Standard name
Human Ortholog
Description Protein that associates with mitochondrial ribosome; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; expression may be cell cycle-regulated
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0.06 0 0.05 0.06 0.05 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.08 0.07 0 0 0 0 0 0
Cytoplasm 0.15 0.08 0.06 0.14 0.09 0.06 0 0 0 0 0 0 0.5 0.62 0.6 0.28 0.2 0.26 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.07 0 0 0 0 0 0 0 0 0 0 0.05 0.09 0.05 0.08 0.05 0.07 0 0 0 0 0 0
Endosome 0.07 0 0.17 0 0.11 0 0 0.05 0 0 0 0 0.11 0.14 0.12 0.14 0.18 0.19 0.12 0.09 0.07 0.05 0.07 0.07
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.75 0.91 0.71 0.78 0.83 0.9 0.94 0.88 0.93 0.97 0.96 0.97 0.16 0 0.06 0.2 0.1 0.14 0.71 0.68 0.71 0.74 0.68 0.68
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.28 0.14 0.09 0 0.05 0 0 0 0 0 0.05 0 0.07 0.06 0.2 0.16 0 0 0.08 0 0 0
SpindlePole 0.06 0 0.09 0.06 0.05 0 0.06 0.08 0 0 0 0 0.05 0.06 0 0.14 0.13 0.16 0 0 0 0 0 0
Vac/Vac Membrane 0.1 0.07 0.07 0 0.06 0.07 0 0.06 0.08 0.06 0.07 0.05 0.13 0.1 0.08 0.2 0.2 0.13 0 0.09 0 0.07 0.08 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 0 0 0 0 0 0 0 0 0 0 9 2 3 3 1 2 1 3 16 1 5 15
Bud 5 3 16 14 10 24 41 29 18 20 6 20 1 3 0 4 9 11 0 0 2 1 1 2
Bud Neck 1 0 1 0 0 0 0 0 0 1 0 0 2 2 1 0 0 2 1 0 1 2 1 7
Bud Site 2 0 0 0 0 8 20 9 7 7 0 3 0 0 0 0 1 1 – – – – – –
Cell Periphery 2 0 20 9 4 4 5 2 3 6 1 1 5 5 5 23 21 16 0 0 3 0 0 1
Cytoplasm 24 9 26 32 25 30 19 25 11 15 15 11 117 130 134 80 51 57 1 1 2 12 10 6
Endoplasmic Reticulum 0 7 2 1 2 1 0 2 2 9 8 21 12 19 12 24 12 16 3 0 2 3 1 2
Endosome 11 0 69 7 31 4 3 27 3 1 0 0 25 29 28 40 45 42 25 9 33 12 18 22
Golgi 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 3 2 4 2 0 14 1 6 6
Mitochondria 117 97 290 185 241 435 602 523 440 629 433 553 37 3 14 58 26 30 157 77 322 205 188 230
Nucleus 3 0 1 3 5 13 11 16 9 8 3 6 2 1 3 5 5 1 1 0 0 1 1 2
Nuclear Periphery 2 0 2 0 0 4 1 4 10 10 18 21 0 0 0 0 0 0 2 0 2 0 0 3
Nucleolus 4 0 0 0 1 5 12 6 3 7 5 2 0 0 0 0 1 1 0 0 1 2 1 2
Peroxisomes 4 0 114 33 27 17 29 18 8 1 1 1 12 0 16 18 50 34 6 3 35 3 3 2
SpindlePole 9 1 38 14 14 15 40 48 18 17 5 9 11 13 9 41 33 36 3 1 5 4 6 5
Vac/Vac Membrane 15 8 28 3 18 33 22 33 40 37 31 27 31 21 18 57 49 29 8 10 1 20 22 20
Unique Cell Count 155 107 410 237 292 482 640 597 471 650 452 572 235 210 224 287 250 219 222 113 452 279 278 338
Labelled Cell Count 199 126 608 301 378 593 805 742 573 768 526 675 264 228 243 356 306 282 222 113 452 279 278 338


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.6 4.2 4.6 4.3 4.3 3.9 3.8 4.1 3.7 3.6 3.5 3.5 5.7 5.7 5.8 6.5 6.1 5.8 5.7 6.1 6.4
Std Deviation (1e-4) 0.4 0.5 1.5 1.6 1.6 1.6 1.4 1.8 1.0 1.0 0.9 0.8 0.9 0.9 1.0 1.7 2.0 1.6 1.3 1.7 1.8
Intensity Change (Log2) – – – -0.09 -0.07 -0.23 -0.28 -0.17 -0.28 -0.34 -0.38 -0.38 0.33 0.32 0.34 0.52 0.43 0.34 0.34 0.43 0.49

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 5.2 5.0 2.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.7661 1.6056 1.3731 1.6123 0.8173 1.5129 0.8168 0.1129 0.0935 -0.0027 0.9228 0.4855 -0.1433 -0.1312 -0.1453 -0.1715 -0.4283 -0.4041
Actin 0.0051 0.031 0.0182 0.0066 0.0211 0.0124 0.0783 0.023 0.0169 0.0349 0.0624 0.0258 0.0261 0.0103 0.0298 0.0043 0.0361 0.0274
Bud 0.0006 0.0028 0.0024 0.0115 0.0105 0.0012 0.0072 0.0045 0.0035 0.0034 0.0012 0.0013 0.0015 0.0047 0.0092 0.0082 0.004 0.0019
Bud Neck 0.0024 0.0021 0.0059 0.0036 0.0016 0.0116 0.0035 0.0022 0.004 0.0066 0.003 0.0066 0.0032 0.0015 0.0039 0.0022 0.0022 0.0079
Bud Periphery 0.0016 0.005 0.0074 0.049 0.0254 0.0054 0.0058 0.008 0.0064 0.0097 0.0016 0.0032 0.0032 0.0088 0.0115 0.0113 0.0146 0.0057
Bud Site 0.0091 0.0444 0.0207 0.0223 0.0115 0.0019 0.0332 0.0363 0.0338 0.0116 0.0413 0.0018 0.0086 0.0295 0.0295 0.0082 0.0037 0.0021
Cell Periphery 0.005 0.0021 0.0075 0.0037 0.0024 0.0034 0.0016 0.0034 0.005 0.0038 0.0009 0.0009 0.0016 0.0015 0.0019 0.0011 0.0008 0.0011
Cytoplasm 0.0371 0.0555 0.0555 0.1103 0.0354 0.0572 0.0425 0.1272 0.128 0.0979 0.067 0.0887 0.0408 0.0753 0.0641 0.0594 0.0854 0.0466
Cytoplasmic Foci 0.0914 0.1289 0.1002 0.1415 0.083 0.1235 0.1232 0.1285 0.1474 0.0966 0.0794 0.1552 0.156 0.1785 0.1198 0.1169 0.1657 0.1281
Eisosomes 0.0022 0.0016 0.0028 0.0005 0.0011 0.0007 0.0021 0.0017 0.0009 0.0006 0.0003 0.0003 0.0009 0.0005 0.0013 0.0004 0.0009 0.0005
Endoplasmic Reticulum 0.0025 0.0093 0.0068 0.0029 0.0038 0.0063 0.0082 0.0065 0.0064 0.0042 0.0219 0.0134 0.0062 0.0066 0.0035 0.0059 0.0018 0.0028
Endosome 0.1287 0.1081 0.1472 0.1541 0.1212 0.101 0.167 0.1465 0.1795 0.1026 0.2619 0.1592 0.2255 0.1684 0.1252 0.1701 0.1915 0.134
Golgi 0.0611 0.0799 0.0519 0.0765 0.043 0.0494 0.069 0.0769 0.0633 0.0519 0.1948 0.0788 0.0846 0.0966 0.0605 0.0444 0.1022 0.077
Lipid Particles 0.0478 0.0212 0.0191 0.0146 0.0193 0.0314 0.0629 0.0182 0.022 0.0544 0.0315 0.0323 0.0317 0.0113 0.0152 0.0302 0.0228 0.0157
Mitochondria 0.2548 0.344 0.3617 0.3088 0.3575 0.373 0.1837 0.1996 0.2264 0.2614 0.1888 0.2929 0.2666 0.2632 0.3246 0.35 0.2636 0.3845
None 0.2677 0.1221 0.1097 0.0536 0.1503 0.1645 0.1068 0.1562 0.0962 0.1258 0.0146 0.0775 0.0588 0.0832 0.1268 0.0956 0.0299 0.0709
Nuclear Periphery 0.0006 0.0012 0.0028 0.0006 0.0009 0.0006 0.0094 0.0018 0.0028 0.0021 0.0015 0.0041 0.009 0.002 0.0012 0.003 0.0005 0.0023
Nucleolus 0.0014 0.0005 0.002 0.0016 0.0009 0.0007 0.0026 0.0011 0.0011 0.0046 0.0002 0.0005 0.0008 0.0008 0.0042 0.002 0.0002 0.0006
Nucleus 0.0009 0.0008 0.0019 0.0019 0.001 0.0007 0.0031 0.0019 0.0019 0.0026 0.0007 0.001 0.0033 0.0012 0.0021 0.0052 0.0006 0.0016
Peroxisomes 0.0557 0.0305 0.0503 0.0198 0.0969 0.0405 0.0471 0.0374 0.0281 0.0791 0.0126 0.0423 0.054 0.0437 0.0535 0.0551 0.0632 0.0768
Punctate Nuclear 0.0005 0.0009 0.0009 0.0023 0.0017 0.0009 0.0192 0.001 0.0026 0.0043 0.0005 0.0011 0.0019 0.0009 0.0017 0.0103 0.001 0.0037
Vacuole 0.0188 0.0056 0.0196 0.0108 0.0074 0.0093 0.0194 0.0139 0.0189 0.035 0.0087 0.0077 0.0107 0.0079 0.007 0.0106 0.0058 0.0054
Vacuole Periphery 0.0048 0.0027 0.0056 0.0035 0.0042 0.0043 0.0041 0.004 0.0049 0.0069 0.005 0.005 0.0049 0.0037 0.0035 0.0056 0.0035 0.0035

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.4003 4.5772 2.8304 8.3951 9.4046 5.9703 9.4487 7.8089 8.9676 10.4349
Translational Efficiency 0.9728 1.0877 1.6569 0.5812 0.5877 1.0852 0.617 0.6738 0.6755 0.646

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2183 856 238 1634 2289 1953 150 222 4472 2809 388 1856

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 690.23 773.56 884.82 860.18 684.78 749.54 909.64 946.28 687.44 756.86 894.42 870.48
Standard Deviation 82.60 103.60 91.86 117.11 85.12 89.44 103.61 110.03 83.94 94.63 97.32 119.60
Intensity Change Log 2 — 0.164436 0.358307 0.317561 — 0.130365 0.409655 0.466627 — 0.147569 0.384108 0.393723

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000860 0.002758 0.005161 0.014929 0.001051 0.000787 0.003985 0.010733 0.000958 0.001388 0.004706 0.014427
Bud Neck 0.020760 0.023177 0.019139 0.030025 0.022952 0.018446 0.013859 0.037326 0.021882 0.019887 0.017097 0.030898
Bud Site 0.015030 0.034487 0.029609 0.127728 0.015863 0.020761 0.033028 0.114265 0.015456 0.024944 0.030931 0.126118
Cell Periphery 0.000289 0.000325 0.000422 0.000252 0.000435 0.000212 0.000386 0.000201 0.000364 0.000246 0.000408 0.000246
Cytoplasm 0.031169 0.027401 0.174424 0.144912 0.043183 0.026167 0.160594 0.158552 0.037318 0.026543 0.169077 0.146543
Cytoplasmic Foci 0.142625 0.152861 0.136783 0.146763 0.211068 0.145741 0.204347 0.171359 0.177658 0.147911 0.162903 0.149705
Eisosomes 0.000233 0.000180 0.000242 0.000196 0.000236 0.000131 0.000268 0.000191 0.000235 0.000146 0.000252 0.000195
Endoplasmic Reticulum 0.001764 0.000587 0.016579 0.006271 0.001996 0.000592 0.007334 0.002901 0.001883 0.000590 0.013005 0.005868
Endosome 0.070747 0.106610 0.031293 0.037041 0.066851 0.094000 0.036573 0.030033 0.068753 0.097843 0.033334 0.036203
Golgi 0.115549 0.143280 0.004648 0.026001 0.101325 0.126421 0.003771 0.008547 0.108268 0.131559 0.004309 0.023913
Lipid Particles 0.010379 0.004309 0.019289 0.003248 0.015897 0.006039 0.015568 0.003521 0.013203 0.005512 0.017851 0.003281
Mitochondria 0.511378 0.315125 0.005115 0.057932 0.419767 0.422703 0.007464 0.005428 0.464487 0.389920 0.006023 0.051652
Mitotic Spindle 0.006193 0.033260 0.036260 0.088767 0.006904 0.022814 0.029443 0.049503 0.006557 0.025997 0.033624 0.084070
None 0.000728 0.001048 0.001924 0.000535 0.000700 0.000608 0.001725 0.000721 0.000714 0.000742 0.001847 0.000557
Nuclear Periphery 0.000183 0.000139 0.003331 0.000874 0.000432 0.000180 0.001630 0.000497 0.000310 0.000168 0.002673 0.000829
Nuclear Periphery Foci 0.000200 0.000192 0.007702 0.000896 0.000336 0.000266 0.003967 0.001282 0.000270 0.000244 0.006258 0.000942
Nucleolus 0.000780 0.001568 0.008190 0.001162 0.000697 0.001078 0.004543 0.000862 0.000737 0.001227 0.006780 0.001126
Nucleus 0.004672 0.005263 0.314663 0.036133 0.006391 0.004479 0.205129 0.047620 0.005552 0.004718 0.272317 0.037507
Peroxisomes 0.030226 0.105654 0.038731 0.096912 0.035181 0.053873 0.098802 0.090583 0.032763 0.069652 0.061954 0.096155
Vacuole 0.020514 0.027314 0.143779 0.168626 0.033533 0.038356 0.164975 0.264800 0.027178 0.034991 0.151974 0.180129
Vacuole Periphery 0.015720 0.014462 0.002716 0.010797 0.015201 0.016349 0.002610 0.001074 0.015455 0.015774 0.002675 0.009634

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.75 -5.63 -11.89 -9.43 -5.75 1.16 -5.21 -4.11 -4.25 -2.62 -2.41 -7.13 -12.44 -11.95 -7.15
Bud Neck -0.87 0.27 -4.82 -2.70 -3.22 2.10 3.55 -1.63 -2.58 -3.33 1.19 1.80 -5.14 -5.98 -5.39
Bud Site -6.38 -3.84 -23.00 -15.50 -15.06 -2.83 -2.05 -7.46 -6.95 -4.96 -6.26 -4.00 -24.39 -21.01 -15.21
Cell Periphery -0.77 -3.56 2.65 2.38 5.76 1.14 0.25 1.29 0.82 3.26 1.15 -0.52 1.45 1.15 6.07
Cytoplasm 1.04 -10.96 -23.70 -22.65 1.06 6.28 -7.78 -7.97 -9.24 -0.05 5.22 -13.28 -24.46 -26.54 0.77
Cytoplasmic Foci -1.66 1.21 2.55 3.62 0.05 12.16 2.06 6.92 1.23 2.82 7.44 3.24 10.61 3.92 2.26
Eisosomes 2.68 -1.32 3.25 -0.01 4.57 5.71 -1.70 2.18 -2.70 3.60 6.97 -2.06 4.04 -3.76 6.05
Endoplasmic Reticulum 3.41 -8.99 -5.97 -8.20 6.07 4.88 -7.00 -4.27 -9.20 4.96 5.79 -10.63 -6.43 -8.86 6.35
Endosome -6.47 9.50 13.43 14.46 -0.44 -7.24 7.29 12.50 17.18 1.90 -9.43 12.01 17.76 22.72 0.07
Golgi -3.82 29.53 24.34 19.15 -7.87 -5.02 30.91 27.27 29.24 -1.19 -5.70 41.85 32.31 31.62 -8.91
Lipid Particles 5.22 -4.00 8.11 0.96 7.51 7.76 0.31 10.15 2.68 5.95 8.96 -2.83 13.48 3.67 9.55
Mitochondria 15.19 71.02 60.24 23.78 -13.63 -0.22 57.61 59.05 54.61 0.81 9.45 90.69 74.81 51.24 -12.86
Mitotic Spindle -7.33 -3.50 -17.20 -9.38 -6.45 -7.79 -2.90 -4.69 -2.92 -2.10 -10.71 -4.47 -17.87 -12.52 -8.00
None -0.84 -2.80 1.02 1.44 3.27 0.42 -2.44 0.41 -0.03 2.64 -0.09 -3.67 1.03 0.93 4.01
Nuclear Periphery 0.91 -7.39 -9.98 -9.92 5.15 1.96 -5.55 -2.53 -6.27 4.24 2.03 -8.55 -7.79 -10.74 5.78
Nuclear Periphery Foci 0.24 -7.35 -10.80 -11.43 6.54 0.54 -6.49 -5.87 -6.04 4.10 0.33 -9.08 -10.78 -9.70 7.82
Nucleolus -1.45 -3.50 -2.90 -0.01 3.16 -1.86 -3.56 -0.99 1.15 3.41 -2.22 -4.33 -3.47 -0.78 3.81
Nucleus -0.57 -16.82 -16.40 -15.41 14.24 2.07 -10.17 -6.62 -6.85 7.25 1.09 -19.33 -17.59 -17.66 15.88
Peroxisomes -11.81 -1.36 -12.64 3.34 -6.92 -5.92 -3.32 -3.51 -1.39 0.82 -12.61 -3.39 -12.89 -2.29 -3.67
Vacuole -2.81 -13.35 -33.45 -30.51 -4.78 -1.87 -10.09 -16.60 -16.33 -5.67 -4.27 -16.22 -35.75 -33.71 -5.03
Vacuole Periphery 0.82 16.27 5.90 3.41 -5.79 -1.07 15.82 19.95 19.48 2.66 -0.35 22.49 7.77 7.27 -5.87
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein that associates with mitochondrial ribosome; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; expression may be cell cycle-regulated
Localization
Cell Percentages mitochondrion (95%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Mrx4

Mrx4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mrx4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available