Standard name
Human Ortholog
Description Protein required for the spindle pole body (SPB) duplication; localizes at the cytoplasmic side of the central plaque periphery of the SPB; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0.06 0.07 0.11 0.11 0.11 0.09 0.11 0.1 0.11 0.12 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0.05 0.05 0.09 0.09 0.05 0.12 0.08 0.1 0.09 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.05 0.05 0 0.07 0.07 0.05 0.05 0 0.06 0 0 0.1 0.11 0.14 0.09 0.11 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.29 0.29 0.15 0.12 0.13 0 0 0 0.06 0 0.05 0 0.21 0.34 0.41 0.26 0.27 0.32 0.17 0.2 0.16 0.16 0.13 0.14
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.07 0.05 0.09 0.09 0.13 0.29 0.31 0.31 0.32 0.37 0.35 0.31 0 0 0 0.08 0.07 0.06 0 0 0 0 0.05 0.06
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.33 0.23 0.13 0.13 0.12 0.18 0.17 0.22 0.22 0.17 0.21 0.21 0.2 0.14 0.18 0.21 0.22 0.21 0 0 0 0 0 0
Peroxisomes 0.1 0.08 0.06 0.07 0.07 0 0.05 0 0.08 0.05 0.09 0.06 0 0.09 0.12 0 0.05 0.07 0 0 0 0.07 0.06 0.06
SpindlePole 0.72 0.63 0.81 0.82 0.75 0.65 0.66 0.61 0.63 0.59 0.6 0.62 0.78 0.73 0.6 0.71 0.7 0.7 0.71 0.63 0.71 0.62 0.6 0.54
Vac/Vac Membrane 0.05 0.08 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0.09 0.06 0.05 0.06 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 6 4 2 3 14 5 2 2 0 2 3 4 3 0 3 3 1 0 4 4 2 5 10
Bud 7 9 34 33 70 71 100 66 75 68 107 152 3 1 3 12 8 4 1 9 4 12 10 22
Bud Neck 1 1 4 4 7 10 11 5 3 13 6 7 0 1 1 1 6 0 0 5 1 1 4 10
Bud Site 14 4 15 24 32 56 83 39 80 52 98 115 6 5 0 7 9 4 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
Cytoplasm 13 25 27 20 45 43 40 38 23 44 25 39 55 84 106 40 38 29 2 8 4 4 7 5
Endoplasmic Reticulum 0 1 1 2 0 1 1 0 1 0 0 0 3 0 1 9 11 11 0 1 2 0 3 9
Endosome 128 146 79 56 87 17 14 31 37 22 51 42 117 254 313 114 95 102 74 108 90 68 52 72
Golgi 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 3 1 2 4 2 2 2
Mitochondria 31 26 46 42 85 181 272 237 214 251 332 386 2 1 3 34 23 18 6 8 12 16 21 30
Nucleus 1 3 1 5 13 3 25 23 22 21 15 48 3 4 4 5 3 3 1 4 2 2 1 1
Nuclear Periphery 2 6 0 0 3 1 4 1 0 8 3 3 2 4 3 1 0 1 10 8 5 5 7 9
Nucleolus 144 117 68 58 79 113 148 164 146 115 194 263 114 106 137 92 76 66 1 8 2 0 1 1
Peroxisomes 42 39 32 33 47 21 43 29 55 34 86 80 20 71 95 11 16 22 10 12 14 29 24 33
SpindlePole 314 313 435 375 498 413 583 462 415 403 564 766 442 551 459 315 242 224 322 344 405 264 241 282
Vac/Vac Membrane 23 39 5 6 7 6 4 1 8 9 8 9 29 36 68 28 19 19 4 7 5 8 6 11
Unique Cell Count 436 500 536 457 664 631 883 756 660 685 944 1243 570 754 766 441 346 321 451 550 573 427 403 518
Labelled Cell Count 722 736 751 660 976 950 1333 1098 1081 1040 1491 1913 800 1122 1194 672 550 507 451 550 573 427 403 518


SpindlePole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.6 6.0 4.4 4.2 4.0 3.9 3.5 3.7 3.6 3.3 3.5 3.6 6.7 6.6 6.7 6.6 6.0 6.4 6.9 6.8 7.0
Std Deviation (1e-4) 0.8 1.1 0.9 1.2 1.2 1.2 1.2 1.2 1.0 1.0 0.8 1.0 1.2 1.6 1.4 1.1 1.1 1.2 0.9 1.4 1.8
Intensity Change (Log2) – – – -0.04 -0.13 -0.17 -0.34 -0.26 -0.28 -0.39 -0.33 -0.28 0.62 0.59 0.61 0.6 0.47 0.55 0.65 0.64 0.68

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 -5.4 -6.8 -6.4 -2.7 -2.7 -3.5
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 -2.1 -3.1 -4.7 -1.3 -0.2 -1.5
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.5 1.3 1.3 -0.4 0 -1.3 1.0 -2.4 -1.9 2.9 3.9 5.2 2.5 3.3 2.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 2.5 7.7 10.1 4.3 4.6 5.9
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 -6.7 -8.0 -7.6 -0.5 -1.0 -1.6
Nucleus 0 2.8 0 3.6 3.7 3.9 3.8 2.5 4.3 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 3.3 0.7 2.5 3.4 3.6 3.1
Peroxisomes 0 0 0 0 0 0 0 0 0 -1.9 2.3 3.8 -2.6 -0.9 0.5
SpindlePole 0 0 0 0 0 0 0 0 0 -1.5 -3.4 -8.1 -3.6 -3.9 -3.8
Vacuole 0.6 0.2 0 0 0 0.5 0.6 0 0 4.0 3.9 6.1 4.7 4.1 4.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.9796 1.4103 1.6516 1.3321 1.9851 1.4526 3.6342 3.8373 4.0522 3.6677 3.7939 3.7016 0.171 0.795 0.6982 0.7703 0.7197 0.489
Actin 0.0071 0.0026 0.0024 0.0016 0.006 0.0005 0.0113 0.0007 0.0117 0.0002 0.0012 0.0045 0.0014 0.0003 0.0002 0.0009 0.0004 0.0002
Bud 0.003 0.0047 0.0024 0.0031 0.0016 0.0009 0.0002 0.0001 0.0004 0 0.0001 0.0001 0 0 0 0 0.0001 0
Bud Neck 0.0021 0.0017 0.0068 0.0236 0.0013 0.0013 0.0008 0.0006 0.005 0.005 0.0002 0.001 0.0007 0.0002 0.0005 0.0003 0.0003 0.0003
Bud Periphery 0.0016 0.0014 0.0012 0.0014 0.0008 0.0003 0.0003 0.0001 0.0009 0 0.0002 0.0001 0 0 0 0 0 0
Bud Site 0.0058 0.0133 0.0055 0.0032 0.0014 0.0004 0.0013 0.0023 0.005 0.0003 0.0004 0.0004 0.0002 0.0003 0.0003 0.0001 0.0003 0.0001
Cell Periphery 0.0005 0.0001 0.0001 0.0003 0.0002 0.0001 0.0001 0.0001 0.0003 0 0 0 0 0 0 0 0 0
Cytoplasm 0.0058 0.0158 0.0043 0.0242 0.0079 0.0082 0.0033 0.0142 0.001 0.0005 0.0005 0.0031 0.0027 0.0025 0.0004 0.0009 0.0103 0.0014
Cytoplasmic Foci 0.1008 0.0486 0.0671 0.0722 0.1336 0.0332 0.0721 0.0492 0.0633 0.0596 0.0795 0.0265 0.0667 0.0737 0.1002 0.0687 0.1993 0.0525
Eisosomes 0.0002 0.0001 0 0.0001 0.0001 0 0.0002 0 0.0001 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0015 0.002 0.0005 0.001 0.0005 0.0002 0.0011 0.0016 0.0012 0.0001 0.0007 0.0004 0.0009 0.0005 0.0001 0.0002 0.0015 0.0003
Endosome 0.0486 0.0225 0.0121 0.0373 0.0689 0.005 0.0224 0.0218 0.0066 0.004 0.0128 0.005 0.007 0.0084 0.0058 0.0018 0.0173 0.0046
Golgi 0.0173 0.0036 0.0042 0.0306 0.0536 0.0015 0.0061 0.0028 0.0041 0.0023 0.0123 0.0015 0.0023 0.0022 0.0025 0.0011 0.005 0.0015
Lipid Particles 0.0725 0.0388 0.0586 0.0474 0.1252 0.0346 0.0594 0.0382 0.0535 0.0232 0.0591 0.0207 0.044 0.0492 0.0588 0.0159 0.2001 0.0228
Mitochondria 0.0299 0.0014 0.0088 0.0129 0.0825 0.0003 0.004 0.0017 0.0009 0 0.0044 0.0001 0.0002 0.0001 0 0 0.0001 0.0001
None 0.017 0.011 0.0018 0.0075 0.0086 0.002 0.0141 0.0076 0.0013 0.0002 0.0006 0.0007 0.0023 0.0004 0.0003 0.0006 0.0047 0.0012
Nuclear Periphery 0.0155 0.0123 0.0192 0.0182 0.0086 0.0073 0.0118 0.016 0.0152 0.0062 0.0187 0.0063 0.0168 0.0171 0.004 0.0183 0.0139 0.0074
Nucleolus 0.0197 0.0276 0.0251 0.005 0.0287 0.0089 0.0024 0.0108 0.0025 0.0024 0.0023 0.0016 0.0021 0.0077 0.0042 0.0011 0.002 0.0028
Nucleus 0.0211 0.0267 0.0137 0.0197 0.0096 0.0105 0.0057 0.0094 0.0018 0.0011 0.001 0.0012 0.0031 0.0192 0.0033 0.0069 0.0012 0.0062
Peroxisomes 0.025 0.0195 0.0215 0.0201 0.083 0.0089 0.0339 0.0099 0.0172 0.0049 0.009 0.0038 0.0056 0.0125 0.0176 0.0038 0.0122 0.0046
Punctate Nuclear 0.5958 0.7421 0.7418 0.6673 0.3712 0.8751 0.7482 0.8109 0.8067 0.8896 0.7955 0.9226 0.8435 0.8051 0.8015 0.8791 0.53 0.8938
Vacuole 0.0067 0.0036 0.0016 0.0018 0.0044 0.0005 0.0008 0.0015 0.0007 0.0001 0.0006 0.0002 0.0002 0.0004 0.0003 0 0.0007 0.0002
Vacuole Periphery 0.0025 0.0006 0.0016 0.0015 0.0024 0.0002 0.0006 0.0004 0.0003 0.0001 0.001 0.0001 0.0002 0.0003 0.0001 0.0001 0.0007 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.6228 6.8143 2.5283 10.1014 19.149 5.714 7.9665 8.4286 9.7096 15.4002
Translational Efficiency 1.1105 0.706 1.2918 0.5669 0.5074 1.503 0.8027 0.5312 0.6929 0.6557

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1770 2094 284 2153 1613 2491 1515 1623 3383 4585 1799 3776

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 667.64 800.13 902.63 904.39 752.45 772.48 800.13 941.04 708.08 785.11 816.31 920.14
Standard Deviation 90.77 115.93 106.20 121.77 85.25 304.49 120.01 132.64 97.83 238.11 123.71 127.85
Intensity Change Log 2 — 0.261164 0.435064 0.437875 — 0.037902 0.088639 0.322660 — 0.147179 0.261893 0.377975

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000168 0.000178 0.000409 0.000378 0.000156 0.000317 0.000185 0.000618 0.000162 0.000253 0.000220 0.000481
Bud Neck 0.001549 0.003144 0.002206 0.006986 0.001681 0.001771 0.001635 0.003161 0.001612 0.002398 0.001725 0.005342
Bud Site 0.001467 0.002343 0.001452 0.011425 0.000816 0.001813 0.001578 0.010252 0.001157 0.002055 0.001558 0.010921
Cell Periphery 0.000131 0.000102 0.000067 0.000078 0.000081 0.000106 0.000066 0.000062 0.000107 0.000104 0.000066 0.000071
Cytoplasm 0.012869 0.022095 0.001563 0.038627 0.012286 0.014847 0.011534 0.009541 0.012591 0.018157 0.009960 0.026125
Cytoplasmic Foci 0.133872 0.094668 0.005078 0.017134 0.080202 0.104559 0.008645 0.027781 0.108282 0.100041 0.008082 0.021711
Eisosomes 0.000053 0.000042 0.000036 0.000023 0.000060 0.000037 0.000023 0.000015 0.000056 0.000039 0.000025 0.000020
Endoplasmic Reticulum 0.001292 0.001536 0.004310 0.001523 0.001137 0.000950 0.001550 0.000946 0.001218 0.001218 0.001986 0.001275
Endosome 0.027983 0.023882 0.004877 0.015275 0.025195 0.037276 0.007051 0.022956 0.026654 0.031159 0.006708 0.018577
Golgi 0.011742 0.009336 0.000586 0.003792 0.008370 0.010849 0.000866 0.003282 0.010134 0.010158 0.000822 0.003573
Lipid Particles 0.223969 0.096815 0.008600 0.009231 0.168349 0.159287 0.008100 0.025281 0.197449 0.130756 0.008179 0.016130
Mitochondria 0.003714 0.001973 0.000413 0.004110 0.002575 0.003363 0.000485 0.002202 0.003171 0.002728 0.000473 0.003290
Mitotic Spindle 0.043352 0.180116 0.449741 0.625806 0.112925 0.183120 0.419983 0.609989 0.076524 0.181748 0.424681 0.619007
None 0.008945 0.005357 0.000558 0.003746 0.003454 0.006971 0.003014 0.000983 0.006327 0.006234 0.002626 0.002558
Nuclear Periphery 0.002161 0.002775 0.007286 0.007063 0.003145 0.003913 0.004088 0.004691 0.002630 0.003393 0.004593 0.006044
Nuclear Periphery Foci 0.473787 0.502353 0.462841 0.163549 0.510721 0.428087 0.487398 0.254031 0.491397 0.462005 0.483521 0.202440
Nucleolus 0.024100 0.025822 0.014117 0.027009 0.038359 0.015958 0.023900 0.004081 0.030898 0.020463 0.022356 0.017154
Nucleus 0.005106 0.011818 0.027012 0.043559 0.007680 0.007708 0.014912 0.004071 0.006334 0.009585 0.016822 0.026586
Peroxisomes 0.022601 0.013157 0.004415 0.005313 0.021292 0.016936 0.002273 0.006812 0.021977 0.015210 0.002611 0.005957
Vacuole 0.000908 0.002047 0.004277 0.013161 0.001080 0.001661 0.002596 0.007833 0.000990 0.001837 0.002862 0.010871
Vacuole Periphery 0.000234 0.000441 0.000156 0.002214 0.000437 0.000472 0.000120 0.001412 0.000331 0.000458 0.000125 0.001869

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.61 -4.20 -6.48 -6.73 0.98 -0.89 -4.92 -2.03 -1.56 -1.36 -1.00 -6.04 -3.94 -3.13 -1.97
Bud Neck -3.17 -4.59 -12.71 -10.23 -6.61 -0.02 -2.76 -3.96 -4.01 -2.41 -2.75 -4.75 -12.89 -11.33 -9.61
Bud Site -2.95 -2.90 -9.03 -8.42 -5.75 -3.08 -5.26 -6.35 -5.90 -4.97 -3.92 -5.42 -11.00 -10.26 -8.63
Cell Periphery 1.85 2.92 3.31 2.97 -0.05 -0.65 1.78 2.74 2.79 1.18 1.42 3.56 4.25 3.74 0.36
Cytoplasm -2.79 5.71 -11.58 -9.36 -14.92 -1.15 -1.89 -2.08 -1.16 -0.16 -2.69 -0.98 -11.20 -9.29 -9.04
Cytoplasmic Foci 6.57 22.92 22.93 19.18 -3.42 -3.16 18.90 13.16 18.67 -8.24 2.95 30.41 26.17 27.45 -8.25
Eisosomes 4.29 3.15 13.88 10.53 2.58 10.08 13.80 22.17 16.93 5.94 10.29 14.29 24.75 17.83 3.95
Endoplasmic Reticulum -0.66 -3.28 -2.47 -2.72 2.64 2.51 -3.48 0.46 -1.19 3.35 0.27 -4.19 -2.30 -3.57 2.97
Endosome 3.08 13.58 7.17 4.31 -6.71 -4.15 10.26 0.25 3.80 -7.86 -1.20 14.87 5.37 6.45 -8.68
Golgi 2.51 14.82 10.44 9.04 -3.32 -1.26 13.27 7.62 8.07 -1.85 1.30 19.01 12.89 11.97 -3.16
Lipid Particles 15.90 29.98 30.38 20.35 0.10 0.60 23.87 19.84 23.26 -7.68 11.29 38.26 36.03 31.48 -6.05
Mitochondria 1.48 2.79 -0.95 -3.62 -5.61 -0.83 2.74 -0.27 0.35 -1.74 0.58 3.54 -1.04 -1.80 -4.99
Mitotic Spindle -21.11 -16.95 -58.37 -36.00 -5.85 -9.62 -25.81 -42.10 -35.00 -12.80 -21.57 -35.04 -70.14 -50.36 -15.09
None 2.79 7.28 3.53 1.12 -7.96 -1.40 0.73 5.32 4.76 4.67 1.44 4.90 4.95 3.75 -0.37
Nuclear Periphery -1.08 -3.19 -7.49 -7.07 -0.76 -1.36 -1.91 -2.94 -2.09 -0.80 -1.86 -3.27 -7.76 -6.70 -2.68
Nuclear Periphery Foci 0.14 2.58 33.15 34.71 12.54 6.82 4.36 21.71 16.85 16.27 5.08 4.61 39.29 36.86 25.88
Nucleolus -0.70 2.00 -4.85 -4.29 -5.44 7.94 2.85 13.52 9.45 9.73 5.45 1.69 3.49 -1.56 1.12
Nucleus -4.26 -3.85 -15.13 -13.17 -2.25 0.72 -6.11 0.24 -0.32 5.70 -2.68 -7.62 -14.21 -12.82 -4.75
Peroxisomes 5.03 6.57 11.75 8.48 0.03 2.06 11.42 8.38 7.70 -3.08 4.85 15.82 14.33 11.63 -2.85
Vacuole -3.55 -2.20 -11.25 -10.56 -1.34 -1.23 -4.06 -6.74 -6.47 -4.48 -3.04 -4.39 -12.92 -12.25 -6.87
Vacuole Periphery -1.69 -1.04 -3.71 -3.37 -3.56 -0.30 1.59 -2.02 -1.95 -2.34 -1.19 1.45 -4.10 -3.81 -4.35
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein required for the spindle pole body (SPB) duplication; localizes at the cytoplasmic side of the central plaque periphery of the SPB; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p
Localization
Cell Percentages spindle pole (72%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Bbp1

Bbp1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Bbp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available