.002573 0.001855 0.001488 0.001763 0.002272 0.002777 0.001282 0.001887
Nuclear Periphery 0.000596 0.000311 0.001820 0.000725 0.000502 0.000110 0.002260 0.001210 0.000561 0.000188 0.001991 0.000997
Nuclear Periphery Foci 0.000259 0.000446 0.003257 0.000528 0.000675 0.000150 0.004613 0.001045 0.000413 0.000265 0.003784 0.000818
Nucleolus 0.002269 0.004448 0.009646 0.000923 0.003346 0.001338 0.008088 0.002159 0.002668 0.002549 0.009040 0.001616
Nucleus 0.042173 0.015711 0.065454 0.048876 0.014878 0.007486 0.163302* 0.055444 0.032045 0.010689 0.103506 0.052557
Peroxisomes 0.022305 0.051450 0.075857 0.077839 0.043269 0.046068 0.047846 0.042388 0.030083 0.048164 0.064964 0.057968
Vacuole 0.069109 0.049616 0.163070 0.146883 0.041940 0.035904 0.232478* 0.209375* 0.059028 0.041244 0.190062 0.181912
Vacuole Periphery 0.015334 0.024868 0.038413 0.004606 0.022054 0.014171 0.006879 0.010309 0.017827 0.018337 0.026150 0.007803

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.28 -5.04 -7.84 -7.70 -4.91 -1.36 -2.53 -7.20 -2.13 1.41 -1.78 -4.87 -9.23 -7.64 -2.25
Bud Neck 10.37 13.43 10.00 -1.39 -4.73 1.12 4.30 -1.37 -2.90 -5.87 11.25 13.77 8.77 -3.19 -7.04
Bud Site -1.71 -1.79 -15.56 -13.36 -10.18 -3.90 -1.09 -13.98 -11.53 -8.90 -2.71 -2.04 -20.06 -17.77 -12.35
Cell Periphery 0.82 1.87 1.93 4.72 0.25 1.51 1.50 1.70 0.76 1.00 1.73 2.38 2.49 2.93 0.48
Cytoplasm 21.39 14.41 -10.08 -25.61 -20.49 2.78 -8.06 -23.95 -27.17 -1.80 21.25 1.55 -19.90 -37.43 -13.37
Cytoplasmic Foci 17.11 9.22 21.87 3.40 4.49 3.11 2.81 8.75 6.51 1.92 15.90 9.11 23.29 7.35 4.64
Eisosomes 6.83 5.60 5.07 -2.07 -0.36 1.02 -2.07 4.87 4.15 6.83 6.28 4.36 7.03 1.45 4.30
Endoplasmic Reticulum 7.08 -3.20 1.47 -7.79 3.68 5.87 -6.44 -3.80 -8.63 4.51 8.99 -4.99 -0.48 -11.63 4.89
Endosome -15.14 -8.18 14.60 21.74 11.85 -3.67 0.86 10.30 15.40 3.50 -14.90 -6.29 14.97 26.32 11.10
Golgi -14.63 -3.35 5.80 17.06 5.55 -8.24 18.13 16.65 25.82 -3.72 -19.03 3.27 16.22 30.71 4.59
Lipid Particles 9.46 7.62 16.54 7.45 5.63 5.69 2.28 8.13 3.50 5.25 11.85 7.67 17.84 7.38 7.31
Mitochondria -11.97 12.82 26.94 30.38* 3.30 0.48 41.60* 37.09* 43.97* -10.87 -11.81 30.03 43.61* 53.22* 1.23
Mitotic Spindle -5.83 -7.46 -12.42 -9.48 1.71 -3.90 -1.45 -13.76 -11.50 -6.68 -7.80 -7.33 -19.03 -14.81 -1.41
None -2.22 2.94 0.29 1.94 -0.78 0.86 1.93 1.52 0.27 -0.52 -0.88 3.33 1.16 1.54 -1.04
Nuclear Periphery 2.80 -4.06 -2.76 -5.03 2.52 5.19 -4.60 -6.35 -10.15 2.22 5.69 -6.06 -6.33 -11.13 3.09
Nuclear Periphery Foci -1.55 -3.93 -6.38 -1.80 3.43 3.19 -5.23 -2.41 -8.14 4.75 1.85 -6.22 -5.66 -7.76 5.37
Nucleolus -3.12 -3.57 2.41 4.22 3.95 3.71 -2.92 2.15 -2.27 3.84 0.21 -4.44 2.76 1.98 5.02
Nucleus 9.12 -2.98 -5.56 -11.99 0.71 3.91 -9.78 -15.34 -18.16 6.41 12.23 -8.79 -12.78 -21.77 4.88
Peroxisomes -8.24 -6.76 -11.39 -2.74 1.13 -0.80 -0.14 2.08 2.95 1.09 -8.02 -5.88 -8.07 -0.30 2.38
Vacuole 4.99 -8.25 -18.95 -21.25 -2.50 1.87 -12.00 -30.75 -32.48 -0.06 7.14 -13.92 -34.45 -38.64 -2.71
Vacuole Periphery -5.69 -4.57 13.22 13.33 7.13 5.26 8.35 8.80 5.65 -1.53 -0.50 -2.21 13.69 13.67 6.13
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Deubiquitinating enzyme anchored to the outer mitochondrial membrane; probably not important for general mitochondrial functioning, but may perform a more specialized function at mitochondria
Localization
Cell Percentages mitochondrion (61%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Ubp16

Ubp16


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ubp16-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available