Standard name
Human Ortholog
Description Peptidyl-prolyl cis/trans-isomerase; also activates the phosphotyrosyl phosphatase activity of protein phosphatase 2A (PP2A); regulates G1 phase progression, the osmoresponse, microtubule dynamics; subunit of the Tap42p-Pph21p-Rrd2p complex; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.97 0.99 0.99 0.99 0.98 0.91 0.84 0.88 0.81 0.76 0.68 0.7 1.0 0.99 1.0 0.94 0.96 0.96 0.85 0.91 0.93 0.93 0.92 0.91
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.06 0 0 0 0 0.18 0.27 0.27 0.34 0.38 0.47 0.35 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0.05 0 0 0.06 0 0.1 0 0 0 0.1 0.1 0.06 0.06 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0 0
Bud 0 0 1 0 0 2 1 3 1 6 5 8 0 0 0 0 1 0 1 1 1 0 2 4
Bud Neck 0 0 2 0 2 0 0 0 1 0 0 1 0 0 0 0 0 0 0 1 1 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 2 2 2 2 2 1 3 1 0 2 1 0 2 23 13 17 0 0 0 0 0 0
Cytoplasm 181 424 238 224 352 282 317 259 242 259 197 250 148 164 203 637 435 507 172 394 223 131 200 197
Endoplasmic Reticulum 0 1 1 0 0 0 0 1 1 0 3 0 0 1 0 19 12 7 0 0 0 0 2 1
Endosome 0 2 0 0 0 0 0 0 0 0 1 1 0 0 0 3 0 1 0 4 0 0 1 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 2 3 0 0 0 1
Mitochondria 11 3 0 2 12 56 103 79 102 129 136 124 0 0 0 1 1 2 4 7 5 3 1 4
Nucleus 0 2 0 0 0 2 2 2 5 4 5 4 2 0 0 6 4 1 0 3 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 1 0 1 1 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 0 1 0 1 0 0 1 0 0 0 1 0 0 0 3 0 0 2 1
Vac/Vac Membrane 1 2 1 1 3 3 18 6 10 22 6 35 0 0 0 70 44 32 12 2 3 0 1 1
Unique Cell Count 186 429 240 226 359 311 378 296 300 342 291 357 148 165 203 679 455 527 202 433 241 141 218 217
Labelled Cell Count 193 434 245 229 372 347 444 351 366 421 353 427 151 166 205 760 512 568 202 433 241 141 218 217


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.2 5.4 5.1 4.9 5.1 4.4 4.3 4.9 4.2 4.3 3.9 4.5 5.6 6.0 6.0 8.7 9.0 8.5 5.4 5.7 6.5
Std Deviation (1e-4) 0.7 1.0 1.1 1.1 1.4 1.2 1.3 1.8 2.0 1.0 0.9 1.2 1.1 0.9 1.3 1.3 1.4 1.5 1.3 1.3 1.8
Intensity Change (Log2) – – – -0.06 0.0 -0.22 -0.25 -0.05 -0.27 -0.25 -0.38 -0.18 0.13 0.24 0.23 0.76 0.81 0.73 0.08 0.17 0.36


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 2.1 1.7 2.0
Cytoplasm -0.1 -1.1 -4.3 -6.1 -5.2 -6.8 -7.9 -9.4 -9.0 1.1 0.3 1.3 -3.3 -2.6 -2.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 2.2 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 8.7 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 3.0 0 0 3.7 0 4.7 0 0 0 4.9 4.7 3.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.5075 2.0593 1.8343 1.496 1.4783 1.7636 0.2603 0.2602 0.3925 0.6107 1.0483 0.5714 -0.6238 0.1281 0.0521 0.4334 -0.3219 -0.0162
Actin 0.0041 0.0019 0.0005 0.0015 0.0002 0.0025 0.0076 0.0063 0.008 0.0532 0.0019 0.001 0.0003 0.0134 0.0007 0.0004 0.002 0.0021
Bud 0.0004 0.0013 0.002 0.0034 0.0001 0.0008 0.0019 0.0069 0.002 0.0005 0.0002 0.0006 0.0011 0.0028 0.0007 0.0005 0.0002 0.0011
Bud Neck 0.0021 0.0009 0.0002 0.0003 0.0002 0.005 0.0026 0.0009 0.001 0.0069 0.0004 0.0065 0.0001 0.0004 0.0002 0.0002 0.0006 0.006
Bud Periphery 0.0009 0.0008 0.0011 0.0039 0 0.0012 0.0026 0.0098 0.0018 0.0016 0.0003 0.0008 0.0037 0.0059 0.002 0.002 0.0004 0.0015
Bud Site 0.0012 0.0109 0.003 0.0006 0.0001 0.0008 0.0044 0.0315 0.0156 0.0053 0.0009 0.0003 0.0018 0.0063 0.0007 0.0002 0.0002 0.0007
Cell Periphery 0.0002 0.0003 0.0001 0.0001 0 0.0001 0.0003 0.0012 0.0002 0.0015 0.0001 0.0001 0.0003 0.0003 0.0002 0.0002 0.0001 0.0002
Cytoplasm 0.2053 0.3272 0.2471 0.2663 0.3066 0.3258 0.3823 0.4361 0.4897 0.3586 0.1691 0.5 0.3666 0.3912 0.362 0.218 0.3085 0.4251
Cytoplasmic Foci 0.0077 0.0105 0.0062 0.0078 0.006 0.0131 0.016 0.0101 0.0096 0.0052 0.0081 0.011 0.0143 0.0281 0.0212 0.018 0.0191 0.0292
Eisosomes 0.0001 0.0002 0.0001 0.0001 0 0 0.0001 0.0001 0.0002 0.0006 0.0001 0 0.0001 0.0003 0.0001 0.0001 0 0.0001
Endoplasmic Reticulum 0.0029 0.0022 0.0014 0.0016 0.0022 0.0016 0.0043 0.0018 0.0054 0.0127 0.0019 0.0018 0.0034 0.0029 0.0025 0.0038 0.0012 0.0031
Endosome 0.0026 0.004 0.0017 0.0017 0.003 0.0032 0.01 0.0027 0.0057 0.0038 0.0383 0.0033 0.0195 0.026 0.0275 0.035 0.0307 0.0218
Golgi 0.0003 0.0005 0.0001 0.0001 0.0001 0.0002 0.0011 0.0003 0.0016 0.0009 0.0033 0.0006 0.0018 0.011 0.0083 0.0092 0.0097 0.0116
Lipid Particles 0.0004 0.0003 0.0002 0.0002 0.0002 0.0003 0.0032 0.0002 0.0013 0.0005 0.0319 0.0011 0.0138 0.0046 0.0029 0.0034 0.007 0.0033
Mitochondria 0.0005 0.0006 0.0005 0.0006 0.0002 0.0004 0.0018 0.0006 0.0014 0.0009 0.0021 0.0009 0.0247 0.046 0.0962 0.1385 0.0744 0.0378
None 0.7604 0.6191 0.7222 0.6985 0.6721 0.6287 0.5208 0.4732 0.423 0.5173 0.6085 0.4536 0.5167 0.4335 0.4556 0.5518 0.4818 0.4334
Nuclear Periphery 0.0017 0.0016 0.0011 0.0018 0.001 0.0011 0.0159 0.0013 0.0078 0.0097 0.0513 0.0017 0.0042 0.0016 0.001 0.002 0.0009 0.0009
Nucleolus 0.0006 0.0007 0.0007 0.0005 0.0001 0.0003 0.0013 0.0006 0.0006 0.0007 0.0076 0.0003 0.0012 0.0005 0.0003 0.0004 0.0002 0.0003
Nucleus 0.0041 0.0082 0.0056 0.005 0.0055 0.0061 0.0116 0.0082 0.0147 0.01 0.0192 0.0103 0.0128 0.0043 0.003 0.0021 0.0103 0.0041
Peroxisomes 0.0004 0.0007 0.0003 0.0004 0.0001 0.0005 0.001 0.0005 0.0012 0.0003 0.0038 0.0006 0.0035 0.0137 0.0078 0.0035 0.0465 0.0132
Punctate Nuclear 0.0027 0.0068 0.0054 0.0042 0.0014 0.0076 0.008 0.0056 0.0076 0.0054 0.0428 0.0046 0.0013 0.0024 0.0029 0.0007 0.0023 0.0025
Vacuole 0.0011 0.0013 0.0006 0.001 0.0008 0.0006 0.0021 0.0019 0.0013 0.0036 0.0053 0.0006 0.0061 0.0038 0.0031 0.0069 0.0023 0.0013
Vacuole Periphery 0.0002 0.0002 0.0001 0.0002 0.0001 0.0001 0.001 0.0002 0.0004 0.0007 0.0028 0.0002 0.0028 0.001 0.0012 0.0029 0.0015 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 12.8065 6.411 3.398 13.5765 9.2983 3.0718 11.5753 16.5625 14.5179 13.835
Translational Efficiency 0.9216 2.0019 3.0861 0.9956 1.195 5.1177 1.0044 0.7588 1.071 1.0247

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1177 802 2673 123 1991 1569 2203 1246 3168 2371 4876 1369

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 625.51 725.78 800.01 965.38 666.17 727.14 816.40 918.76 651.06 726.68 807.42 922.95
Standard Deviation 72.58 87.09 103.31 173.09 71.32 90.21 111.80 158.75 74.43 89.17 107.54 160.65
Intensity Change Log 2 — 0.214499 0.354985 0.626064 — 0.126343 0.293386 0.463798 — 0.169707 0.323544 0.544657

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000274 0.000482 0.000094 0.001768 0.000131 0.000545 0.000121 0.000686 0.000184 0.000524 0.000106 0.000784
Bud Neck 0.024853 0.021799 0.003517 0.002188 0.011071 0.024869 0.004275 0.006912 0.016191 0.023831 0.003860 0.006487
Bud Site 0.007135 0.018441 0.007263 0.005374 0.002669 0.017803 0.015766 0.031195 0.004328 0.018019 0.011105 0.028875
Cell Periphery 0.000212 0.000106 0.000095 0.000330 0.000106 0.000149 0.000152 0.000146 0.000146 0.000134 0.000120 0.000162
Cytoplasm 0.410913* 0.482902* 0.521994* 0.286072* 0.539864* 0.510276* 0.591036* 0.550683* 0.491955* 0.501017* 0.553188* 0.526909*
Cytoplasmic Foci 0.303944* 0.244142* 0.005970 0.027239 0.177193 0.177036 0.015733 0.019581 0.224285* 0.199735* 0.010381 0.020269
Eisosomes 0.000243 0.000099 0.000015 0.000165 0.000104 0.000100 0.000025 0.000037 0.000156 0.000100 0.000019 0.000048
Endoplasmic Reticulum 0.000953 0.000868 0.001195 0.010955 0.000885 0.001245 0.000887 0.001671 0.000910 0.001117 0.001056 0.002505
Endosome 0.019025 0.016442 0.000639 0.012686 0.006016 0.017347 0.001622 0.009006 0.010849 0.017041 0.001083 0.009336
Golgi 0.005588 0.007429 0.000048 0.038405 0.001225 0.004419 0.000120 0.006808 0.002846 0.005437 0.000081 0.009647
Lipid Particles 0.014982 0.005023 0.000404 0.005053 0.005118 0.003779 0.000569 0.002482 0.008783 0.004200 0.000478 0.002713
Mitochondria 0.017440 0.009571 0.000484 0.000276 0.003433 0.008376 0.000421 0.004564 0.008637 0.008780 0.000455 0.004179
Mitotic Spindle 0.000835 0.010203 0.003653 0.002981 0.001852 0.014370 0.004849 0.069688 0.001474 0.012960 0.004194 0.063695
None 0.003058 0.003444 0.005259 0.002655 0.003383 0.003212 0.006302 0.005772 0.003262 0.003291 0.005730 0.005492
Nuclear Periphery 0.000440 0.000288 0.001471 0.001956 0.000477 0.000530 0.000890 0.000955 0.000463 0.000448 0.001209 0.001045
Nuclear Periphery Foci 0.000421 0.000511 0.000345 0.007330 0.000306 0.000563 0.000465 0.002020 0.000349 0.000546 0.000399 0.002497
Nucleolus 0.001988 0.001291 0.000219 0.000323 0.000700 0.001936 0.000325 0.001147 0.001178 0.001718 0.000267 0.001073
Nucleus 0.127317 0.102023 0.417057* 0.212216* 0.210481* 0.140855* 0.313667* 0.154995* 0.179584* 0.127720 0.370345* 0.160137*
Peroxisomes 0.012231 0.012746 0.000113 0.000513 0.003367 0.009996 0.000165 0.002230 0.006660 0.010926 0.000136 0.002076
Vacuole 0.045807 0.060143 0.030053 0.381167* 0.030971 0.060360 0.042183 0.122561 0.036483 0.060287 0.035533 0.145796
Vacuole Periphery 0.002340 0.002046 0.000114 0.000348 0.000648 0.002232 0.000427 0.006860 0.001276 0.002169 0.000255 0.006275

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.19 3.86 -2.50 -1.47 -3.22 -3.32 -0.53 -4.02 0.75 -4.29 -3.84 1.49 -4.25 0.41 -5.40
Bud Neck 1.11 10.55 10.52 8.53 0.59 -6.97 6.65 5.84 10.83 -1.35 -4.62 12.50 10.91 13.19 -1.82
Bud Site -5.37 0.85 0.43 5.47 -0.42 -9.22 -6.11 -6.72 1.14 -0.81 -10.51 -5.09 -5.88 1.80 -2.65
Cell Periphery 5.87 6.59 0.15 -3.80 -4.35 -3.93 -1.47 -0.14 3.81 1.41 1.21 3.09 3.31 2.05 -0.63
Cytoplasm -5.49 -5.69 7.67 10.34 10.37 3.59 1.43 11.84 7.72 10.44 -0.85 -0.14 9.42 9.37 9.85
Cytoplasmic Foci 5.99 46.93 43.05 27.84 -3.87 0.00 37.76 38.26 33.85 2.36 4.41 57.35 55.81 43.80 -2.56
Eisosomes 10.87 18.56 8.45 -0.95 -8.70 0.46 16.17 12.93 8.18 -5.63 7.71 24.20 18.70 9.64 -11.58
Endoplasmic Reticulum 0.37 -5.34 -7.39 -7.47 -6.60 -1.01 -3.67 -7.03 -2.49 -5.01 -0.88 -6.50 -10.05 -5.80 -6.78
Endosome 1.28 11.16 6.75 6.25 -4.43 -8.49 7.79 3.64 10.59 -3.23 -5.33 13.72 8.60 13.00 -5.03
Golgi -1.33 7.66 -0.10 0.18 -1.01 -4.15 6.27 -1.00 2.62 -2.91 -3.73 9.46 0.72 3.15 -2.82
Lipid Particles 7.27 11.72 9.14 2.52 -7.46 3.11 13.65 7.89 5.47 -2.68 7.93 16.09 12.11 6.36 -3.74
Mitochondria 3.02 7.27 7.37 7.14 4.19 -3.79 4.40 2.15 5.63 -2.61 -0.02 8.39 6.69 7.60 -2.48
Mitotic Spindle -3.74 -4.64 -1.74 -0.33 -1.26 -5.58 -2.68 -9.08 -5.41 -8.21 -6.76 -4.15 -9.40 -5.79 -8.54
None -0.44 -3.09 -0.16 0.09 1.38 0.22 -3.24 -3.87 -4.06 -0.83 0.04 -3.99 -4.77 -4.63 -1.52
Nuclear Periphery 3.55 -15.62 -8.02 -8.55 -2.36 -0.63 -12.37 -15.57 -13.15 -7.12 0.17 -18.54 -18.90 -17.54 -2.87
Nuclear Periphery Foci -1.02 -1.31 -7.09 -6.94 -6.98 -2.98 -5.29 -7.22 -5.02 -5.47 -3.06 -4.78 -9.11 -7.44 -7.96
Nucleolus 1.39 3.59 3.42 4.90 -1.59 -3.08 5.39 1.00 3.30 -1.21 -1.68 4.84 2.82 3.89 -1.51
Nucleus 3.65 -46.76 -4.32 -5.66 14.01 11.41 -20.62 -2.36 -11.62 15.36 11.05 -44.96 -7.01 -14.65 26.06
Peroxisomes -0.35 11.00 10.81 8.94 -3.15 -7.34 8.38 5.86 10.80 -2.11 -5.02 13.59 11.27 13.58 -2.33
Vacuole -4.15 -3.40 -16.38 -15.67 -15.97 -11.53 -13.12 -29.06 -23.85 -23.09 -11.44 -12.48 -31.37 -27.18 -27.59
Vacuole Periphery 0.79 6.84 6.59 7.72 -2.19 -3.37 2.39 -1.77 0.34 -2.21 -2.56 7.59 -0.73 0.54 -2.40
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Peptidyl-prolyl cis/trans-isomerase; also activates the phosphotyrosyl phosphatase activity of protein phosphatase 2A (PP2A); regulates G1 phase progression, the osmoresponse, microtubule dynamics; subunit of the Tap42p-Pph21p-Rrd2p complex; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages cytoplasm (32%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Rrd2

Rrd2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rrd2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available