Standard name
Human Ortholog
Description Protein involved in the synthesis of GlcNAc-PI; GlcNAc-PI is the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein; GlcNAc-PI stands for N-acetylglucosaminyl phosphatidylinositol
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.11 0 0.07 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0.07 0.11 0.3 0.09 0 0 0 0 0 0
Cytoplasm 0.37 0.49 0.53 0.53 0.68 0.54 0.6 0.54 0.48 0.58 0.59 0.48 0.72 0.62 0.76 0.78 0.65 0.64 0.08 0.1 0.11 0.19 0.19 0.16
Endoplasmic Reticulum 0.23 0.45 0.28 0.18 0.07 0.13 0 0 0 0 0 0.05 0.23 0.34 0.21 0.06 0.1 0 0.61 0.73 0.64 0.51 0.44 0.43
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.52 0 0.28 0.3 0.31 0.45 0.55 0.62 0.66 0.56 0.61 0.66 0 0 0 0 0.05 0.14 0.13 0.06 0.12 0.16 0.17 0.18
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.11 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.07 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.2 0.12 0 0.05 0 0.07 0.1 0.14
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 2 1 4 0 1 0 0 0 0 0 0 1 2 1 2 0 4 3 2 4 2 2 3
Bud 1 1 1 2 2 4 12 7 14 18 22 18 1 0 1 0 0 1 0 0 0 0 1 3
Bud Neck 0 0 0 0 0 1 1 0 1 1 0 0 0 1 0 0 0 0 1 2 2 2 1 1
Bud Site 0 0 0 0 0 0 0 2 3 3 3 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 1 1 5 3 3 4 3 8 5 4 10 3 20 18 2 6 5 1 0 5 1 2 1
Cytoplasm 52 74 105 103 153 170 305 208 248 307 271 272 56 131 205 14 13 37 13 18 28 26 31 27
Endoplasmic Reticulum 32 69 55 35 16 40 6 2 22 1 1 26 18 72 56 1 2 0 102 140 162 70 70 72
Endosome 0 4 0 2 0 0 2 0 0 2 0 1 0 0 0 0 0 0 4 1 2 0 2 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0
Mitochondria 73 2 56 59 69 140 281 239 342 300 280 375 0 0 1 0 1 8 21 12 30 21 27 31
Nucleus 5 0 0 0 1 2 5 1 4 2 5 4 0 0 1 0 0 3 1 0 0 0 0 0
Nuclear Periphery 2 0 0 0 1 1 3 1 10 2 1 3 0 0 0 0 0 1 4 0 1 0 0 0
Nucleolus 0 0 0 0 1 0 2 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 1 0 0 0 0 0 0 0 1 3 2 0 0 0 0 2 0 0 0 0 1 0 0 1
Vac/Vac Membrane 10 11 4 6 9 9 21 11 14 20 13 11 3 5 11 1 4 7 3 9 10 9 16 22
Unique Cell Count 140 152 199 194 225 312 510 385 519 532 462 569 78 210 268 18 20 58 166 192 255 138 160 168
Labelled Cell Count 178 164 223 216 255 371 642 474 667 665 604 720 82 231 294 22 26 66 166 192 255 138 160 168


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.7 6.0 4.0 4.3 3.9 3.6 3.3 3.4 3.0 3.1 3.2 3.2 6.1 6.1 6.2 6.6 6.9 6.8 6.5 6.7 6.8
Std Deviation (1e-4) 1.3 0.8 0.6 1.2 1.0 0.9 1.2 1.1 0.5 0.8 0.7 0.6 0.7 0.7 1.0 1.2 0.9 1.0 0.9 1.1 1.3
Intensity Change (Log2) – – – 0.11 -0.03 -0.12 -0.28 -0.22 -0.4 -0.34 -0.33 -0.31 0.63 0.63 0.65 0.73 0.8 0.78 0.72 0.76 0.77

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 4.1 3.4 0 0 0
Cytoplasm 0.1 3.2 0.4 1.7 0.3 -1.2 1.2 1.4 -1.2 2.9 2.0 5.4 2.0 1.0 1.5
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 -0.8 1.5 -1.7 0 -1.7 -4.5
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 -5.2 -8.3 -9.1 0 -2.2 -2.2
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 1.2 0.6 1.4 0.6 0 1.2 0.6 0 0 0 1.3 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.8532 0.5372 0.6055 0.5267 0.5753 0.4909 2.2477 2.5107 2.2622 2.1207 2.2845 2.6037 0.0952 0.0293 -0.0795 0.1298 -0.388 -0.2882
Actin 0.0106 0.0029 0.0036 0.0177 0.0199 0.0023 0.0138 0.0009 0.001 0.0385 0.0078 0.0037 0.0343 0.0015 0.0061 0.0034 0.0045 0.0012
Bud 0.0005 0.0006 0.0002 0.0005 0.0034 0.0001 0.0001 0.0002 0.0001 0.0002 0.0007 0.0004 0.0002 0.0001 0.0002 0.0004 0.0045 0
Bud Neck 0.002 0.0004 0.0039 0.0022 0.0018 0.0014 0.0006 0.0005 0.0038 0.0008 0.0024 0.0031 0.0065 0.0002 0.0015 0.0004 0.0051 0.0044
Bud Periphery 0.0014 0.0012 0.0003 0.002 0.0133 0.0003 0.0002 0.0003 0.0002 0.0003 0.0012 0.0017 0.0005 0.0001 0.0005 0.001 0.0118 0.0002
Bud Site 0.0044 0.0139 0.0029 0.002 0.0084 0.0002 0.0011 0.0202 0.0019 0.0002 0.0112 0.0002 0.0022 0.0011 0.0023 0.0009 0.0029 0.0001
Cell Periphery 0.0007 0.001 0.001 0.0007 0.0006 0.0003 0.0015 0.0014 0.0015 0.0004 0.0006 0.0005 0.0016 0.0008 0.0011 0.0006 0.0009 0.0006
Cytoplasm 0.2389 0.3094 0.3093 0.3302 0.3615 0.3623 0.2762 0.2748 0.3048 0.2206 0.278 0.3076 0.2573 0.3939 0.338 0.2601 0.4209 0.4075
Cytoplasmic Foci 0.0233 0.0183 0.0225 0.0173 0.0372 0.018 0.0116 0.01 0.0116 0.0119 0.0077 0.0112 0.0175 0.01 0.0111 0.0256 0.0152 0.0115
Eisosomes 0.0005 0.0003 0.0003 0.0007 0.0005 0.0001 0.0008 0.0004 0.0003 0.0003 0.0004 0.0001 0.0009 0.0001 0.0004 0.0002 0.0001 0.0001
Endoplasmic Reticulum 0.237 0.1781 0.1678 0.1134 0.1169 0.1536 0.2957 0.2408 0.2681 0.2265 0.2782 0.2389 0.3097 0.2585 0.2366 0.3823 0.2414 0.2449
Endosome 0.0454 0.0307 0.0324 0.0377 0.06 0.024 0.0169 0.0181 0.0223 0.0159 0.0134 0.0146 0.0208 0.0185 0.0153 0.0247 0.0186 0.0163
Golgi 0.0082 0.0024 0.0048 0.0037 0.0102 0.0025 0.0018 0.0006 0.0012 0.0051 0.0015 0.0009 0.0059 0.0027 0.002 0.0045 0.0008 0.0018
Lipid Particles 0.031 0.0055 0.0089 0.0219 0.0362 0.008 0.0085 0.0072 0.0114 0.0067 0.0047 0.0045 0.0192 0.0115 0.0059 0.0377 0.013 0.0132
Mitochondria 0.0078 0.005 0.0048 0.0063 0.018 0.0023 0.0009 0.0006 0.001 0.0014 0.0019 0.0013 0.0036 0.004 0.0075 0.0014 0.0016 0.0051
None 0.3083 0.3669 0.3856 0.3441 0.2276 0.3753 0.3313 0.3757 0.3401 0.4048 0.3569 0.3714 0.2805 0.2688 0.3453 0.2064 0.2114 0.2649
Nuclear Periphery 0.0299 0.0285 0.0202 0.034 0.0312 0.0242 0.0216 0.0242 0.0162 0.0515 0.0141 0.0198 0.0176 0.015 0.012 0.0204 0.0267 0.0124
Nucleolus 0.0026 0.0008 0.0011 0.0032 0.002 0.0005 0.0005 0.0013 0.0003 0.0002 0.0013 0.0004 0.001 0.0002 0.0003 0.0007 0.0005 0.0002
Nucleus 0.0116 0.0142 0.01 0.0167 0.0121 0.0126 0.0061 0.0081 0.0047 0.007 0.005 0.0079 0.0051 0.0053 0.0037 0.0051 0.0082 0.0054
Peroxisomes 0.0143 0.0037 0.0021 0.0053 0.0086 0.0007 0.0005 0.0003 0.0003 0.0006 0.0033 0.0005 0.0038 0.001 0.003 0.0143 0.0012 0.0038
Punctate Nuclear 0.0132 0.0076 0.009 0.031 0.018 0.0062 0.0034 0.0075 0.0019 0.0021 0.0042 0.0069 0.0062 0.0015 0.0028 0.0035 0.0056 0.0016
Vacuole 0.0063 0.0073 0.0077 0.0079 0.0088 0.0039 0.006 0.0061 0.0063 0.0036 0.0046 0.0036 0.0049 0.0049 0.0039 0.0054 0.0042 0.004
Vacuole Periphery 0.002 0.0014 0.0015 0.0016 0.0038 0.001 0.0008 0.0007 0.0008 0.0013 0.0007 0.0008 0.0008 0.0007 0.0007 0.0011 0.001 0.0006

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.2356 3.5102 6.946 9.7014 3.3941 5.2327 11.8307 5.1902 7.0857 10.0206
Translational Efficiency 0.8182 1.4186 0.8698 0.4688 1.6199 0.9507 0.5469 0.882 0.8075 0.7626

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1687 1699 178 1452 2408 1579 169 1515 4095 3278 347 2967

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 731.46 760.55 1005.14 922.52 775.51 739.63 987.69 964.63 757.36 750.47 996.64 944.02
Standard Deviation 83.02 109.60 113.83 119.49 94.27 112.81 114.24 126.98 92.39 111.65 114.36 125.16
Intensity Change Log 2 — 0.056264 0.458546 0.334801 — -0.068342 0.348913 0.314830 — -0.006515 0.403168 0.324558

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000202 0.000358 0.000679 0.001170 0.000200 0.000925 0.000627 0.001326 0.000201 0.000632 0.000654 0.001250
Bud Neck 0.005630 0.012097 0.003372 0.009777 0.004729 0.015580 0.003733 0.005524 0.005100 0.013775 0.003548 0.007605
Bud Site 0.003551 0.006055 0.003585 0.026936 0.002463 0.008466 0.003758 0.007278 0.002911 0.007216 0.003669 0.016898
Cell Periphery 0.000371 0.000331 0.000658 0.000859 0.000363 0.000609 0.000937 0.000541 0.000366 0.000465 0.000794 0.000697
Cytoplasm 0.318307 0.300425 0.204222 0.328224 0.404631 0.268287 0.206770 0.351278 0.369069 0.284944 0.205463 0.339996
Cytoplasmic Foci 0.134361 0.181354 0.045158 0.045212 0.128863 0.195483 0.051669 0.063473 0.131128 0.188160 0.048329 0.054536
Eisosomes 0.000553 0.000406 0.000167 0.000276 0.000465 0.000718 0.000291 0.000303 0.000501 0.000556 0.000227 0.000290
Endoplasmic Reticulum 0.204486 0.158099 0.169961 0.126831 0.143427 0.149725 0.214911 0.184302 0.168582 0.154065 0.191853 0.156177
Endosome 0.013863 0.022768 0.025491 0.012350 0.008803 0.028650 0.017495 0.009452 0.010888 0.025601 0.021596 0.010870
Golgi 0.012004 0.012574 0.000413 0.002072 0.008626 0.021226 0.000644 0.002004 0.010017 0.016742 0.000526 0.002037
Lipid Particles 0.120883 0.087754 0.029646 0.021685 0.066929 0.119288 0.035259 0.029526 0.089157 0.102944 0.032380 0.025689
Mitochondria 0.009517 0.010006 0.000453 0.001524 0.004331 0.018454 0.000419 0.000859 0.006468 0.014075 0.000437 0.001185
Mitotic Spindle 0.000483 0.000595 0.000304 0.007806 0.000450 0.002625 0.000707 0.005415 0.000464 0.001573 0.000500 0.006585
None 0.003842 0.005546 0.000664 0.001364 0.004399 0.003954 0.000412 0.004004 0.004170 0.004779 0.000541 0.002712
Nuclear Periphery 0.008676 0.008889 0.045610 0.013823 0.005859 0.005660 0.027308 0.015545 0.007020 0.007334 0.036696 0.014702
Nuclear Periphery Foci 0.005443 0.010071 0.158386 0.040505 0.004832 0.006542 0.119035 0.043592 0.005084 0.008371 0.139221 0.042081
Nucleolus 0.001359 0.002564 0.001192 0.000579 0.000672 0.001689 0.000821 0.000452 0.000955 0.002143 0.001011 0.000515
Nucleus 0.113752 0.098150 0.132491 0.152847 0.167527 0.071350 0.155507 0.155267 0.145374 0.085241 0.143700 0.154083
Peroxisomes 0.003884 0.005607 0.000799 0.001052 0.002215 0.010416 0.001219 0.002307 0.002903 0.007924 0.001003 0.001693
Vacuole 0.037113 0.072624 0.175979 0.203604 0.039353 0.065491 0.155112 0.117161 0.038430 0.069188 0.165816 0.159465
Vacuole Periphery 0.001719 0.003729 0.000771 0.001503 0.000860 0.004862 0.003365 0.000391 0.001214 0.004274 0.002035 0.000935

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.51 -5.88 -5.98 -4.81 -2.37 -3.87 -4.62 -2.82 -0.88 -1.57 -4.45 -7.29 -4.83 -2.62 -2.38
Bud Neck -4.49 1.98 -4.43 1.46 -6.18 -7.85 0.55 -1.52 6.77 -1.48 -8.75 1.62 -4.64 5.73 -5.17
Bud Site -2.41 -0.48 -7.34 -6.36 -7.03 -5.25 -1.70 -4.52 0.49 -2.45 -5.68 -1.68 -8.58 -5.36 -7.34
Cell Periphery 1.53 -4.40 -4.33 -4.83 -0.69 -5.68 -2.87 -3.24 1.71 2.10 -3.88 -4.19 -5.36 -3.22 1.56
Cytoplasm 2.33 7.09 0.52 -1.53 -6.61 18.82 12.03 6.84 -9.21 -8.25 15.82 14.13 6.26 -7.51 -10.54
Cytoplasmic Foci -8.52 14.99 22.91 29.84 0.44 -12.59 13.36 17.35 26.38 -1.99 -15.01 20.09 28.55 39.39 -1.24
Eisosomes 1.78 9.27 7.35 2.01 -3.10 -4.61 2.44 4.10 8.53 0.14 -1.07 6.71 7.73 6.13 -1.01
Endoplasmic Reticulum 5.39 2.75 12.85 7.66 3.83 -0.79 -2.98 -2.20 -1.33 1.99 2.64 -0.84 6.70 3.95 3.87
Endosome -8.23 -6.56 2.77 9.27 7.74 -16.22 -6.22 -0.46 15.27 5.82 -18.42 -9.40 1.63 17.38 9.63
Golgi -0.50 18.16 12.27 10.75 -1.92 -9.18 15.46 9.85 14.36 -2.34 -7.79 23.60 15.39 17.89 -3.00
Lipid Particles 7.40 20.83 27.82 23.29 3.41 -11.83 9.24 15.52 22.32 2.05 -4.47 20.87 30.70 31.54 3.73
Mitochondria -0.43 11.10 9.18 10.06 -1.98 -9.65 13.36 11.12 12.26 -2.72 -8.55 15.87 12.72 15.76 -2.80
Mitotic Spindle -0.46 0.73 -5.25 -5.20 -5.41 -2.47 -0.70 -4.63 -2.80 -4.33 -2.50 -0.30 -6.96 -5.53 -6.84
None -1.53 4.20 3.37 4.61 -2.66 0.39 6.64 0.56 0.13 -3.84 -0.86 7.69 2.48 2.88 -4.33
Nuclear Periphery -0.17 -6.61 -2.68 -2.37 5.87 0.26 -5.12 -7.11 -7.28 2.85 -0.44 -8.37 -7.17 -6.50 6.36
Nuclear Periphery Foci -4.90 -11.41 -14.67 -11.69 8.87 -2.69 -10.58 -16.61 -15.35 6.90 -5.74 -15.41 -22.21 -19.07 11.16
Nucleolus -2.69 0.13 2.98 4.98 1.85 -3.86 -0.93 3.92 4.52 1.94 -4.66 -0.52 3.68 6.63 2.48
Nucleus 3.65 -2.11 -7.29 -10.50 -0.92 23.35 0.57 1.55 -17.32 0.03 19.78 -0.48 -2.76 -19.41 -0.63
Peroxisomes -2.95 11.52 10.64 8.69 -0.65 -13.12 4.84 -0.11 9.90 -1.81 -11.85 12.20 4.17 12.76 -1.95
Vacuole -12.16 -11.12 -32.91 -26.49 -4.45 -8.34 -10.01 -21.25 -14.22 2.04 -14.32 -14.93 -37.74 -28.73 -1.79
Vacuole Periphery -8.39 2.93 1.24 4.93 -0.54 -10.50 -0.82 8.07 11.79 1.01 -13.93 -0.52 2.03 11.05 0.88
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein involved in the synthesis of GlcNAc-PI; GlcNAc-PI is the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein; GlcNAc-PI stands for N-acetylglucosaminyl phosphatidylinositol
Localization
Cell Percentages ER (79%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Gpi2

Gpi2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gpi2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available