Standard name
Human Ortholog
Description Karyopherin responsible for the nuclear import of Rpf1p; Rpf1p is a ribosome maturation factor
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0.05
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.1 0.11 0.13 0.08 0.13 0.09 0.09 – 0.09 0.1 0.07 0.18 0.27 0.32 0.28 0.36 0.23 0 0.05 0.05 0.1 0.07 0.06
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.09 0.1 0.15 – 0.35 0.35 0.35 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.69 0.49 0.47 0.4 0.39 0.48 0.5 0.49 – 0.47 0.57 0.52 0.42 0.4 0.25 0.58 0.5 0.38 0.86 0.75 0.68 0.57 0.53 0.44
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0.05 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.5 0.62 0.54 0.58 0.59 0.42 0.4 0.34 – 0.25 0.18 0.28 0.57 0.57 0.62 0.28 0.3 0.57 0.06 0.08 0.14 0.18 0.27 0.34
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
Bud 1 0 1 0 1 1 2 2 – 7 5 5 0 0 0 0 0 0 9 11 14 13 18 17
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1
Bud Site 0 0 0 0 0 0 2 3 – 6 6 4 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 1 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 10 25 54 48 37 53 48 60 – 57 43 31 38 74 106 12 23 9 9 14 26 20 24 20
Endoplasmic Reticulum 0 0 2 1 0 0 0 0 – 0 0 0 3 6 4 0 2 2 0 0 3 2 3 4
Endosome 1 0 2 5 15 3 3 7 – 0 2 4 0 0 0 1 1 0 3 3 6 4 8 11
Golgi 1 0 1 0 1 0 0 0 – 0 0 0 0 0 1 0 0 0 1 0 3 0 0 0
Mitochondria 0 9 5 6 11 37 49 104 – 211 154 165 0 0 0 0 0 1 1 7 2 0 2 4
Nucleus 317 116 229 151 176 203 257 338 – 286 248 245 91 109 82 25 32 15 426 206 355 124 195 161
Nuclear Periphery 0 0 1 1 3 6 2 6 – 12 4 13 0 0 0 0 0 0 3 0 15 2 6 5
Nucleolus 0 0 0 0 1 0 5 34 – 12 9 10 0 0 0 0 0 0 5 2 8 1 2 5
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 1 1 0 0 0 0 0 0 3 1 5 3 4 4
Vac/Vac Membrane 232 147 264 219 266 176 208 235 – 151 77 133 123 157 206 12 19 23 28 21 72 39 99 124
Unique Cell Count 461 239 486 376 453 421 515 691 604 438 471 215 274 332 43 64 40 494 274 525 218 372 369
Labelled Cell Count 562 297 559 432 511 479 576 789 742 549 611 255 346 399 50 77 50 494 274 525 218 372 369


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.1 8.1 8.1 8.1 7.5 6.8 6.8 6.6 – 5.8 5.9 6.1 9.6 8.4 9.7 7.2 7.8 10.5 9.9 10.4 11.0
Std Deviation (1e-4) 1.3 1.6 1.4 1.6 1.6 1.5 1.8 1.5 – 1.4 1.6 1.4 1.4 1.1 1.4 1.7 1.9 3.1 1.4 1.5 1.9
Intensity Change (Log2) – – – 0.0 -0.12 -0.26 -0.26 -0.29 – -0.49 -0.47 -0.42 0.24 0.05 0.25 -0.17 -0.06 0.37 0.28 0.35 0.44

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cytoplasm 0.7 -1.5 0.7 -0.9 -1.4 – -0.9 -0.6 -2.5 2.4 5.6 7.4 3.2 5.4 0
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Endosome 0 3.3 0 0 0 – 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria 0 1.7 5.5 5.9 8.2 – 14.0 13.7 13.8 0 0 0 0 0 0
Nucleus -2.0 -2.6 0.3 0.9 0.6 – 0.1 2.9 1.5 -1.2 -2.0 -6.5 1.4 0.4 -1.2
Nuclear Periphery 0 0 0 0 0 – 2.7 0 3.3 0 0 0 0 0 0
Nucleolus 0 0 0 0 5.0 – 3.1 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole 1.2 1.4 -3.8 -4.4 -6.9 – -9.9 -11.6 -8.2 0.7 0.8 2.2 -3.3 -3.7 0.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.6923 5.9137 5.3435 5.0129 4.1496 5.1886 5.6813 7.5416 6.6189 5.858 6.4514 6.4277 5.5052 7.6961 6.1024 5.8783 5.7368 6.0234
Actin 0.0248 0.0001 0.0037 0 0.0003 0.0002 0.0263 0.0034 0.0061 0.005 0.002 0.0087 0.0063 0.0006 0.0006 0.0001 0.0083 0.009
Bud 0.0002 0 0.0001 0 0.0001 0 0.0006 0.0003 0.0002 0.0004 0.0001 0.0002 0.0001 0.0001 0.0003 0 0.0003 0.0001
Bud Neck 0.001 0.0001 0.0003 0.0003 0.0005 0.0011 0.0016 0.0015 0.0009 0.0009 0.0002 0.0014 0.0003 0.0006 0.0004 0.0003 0.0019 0.0014
Bud Periphery 0.0003 0 0.0001 0 0.0001 0 0.0012 0.0004 0.0003 0.0011 0.0002 0.0004 0.0001 0.0001 0.0004 0 0.0008 0.0003
Bud Site 0.0006 0.0001 0.0009 0 0.0002 0 0.0018 0.0176 0.0011 0.0007 0.0008 0.0001 0.0006 0.0027 0.0006 0.0001 0.0006 0.0002
Cell Periphery 0.0001 0 0 0 0 0 0.0003 0.0006 0.0001 0.0001 0 0 0 0.0002 0.0001 0 0.0004 0.0001
Cytoplasm 0.0055 0.0182 0.0065 0.0033 0.0216 0.0078 0.0198 0.0038 0.0147 0.0144 0.0011 0.0051 0.0569 0.0187 0.0313 0.0102 0.0208 0.0063
Cytoplasmic Foci 0.0093 0.0037 0.0032 0 0.0006 0.0005 0.0197 0.0017 0.0135 0.0026 0.0068 0.001 0.0243 0.0008 0.0035 0 0.0066 0.002
Eisosomes 0.0002 0 0 0 0 0 0.0002 0.0002 0.0001 0.0001 0 0.0001 0.0001 0 0 0 0 0.0001
Endoplasmic Reticulum 0.002 0.0005 0.0009 0.0008 0.0034 0.0008 0.0094 0.0006 0.0034 0.0009 0.0001 0.0019 0.002 0.0006 0.0037 0.0003 0.0019 0.0011
Endosome 0.0117 0.005 0.0017 0.0003 0.0023 0.0017 0.0274 0.0033 0.0115 0.0085 0.0026 0.0023 0.0131 0.0008 0.011 0.0001 0.0173 0.0131
Golgi 0.0045 0.0004 0.0005 0 0.0001 0.0002 0.0065 0.0016 0.0049 0.005 0.0017 0.0013 0.0043 0.0007 0.0021 0 0.0049 0.0094
Lipid Particles 0.0176 0.0013 0.0014 0 0.0001 0.0007 0.0174 0.0087 0.0077 0.0061 0.0044 0.0024 0.0262 0.0021 0.0012 0 0.0034 0.0047
Mitochondria 0.0018 0.0002 0.0013 0.0001 0.0007 0.0002 0.0107 0.0053 0.0096 0.0497 0.0003 0.0008 0.0205 0.009 0.0021 0.0002 0.0064 0.0214
None 0.0019 0.0001 0.0005 0 0.0022 0.0003 0.0116 0.01 0.0034 0.0003 0.0005 0.0004 0.007 0.0001 0.0009 0.0001 0.0025 0.0002
Nuclear Periphery 0.0298 0.0186 0.0364 0.0296 0.0346 0.0171 0.0795 0.0187 0.0356 0.0271 0.0042 0.0196 0.032 0.0345 0.0412 0.0204 0.0192 0.0173
Nucleolus 0.0018 0.0008 0.0009 0.0007 0.0032 0.0018 0.0035 0.0019 0.0006 0.0009 0.003 0.0015 0.0011 0.0009 0.0012 0.0006 0.0021 0.0015
Nucleus 0.864 0.9495 0.9363 0.9639 0.924 0.9621 0.7214 0.9107 0.8767 0.8666 0.924 0.9479 0.7746 0.9207 0.8927 0.9663 0.883 0.9059
Peroxisomes 0.0066 0.0002 0.003 0 0 0.0001 0.0076 0.0061 0.003 0.0056 0.0035 0.0019 0.0185 0.0048 0.0004 0 0.0036 0.0008
Punctate Nuclear 0.015 0.0006 0.0012 0.0003 0.0039 0.0046 0.0271 0.0023 0.0056 0.0017 0.044 0.0014 0.0097 0.0009 0.003 0.001 0.0071 0.0021
Vacuole 0.0008 0.0004 0.0005 0.0003 0.0016 0.0005 0.0042 0.0012 0.0008 0.0013 0.0001 0.0013 0.0014 0.0008 0.0024 0.0002 0.0075 0.0016
Vacuole Periphery 0.0006 0.0002 0.0005 0.0002 0.0005 0.0002 0.0022 0.0003 0.0004 0.0009 0.0001 0.0004 0.0012 0.0003 0.0009 0.0001 0.0015 0.0012

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 29.3743 15.5961 16.5329 28.7413 20.312 17.7927 23.6539 27.2596 24.2068 32.0855
Translational Efficiency 0.6144 0.9808 1.0207 0.5613 0.7406 1.0972 0.737 0.5545 0.6418 0.6064

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
450 1344 872 128 216 1338 2198 1762 666 2682 3070 1890

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 977.94 978.48 1058.28 1158.32 866.69 989.94 1038.51 1119.34 941.86 984.20 1044.13 1121.98
Standard Deviation 150.29 161.98 210.72 169.03 112.79 134.15 150.77 172.94 148.66 148.86 170.19 172.95
Intensity Change Log 2 — 0.000796 0.113904 0.244216 — 0.191825 0.260927 0.369060 — 0.093707 0.184851 0.304221

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002576 0.000409 0.000676 0.000809 0.000617 0.000233 0.000257 0.000868 0.001941 0.000322 0.000376 0.000864
Bud Neck 0.007973 0.002649 0.006797 0.006391 0.002532 0.002876 0.013178 0.011576 0.006208 0.002762 0.011365 0.011225
Bud Site 0.014702 0.000509 0.001141 0.005475 0.000828 0.000553 0.002018 0.008865 0.010203 0.000531 0.001769 0.008636
Cell Periphery 0.000256 0.000076 0.000126 0.000171 0.000196 0.000057 0.000163 0.000132 0.000236 0.000067 0.000153 0.000135
Cytoplasm 0.107949 0.041968 0.031789 0.134904 0.037086 0.028448 0.037542 0.080777 0.084966 0.035223 0.035908 0.084442
Cytoplasmic Foci 0.020109 0.000976 0.000174 0.008726 0.002162 0.002296 0.000357 0.000631 0.014288 0.001635 0.000305 0.001179
Eisosomes 0.000059 0.000012 0.000011 0.000058 0.000027 0.000014 0.000011 0.000015 0.000049 0.000013 0.000011 0.000018
Endoplasmic Reticulum 0.008513 0.010403 0.004443 0.006380 0.016875 0.007786 0.002906 0.006527 0.011225 0.009097 0.003342 0.006517
Endosome 0.019533 0.000603 0.000281 0.014758 0.001113 0.001265 0.000721 0.001015 0.013559 0.000933 0.000596 0.001946
Golgi 0.017750 0.000383 0.000084 0.003900 0.000090 0.000817 0.000049 0.000435 0.012023 0.000600 0.000059 0.000670
Lipid Particles 0.005583 0.000912 0.000141 0.001925 0.001009 0.001051 0.000174 0.000265 0.004099 0.000981 0.000165 0.000377
Mitochondria 0.016971 0.001418 0.001154 0.001528 0.000780 0.001631 0.001316 0.002400 0.011720 0.001524 0.001270 0.002341
Mitotic Spindle 0.021746 0.002100 0.002893 0.118214 0.000034 0.003988 0.004820 0.011809 0.014704 0.003042 0.004272 0.019015
None 0.006324 0.004044 0.006055 0.007017 0.003696 0.001847 0.006189 0.007978 0.005472 0.002948 0.006151 0.007913
Nuclear Periphery 0.002900 0.004085 0.001092 0.005325 0.003042 0.004854 0.001570 0.002930 0.002946 0.004468 0.001434 0.003092
Nuclear Periphery Foci 0.002048 0.001570 0.000487 0.009098 0.003533 0.001849 0.000087 0.000968 0.002530 0.001710 0.000201 0.001519
Nucleolus 0.003389 0.002980 0.001161 0.001456 0.005737 0.002110 0.000673 0.001087 0.004150 0.002546 0.000812 0.001112
Nucleus 0.677099 0.920335 0.937874 0.556588 0.914448 0.932254 0.924538 0.845225 0.754077 0.926281 0.928326 0.825677
Peroxisomes 0.003537 0.000568 0.000082 0.000264 0.000322 0.000764 0.000076 0.000213 0.002495 0.000666 0.000078 0.000216
Vacuole 0.051894 0.003731 0.003359 0.107375 0.005532 0.004991 0.003196 0.015449 0.036858 0.004360 0.003243 0.021675
Vacuole Periphery 0.009089 0.000267 0.000183 0.009637 0.000339 0.000316 0.000159 0.000834 0.006251 0.000291 0.000166 0.001430

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.29 1.63 0.58 -4.90 -2.94 3.01 2.21 -1.31 -3.83 -3.23 2.70 2.33 1.00 -3.73 -2.87
Bud Neck 5.10 -0.52 -1.63 -4.39 -1.46 -1.50 -10.97 -13.00 -10.95 0.03 4.21 -6.38 -7.49 -12.83 -1.26
Bud Site 3.89 3.55 0.52 -6.88 -6.16 0.52 -3.25 -5.25 -5.33 -3.96 3.88 3.06 0.01 -5.94 -4.62
Cell Periphery 5.80 3.15 -0.48 -6.90 -3.94 3.98 1.52 2.19 -7.98 0.32 7.23 2.43 3.68 -8.20 0.07
Cytoplasm 5.92 7.73 0.01 -3.84 -5.02 1.24 0.50 -5.32 -11.60 -11.30 6.36 7.12 0.37 -10.98 -12.85
Cytoplasmic Foci 4.64 5.12 2.95 -3.66 -4.98 -0.33 2.84 2.28 3.48 -2.35 4.23 5.46 4.97 2.79 -4.33
Eisosomes 12.62 12.31 -2.70 -7.99 -7.88 3.25 3.61 1.50 -4.71 -7.33 12.37 12.48 7.95 -9.70 -10.35
Endoplasmic Reticulum -0.10 7.12 0.26 0.36 -4.94 3.77 5.62 4.18 1.46 -9.23 3.33 9.13 5.49 4.20 -9.80
Endosome 4.09 4.24 2.21 -2.98 -3.26 -0.48 1.64 0.52 0.96 -1.52 3.93 4.23 3.77 -1.26 -3.12
Golgi 2.79 2.90 2.65 -0.87 -1.84 -1.51 2.00 -1.30 1.19 -1.69 2.60 2.91 2.80 1.18 -1.99
Lipid Particles 1.51 2.03 0.66 -2.59 -6.68 -0.21 3.67 2.31 2.49 -5.62 1.46 2.30 1.87 1.54 -8.53
Mitochondria 2.98 3.10 3.06 0.02 -0.58 -2.50 -6.64 -9.76 -2.19 -5.27 2.78 2.88 2.27 -2.47 -5.80
Mitotic Spindle 3.49 3.32 -2.42 -3.45 -3.42 -3.24 -4.61 -7.61 -3.95 -4.00 2.77 2.41 -1.40 -6.06 -5.53
None 1.36 0.47 -0.29 -1.41 -0.69 2.21 -1.87 -3.73 -10.12 -2.37 2.70 -0.43 -2.50 -7.46 -2.76
Nuclear Periphery -1.38 3.81 -1.71 -0.67 -6.84 -2.55 1.74 -2.67 0.75 -12.34 -2.59 3.52 -2.78 0.27 -14.60
Nuclear Periphery Foci 0.47 3.69 -1.76 -2.08 -3.61 1.21 2.87 1.89 1.30 -6.37 1.14 4.81 2.13 1.28 -6.77
Nucleolus -0.21 1.42 1.38 2.81 -0.10 2.30 3.63 3.28 2.31 -2.90 0.95 3.03 2.69 3.68 -2.30
Nucleus -13.59 -14.89 3.48 11.41 12.13 -1.38 -0.96 7.93 14.33 15.51 -12.87 -13.43 -3.65 17.57 19.16
Peroxisomes 2.06 3.28 2.83 0.90 -2.73 -1.72 4.65 2.99 2.47 -1.69 1.54 3.56 3.32 2.74 -1.95
Vacuole 10.96 10.70 -4.28 -8.95 -8.86 -0.11 0.42 -11.21 -12.49 -13.11 10.44 10.38 3.68 -14.89 -14.70
Vacuole Periphery 3.05 3.13 1.66 -1.13 -1.21 0.24 2.07 -0.46 -0.61 -1.56 3.05 3.22 2.74 -1.08 -1.86
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Karyopherin responsible for the nuclear import of Rpf1p; Rpf1p is a ribosome maturation factor
Localization
Cell Percentages nucleus (24%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Kap120

Kap120


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Kap120-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available