Standard name
Human Ortholog
Description Kinesin-related motor protein involved in mitotic spindle positioning; stabilizes microtubules by targeting Bik1p to the plus end; functions as a microtubule polymerase and catastrophe inhibitor in vitro; Kip2p levels are controlled during the cell cycle
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.07 0.06 0.24 0.15 0.14 0 0.12 0.08 0 – 0 0.08 0.05 0.05 0 0.22 0.25 0.24 0.08 0.09 0 0.1 0.13 0.15
Bud 0.09 0.07 0.08 0.06 0.08 0.11 0.14 0.1 0.1 – 0.1 0.15 0.05 0 0 0.05 0.06 0 0.05 0.06 0 0.15 0.13 0.15
Bud Neck 0 0 0.12 0 0.07 0.06 0 0.07 0 – 0 0.08 0 0 0 0 0 0 0.06 0.12 0.06 0.21 0.07 0.09
Bud Site 0 0 0.05 0.07 0 0.05 0 0 0.06 – 0.05 0.07 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Cytoplasm 0.16 0.27 0.18 0.31 0.41 0.2 0.24 0.25 0.16 – 0.15 0.13 0.13 0.3 0.27 0.09 0.12 0 0.05 0.1 0.07 0.1 0.12 0.12
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0.05 0 0 0 0.05 0 0.05 0 0 0 0 0 0
Endosome 0.23 0.16 0 0 0 0.06 0 0 0 – 0 0 0.19 0.33 0.31 0.2 0.12 0.19 0.2 0.18 0.16 0 0.09 0.07
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.19 0.19 0.29 0 0 0 0 0 0
Mitochondria 0.26 0.36 0 0.18 0.09 0.38 0.39 0.28 0.72 – 0.68 0.47 0.4 0.06 0.11 0.08 0.19 0.05 0.09 0.14 0.2 0.16 0.16 0.14
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Peroxisomes 0.1 0.06 0 0 0 0 0 0 0 – 0 0 0.12 0.21 0.24 0.06 0 0.1 0.05 0 0 0 0.09 0.06
SpindlePole 0.23 0.08 0.53 0.32 0.34 0.29 0.29 0.4 0.17 – 0.17 0.34 0.11 0.18 0.16 0.26 0.12 0.29 0.29 0.17 0.3 0.09 0.14 0.15
Vac/Vac Membrane 0.06 0.05 0 0 0 0 0 0 0 – 0 0 0 0 0 0.07 0.12 0.1 0 0 0 0.05 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 14 14 55 34 28 10 41 26 9 – 6 18 4 6 1 19 4 5 19 31 13 4 16 25
Bud 20 16 19 15 16 30 47 33 27 – 28 35 4 4 6 4 1 0 11 19 6 6 16 26
Bud Neck 4 1 28 10 14 18 15 23 9 – 6 18 0 0 0 0 0 0 16 41 21 8 9 15
Bud Site 5 3 12 16 4 14 13 9 16 – 13 16 3 1 2 1 0 0 – – – – – –
Cell Periphery 0 0 2 1 1 1 1 0 0 – 1 1 0 1 0 1 1 0 0 0 0 0 0 0
Cytoplasm 33 62 42 72 84 57 84 82 43 – 41 31 10 39 37 8 2 0 13 32 23 4 14 19
Endoplasmic Reticulum 3 8 6 7 4 6 4 3 8 – 1 11 2 4 3 4 0 1 0 0 0 0 1 2
Endosome 48 37 5 6 3 16 9 7 2 – 2 3 14 43 42 17 2 4 52 60 53 1 11 12
Golgi 0 1 1 1 0 0 0 0 0 – 0 0 0 0 0 16 3 6 1 1 2 0 2 0
Mitochondria 54 83 8 43 18 107 135 92 198 – 185 110 30 8 15 7 3 1 24 46 68 6 19 23
Nucleus 2 2 7 5 1 7 12 5 3 – 7 12 0 2 1 1 0 0 0 2 0 0 0 0
Nuclear Periphery 1 1 0 1 0 2 0 0 0 – 2 1 1 0 0 1 0 0 1 1 0 0 0 0
Nucleolus 8 3 0 0 1 5 8 3 3 – 3 4 3 0 3 2 1 0 1 4 12 0 0 0
Peroxisomes 21 15 2 8 4 9 4 6 5 – 4 3 9 28 32 5 0 2 11 10 11 1 10 9
SpindlePole 49 19 124 74 71 80 99 134 47 – 45 78 8 24 22 22 2 6 75 58 103 3 17 26
Vac/Vac Membrane 12 11 6 1 2 4 4 3 4 – 3 2 3 2 1 6 2 2 7 14 7 1 1 1
Unique Cell Count 211 232 234 233 207 279 345 334 275 272 232 75 132 135 85 16 21 260 339 347 41 124 171
Labelled Cell Count 274 276 317 294 251 366 476 426 374 347 343 91 162 165 114 21 27 260 339 347 41 124 171


Microtubule, SpindlePole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.4 5.4 5.5 5.0 5.5 4.3 4.4 4.7 3.9 – 3.6 4.1 5.0 5.5 5.5 9.1 8.9 9.1 – 5.0 5.1
Std Deviation (1e-4) 0.7 0.8 0.6 0.8 0.9 1.0 0.7 1.0 1.0 – 0.9 0.7 0.7 1.0 1.3 1.2 1.1 0.9 – 1.7 1.5
Intensity Change (Log2) – – – -0.15 -0.01 -0.35 -0.32 -0.24 -0.51 – -0.62 -0.44 -0.14 -0.01 0.01 0.71 0.7 0.72 – -0.15 -0.11

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -2.5 -2.7 0 0 0 0 – 0 0 -3.5 -4.7 -5.9 -0.2 0 0
Bud -0.7 -0.2 0 0 0 0 – 0 0 -0.8 -1.9 -1.4 -1.0 0 0
Bud Neck -3.0 -1.9 0 0 0 0 – 0 0 -3.1 -4.1 -4.2 -3.3 0 0
Bud Site 0.8 -1.8 0 0 0 0 – 0 0 0 0 -1.8 0 0 0
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 3.3 5.3 0.7 1.8 1.9 -0.7 – -0.9 -1.4 -0.9 2.6 2.1 -1.9 0 0
Endoplasmic Reticulum 0.3 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Endosome 0.3 0 0 0 0 0 – 0 0 0 8.3 8.0 5.6 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 5.2 2.3 0 0 0 0 – 0 0 8.4 1.2 2.9 0 0 0
Nucleus -0.6 0 -0.3 0.3 0 0 – -0.3 1.2 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 6.8 7.3 0 0 0
SpindlePole -4.6 -3.9 0 0 0 0 – 0 0 -6.4 -6.5 -6.9 -4.3 -3.1 -2.1
Vacuole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.7596 -0.2324 -0.3933 -0.0445 -0.2381 -0.2944 0.1481 0.8703 0.8587 1.1295 1.0292 0.8487 -0.21 0.0467 0.1416 0.4022 0.4114 0.1336
Actin 0.0356 0.0181 0.0303 0.0175 0.0264 0.0177 0.04 0.0348 0.0322 0.0158 0.0344 0.0135 0.014 0.0246 0.0231 0.0678 0.0033 0.0186
Bud 0.0008 0.0026 0.002 0.0058 0.0015 0.0009 0.0009 0.0061 0.0038 0.0012 0.0018 0.0009 0.0005 0.0023 0.0023 0.0008 0.0017 0.0006
Bud Neck 0.0151 0.0035 0.0426 0.0623 0.0032 0.0389 0.0062 0.006 0.0797 0.12 0.0078 0.0342 0.0075 0.0106 0.0833 0.0573 0.0008 0.0293
Bud Periphery 0.0009 0.0029 0.0031 0.0042 0.0016 0.0014 0.0016 0.0053 0.0047 0.0012 0.0026 0.001 0.0006 0.0023 0.0032 0.0022 0.0014 0.0019
Bud Site 0.0164 0.0645 0.0339 0.0085 0.0027 0.0029 0.0116 0.1042 0.0462 0.0114 0.0042 0.004 0.0212 0.0842 0.0165 0.0017 0.0016 0.0013
Cell Periphery 0.0005 0.0006 0.0006 0.0002 0.0002 0.0003 0.0004 0.0009 0.0004 0.0001 0.0003 0.0001 0.0008 0.0005 0.001 0.0005 0.0001 0.0002
Cytoplasm 0.0342 0.1917 0.1179 0.1159 0.0136 0.0411 0.0262 0.1014 0.1066 0.0606 0.0353 0.0404 0.0354 0.1576 0.1087 0.0119 0.033 0.0348
Cytoplasmic Foci 0.323 0.2704 0.3311 0.3646 0.3109 0.3478 0.3511 0.2736 0.3249 0.3814 0.2823 0.3046 0.3372 0.2567 0.37 0.3556 0.3633 0.3513
Eisosomes 0.0008 0.0004 0.0004 0.0001 0.0003 0.0002 0.0003 0.0003 0.0003 0.0001 0.0002 0.0001 0.0002 0.0003 0.0011 0.0006 0 0.0003
Endoplasmic Reticulum 0.0066 0.0032 0.0033 0.0042 0.0024 0.0027 0.0015 0.0027 0.0026 0.0016 0.0023 0.0007 0.0039 0.0034 0.0033 0.0011 0.0005 0.0009
Endosome 0.1341 0.0804 0.1075 0.0994 0.146 0.086 0.1132 0.1065 0.0835 0.0739 0.1506 0.0833 0.1375 0.0702 0.08 0.0923 0.1938 0.0556
Golgi 0.0287 0.0157 0.0219 0.03 0.0488 0.0315 0.0357 0.027 0.0248 0.0245 0.066 0.0349 0.026 0.0132 0.0212 0.0222 0.0839 0.0239
Lipid Particles 0.1013 0.0323 0.0259 0.0186 0.0702 0.0671 0.0674 0.0136 0.0197 0.0229 0.0199 0.0559 0.0894 0.0416 0.0238 0.0089 0.0262 0.0793
Mitochondria 0.0103 0.0166 0.0238 0.0067 0.0148 0.034 0.0241 0.0065 0.0157 0.0132 0.0323 0.0266 0.0177 0.0118 0.0124 0.054 0.0132 0.0246
None 0.1123 0.1581 0.1343 0.1131 0.0327 0.0376 0.0635 0.0589 0.0778 0.0394 0.0154 0.0183 0.0675 0.2104 0.1367 0.1122 0.0126 0.0539
Nuclear Periphery 0.0115 0.0018 0.002 0.0023 0.002 0.0029 0.0049 0.0043 0.0029 0.0009 0.0031 0.0009 0.0153 0.0009 0.0017 0.0009 0.0004 0.0003
Nucleolus 0.0037 0.0017 0.001 0.0004 0.0005 0.0015 0.0047 0.0015 0.0012 0.0005 0.0003 0.0006 0.0016 0.0007 0.001 0.0007 0.0005 0.0008
Nucleus 0.0021 0.0057 0.0023 0.0012 0.0007 0.0023 0.006 0.0019 0.0016 0.0006 0.0011 0.0008 0.0062 0.0013 0.0017 0.0006 0.0005 0.0005
Peroxisomes 0.1406 0.1158 0.0895 0.1335 0.3132 0.2632 0.2162 0.2236 0.155 0.2183 0.3301 0.3663 0.1885 0.0934 0.0928 0.1577 0.2507 0.3041
Punctate Nuclear 0.0133 0.0062 0.0165 0.0073 0.0054 0.0132 0.0182 0.0158 0.0121 0.0084 0.0035 0.0102 0.0122 0.01 0.0062 0.0454 0.0015 0.0157
Vacuole 0.0063 0.0067 0.0082 0.0033 0.0017 0.0051 0.0049 0.0042 0.0034 0.0028 0.0041 0.0018 0.0147 0.0035 0.0083 0.0043 0.0092 0.0015
Vacuole Periphery 0.0021 0.001 0.0018 0.0009 0.001 0.0014 0.0015 0.001 0.001 0.0012 0.0025 0.0009 0.0021 0.0005 0.0015 0.0014 0.0018 0.0006

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.0231 19.5322 12.7683 13.4138 13.1527 8.319 21.6298 23.9609 16.5661 12.9163
Translational Efficiency 0.9409 0.7318 0.9388 0.7606 0.5722 0.7516 0.7609 0.6075 0.7492 0.6603

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1695 1226 1842 1207 1857 417 50 249 3552 1643 1892 1456

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 718.77 786.86 1037.22 1011.49 767.61 806.23 1092.55 1057.60 744.30 791.78 1038.68 1019.38
Standard Deviation 79.61 100.67 125.99 130.15 82.88 101.75 139.08 122.92 84.92 101.30 126.66 130.11
Intensity Change Log 2 — 0.130577 0.529120 0.492880 — 0.070818 0.509254 0.462349 — 0.100025 0.518895 0.477193

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001742 0.003589 0.009444 0.013300 0.003268 0.002480 0.003974 0.003773 0.002540 0.003308 0.009299 0.011671
Bud Neck 0.055020 0.031383 0.018678 0.016462 0.046437 0.038180 0.022980 0.018393 0.050533 0.033108 0.018791 0.016792
Bud Site 0.063060 0.055308 0.139372 0.234189 0.051346 0.058061 0.112858 0.206695 0.056936 0.056007 0.138671 0.229487
Cell Periphery 0.000261 0.000165 0.000094 0.000144 0.000233 0.000428 0.000262 0.000088 0.000246 0.000232 0.000099 0.000135
Cytoplasm 0.072872 0.078614 0.085237 0.117100 0.068267 0.074621 0.058405 0.077913 0.070465 0.077600 0.084528 0.110399
Cytoplasmic Foci 0.267948 0.289366 0.093532 0.106058 0.282248 0.260679 0.078120 0.126813 0.275424 0.282085 0.093125 0.109608
Eisosomes 0.000119 0.000128 0.000037 0.000038 0.000139 0.000131 0.000122 0.000029 0.000130 0.000129 0.000040 0.000037
Endoplasmic Reticulum 0.000229 0.000374 0.000713 0.000655 0.000438 0.000292 0.001734 0.000209 0.000338 0.000353 0.000740 0.000579
Endosome 0.106712 0.117319 0.030754 0.060582 0.138420 0.175028 0.079940 0.068554 0.123289 0.131966 0.032054 0.061945
Golgi 0.063363 0.062090 0.008971 0.012942 0.061880 0.055563 0.008267 0.011236 0.062588 0.060433 0.008952 0.012650
Lipid Particles 0.014323 0.011618 0.002150 0.001636 0.012524 0.011042 0.029020 0.001113 0.013383 0.011472 0.002860 0.001547
Mitochondria 0.066850 0.042428 0.005127 0.008892 0.060792 0.049799 0.007979 0.002659 0.063683 0.044298 0.005203 0.007826
Mitotic Spindle 0.038680 0.062920 0.442392 0.291751 0.050832 0.054431 0.270796 0.307336 0.045033 0.060766 0.437858 0.294416
None 0.002703 0.000668 0.000354 0.000133 0.000910 0.000383 0.000238 0.000067 0.001766 0.000596 0.000350 0.000122
Nuclear Periphery 0.000076 0.000139 0.000300 0.000289 0.000123 0.000086 0.000416 0.000194 0.000100 0.000125 0.000303 0.000272
Nuclear Periphery Foci 0.001123 0.000953 0.001798 0.001176 0.001241 0.000410 0.006386 0.000946 0.001185 0.000815 0.001920 0.001137
Nucleolus 0.002601 0.001275 0.000838 0.000301 0.001969 0.001172 0.001951 0.000256 0.002270 0.001249 0.000867 0.000293
Nucleus 0.003070 0.004134 0.007221 0.001217 0.005004 0.002802 0.015344 0.000707 0.004081 0.003796 0.007436 0.001130
Peroxisomes 0.228623 0.218433 0.127353 0.084860 0.197793 0.172416 0.202898 0.118670 0.212505 0.206754 0.129349 0.090642
Vacuole 0.008709 0.016729 0.024950 0.043164 0.013207 0.036997 0.095853 0.053040 0.011061 0.021873 0.026823 0.044853
Vacuole Periphery 0.001918 0.002367 0.000684 0.005110 0.002928 0.005000 0.002456 0.001309 0.002446 0.003036 0.000731 0.004460

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.54 -8.82 -6.05 -4.75 -1.52 1.16 -0.70 -0.32 -1.05 0.30 -1.67 -7.76 -5.57 -4.94 -0.96
Bud Neck 6.30 11.12 12.69 6.57 3.47 1.68 4.21 9.81 4.89 0.76 6.23 13.95 16.48 8.18 3.61
Bud Site 1.62 -12.55 -18.70 -19.60 -9.52 -0.97 -2.76 -8.27 -7.34 -2.30 0.24 -15.50 -21.67 -20.87 -9.62
Cell Periphery 4.25 8.28 5.99 2.08 -2.67 -0.76 -0.89 6.04 1.33 3.12 0.20 9.02 7.12 1.63 -1.69
Cytoplasm -0.94 -4.89 -9.22 -7.99 -5.21 -0.70 0.36 -2.84 -2.00 -1.88 -1.51 -6.09 -10.46 -8.30 -4.85
Cytoplasmic Foci -2.30 28.08 23.10 25.08 -3.26 1.76 12.18 14.80 9.88 -1.82 -0.94 39.04 30.87 26.86 -4.07
Eisosomes -1.11 10.53 10.80 12.43 1.29 0.66 -0.19 13.54 8.06 4.19 -0.01 15.69 16.94 14.65 2.86
Endoplasmic Reticulum -2.57 -8.46 -2.14 -1.22 2.91 1.88 -2.84 1.58 -0.17 3.03 -0.43 -7.72 -1.46 -1.29 3.78
Endosome -1.72 18.64 10.84 11.65 -6.58 -3.55 3.42 9.14 9.57 0.81 -1.65 27.63 16.67 15.22 -7.19
Golgi 0.55 24.60 21.85 18.12 -2.53 1.39 21.97 21.48 10.03 -0.17 1.01 34.97 30.42 20.55 -2.51
Lipid Particles 1.39 8.12 8.82 7.56 3.75 0.53 -0.75 10.77 3.56 1.44 1.31 10.38 13.46 8.22 3.31
Mitochondria 4.91 15.96 14.77 10.19 -1.63 1.57 11.44 17.24 7.37 1.33 5.11 22.53 20.91 12.28 -1.18
Mitotic Spindle -5.09 -43.46 -24.56 -21.05 10.40 -0.32 -4.33 -11.31 -10.70 -1.20 -3.75 -43.33 -26.64 -23.70 10.39
None 3.73 4.28 4.92 2.35 7.14 2.85 2.07 6.16 2.38 1.44 3.98 4.94 6.30 2.76 7.66
Nuclear Periphery -2.20 -10.84 -5.68 -3.69 4.76 2.10 -3.23 -3.76 -4.73 1.61 -1.20 -10.59 -5.86 -4.62 5.22
Nuclear Periphery Foci 0.28 -5.22 -0.84 -1.16 4.01 3.32 -1.94 -0.87 -4.46 1.90 1.10 -6.19 -1.07 -1.89 4.72
Nucleolus 3.01 2.85 4.91 3.29 4.24 2.02 -0.72 4.33 3.37 1.31 3.43 2.71 6.21 4.09 4.67
Nucleus -1.45 -8.08 1.56 2.23 8.53 2.46 -1.50 3.95 1.59 1.88 0.21 -7.49 3.84 2.47 8.80
Peroxisomes 1.10 16.26 21.27 18.27 5.81 2.07 0.67 9.26 5.33 2.55 0.85 17.73 24.78 18.75 5.71
Vacuole -4.93 -14.39 -14.89 -12.20 -4.68 -5.51 -3.48 -6.91 -4.68 0.68 -6.73 -14.32 -16.04 -12.38 -5.24
Vacuole Periphery -1.36 4.87 -2.56 -2.04 -4.27 -2.72 0.66 3.22 5.76 0.99 -1.65 6.21 -1.51 -0.70 -4.29
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Kinesin-related motor protein involved in mitotic spindle positioning; stabilizes microtubules by targeting Bik1p to the plus end; functions as a microtubule polymerase and catastrophe inhibitor in vitro; Kip2p levels are controlled during the cell cycle
Localization
Cell Percentages mitochondrion (17%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Kip2

Kip2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Kip2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available