Standard name
Human Ortholog
Description Protein required for nuclear envelope fusion during karyogamy; pheromone-regulated; peripheral protein of the nuclear membrane; interacts with Kar5p at the spindle pole body
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.99 0.97 0.99 0.97 0.94 0.89 0.83 0.85 – 0.8 0.7 0.68 0.99 0.99 1.0 – – – 0.87 0.86 0.73 0.79 0.77 0.78
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0 0 0 0 0.08 0.29 0.39 0.28 – 0.35 0.48 0.47 0 0 0 – – – 0.05 0 0.12 0.09 0.08 0.07
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 6 6 3 2 1 2
Bud 0 3 1 1 0 3 5 9 – 4 14 12 0 0 0 – – – 3 5 3 1 5 4
Bud Neck 4 3 3 0 3 3 2 5 – 2 4 6 2 2 1 – – – 3 0 2 2 1 1
Bud Site 0 0 0 0 0 0 1 1 – 1 2 4 0 0 0 – – – – – – – – –
Cell Periphery 2 1 1 1 0 2 0 1 – 1 0 2 4 0 2 – – – 2 1 3 1 0 1
Cytoplasm 613 424 232 173 264 257 298 287 – 313 236 303 246 394 449 – – – 546 376 164 156 143 197
Endoplasmic Reticulum 3 2 0 0 0 1 0 1 – 0 0 0 3 0 1 – – – 1 0 3 1 2 1
Endosome 1 0 0 1 3 0 0 0 – 0 0 0 0 1 0 – – – 8 6 2 1 3 3
Golgi 0 2 1 0 0 0 0 0 – 0 0 0 0 1 0 – – – 1 1 1 1 0 0
Mitochondria 5 11 3 2 23 85 139 95 – 137 163 206 0 0 0 – – – 33 15 26 17 14 18
Nucleus 0 1 0 1 5 1 5 9 – 6 3 5 1 1 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 2 0 0 0 0 0 0 – 0 1 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 1 0 1 0 0 0 0 – 2 1 0 0 0 0 – – – 0 0 0 0 0 1
Peroxisomes 0 0 0 0 1 0 0 0 – 1 1 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 1 1 0 2 3 2 3 7 – 8 8 18 0 0 0 – – – 4 7 4 0 0 5
Vac/Vac Membrane 0 1 0 0 0 0 0 0 – 4 1 0 0 1 2 – – – 8 4 3 5 7 9
Unique Cell Count 621 438 235 178 281 290 358 338 392 337 443 249 397 451 630 437 226 198 185 254
Labelled Cell Count 629 452 241 182 302 354 453 415 479 434 556 256 400 455 630 437 226 198 185 254


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.8 3.7 3.2 3.6 3.3 3.1 2.9 3.1 – 2.8 2.6 2.5 4.9 4.6 4.8 4.8 4.8 4.7 5.6 5.5 5.7
Std Deviation (1e-4) 0.5 0.7 0.7 2.0 1.6 1.4 1.9 2.0 – 1.5 1.6 1.2 1.2 1.4 1.3 1.3 1.6 1.3 2.2 2.0 2.2
Intensity Change (Log2) – – – 0.18 0.06 -0.04 -0.13 -0.03 – -0.18 -0.26 -0.32 0.64 0.56 0.6 0.6 0.6 0.59 0.82 0.81 0.85

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.5958 -0.5315 -0.6225 -1.0427 -0.385 -0.3543 1.897 1.3048 1.5355 2.8518 1.1541 1.4113 -0.2587 -0.6291 -0.3399 0.1286 -0.1271 -0.4762
Actin 0.0071 0.0003 0.0002 0.0001 0.0001 0.0003 0.0103 0.001 0.0167 0.0008 0.0016 0.0002 0.0292 0.0001 0.0006 0.0287 0.0005 0.0006
Bud 0.0023 0.0053 0.0011 0.0001 0 0.0007 0.0066 0.0055 0.0023 0.0023 0.0003 0.0003 0.0003 0.0018 0.0001 0.0008 0 0.0005
Bud Neck 0.0021 0.0002 0.0001 0.0162 0 0.0127 0.0005 0.0001 0.0003 0.0137 0.0003 0.0002 0.0309 0.0001 0.0002 0.0002 0.0001 0.0016
Bud Periphery 0.0049 0.0013 0.0005 0.0001 0 0.0007 0.0122 0.0062 0.0018 0.0021 0.0002 0.0004 0.0004 0.0008 0.0001 0.0008 0 0.0016
Bud Site 0.0023 0.0075 0.0012 0 0 0.0024 0.001 0.0113 0.003 0.0457 0.002 0 0.007 0.0042 0.0167 0.0009 0.0001 0.0003
Cell Periphery 0.0003 0.0001 0.0001 0 0 0.0001 0.0016 0.0004 0.0002 0.0046 0.0001 0 0.0002 0.0002 0.0001 0 0 0.0001
Cytoplasm 0.0108 0.007 0.0065 0.0043 0.0046 0.0123 0.0174 0.0121 0.0111 0.0175 0.0211 0.0222 0.0188 0.0272 0.0085 0.0236 0.0153 0.0283
Cytoplasmic Foci 0.0059 0.0028 0.0017 0.0097 0.0009 0.0026 0.0066 0.0023 0.0025 0.0034 0.0301 0.0027 0.0025 0.0054 0.0009 0.0127 0.038 0.006
Eisosomes 0.0003 0.0002 0.0002 0.0001 0.0002 0.0001 0.0002 0.0002 0.0004 0.0004 0.0002 0.0001 0.0002 0.0002 0.0001 0.0002 0 0.0001
Endoplasmic Reticulum 0.0022 0.0002 0.0002 0.0001 0.0001 0.0001 0.0177 0.0002 0.004 0.0653 0.0001 0.0005 0.0022 0.0009 0.0002 0.0011 0.0002 0.0002
Endosome 0.0029 0.0002 0 0.0001 0 0.0001 0.0084 0.0001 0.0043 0.001 0.0044 0.0003 0.0084 0.0006 0.0053 0.0123 0.03 0.0057
Golgi 0.0008 0.0001 0 0.0001 0 0 0.0011 0.0001 0.0012 0.0004 0.0095 0 0.0068 0.0001 0.0002 0.0043 0.0101 0.0035
Lipid Particles 0.0014 0.0002 0.0001 0.0002 0.0001 0.0001 0.0084 0.0003 0.0009 0.0007 0.0018 0.0002 0.0076 0.0011 0.0009 0.002 0.0275 0.0112
Mitochondria 0.0029 0.0003 0.0002 0.0001 0.0001 0.0001 0.0022 0.0013 0.0215 0.0012 0.0013 0.0003 0.0045 0.0001 0.0008 0.025 0.0014 0.0036
None 0.938 0.9594 0.9785 0.9651 0.9937 0.9621 0.8077 0.9556 0.9066 0.825 0.9175 0.9544 0.871 0.955 0.9561 0.8724 0.8587 0.924
Nuclear Periphery 0.0033 0.0005 0.0006 0.0001 0 0.0007 0.0295 0.0006 0.0079 0.0021 0 0.0017 0.0066 0.0003 0.0052 0.0033 0.0001 0.0004
Nucleolus 0.0008 0.0011 0.0009 0.0008 0.0001 0.0002 0.0022 0.0003 0.0005 0.0012 0.0001 0.0006 0.0001 0.0002 0.0003 0.0001 0 0.0007
Nucleus 0.0068 0.0037 0.0034 0.0003 0.0001 0.0031 0.0158 0.0005 0.0037 0.0009 0.0001 0.0037 0.0003 0.0008 0.0014 0.0009 0 0.0003
Peroxisomes 0.0013 0.0002 0.0001 0.0003 0 0.0001 0.0017 0.0004 0.0012 0.0003 0.0085 0.0001 0.0005 0.0001 0.0002 0.0063 0.0171 0.0085
Punctate Nuclear 0.0016 0.0089 0.0043 0.0023 0.0001 0.0015 0.0365 0.0008 0.0065 0.0004 0.0004 0.0115 0.0004 0.0005 0.0007 0.0033 0.0003 0.0022
Vacuole 0.0011 0.0002 0.0001 0.0001 0 0.0001 0.0109 0.0003 0.0022 0.0106 0.0002 0.0004 0.0005 0.0004 0.0007 0.0005 0.0003 0.0005
Vacuole Periphery 0.0008 0 0 0 0 0.0001 0.0017 0.0002 0.0013 0.0004 0 0.0002 0.0014 0 0.0007 0.0006 0.0001 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression – – – – – – – – – –
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression –
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
853 1832 126 1174 1009 1612 1631 1097 1862 3444 1757 2271

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 618.05 701.66 808.84 771.30 633.29 660.30 762.94 751.24 626.31 682.30 766.23 761.61
Standard Deviation 83.74 86.04 70.22 111.70 83.13 84.57 89.54 99.23 83.76 87.81 89.08 106.34
Intensity Change Log 2 — 0.183049 0.388131 0.319569 — 0.060255 0.268703 0.246408 — 0.122210 0.328925 0.283006

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000053 0.000177 0.000379 0.000803 0.000485 0.000421 0.000126 0.000922 0.000287 0.000291 0.000144 0.000860
Bud Neck 0.003919 0.029972 0.000941 0.007662 0.010333 0.049805 0.006016 0.008126 0.007395 0.039255 0.005652 0.007886
Bud Site 0.002134 0.010859 0.001278 0.028997 0.003375 0.014764 0.008237 0.026605 0.002807 0.012687 0.007738 0.027842
Cell Periphery 0.000259 0.000177 0.000313 0.000193 0.000227 0.000218 0.000104 0.000214 0.000242 0.000196 0.000119 0.000203
Cytoplasm 0.539538 0.455623 0.241978 0.452971 0.451370 0.351851 0.349800 0.471013 0.491760 0.407051 0.342068 0.461686
Cytoplasmic Foci 0.160879 0.192370 0.053571 0.018387 0.250819 0.277049 0.007345 0.032044 0.209617 0.232005 0.010660 0.024984
Eisosomes 0.000114 0.000105 0.000171 0.000046 0.000229 0.000266 0.000023 0.000058 0.000176 0.000180 0.000034 0.000051
Endoplasmic Reticulum 0.000309 0.000598 0.005154 0.002083 0.000721 0.000523 0.001264 0.001430 0.000532 0.000563 0.001543 0.001767
Endosome 0.004994 0.013414 0.008980 0.008044 0.016007 0.030634 0.001020 0.007163 0.010962 0.021474 0.001591 0.007618
Golgi 0.000741 0.002864 0.000158 0.005216 0.003098 0.008493 0.000067 0.001889 0.002019 0.005499 0.000074 0.003609
Lipid Particles 0.005940 0.005549 0.008915 0.001328 0.015663 0.014714 0.000707 0.001424 0.011209 0.009839 0.001296 0.001374
Mitochondria 0.001689 0.009363 0.000346 0.001768 0.005797 0.020649 0.000593 0.003203 0.003915 0.014645 0.000576 0.002461
Mitotic Spindle 0.000098 0.006900 0.000088 0.039317 0.002317 0.007499 0.007847 0.013611 0.001300 0.007181 0.007291 0.026900
None 0.013878 0.002906 0.002623 0.007016 0.004216 0.003794 0.005755 0.005260 0.008642 0.003321 0.005531 0.006168
Nuclear Periphery 0.000352 0.000550 0.001872 0.001646 0.000731 0.000497 0.001427 0.001000 0.000557 0.000525 0.001459 0.001334
Nuclear Periphery Foci 0.000350 0.000260 0.003110 0.001340 0.000385 0.000297 0.000293 0.000682 0.000369 0.000277 0.000495 0.001022
Nucleolus 0.001683 0.001616 0.002261 0.000636 0.001811 0.003208 0.000397 0.000534 0.001752 0.002361 0.000530 0.000587
Nucleus 0.233749 0.197648 0.571550 0.309711 0.180827 0.122259 0.583386 0.353945 0.205071 0.162361 0.582537 0.331078
Peroxisomes 0.001551 0.009369 0.001040 0.000312 0.005294 0.025801 0.000191 0.001510 0.003579 0.017060 0.000252 0.000891
Vacuole 0.027329 0.058312 0.094912 0.108985 0.045082 0.064504 0.025221 0.067200 0.036949 0.061210 0.030218 0.088801
Vacuole Periphery 0.000439 0.001369 0.000361 0.003541 0.001214 0.002755 0.000179 0.002167 0.000859 0.002018 0.000192 0.002877

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.50 -6.61 -2.56 -1.86 -0.05 0.15 0.71 -0.41 -0.85 -1.61 -0.03 0.33 -1.12 -1.71 -2.18
Bud Neck -13.70 4.43 -2.34 12.33 -6.80 -13.55 2.58 1.64 14.30 -0.69 -18.47 1.07 0.58 18.70 -0.56
Bud Site -6.09 0.44 -6.23 -2.31 -6.93 -6.77 -2.99 -5.99 -1.80 -4.23 -9.05 -3.52 -8.58 -2.90 -5.38
Cell Periphery 1.16 -1.08 1.98 1.36 6.85 0.13 1.96 0.69 1.19 -5.05 0.92 2.74 1.87 1.77 -3.66
Cytoplasm 8.22 14.52 15.63 9.21 -6.22 9.54 13.11 3.02 -5.79 -9.12 11.43 21.20 12.63 2.54 -8.99
Cytoplasmic Foci -4.18 13.13 25.93 36.99 5.76 -2.96 38.15 33.30 41.59 -11.06 -3.72 44.44 41.44 54.50 -8.51
Eisosomes 0.88 -4.30 5.35 10.38 9.14 -0.90 5.82 4.79 9.37 -10.66 -0.15 7.00 6.00 11.42 -7.37
Endoplasmic Reticulum -3.19 -6.79 -17.17 -13.99 4.07 2.21 -9.98 -7.34 -8.98 0.88 -0.50 -13.65 -16.94 -16.35 -0.15
Endosome -8.32 -3.78 0.92 8.41 4.20 -6.11 9.78 5.91 12.34 -4.36 -7.97 10.51 5.91 14.74 -5.02
Golgi -5.17 2.72 -1.42 1.16 -2.26 -4.32 3.74 2.10 7.20 -2.99 -5.23 4.33 0.76 6.09 -3.44
Lipid Particles 0.56 -2.84 6.60 11.65 7.98 0.54 10.30 9.77 13.20 -6.33 1.40 11.44 11.45 16.42 -0.37
Mitochondria -6.98 2.92 1.27 8.19 -4.59 -6.63 3.84 2.44 9.88 -3.14 -8.55 4.33 2.81 12.61 -3.85
Mitotic Spindle -4.85 -1.00 -7.80 -5.45 -7.76 -2.88 -2.63 -3.57 -1.40 -1.77 -5.04 -3.84 -8.32 -5.32 -5.55
None 5.81 5.93 4.69 -3.68 -3.88 0.41 -1.56 -0.07 -0.52 1.86 5.18 3.48 4.07 -2.40 1.30
Nuclear Periphery -2.52 -9.98 -19.96 -15.60 -2.61 2.24 -11.06 -6.13 -12.27 6.33 0.32 -18.04 -18.04 -18.97 -1.61
Nuclear Periphery Foci 1.73 -6.79 -6.23 -6.67 4.76 1.32 -0.92 -3.55 -4.01 -3.06 2.17 -5.11 -7.10 -7.75 -3.39
Nucleolus 0.03 -1.24 5.07 4.91 4.63 -2.18 5.41 4.85 4.89 -1.62 -1.81 6.89 6.84 6.50 -0.10
Nucleus 4.36 -12.14 -10.95 -16.09 7.64 8.56 -45.97 -18.72 -26.48 19.84 7.85 -47.82 -21.24 -29.54 25.79
Peroxisomes -9.99 2.20 7.00 12.11 7.64 -11.33 9.23 6.64 14.27 -3.26 -13.96 10.52 8.44 17.97 -2.86
Vacuole -11.34 -7.67 -23.89 -19.07 -5.18 -5.87 0.42 -12.48 -8.84 -12.52 -11.27 -4.43 -25.86 -20.24 -21.46
Vacuole Periphery -7.06 0.82 -1.70 0.01 -1.81 -4.93 7.47 -0.41 2.35 -2.56 -6.95 8.05 -1.42 1.59 -3.31
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein required for nuclear envelope fusion during karyogamy; pheromone-regulated; peripheral protein of the nuclear membrane; interacts with Kar5p at the spindle pole body
Localization
Cell Percentages cytoplasm (19%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Prm3

Prm3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Prm3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available