Standard name
Human Ortholog
Description Component of the Rpd3L histone deacetylase complex; relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter; contains a PHD finger domain
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.09 0 0 0 0.05 0 0 0 0 0.11 0.14 0.17 0.09 0.09 0.07 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.16 0.06 0.06 0 0 0.08 0.09 0.09 0.16 0.18 0.14 0.14 0 0 0 0.11 0 0.07 0 0 0 0 0 0
Nucleus 0.86 0.9 0.89 0.84 0.87 0.79 0.74 0.69 0.65 0.62 0.63 0.61 0.83 0.8 0.76 0.8 0.82 0.89 0.77 0.81 0.72 0.62 0.66 0.62
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.44 0.29 0.31 0.21 0.2 0.35 0.38 0.44 0.53 0.52 0.51 0.6 0.19 0.17 0.19 0 0 0 0.16 0.12 0.19 0.26 0.22 0.19
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0.05 0.09
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Bud 0 0 0 0 0 0 0 3 3 4 2 2 0 0 0 1 0 0 0 4 0 0 4 5
Bud Neck 0 0 0 0 0 2 1 4 1 0 1 1 0 0 1 0 0 0 0 1 0 0 0 0
Bud Site 0 0 0 0 0 5 5 3 15 22 17 25 1 2 2 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 2 6 10 13 7 7 9 20 8 6 9 10 30 68 83 23 11 7 0 0 1 0 1 1
Endoplasmic Reticulum 0 0 0 0 0 2 1 0 0 1 0 0 0 1 0 4 5 1 0 0 1 0 0 1
Endosome 0 0 0 0 1 0 0 0 0 1 0 0 0 2 4 9 2 1 2 3 1 1 1 2
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 2 1 2
Mitochondria 27 16 13 2 9 30 41 38 59 92 49 60 3 5 1 27 4 7 0 1 2 0 1 5
Nucleus 147 249 206 118 215 285 339 306 233 320 217 263 218 377 378 201 97 87 136 240 176 87 180 189
Nuclear Periphery 0 1 1 2 0 2 5 3 4 2 9 2 2 2 0 2 1 0 0 0 0 1 0 1
Nucleolus 75 80 71 29 50 125 175 194 191 268 176 259 51 79 92 3 0 0 27 36 45 36 59 57
Peroxisomes 0 0 0 0 0 0 0 0 0 0 1 0 1 3 5 0 1 0 1 0 0 0 1 0
SpindlePole 1 0 0 0 0 0 0 2 1 1 1 1 3 5 5 1 1 1 1 1 1 1 3 4
Vac/Vac Membrane 1 4 2 0 2 1 4 0 1 3 0 0 1 1 3 12 4 3 3 3 8 4 13 27
Unique Cell Count 170 277 232 140 247 361 459 442 360 514 346 430 263 470 496 250 119 98 178 296 245 140 273 306
Labelled Cell Count 253 356 303 164 284 459 580 573 516 720 482 623 310 545 574 283 126 107 178 296 245 140 273 306


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.4 7.3 7.5 7.3 7.4 6.5 6.3 6.6 6.1 6.0 6.4 6.2 8.0 7.4 7.5 5.7 6.8 7.2 7.3 7.3 8.0
Std Deviation (1e-4) 1.4 1.6 2.2 1.8 2.0 2.0 2.0 1.9 1.6 1.8 2.2 1.9 2.3 2.4 2.5 1.3 1.6 1.3 2.2 2.0 1.8
Intensity Change (Log2) – – – -0.03 -0.02 -0.2 -0.25 -0.19 -0.28 -0.31 -0.22 -0.27 0.09 -0.01 0.01 -0.39 -0.13 -0.05 -0.03 -0.04 0.1

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 3.1 3.2 3.4 3.7 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.9 -0.9 -1.7 -1.8 0.1 -1.4 0 -1.1 -1.4 2.9 4.0 4.7 2.1 1.8 1.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -2.0 -1.0 1.2 1.5 1.4 3.9 4.5 3.3 3.3 -2.8 -3.6 0 2.1 -0.9 0.5
Nucleus -1.3 -0.6 -3.1 -4.5 -5.6 -6.5 -7.4 -6.9 -7.5 -1.9 -2.9 -4.0 -2.5 -1.9 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus -2.1 -2.6 1.0 2.0 3.4 5.4 5.5 4.8 7.3 -2.9 -4.2 -3.6 -8.9 -6.8 -6.2
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 2.6 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.2695 2.2973 2.4818 1.7437 1.6932 2.2245 4.5264 3.8159 3.6983 3.285 3.2212 3.7297 5.5534 5.2963 4.6846 3.9617 5.5709 4.1802
Actin 0.0107 0 0.0167 0.0007 0.015 0.0003 0.0174 0 0.017 0 0.0032 0.0041 0.0105 0.004 0.0258 0 0.0022 0.0139
Bud 0.0002 0.0001 0.0006 0.0001 0.0014 0.0001 0.0007 0 0.0004 0 0.0001 0 0.0004 0.0002 0.0002 0 0.0002 0.0002
Bud Neck 0.0008 0.0002 0.0006 0.0001 0.0049 0.0009 0.0028 0.0001 0.0006 0.0001 0.0023 0.0006 0.0005 0.0002 0.0001 0.0002 0.0005 0.0007
Bud Periphery 0.0005 0.0002 0.001 0.0001 0.0045 0.0001 0.0018 0 0.0011 0 0.0001 0.0001 0.0007 0.0001 0.0002 0 0.0003 0.0002
Bud Site 0.0022 0.0002 0.0076 0.0005 0.0033 0.0001 0.0031 0.0001 0.0016 0 0.0002 0.0001 0.0008 0.0048 0.0003 0.0002 0.0013 0.0003
Cell Periphery 0.0001 0.0002 0.0005 0 0.0005 0.0001 0.0004 0 0.0003 0 0.0003 0 0.0005 0.0001 0 0 0.0002 0
Cytoplasm 0.0011 0.0001 0.0025 0.0006 0.0007 0 0.0024 0 0.0027 0 0.0013 0.0001 0.0193 0.0025 0.0003 0.0001 0.0197 0.0013
Cytoplasmic Foci 0.0078 0 0.0025 0.033 0.0024 0.0001 0.0049 0 0.005 0 0.0004 0.0002 0.0164 0.0114 0.008 0 0.0428 0.0031
Eisosomes 0.0001 0 0.0002 0 0.0004 0 0.0002 0 0.0002 0 0.0055 0.0001 0.0001 0 0.0001 0 0.0002 0
Endoplasmic Reticulum 0.0004 0 0.001 0.0004 0.0033 0 0.0033 0 0.001 0 0.0008 0.0012 0.0038 0.0013 0.0007 0 0.0065 0.0003
Endosome 0.0134 0.0001 0.0063 0.0217 0.0213 0.0002 0.0113 0 0.0033 0 0.0006 0.0009 0.042 0.0011 0.0089 0.0001 0.0624 0.0083
Golgi 0.0023 0 0.0021 0.007 0.0063 0.0003 0.0034 0 0.0021 0 0.0006 0.0009 0.0174 0.0013 0.014 0 0.0179 0.0074
Lipid Particles 0.0052 0.0001 0.0033 0.0319 0.0076 0.0006 0.0079 0 0.0093 0 0.0012 0.0015 0.0139 0.0026 0.0074 0.0001 0.0079 0.0114
Mitochondria 0.0028 0.0038 0.0141 0.0007 0.0298 0.0098 0.0065 0 0.0082 0.0002 0.0007 0.0004 0.0304 0.0007 0.0027 0.0002 0.0222 0.0044
None 0.001 0.0001 0.0019 0.0003 0.0017 0 0.0035 0 0.0021 0 0.034 0.0002 0.0175 0.0015 0.0002 0 0.0069 0.0002
Nuclear Periphery 0.0035 0.0006 0.0052 0.0017 0.0321 0.0001 0.0133 0.0002 0.0043 0.0004 0.0067 0.0014 0.0234 0.0018 0.0005 0.0015 0.0015 0.0015
Nucleolus 0.0676 0.0741 0.0356 0.0456 0.2903 0.1533 0.0572 0.0366 0.034 0.0392 0.1505 0.0962 0.0319 0.0338 0.0161 0.0675 0.181 0.0863
Nucleus 0.865 0.9181 0.8875 0.8299 0.5559 0.8317 0.8386 0.961 0.8915 0.9587 0.7642 0.8888 0.7286 0.9146 0.8979 0.9256 0.6154 0.8477
Peroxisomes 0.0085 0 0.0009 0.0064 0.0022 0.0015 0.003 0 0.0077 0 0.0003 0.0011 0.0091 0.0129 0.0152 0 0.0068 0.001
Punctate Nuclear 0.0024 0.0005 0.0041 0.0189 0.0097 0.0005 0.0123 0.002 0.0046 0.0011 0.0266 0.0019 0.0122 0.0048 0.001 0.0043 0.002 0.0109
Vacuole 0.0033 0.0007 0.0044 0.0003 0.0032 0.0002 0.0037 0 0.0019 0 0.0002 0.0001 0.0143 0.0003 0.0001 0.0001 0.0014 0.0003
Vacuole Periphery 0.0011 0.001 0.0014 0.0002 0.0034 0 0.0022 0 0.0012 0 0.0002 0.0001 0.0061 0.0001 0.0001 0.0001 0.0009 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.6071 15.5641 17.8051 19.6177 20.6926 18.1261 19.0154 19.6937 22.87 17.7414
Translational Efficiency 2.1551 2.3756 1.9019 2.2418 1.6056 1.4651 1.6273 2.0007 1.6585 1.5658

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2091 1051 185 1854 1954 1513 1102 773 4045 2564 1287 2627

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 779.33 857.75 1208.51 1143.35 861.45 890.97 1114.11 1086.32 819.00 877.35 1127.68 1126.57
Standard Deviation 97.94 153.87 175.43 182.03 121.73 142.97 166.72 192.90 117.47 148.44 171.24 187.11
Intensity Change Log 2 — 0.138323 0.632923 0.552961 — 0.048610 0.371053 0.334610 — 0.091917 0.501371 0.442448

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000204 0.000740 0.001669 0.000765 0.000351 0.000687 0.000974 0.001001 0.000275 0.000709 0.001073 0.000834
Bud Neck 0.005544 0.013256 0.022864 0.031507 0.005465 0.011064 0.016477 0.024038 0.005506 0.011962 0.017395 0.029309
Bud Site 0.000823 0.002232 0.003908 0.002374 0.000609 0.001407 0.001346 0.003510 0.000720 0.001745 0.001714 0.002708
Cell Periphery 0.000051 0.000104 0.000101 0.000096 0.000298 0.000072 0.000050 0.000145 0.000170 0.000085 0.000057 0.000110
Cytoplasm 0.000572 0.001562 0.000238 0.000826 0.000665 0.001044 0.000475 0.003790 0.000617 0.001257 0.000441 0.001698
Cytoplasmic Foci 0.000186 0.001519 0.000089 0.000374 0.000087 0.000677 0.000125 0.001508 0.000138 0.001023 0.000120 0.000708
Eisosomes 0.000027 0.000043 0.000091 0.000050 0.000038 0.000047 0.000057 0.000050 0.000032 0.000045 0.000062 0.000050
Endoplasmic Reticulum 0.001661 0.003584 0.002126 0.001756 0.002433 0.003033 0.001580 0.002946 0.002034 0.003259 0.001659 0.002106
Endosome 0.000570 0.000747 0.000316 0.001016 0.000154 0.000694 0.000214 0.003139 0.000369 0.000716 0.000229 0.001641
Golgi 0.000201 0.000442 0.000237 0.000679 0.000087 0.000729 0.000263 0.000659 0.000146 0.000611 0.000259 0.000673
Lipid Particles 0.000060 0.000153 0.000132 0.000044 0.000059 0.000679 0.000030 0.001679 0.000060 0.000464 0.000044 0.000525
Mitochondria 0.001597 0.003061 0.002584 0.002727 0.000605 0.003446 0.001747 0.003360 0.001118 0.003288 0.001867 0.002913
Mitotic Spindle 0.001852 0.002546 0.001974 0.008304 0.001856 0.003057 0.001988 0.015996 0.001854 0.002848 0.001986 0.010567
None 0.002708 0.003484 0.001204 0.002070 0.001950 0.001758 0.001731 0.006473 0.002342 0.002465 0.001655 0.003366
Nuclear Periphery 0.000144 0.000246 0.000173 0.001302 0.000128 0.000480 0.000180 0.000861 0.000136 0.000384 0.000179 0.001172
Nuclear Periphery Foci 0.000240 0.000483 0.000092 0.000452 0.000154 0.000640 0.000090 0.000776 0.000198 0.000576 0.000090 0.000547
Nucleolus 0.070971 0.079573 0.104207 0.029160 0.084964 0.083641 0.078251 0.036855 0.077731 0.081974 0.081982 0.031424
Nucleus 0.911536 0.883138 0.852594 0.911691 0.899134 0.883722 0.891823 0.886590 0.905545 0.883483 0.886184 0.904305
Peroxisomes 0.000347 0.000811 0.004023 0.000382 0.000420 0.000999 0.001193 0.001082 0.000382 0.000922 0.001600 0.000588
Vacuole 0.000409 0.001279 0.000943 0.002697 0.000263 0.001106 0.000609 0.003327 0.000339 0.001177 0.000657 0.002882
Vacuole Periphery 0.000300 0.000995 0.000434 0.001729 0.000280 0.001016 0.000798 0.002214 0.000290 0.001008 0.000745 0.001872

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -12.62 -9.08 -12.95 -3.16 4.58 -3.52 -15.77 -15.34 -4.17 -0.17 -7.37 -19.66 -16.69 -4.20 3.22
Bud Neck -6.79 -7.71 -21.07 -12.23 -3.79 -8.26 -16.76 -10.90 -7.45 -3.59 -10.41 -18.30 -23.87 -16.12 -9.86
Bud Site -2.93 -2.60 -5.46 -0.98 1.02 -3.05 -7.05 -4.83 -3.15 -2.89 -4.00 -5.71 -7.83 -3.42 -2.75
Cell Periphery -2.45 -0.88 -2.92 0.72 -0.01 0.97 1.04 0.73 -2.81 -4.15 0.73 0.96 0.60 -1.01 -3.37
Cytoplasm -1.73 1.57 -1.50 1.24 -4.58 -1.29 -0.08 -3.70 -1.88 -3.76 -2.02 -0.03 -3.82 -0.07 -3.81
Cytoplasmic Foci -1.47 1.06 -0.78 1.35 -1.93 -2.21 -0.19 -3.10 -0.88 -2.99 -2.18 0.49 -2.94 1.23 -3.15
Eisosomes -7.22 -10.80 -12.46 -3.00 6.88 -3.29 -10.86 -5.60 -1.17 4.03 -7.14 -17.97 -12.32 -2.56 7.13
Endoplasmic Reticulum -7.52 -2.83 -2.54 5.85 1.02 -2.40 2.95 -1.96 0.07 -3.94 -6.74 0.57 -2.20 4.66 -2.80
Endosome -0.60 0.88 -0.55 0.09 -1.81 -3.29 -0.50 -2.74 -1.93 -2.65 -1.87 0.91 -2.70 -1.46 -3.49
Golgi -1.32 -0.85 -1.34 -0.29 -1.05 -2.46 -1.73 -2.61 0.74 -1.33 -2.68 -1.18 -2.21 0.43 -1.41
Lipid Particles -2.17 -1.39 -0.09 2.20 1.41 -2.14 0.43 -1.54 -0.58 -1.55 -2.39 -0.16 -1.54 0.38 -1.53
Mitochondria -1.42 -1.79 -2.44 0.18 -0.61 -3.84 -4.10 -6.59 0.39 -2.64 -3.45 -2.31 -5.83 0.53 -3.16
Mitotic Spindle -0.64 -0.97 -4.09 -3.45 -2.48 -1.14 -1.30 -4.32 -4.02 -3.72 -1.31 -1.55 -5.93 -5.30 -4.25
None -1.39 3.64 1.25 2.52 -2.38 0.44 0.08 -3.51 -3.64 -3.56 -0.39 1.60 -1.80 -1.39 -3.01
Nuclear Periphery -1.89 -1.63 -3.89 -3.45 -3.62 -2.04 -2.17 -3.75 -1.33 -3.13 -2.41 -2.31 -4.74 -3.17 -4.25
Nuclear Periphery Foci -1.36 0.98 -0.85 0.72 -2.64 -1.99 -0.08 -2.29 0.17 -2.28 -2.29 0.60 -2.14 0.82 -3.08
Nucleolus -2.38 -4.99 14.21 13.92 9.18 0.43 0.94 10.96 10.29 8.28 -1.63 -2.19 19.39 18.98 13.74
Nucleus 5.64 6.96 1.74 -3.73 -6.11 3.43 3.12 1.93 -0.21 -0.12 6.55 6.62 2.00 -3.45 -4.14
Peroxisomes -4.79 -7.59 -1.26 5.37 7.47 -2.90 -11.20 -4.25 0.17 1.81 -4.26 -11.89 -3.78 2.54 9.84
Vacuole -2.62 -3.10 -3.99 -2.37 -2.95 -3.50 -2.72 -3.78 -2.23 -2.60 -4.26 -2.89 -5.24 -3.18 -3.68
Vacuole Periphery -2.36 -0.99 -2.91 -0.65 -2.47 -2.82 -0.75 -2.05 -0.81 -1.20 -3.73 -0.79 -3.55 -1.01 -1.55
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Component of the Rpd3L histone deacetylase complex; relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter; contains a PHD finger domain
Localization
Cell Percentages nucleus (99%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Cti6

Cti6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cti6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available