Standard name
Human Ortholog
Description Histone H1, linker histone with roles in meiosis and sporulation; decreasing levels early in sporulation may promote meiosis, and increasing levels during sporulation facilitate compaction of spore chromatin; binds to promoters and within genes in mature spores; may be recruited by Ume6p to promoter regions, contributing to transcriptional repression outside of meiosis; suppresses DNA repair involving homologous recombination
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.05 0.08 0.05 0.07 0 0.05 0 0.05 0 0 0.1 0 0.05 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.06 0 0 0.09 0.06 0.08 0 0 0 0 0.07 0 0.08 0 0 0 0 0 0
Nucleus 0.89 0.92 0.96 0.93 0.9 0.71 0.73 0.71 0.71 0.66 0.63 0.65 0.85 0.77 0.75 0.88 0.84 0.84 0.87 0.92 0.86 0.7 0.58 0.38
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.48 0.38 0.17 0.24 0.12 0.23 0.4 0.35 0.56 0.48 0.75 0.55 0.19 0.19 0.2 0.17 0.19 0.23 0.09 0.06 0.12 0.14 0.25 0.33
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.14 0.19
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 1 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 1 1 0
Bud Neck 0 0 0 0 1 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 1 0 1 1 2 0 1 0 0 1 0 0 1 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 1 0 8 10 10 19 4 15 3 11 1 7 21 4 5 3 0 0 0 2 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 1 1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 1 0 0 0 7 2 5 20 18 14 9 0 0 0 7 4 6 0 0 0 0 0 5
Nucleus 89 87 80 83 145 88 155 189 161 193 104 136 23 127 161 93 81 61 96 87 85 49 80 58
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Nucleolus 48 36 14 21 20 29 85 93 127 142 123 115 5 32 42 18 18 17 9 5 12 10 34 49
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 2 3 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 1 0 0 0 0 0 2 6 0 0 0 0 0 0 1 0 2
Vac/Vac Membrane 0 0 0 0 0 0 0 4 0 2 0 3 0 3 2 1 1 1 2 1 0 2 19 29
Unique Cell Count 100 95 83 89 162 124 213 268 226 293 165 209 27 166 214 106 96 73 111 95 99 71 140 152
Labelled Cell Count 137 124 96 104 174 135 252 312 313 373 246 276 29 175 237 124 110 89 111 95 99 71 140 152


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 16.8 18.3 19.6 16.9 23.7 22.3 21.3 24.4 21.2 21.6 19.5 20.0 19.0 19.6 17.4 29.8 36.0 38.4 17.3 20.6 20.1
Std Deviation (1e-4) 6.5 6.2 7.0 5.5 11.2 10.1 9.0 10.2 8.5 10.4 8.4 9.5 7.3 8.4 8.6 17.0 15.9 18.2 7.6 7.4 9.3
Intensity Change (Log2) – – – -0.21 0.27 0.18 0.12 0.31 0.11 0.14 -0.01 0.03 -0.05 -0.0 -0.17 0.6 0.88 0.97 -0.18 0.07 0.04


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 2.5 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 2.8 0 0 0 0 0 0 0 0 0
Nucleus -0.9 -1.9 -4.6 -4.5 -4.9 -4.7 -5.5 -5.7 -5.5 -2.1 -3.9 -4.2 -2.1 -2.7 -2.7
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 1.1 -1.0 1.1 3.8 3.1 6.2 5.2 8.6 5.9 0 0.5 0.5 0 0.3 1.0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 15.7738 13.6312 15.8663 12.8772 11.2569 12.4097 16.8085 14.1925 17.8561 17.4025 16.6541 14.2925 15.7092 13.1516 15.9728 13.7566 13.498 13.1046
Actin 0.0001 0 0.0054 0 0.0002 0.0003 0.0227 0 0.0007 0.0013 0 0 0.0249 0 0 0.0051 0.0325 0
Bud 0 0 0 0 0.0004 0 0.0005 0.0003 0.0001 0.0002 0 0 0.0001 0 0 0.0011 0.0007 0.0001
Bud Neck 0 0 0.0003 0.0001 0.0003 0.0003 0.0016 0 0.0032 0.0006 0 0.0004 0.0002 0 0 0.0001 0.0002 0.0003
Bud Periphery 0 0 0 0.0001 0.0006 0.0001 0.0011 0.0006 0.0001 0.0003 0.0001 0.0001 0.0001 0 0 0.0018 0.0005 0.0001
Bud Site 0.0001 0 0.0001 0 0.0008 0.0001 0.0083 0.0001 0.002 0.0057 0 0 0.0004 0 0 0.0025 0.0016 0
Cell Periphery 0.0001 0.0001 0.0001 0 0.0015 0.0001 0.0009 0.0005 0.0002 0.0005 0.0001 0.0001 0.0001 0 0 0.0002 0.0003 0.0001
Cytoplasm 0.0002 0 0.0002 0 0.0006 0 0.0065 0 0.0028 0.0019 0 0 0.0044 0 0 0.0004 0.0081 0
Cytoplasmic Foci 0.0004 0 0 0 0.0275 0.0002 0.0054 0.0001 0.0029 0.01 0 0 0.0065 0 0 0.0008 0.0379 0
Eisosomes 0 0 0.0001 0 0.0001 0 0.0004 0 0 0.0001 0 0 0.0001 0 0 0.0001 0.0001 0
Endoplasmic Reticulum 0.0003 0 0.0031 0 0.0001 0 0.0024 0 0.0002 0.0007 0 0 0.0003 0 0 0.0003 0.001 0
Endosome 0.0045 0 0.001 0 0.0005 0.0002 0.0048 0 0.0031 0.0177 0 0 0.0042 0 0 0.0026 0.0056 0
Golgi 0.0001 0 0.0006 0 0.0002 0.0004 0.0015 0 0.0011 0.0049 0 0 0.0033 0 0 0.0019 0.007 0
Lipid Particles 0.0005 0 0.0001 0.0001 0.0086 0.0055 0.002 0.0001 0.0013 0.0184 0 0 0.0044 0 0 0.0002 0.0163 0
Mitochondria 0.0014 0.0002 0.0004 0.0001 0.0077 0.0006 0.0033 0.0099 0.0005 0.0023 0.0007 0.0002 0.0008 0.0004 0.0002 0.0446 0.0639 0.0003
None 0.0003 0 0.0001 0 0.0016 0 0.0027 0.0001 0.0007 0.0003 0 0 0.0009 0 0 0.0001 0.0034 0
Nuclear Periphery 0.0056 0.0014 0.0012 0.0003 0.0011 0.0001 0.0151 0.0003 0.0016 0.0005 0.0001 0.0001 0.0008 0.0003 0.0001 0.0004 0.0027 0
Nucleolus 0.0888 0.0714 0.0253 0.1239 0.4479 0.1869 0.0467 0.057 0.0158 0.0419 0.216 0.12 0.0448 0.0348 0.0115 0.0389 0.2207 0.1245
Nucleus 0.8952 0.9262 0.962 0.8733 0.4852 0.8032 0.8559 0.9245 0.9606 0.8864 0.7826 0.8782 0.8985 0.9605 0.9882 0.8974 0.5827 0.8744
Peroxisomes 0 0 0 0 0.0006 0.0016 0.0018 0.0002 0.0012 0.0022 0 0 0.0015 0 0 0.0003 0.0051 0
Punctate Nuclear 0.0003 0.0001 0.0001 0.0019 0.0054 0.0001 0.0112 0.0001 0.0008 0.0006 0.0001 0.0003 0.0033 0.0037 0 0.0001 0.0063 0
Vacuole 0.0008 0.0003 0.0001 0.0001 0.0036 0.0002 0.0033 0.003 0.001 0.0031 0.0001 0.0003 0.0003 0.0001 0 0.0007 0.0012 0.0001
Vacuole Periphery 0.0012 0.0002 0.0001 0 0.0056 0.0001 0.002 0.0031 0.0001 0.0003 0.0002 0.0001 0.0001 0.0001 0 0.0005 0.0022 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 112.1866 99.0185 42.39 34.3195 181.3582 105.028 117.1246 82.2999 63.3093 118.3065
Translational Efficiency 3.2401 3.5682 2.3473 2.9224 2.0461 3.4778 2.391 2.9576 2.1237 2.3656

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
464 320 333 2162 1195 1902 97 1653 1659 2222 430 3815

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1598.55 1622.42 2130.91 2791.59 1243.19 1557.12 2358.94 2662.98 1342.58 1566.52 2182.35 2735.86
Standard Deviation 522.58 472.63 582.20 797.69 443.35 392.06 570.80 803.50 493.36 405.30 587.43 802.75
Intensity Change Log 2 — 0.021383 0.414706 0.804323 — 0.324833 0.924092 1.098995 — 0.162043 0.659893 0.940691

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000564 0.000511 0.000727 0.000787 0.000613 0.000556 0.001301 0.000672 0.000599 0.000549 0.000857 0.000737
Bud Neck 0.001790 0.002358 0.005858 0.005216 0.001675 0.003032 0.007241 0.003478 0.001707 0.002935 0.006170 0.004463
Bud Site 0.000315 0.000232 0.000714 0.001083 0.001018 0.001056 0.001224 0.000629 0.000822 0.000938 0.000829 0.000886
Cell Periphery 0.000026 0.000036 0.000042 0.000241 0.000371 0.000262 0.000032 0.000141 0.000275 0.000229 0.000040 0.000198
Cytoplasm 0.000071 0.000044 0.000029 0.000232 0.001213 0.000437 0.000044 0.000180 0.000893 0.000380 0.000032 0.000210
Cytoplasmic Foci 0.001030 0.000145 0.000286 0.001736 0.001062 0.000823 0.001158 0.001076 0.001053 0.000726 0.000482 0.001450
Eisosomes 0.000147 0.000109 0.000209 0.000123 0.000263 0.000230 0.000317 0.000158 0.000231 0.000213 0.000233 0.000138
Endoplasmic Reticulum 0.000196 0.000289 0.000230 0.000244 0.000549 0.000687 0.000666 0.000157 0.000450 0.000630 0.000328 0.000206
Endosome 0.000018 0.000012 0.000006 0.000270 0.000089 0.000221 0.000012 0.000029 0.000069 0.000191 0.000007 0.000165
Golgi 0.000066 0.000024 0.000047 0.000079 0.000080 0.000231 0.000093 0.000045 0.000076 0.000201 0.000057 0.000064
Lipid Particles 0.000031 0.000003 0.000005 0.000026 0.000014 0.000390 0.000020 0.000016 0.000019 0.000334 0.000009 0.000022
Mitochondria 0.001178 0.001027 0.001614 0.002114 0.001139 0.000978 0.002726 0.001740 0.001150 0.000985 0.001865 0.001952
Mitotic Spindle 0.000396 0.000028 0.000085 0.000642 0.000037 0.001299 0.000143 0.001513 0.000138 0.001116 0.000098 0.001019
None 0.001747 0.000768 0.000592 0.001036 0.009373 0.001487 0.000690 0.000827 0.007240 0.001384 0.000614 0.000945
Nuclear Periphery 0.000026 0.000029 0.000031 0.000200 0.000023 0.000062 0.000045 0.000083 0.000024 0.000057 0.000034 0.000149
Nuclear Periphery Foci 0.000073 0.000005 0.000004 0.000182 0.000323 0.000545 0.000007 0.000030 0.000253 0.000467 0.000004 0.000116
Nucleolus 0.073306 0.059621 0.054466 0.040939 0.072620 0.046231 0.072716 0.036556 0.072812 0.048159 0.058583 0.039040
Nucleus 0.910099* 0.928981* 0.922735* 0.939324* 0.900910* 0.938164* 0.878598* 0.948110* 0.903480* 0.936842* 0.912778* 0.943131*
Peroxisomes 0.008249 0.005331 0.011924 0.003467 0.007480 0.002182 0.032263 0.003835 0.007695 0.002636 0.016512 0.003626
Vacuole 0.000228 0.000209 0.000213 0.001255 0.000785 0.000724 0.000486 0.000354 0.000630 0.000650 0.000274 0.000865
Vacuole Periphery 0.000446 0.000239 0.000184 0.000804 0.000362 0.000403 0.000218 0.000372 0.000385 0.000379 0.000192 0.000617

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.18 -4.40 -5.70 -5.69 -0.96 1.19 -8.34 -2.19 -2.82 7.33 1.23 -7.16 -5.37 -5.09 3.06
Bud Neck -2.05 -9.29 -7.54 -5.70 1.35 -5.68 -7.66 -6.07 -1.61 4.67 -6.07 -11.71 -9.49 -4.84 3.79
Bud Site 1.08 -2.65 -2.97 -3.88 -1.51 -0.22 -0.63 0.81 0.88 2.12 -0.40 -0.16 -0.47 0.10 -0.51
Cell Periphery -0.52 -0.76 -4.63 -4.24 -4.05 0.41 1.43 0.92 1.17 -1.43 0.21 1.38 0.40 0.41 -3.63
Cytoplasm 1.01 1.44 -2.76 -4.22 -4.75 1.66 3.32 2.70 1.30 -2.42 1.40 3.40 2.53 1.16 -4.87
Cytoplasmic Foci 1.28 1.14 -0.33 -2.80 -2.57 0.59 -0.18 -0.38 -0.87 -0.28 1.04 1.76 -0.78 -1.93 -2.73
Eisosomes 1.96 -1.65 1.10 -1.06 2.29 0.67 -1.14 2.32 2.54 6.14 0.47 -0.12 2.79 3.20 3.23
Endoplasmic Reticulum -1.60 -0.81 -0.96 1.06 -0.29 -1.08 -0.92 9.11 4.16 3.12 -1.63 1.96 7.05 3.89 2.96
Endosome 0.80 1.26 -1.47 -1.55 -1.58 -1.20 1.39 1.09 2.44 -1.52 -1.39 1.57 -0.80 0.27 -1.68
Golgi 1.11 0.47 -0.26 -2.45 -1.33 -1.31 -0.27 0.89 1.71 2.29 -1.27 0.76 0.42 1.47 -0.54
Lipid Particles 1.14 1.08 0.54 -1.66 -1.47 -1.92 -0.89 -0.41 1.90 0.23 -1.85 1.29 0.11 1.86 -1.59
Mitochondria 1.25 -4.40 -7.93 -8.37 -3.61 1.21 -7.36 -5.55 -5.22 4.13 1.46 -8.00 -10.05 -8.37 -0.71
Mitotic Spindle 1.04 0.91 -0.24 -2.64 -2.36 -2.05 -1.64 -1.78 -0.18 -1.61 -1.61 0.54 -2.10 -0.03 -2.55
None 1.23 1.45 0.83 -1.10 -1.93 4.57 5.17 5.07 1.68 -1.13 4.58 5.37 5.06 1.22 -2.36
Nuclear Periphery -0.34 -1.00 -3.78 -3.69 -3.65 -2.84 -3.62 -3.19 -1.01 -1.89 -2.83 -2.83 -4.61 -3.17 -4.17
Nuclear Periphery Foci 1.47 1.49 -0.85 -2.05 -2.06 -0.62 1.44 1.30 1.69 -2.16 -0.71 1.60 0.85 1.34 -2.33
Nucleolus 1.69 2.11 5.19 2.76 2.18 6.20 -0.20 8.05 2.60 3.70 6.68 2.09 9.42 2.89 3.77
Nucleus -2.15 -1.10 -3.82 -1.10 -2.14 -6.93 1.61 -8.30 -1.98 -4.67 -7.31 -0.91 -8.75 -1.27 -4.46
Peroxisomes 2.25 -2.06 4.28 1.75 4.91 6.47 -4.04 3.93 -3.49 4.66 7.57 -4.43 5.54 -2.95 6.63
Vacuole 0.42 0.32 -2.64 -2.73 -2.72 0.28 1.85 1.95 1.84 0.58 -0.17 3.27 -1.02 -0.91 -2.75
Vacuole Periphery 0.99 1.27 -1.23 -2.61 -2.87 -0.85 3.98 -0.31 0.09 -1.71 0.06 3.05 -1.71 -1.85 -3.33
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Histone H1, linker histone with roles in meiosis and sporulation; decreasing levels early in sporulation may promote meiosis, and increasing levels during sporulation facilitate compaction of spore chromatin; binds to promoters and within genes in mature spores; may be recruited by Ume6p to promoter regions, contributing to transcriptional repression outside of meiosis; suppresses DNA repair involving homologous recombination
Localization
Cell Percentages nucleus (93%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-2

Hho1

Hho1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Hho1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available