Standard name
Human Ortholog
Description Phosphatidylglycerol phospholipase C; regulates phosphatidylglycerol (PG) accumulation via a phospholipase C-type degradation mechanism; PG levels affect mitochondrial function; contains glycerophosphodiester phosphodiesterase motifs
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0
Bud 0 0 0 0 0 0 0 0.06 0.06 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.78 0.83 0.95 0.91 0.96 0.81 0.68 0.62 0.37 0.5 0.21 0.32 0.77 0.77 0.82 0.46 0.45 0.37 0.36 0.39 0.27 0.43 0.46 0.43
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0.11 0.07 0 0 0 0 0 0
Endosome 0 0.08 0 0 0 0 0 0 0 0 0 0 0.07 0.1 0.12 0.24 0.4 0.41 0.13 0.12 0.08 0.08 0.07 0.09
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.19 0.07 0.05 0.05 0 0.17 0.4 0.48 0.69 0.61 0.88 0.73 0 0 0 0.05 0.07 0.08 0.29 0.28 0.46 0.28 0.26 0.21
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0
SpindlePole 0 0 0 0.06 0 0 0 0 0 0 0 0 0.14 0.11 0.07 0.18 0.12 0.14 0.05 0.05 0 0.09 0.06 0.07
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0.15 0.1 0.14 0.05 0.06 0 0 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 0 0 0 0 1 0 0 1 0 0 1 1 0 0 0 0 10 2 2 6 15 10
Bud 3 2 0 1 0 0 9 13 11 6 4 6 0 0 0 1 0 4 2 0 0 3 6 9
Bud Neck 2 0 0 2 3 4 4 5 0 2 0 2 3 7 5 2 1 1 2 4 0 2 3 6
Bud Site 0 0 0 0 1 0 1 0 2 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 1 0 0 1 0 0 0 0 1 1 0 2 1 0 1 1 0 0 2 3
Cytoplasm 205 121 19 147 193 135 171 139 73 106 31 42 193 228 304 110 89 115 119 71 21 104 141 163
Endoplasmic Reticulum 6 2 0 1 2 6 0 0 0 0 2 0 4 1 0 24 21 22 8 3 1 2 3 6
Endosome 1 11 0 1 1 2 4 1 0 1 0 0 17 30 44 58 78 125 44 21 6 19 20 32
Golgi 0 0 0 1 0 0 0 0 0 0 0 0 1 2 0 3 1 0 1 1 0 0 0 1
Mitochondria 50 10 1 8 2 29 101 108 134 128 132 96 0 1 1 12 13 24 95 50 36 67 80 78
Nucleus 0 0 0 0 2 0 3 1 2 3 1 6 1 0 0 3 2 0 0 0 0 0 0 2
Nuclear Periphery 2 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 1 0 1 0 0
Nucleolus 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 1 1 0 0 1 1 1 0 1 6 26 3 0 1 2 3 2
SpindlePole 9 4 0 10 3 3 6 6 5 4 2 4 34 34 27 43 24 43 14 9 2 21 19 26
Vac/Vac Membrane 2 4 0 0 0 3 3 6 2 5 1 9 3 7 6 37 20 43 15 10 2 5 6 22
Unique Cell Count 262 146 20 162 200 167 252 226 195 211 150 132 251 297 372 241 197 308 332 181 80 242 311 379
Labelled Cell Count 281 154 20 172 208 182 303 281 230 257 173 168 259 313 387 296 257 403 332 181 80 242 311 379


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.2 4.3 4.4 4.6 4.6 3.6 3.5 3.9 3.1 3.5 3.1 3.5 5.4 5.4 5.4 6.6 6.1 5.7 5.2 5.3 5.6
Std Deviation (1e-4) 0.5 1.0 1.5 1.4 1.5 1.1 1.2 1.2 0.6 1.2 0.8 1.0 1.4 1.7 1.5 1.9 2.1 2.0 1.7 2.1 2.0
Intensity Change (Log2) – – – 0.05 0.05 -0.31 -0.35 -0.19 -0.53 -0.35 -0.5 -0.33 0.29 0.3 0.28 0.57 0.46 0.35 0.23 0.27 0.35

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.6914 -0.7493 -0.6116 -0.1382 -1.5097 -0.6261 1.1269 0.0806 0.1521 -0.133 -0.2119 -0.2865 -0.6544 -0.3968 -0.2222 -0.6104 -0.2626 -0.3034
Actin 0.0353 0.0027 0.0069 0.0403 0.0002 0.0011 0.0213 0.0018 0.0134 0.0126 0.0185 0.0011 0.0002 0.0021 0.0009 0.0013 0.0002 0.0004
Bud 0.0008 0.0005 0.0005 0.0015 0.0001 0.001 0.0015 0.0036 0.001 0.0002 0.0021 0.0002 0.0036 0.0057 0.0104 0.0032 0.0001 0.0054
Bud Neck 0.0129 0.0009 0.0123 0.0177 0.0004 0.0045 0.0103 0.0006 0.0039 0.009 0.0026 0.0059 0.0005 0.0019 0.0102 0.0005 0.0002 0.0011
Bud Periphery 0.0017 0.0007 0.001 0.0025 0.0001 0.0012 0.0037 0.001 0.0012 0.0002 0.0014 0.0009 0.0007 0.004 0.0036 0.002 0.0001 0.0013
Bud Site 0.0059 0.0096 0.0023 0.0162 0.0002 0.0031 0.0137 0.0085 0.0076 0.001 0.0115 0.0015 0.0064 0.0197 0.0052 0.0021 0.0002 0.0009
Cell Periphery 0.0007 0.0004 0.0003 0.001 0 0.0005 0.0014 0.0005 0.0007 0.0001 0.0003 0.001 0.0003 0.0011 0.0005 0.0002 0.0001 0.0003
Cytoplasm 0.0294 0.0376 0.0343 0.0191 0.0149 0.0273 0.0345 0.0385 0.0304 0.0115 0.0689 0.0424 0.0131 0.0367 0.0161 0.0275 0.0156 0.0262
Cytoplasmic Foci 0.1758 0.1137 0.1826 0.1722 0.2137 0.1543 0.1752 0.1653 0.1637 0.2293 0.2149 0.2102 0.1619 0.1487 0.1639 0.1926 0.1896 0.1837
Eisosomes 0.0008 0.0006 0.0003 0.0012 0 0.0003 0.0004 0.0002 0.0055 0.0001 0.0003 0.0001 0.0001 0.0004 0.0002 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.0035 0.0041 0.0045 0.0041 0.001 0.003 0.0074 0.0049 0.0058 0.0009 0.004 0.0033 0.0013 0.0045 0.0034 0.0023 0.0034 0.0031
Endosome 0.1575 0.1297 0.1215 0.0723 0.1034 0.1078 0.1365 0.1575 0.1349 0.0964 0.1118 0.1418 0.2183 0.1819 0.2016 0.234 0.2057 0.1865
Golgi 0.0134 0.0109 0.0114 0.0158 0.0117 0.0085 0.0185 0.0134 0.0118 0.0199 0.0196 0.0141 0.0281 0.0249 0.0348 0.0151 0.0241 0.0172
Lipid Particles 0.267 0.1492 0.2234 0.1221 0.4459 0.2521 0.2655 0.23 0.2354 0.2736 0.2217 0.2955 0.3943 0.1896 0.2969 0.211 0.2699 0.3589
Mitochondria 0.0095 0.0043 0.0085 0.0071 0.0033 0.009 0.0192 0.0071 0.0053 0.0071 0.0037 0.0215 0.0072 0.0049 0.0111 0.0033 0.0049 0.0044
None 0.1541 0.431 0.2459 0.4084 0.0098 0.2364 0.127 0.266 0.2462 0.1472 0.2105 0.114 0.0713 0.2239 0.0979 0.0838 0.1649 0.1031
Nuclear Periphery 0.0059 0.0105 0.0135 0.0083 0.0014 0.0101 0.0239 0.0072 0.0115 0.0076 0.0091 0.0077 0.0026 0.0086 0.0055 0.0078 0.0071 0.0043
Nucleolus 0.0239 0.0079 0.0056 0.0063 0.0006 0.0134 0.0046 0.0066 0.0045 0.0046 0.0025 0.0065 0.008 0.0163 0.0033 0.0041 0.002 0.0025
Nucleus 0.0093 0.0088 0.0083 0.0085 0.0005 0.0228 0.0309 0.0055 0.0099 0.0011 0.0147 0.005 0.0043 0.0112 0.0085 0.0082 0.0037 0.0035
Peroxisomes 0.0507 0.0277 0.0618 0.0296 0.1398 0.0663 0.0576 0.0278 0.0408 0.1235 0.0495 0.06 0.0455 0.05 0.0877 0.0866 0.0638 0.0553
Punctate Nuclear 0.0207 0.0336 0.0429 0.0358 0.0486 0.0684 0.0346 0.035 0.0544 0.0422 0.0268 0.0489 0.0207 0.0416 0.0272 0.1068 0.0135 0.0297
Vacuole 0.0192 0.0131 0.0097 0.0084 0.0035 0.0072 0.0098 0.0158 0.0098 0.01 0.0047 0.0144 0.0095 0.0195 0.0086 0.0061 0.0261 0.0097
Vacuole Periphery 0.0022 0.0025 0.0025 0.0018 0.0009 0.0019 0.0023 0.0031 0.0025 0.0019 0.0011 0.0039 0.0018 0.0027 0.0026 0.0015 0.0047 0.0024

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.1358 16.3375 21.9732 26.2708 23.6954 26.257 25.8107 29.6148 42.7387 28.9062
Translational Efficiency 3.463 2.946 2.2021 2.0687 1.9657 2.1546 2.2954 1.8413 1.6065 1.7818

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1817 643 2040 1606 1855 2089 888 1116 3672 2732 2928 2722

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 663.26 705.49 771.19 750.66 647.60 710.02 798.13 799.16 655.35 708.95 779.36 770.54
Standard Deviation 81.65 89.47 86.41 122.72 74.47 83.29 91.30 112.64 78.50 84.81 88.79 121.07
Intensity Change Log 2 — 0.089051 0.217512 0.178585 — 0.132757 0.301521 0.303381 — 0.110808 0.259626 0.241587

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000154 0.001363 0.000146 0.003305 0.000230 0.000419 0.000130 0.002174 0.000193 0.000642 0.000141 0.002841
Bud Neck 0.015538 0.018820 0.009398 0.020123 0.011223 0.025199 0.007776 0.017140 0.013358 0.023697 0.008906 0.018900
Bud Site 0.002038 0.009677 0.008212 0.044794 0.003081 0.014322 0.004791 0.020579 0.002565 0.013229 0.007174 0.034866
Cell Periphery 0.000136 0.000178 0.000194 0.000223 0.000133 0.000132 0.000215 0.000171 0.000134 0.000143 0.000200 0.000202
Cytoplasm 0.307426 0.121577 0.414500 0.319255 0.350156 0.196855 0.388372 0.369982 0.329012 0.179138 0.406576 0.340052
Cytoplasmic Foci 0.374765 0.436416 0.042940 0.155870 0.322229 0.339902 0.077152 0.114509 0.348225 0.362617 0.053316 0.138912
Eisosomes 0.000313 0.000309 0.000067 0.000146 0.000215 0.000159 0.000116 0.000111 0.000264 0.000194 0.000082 0.000132
Endoplasmic Reticulum 0.003682 0.002443 0.001967 0.004823 0.001791 0.002735 0.001554 0.002041 0.002726 0.002666 0.001842 0.003682
Endosome 0.027651 0.095815 0.005823 0.041539 0.026125 0.088549 0.009342 0.032460 0.026880 0.090259 0.006890 0.037817
Golgi 0.008842 0.031513 0.000229 0.004568 0.005474 0.014863 0.000408 0.005715 0.007141 0.018781 0.000283 0.005038
Lipid Particles 0.064073 0.063912 0.005129 0.026741 0.067082 0.076433 0.006409 0.011335 0.065593 0.073486 0.005517 0.020425
Mitochondria 0.014485 0.045162 0.001584 0.004797 0.007340 0.030102 0.000857 0.003947 0.010876 0.033647 0.001364 0.004449
Mitotic Spindle 0.001123 0.011423 0.008068 0.058978 0.004391 0.016748 0.003666 0.055461 0.002774 0.015495 0.006733 0.057536
None 0.004336 0.001638 0.007202 0.004454 0.005720 0.003471 0.007345 0.005331 0.005035 0.003039 0.007245 0.004813
Nuclear Periphery 0.001295 0.000748 0.004484 0.003653 0.001620 0.002008 0.002221 0.002564 0.001459 0.001711 0.003798 0.003207
Nuclear Periphery Foci 0.000757 0.001205 0.001923 0.011611 0.001695 0.001711 0.002425 0.004743 0.001231 0.001592 0.002075 0.008795
Nucleolus 0.002646 0.003406 0.002921 0.004022 0.003561 0.006100 0.004369 0.006644 0.003108 0.005466 0.003360 0.005097
Nucleus 0.111727 0.037752 0.445465 0.119002 0.146833 0.073297 0.426409 0.169295 0.129462 0.064931 0.439686 0.139622
Peroxisomes 0.017470 0.052878 0.001898 0.023509 0.012455 0.024024 0.004069 0.014254 0.014937 0.030815 0.002557 0.019715
Vacuole 0.039779 0.057270 0.037542 0.145787 0.027541 0.077657 0.052070 0.157338 0.033597 0.072858 0.041948 0.150523
Vacuole Periphery 0.001763 0.006495 0.000307 0.002800 0.001104 0.005314 0.000305 0.004208 0.001430 0.005592 0.000306 0.003377

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.93 -2.76 -6.28 -2.57 -6.12 -2.06 0.90 -2.63 -2.20 -2.76 -4.65 -0.46 -6.54 -4.84 -6.51
Bud Neck -1.56 4.00 -3.84 -1.21 -7.50 -9.29 1.99 -2.75 4.84 -4.00 -8.54 3.78 -5.11 3.33 -8.07
Bud Site -5.52 -5.16 -11.75 -8.03 -9.14 -6.44 -1.31 -6.81 -0.80 -5.53 -8.19 -4.64 -13.33 -6.35 -10.35
Cell Periphery -1.79 -3.00 -4.85 -0.56 -1.27 0.17 -3.60 -0.12 -0.22 3.03 -0.83 -4.69 -3.81 -2.30 1.23
Cytoplasm 20.11 -8.66 0.97 -18.00 8.99 19.63 -2.07 1.31 -13.75 2.89 25.22 -7.53 2.16 -19.77 8.70
Cytoplasmic Foci -5.87 56.10 34.50 30.03 -19.53 -2.23 34.31 31.99 35.82 -3.14 -2.39 66.90 45.91 44.41 -18.00
Eisosomes 0.17 16.71 11.73 6.67 -10.47 5.28 7.34 10.20 6.53 1.28 6.24 19.38 15.05 8.18 -7.54
Endoplasmic Reticulum 1.63 1.11 -2.82 -5.72 -7.55 -3.00 -1.96 -3.75 0.38 -1.36 0.18 -0.12 -4.48 -5.56 -6.95
Endosome -11.71 13.36 -2.63 10.38 -13.88 -18.19 6.98 -0.29 17.01 -6.48 -21.97 15.29 -2.37 19.65 -15.42
Golgi -9.05 14.69 7.78 11.48 -6.22 -8.25 10.40 1.96 7.90 -2.72 -11.05 18.03 6.34 14.18 -5.65
Lipid Particles 0.05 21.46 13.45 8.54 -10.95 -2.10 19.59 18.22 21.16 -2.71 -2.37 29.07 21.54 20.61 -11.17
Mitochondria -6.64 10.76 8.43 9.26 -5.85 -12.06 9.03 5.58 15.25 -4.39 -12.35 13.58 9.92 17.53 -6.97
Mitotic Spindle -4.64 -6.76 -13.64 -9.66 -10.97 -5.69 0.34 -8.29 -5.54 -8.48 -8.00 -4.61 -15.56 -10.52 -13.57
None 3.63 -2.31 0.70 -2.52 2.88 2.10 -0.70 1.15 -0.63 1.63 2.76 -1.90 1.44 -1.07 3.23
Nuclear Periphery 3.22 -11.47 -10.49 -12.24 2.64 -1.83 -4.62 -6.01 -5.03 -2.20 -1.74 -11.98 -11.81 -10.61 2.21
Nuclear Periphery Foci -2.42 -5.75 -9.42 -9.00 -6.70 -0.92 -3.63 -4.43 -4.14 -1.89 -2.89 -6.19 -10.25 -9.51 -6.76
Nucleolus -1.00 -3.04 -4.32 -2.42 -1.14 -4.71 -1.94 -3.95 -1.14 -1.60 -5.53 -3.25 -5.64 -0.94 -2.17
Nucleus 14.88 -46.76 -4.31 -16.71 40.17 15.21 -26.08 -3.25 -14.15 21.44 18.55 -52.23 -4.58 -19.40 44.62
Peroxisomes -8.91 14.76 -0.88 8.20 -11.28 -8.10 6.33 1.32 7.71 -3.65 -11.06 16.23 -0.43 9.31 -11.61
Vacuole -4.03 -5.47 -27.76 -20.62 -23.43 -16.56 -10.66 -26.30 -19.07 -18.17 -15.38 -11.64 -38.52 -27.52 -29.92
Vacuole Periphery -5.88 10.29 -0.18 4.85 -2.97 -9.85 5.20 -2.19 3.98 -3.58 -11.13 10.98 -1.63 6.48 -4.55
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Phosphatidylglycerol phospholipase C; regulates phosphatidylglycerol (PG) accumulation via a phospholipase C-type degradation mechanism; PG levels affect mitochondrial function; contains glycerophosphodiester phosphodiesterase motifs
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Pgc1

Pgc1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pgc1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available