Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L21B; homologous to mammalian ribosomal protein L21, no bacterial homolog; RPL21B has a paralog, RPL21A, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.06 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.95 0.96 0.91 0.96 0.91 0.87 0.87 0.75 0.74 0.78 0.79 0.99 0.96 0.99 0.98 0.99 0.98 0.93 0.91 0.85 0.88 0.88 0.86
Endoplasmic Reticulum 0 0 0 0 0 0.05 0.06 0.06 0.08 0.11 0.09 0 0 0 0 0 0 0.05 0 0 0.05 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0.05 0 0.15 0 0.06 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.06 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 1 0 1 4 3 4 7 5 4 0 1 0 2 0 0 0 0 0 0 0 3
Bud 1 5 0 0 0 0 2 1 0 1 3 1 0 0 0 0 0 0 0 8 10 1 5 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 9 12 6 5 5 2 5 7 11 5 4 1 6 10 0 0 0 0 0 0 0 0 0
Cytoplasm 82 338 192 144 211 188 119 178 119 133 125 127 140 292 280 135 125 164 85 325 165 135 196 165
Endoplasmic Reticulum 1 3 2 3 2 11 8 13 13 19 14 7 0 7 0 6 5 9 0 3 10 3 7 7
Endosome 0 1 0 0 0 2 0 0 2 1 1 0 1 0 1 0 0 0 0 0 1 0 0 1
Golgi 1 0 3 5 1 1 0 4 5 8 2 4 0 1 1 2 1 1 0 0 0 2 1 0
Mitochondria 0 1 1 0 2 3 7 2 24 7 10 13 0 1 0 3 0 0 0 1 0 0 1 1
Nucleus 0 0 0 0 0 0 2 0 0 0 1 1 0 0 0 0 0 1 0 1 0 1 0 0
Nuclear Periphery 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1
Vac/Vac Membrane 1 8 4 9 3 4 5 6 2 4 6 10 2 2 0 1 0 1 3 9 0 5 2 3
Unique Cell Count 84 354 199 159 219 206 137 204 158 180 160 161 142 303 282 138 126 168 92 358 196 154 222 192
Labelled Cell Count 86 365 215 168 224 216 149 213 177 191 172 171 144 310 292 149 131 176 92 358 196 154 222 192


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 69.1 42.7 60.6 54.4 39.8 36.0 18.4 29.3 25.2 26.2 25.2 23.8 75.8 70.3 63.0 98.7 117.3 142.6 70.4 66.3 68.7
Std Deviation (1e-4) 48.4 31.9 38.1 34.6 25.6 21.2 11.3 17.1 14.7 14.2 13.2 13.4 37.8 32.4 32.1 25.0 39.5 31.6 33.6 38.0 40.7
Intensity Change (Log2) – – – -0.16 -0.61 -0.75 -1.72 -1.05 -1.27 -1.21 -1.27 -1.35 0.32 0.21 0.06 0.7 0.95 1.23 0.22 0.13 0.18

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700050100150WT3HU80HU120HU160050100150WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3050100150WT1AF100AF140AF180050100150
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -1.0 -1.9 -1.8 -2.1 -1.8 -0.7 0 -1.3 -1.6 -2.5 -2.4 -1.3 0 0 -3.2
Cytoplasm -2.3 -0.1 -2.2 -3.3 -3.4 -5.9 -6.3 -5.4 -5.2 1.2 -0.1 2.2 0.7 1.5 0.6
Endoplasmic Reticulum 0 0 2.5 0 2.8 3.4 4.1 3.5 0 0 0 0 0 0 2.4
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 1.7 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 5.4 0 0 3.7 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 1.8 0 0 0 0 0 0 0 2.1 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 100.9839 138.5409 123.1647 118.0407 104.6229 108.9206 97.2585 134.0334 115.8307 96.6985 119.9807 83.6462 108.3023 137.5871 126.609 117.8848 101.0398 114.3815
Actin 0.0033 0.0015 0.0061 0.0008 0.0019 0.0015 0.009 0.004 0.0132 0.0057 0.002 0.0175 0.0057 0.0002 0.0005 0.0015 0.0093 0.0062
Bud 0.0028 0.0014 0.0018 0.0036 0.0018 0.0013 0.0022 0.0011 0.0026 0.0042 0.0031 0.0019 0.0011 0.0004 0.001 0.0008 0.0006 0.001
Bud Neck 0.0009 0.0009 0.0014 0.0013 0.0017 0.0013 0.001 0.0007 0.0011 0.0017 0.0013 0.0012 0.001 0.0005 0.0007 0.001 0.0025 0.0018
Bud Periphery 0.0058 0.0019 0.0024 0.003 0.0015 0.0028 0.0022 0.0006 0.002 0.0028 0.0046 0.0095 0.0014 0.0002 0.0009 0.0006 0.0005 0.0008
Bud Site 0.0043 0.0019 0.001 0.0012 0.0007 0.0002 0.0015 0.0016 0.0018 0.0013 0.0011 0.0006 0.001 0.0003 0.0004 0.0002 0.0004 0.0002
Cell Periphery 0.0406 0.0102 0.0236 0.0185 0.0242 0.0021 0.012 0.0072 0.0124 0.0105 0.0236 0.004 0.0322 0.0102 0.02 0.0049 0.0009 0.0211
Cytoplasm 0.5479 0.9079 0.7171 0.5066 0.606 0.6879 0.7191 0.9358 0.7924 0.671 0.808 0.6103 0.6953 0.9234 0.8531 0.7523 0.7596 0.7665
Cytoplasmic Foci 0.0136 0.0023 0.0026 0.0101 0.0085 0.0046 0.0048 0.0022 0.0068 0.0034 0.0027 0.0048 0.0068 0.0006 0.0013 0.0086 0.0273 0.008
Eisosomes 0.0004 0.0001 0.0002 0.0002 0 0 0.0004 0 0.0001 0.0002 0 0.0004 0.0002 0 0 0.0002 0.0001 0
Endoplasmic Reticulum 0.0572 0.0077 0.0282 0.0113 0.0275 0.1236 0.0581 0.0049 0.0113 0.0108 0.0242 0.0275 0.0473 0.0139 0.0108 0.0127 0.012 0.013
Endosome 0.0119 0.0037 0.0127 0.0135 0.0687 0.0199 0.0155 0.0034 0.0173 0.0188 0.0131 0.0717 0.0088 0.001 0.0026 0.0084 0.0111 0.0286
Golgi 0.0043 0.0012 0.005 0.0007 0.0217 0.0101 0.0039 0.0014 0.012 0.0127 0.0059 0.0239 0.0025 0.0001 0.0003 0.0014 0.0021 0.0076
Lipid Particles 0.0038 0.0005 0.0017 0.0045 0.002 0.0003 0.0026 0.0008 0.0014 0.0015 0.0003 0.0011 0.0041 0.0008 0.0007 0.0084 0.0078 0.0033
Mitochondria 0.0205 0.0076 0.0081 0.0104 0.0205 0.0096 0.012 0.0005 0.0106 0.0615 0.0026 0.1194 0.0057 0.0001 0.0036 0.0005 0.0221 0.0038
None 0.0062 0.0004 0.0014 0.0033 0.0007 0.0006 0.0038 0.0003 0.0013 0.0011 0.0005 0.0039 0.0049 0.0001 0.0069 0.0128 0.0112 0.0016
Nuclear Periphery 0.0389 0.0026 0.0156 0.0226 0.0181 0.0228 0.0383 0.0035 0.008 0.013 0.0054 0.0271 0.0331 0.0041 0.0081 0.0226 0.017 0.0095
Nucleolus 0.0052 0.0002 0.0017 0.0071 0.0013 0.0002 0.0009 0.0002 0.0006 0.0014 0.0004 0.0007 0.0042 0.0001 0.0006 0.001 0.0062 0.0213
Nucleus 0.0119 0.0019 0.0053 0.0133 0.0109 0.005 0.0146 0.0018 0.0042 0.0084 0.0036 0.0149 0.0126 0.0017 0.0041 0.0109 0.0137 0.0124
Peroxisomes 0.0007 0.0001 0.0002 0.0012 0.0005 0.0001 0.0004 0.0001 0.0002 0.0003 0.0001 0.0002 0.0006 0 0.0001 0.0172 0.0038 0.0014
Punctate Nuclear 0.0049 0 0.0001 0.0002 0.0002 0.0001 0.0014 0.0001 0.0004 0.0001 0.0002 0.001 0.0016 0 0.0003 0.0032 0.0443 0.002
Vacuole 0.1593 0.039 0.1298 0.2606 0.1295 0.0498 0.0782 0.0269 0.0833 0.138 0.0694 0.039 0.1121 0.0395 0.073 0.1085 0.036 0.0763
Vacuole Periphery 0.0556 0.0071 0.0341 0.1061 0.052 0.0561 0.0181 0.003 0.0171 0.0315 0.0279 0.0195 0.0177 0.0028 0.0111 0.0223 0.0115 0.0135

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1661.9601 1909.4446 2032.1389 1828.4874 1963.7595 1417.8775 1516.6344 1552.5111 1521.1333 1557.41
Translational Efficiency 1.3931 1.239 1.245 1.0699 1.4388 1.5338 1.3175 1.3764 1.3701 1.3598

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2343 1672 2592 1742 1734 2263 210 1592 4077 3935 2802 3334

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 5809.91 6828.49 9373.55 6923.36 5495.16 6436.12 8248.53 6298.93 5676.04 6602.84 9289.23 6625.19
Standard Deviation 1153.07 1507.16 1675.82 2227.59 1069.48 1302.48 1757.02 2154.78 1129.06 1406.56 1707.92 2215.19
Intensity Change Log 2 — 0.233051 0.690080 0.252957 — 0.228030 0.585976 0.196945 — 0.230612 0.640414 0.226002

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000024 0.000106 0.000078 0.000246 0.000027 0.000096 0.000164 0.000244 0.000025 0.000100 0.000084 0.000245
Bud Neck 0.000069 0.000379 0.000596 0.001549 0.000080 0.000408 0.007718 0.002072 0.000074 0.000395 0.001130 0.001799
Bud Site 0.001350 0.002137 0.002515 0.011390 0.001517 0.003638 0.005737 0.014258 0.001421 0.003001 0.002757 0.012759
Cell Periphery 0.017999 0.045987 0.023496 0.058663 0.019154 0.013113 0.037494 0.029510 0.018490 0.027081 0.024545 0.044743
Cytoplasm 0.719263 0.556709 0.552857 0.544943 0.629301 0.629105 0.168046 0.476675 0.681001 0.598344 0.524017 0.512345
Cytoplasmic Foci 0.012711 0.011006 0.006155 0.005430 0.020443 0.014730 0.013867 0.008095 0.016000 0.013148 0.006733 0.006702
Eisosomes 0.000001 0.000003 0.000002 0.000005 0.000001 0.000002 0.000009 0.000004 0.000001 0.000002 0.000002 0.000005
Endoplasmic Reticulum 0.003545 0.003656 0.002230 0.000865 0.005563 0.002143 0.000227 0.000737 0.004403 0.002786 0.002080 0.000804
Endosome 0.000703 0.001012 0.000690 0.000816 0.001009 0.001360 0.001172 0.002020 0.000833 0.001212 0.000726 0.001391
Golgi 0.039965 0.073922 0.040099 0.018649 0.067210 0.082597 0.042245 0.024333 0.051553 0.078911 0.040260 0.021363
Lipid Particles 0.018019 0.034799 0.015342 0.038579 0.018232 0.016039 0.030906 0.022748 0.018110 0.024010 0.016508 0.031020
Mitochondria 0.000286 0.000351 0.000338 0.000529 0.000302 0.000445 0.000096 0.000289 0.000293 0.000405 0.000319 0.000415
Mitotic Spindle 0.000472 0.001157 0.000796 0.001490 0.000650 0.001334 0.002441 0.005916 0.000548 0.001259 0.000919 0.003603
None 0.001138 0.002367 0.001289 0.001299 0.001267 0.001653 0.000500 0.001356 0.001193 0.001957 0.001230 0.001326
Nuclear Periphery 0.000441 0.000993 0.000980 0.000586 0.000558 0.000519 0.003664 0.000515 0.000491 0.000721 0.001182 0.000552
Nuclear Periphery Foci 0.009315 0.014563 0.010007 0.007565 0.010093 0.012349 0.019262 0.008086 0.009646 0.013290 0.010700 0.007814
Nucleolus 0.000051 0.000104 0.000095 0.000196 0.000055 0.000078 0.000184 0.000260 0.000053 0.000089 0.000101 0.000226
Nucleus 0.001305 0.003212 0.004263 0.008280 0.001344 0.002280 0.010327 0.011320 0.001321 0.002676 0.004718 0.009731
Peroxisomes 0.000080 0.000121 0.000050 0.000144 0.000092 0.000039 0.000020 0.000142 0.000085 0.000074 0.000048 0.000143
Vacuole 0.080911 0.139851 0.209635 0.253211 0.082908 0.104885 0.570217 0.336992 0.081760 0.119742 0.236660 0.293217
Vacuole Periphery 0.092351 0.107563 0.128486 0.045563 0.140193 0.113186 0.085703 0.054430 0.112699 0.110797 0.125280 0.049797

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.32 -5.73 -8.49 -5.02 -5.80 -3.42 -6.74 -7.18 -4.41 -2.06 -5.24 -6.69 -11.05 -6.59 -7.05
Bud Neck -6.53 -7.08 -11.73 -9.28 -6.38 -5.89 -8.56 -13.28 -11.23 6.07 -8.46 -10.33 -17.66 -14.45 -5.01
Bud Site -3.57 -5.58 -11.84 -11.01 -10.29 -6.06 -3.62 -11.68 -9.66 -4.21 -7.05 -6.81 -16.56 -14.16 -13.97
Cell Periphery -13.11 -4.18 -14.04 -2.40 -11.79 5.19 -3.78 -3.01 -6.85 2.15 -7.55 -4.98 -13.27 -7.18 -9.07
Cytoplasm 15.52 18.75 16.96 1.02 0.37 0.22 23.97 12.89 13.25 -15.69 11.38 19.48 21.66 10.33 0.78
Cytoplasmic Foci 1.47 7.05 4.46 3.10 -1.76 3.54 0.07 3.94 1.22 1.96 2.97 9.83 5.49 3.39 -3.78
Eisosomes -6.18 -7.59 -7.95 -4.45 -6.05 -2.99 -9.13 -10.21 -5.92 5.76 -6.47 -10.42 -11.34 -6.89 -6.27
Endoplasmic Reticulum -0.19 4.62 10.36 6.16 8.42 5.90 9.56 8.75 8.74 -4.74 4.61 7.61 12.96 9.39 8.96
Endosome -5.44 0.12 -1.53 1.74 -1.60 -4.43 -2.52 -2.48 -1.59 -1.39 -7.47 2.15 -2.83 -0.94 -3.21
Golgi -11.92 0.08 13.72 21.75 16.10 -4.57 8.24 17.93 23.02 5.39 -12.54 7.11 22.07 31.82 16.14
Lipid Particles -8.87 2.18 -8.79 -1.27 -10.55 1.52 -4.15 -2.54 -4.05 2.71 -5.32 1.53 -8.66 -4.35 -10.01
Mitochondria -1.54 -2.27 -1.99 -1.47 -1.41 -1.30 7.48 -0.44 1.08 -4.74 -1.71 -1.85 -2.04 -0.40 -1.28
Mitotic Spindle -2.28 -4.76 -3.56 -1.12 -2.38 -3.52 -2.07 -4.65 -4.16 -1.00 -4.18 -3.53 -5.38 -4.29 -4.42
None -2.37 -0.82 -0.79 1.86 -0.04 -1.18 7.98 -0.39 0.78 -3.58 -2.62 -0.31 -0.89 1.90 -0.35
Nuclear Periphery -11.31 -10.73 -3.73 6.78 6.83 0.59 -6.36 -0.38 -0.95 6.33 -7.91 -11.59 -3.22 4.05 9.74
Nuclear Periphery Foci -6.58 -1.71 1.93 8.26 4.02 -3.31 -5.15 2.16 5.22 5.94 -6.97 -2.88 2.80 9.44 5.66
Nucleolus -3.60 -15.45 -9.96 -4.09 -6.64 -2.74 -7.00 -5.50 -4.75 -1.66 -4.59 -16.56 -8.53 -6.26 -6.08
Nucleus -5.01 -8.58 -12.70 -9.29 -7.05 -4.18 -6.16 -12.92 -11.91 -1.42 -6.61 -10.11 -17.94 -15.33 -9.99
Peroxisomes -2.59 3.68 -2.95 -0.52 -4.90 4.50 5.64 -1.48 -3.98 -4.58 1.26 4.97 -3.05 -3.77 -5.83
Vacuole -11.94 -25.94 -26.57 -15.48 -5.34 -5.40 -25.85 -31.72 -28.51 11.66 -12.08 -31.51 -41.01 -31.77 -7.64
Vacuole Periphery -3.69 -8.77 15.64 18.10 24.89 5.51 9.42 21.25 18.41 4.39 0.68 -2.77 25.78 25.92 26.08
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L21B; homologous to mammalian ribosomal protein L21, no bacterial homolog; RPL21B has a paralog, RPL21A, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-2

Rpl21b

Rpl21b


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl21b-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available