Standard name
Human Ortholog
Description Mu1-like medium subunit of the AP-1 complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; the AP-1 complex is the clathrin-associated protein complex
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.1 0.06 0.05 0 0 – 0 0 0 0 0 0.17 0.15 0.09 0.24 0.11 0.16 0.06 0.07 0.08 0.15 0.13 0.15
Bud 0 0.05 0 0.05 0 0 – 0.06 0.05 0.07 0.09 0.05 0.05 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Cytoplasm 0 0.08 0.06 0.08 0.08 0.06 – 0 0.05 0 0 0 0.07 0.15 0.14 0.24 0 0.2 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.24 0.05 0.05 0 0.06 – 0 0 0 0 0 0.12 0.1 0 0.12 0.06 0 0 0 0 0.06 0 0
Endosome 0.13 0 0.11 0.11 0.2 0.06 – 0.18 0.06 0 0.06 0 0.12 0.09 0.12 0.12 0.11 0.11 0.22 0.24 0.19 0.18 0.14 0.14
Golgi 0.33 0.24 0.58 0.32 0.41 0.11 – 0.05 0.05 0.05 0 0.05 0.45 0.47 0.25 0.29 0.61 0.52 0.56 0.38 0.62 0.31 0.45 0.44
Mitochondria 0.43 0.5 0.5 0.67 0.46 0.77 – 0.66 0.85 0.89 0.87 0.86 0.1 0.12 0 0.06 0.11 0.2 0 0.07 0 0.14 0.12 0.07
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.07 0 0 0 0 0 – 0.06 0.05 0.05 0 0.06 0 0 0 0 0.06 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0.08 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Vac/Vac Membrane 0.24 0.12 0.09 0.05 0.09 0.05 – 0.05 0 0 0 0 0.2 0.2 0.44 0.18 0.11 0.16 0.06 0.19 0 0.06 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 8 8 19 8 3 7 – 5 8 1 8 2 40 21 21 4 2 7 17 9 29 29 48 52
Bud 7 4 13 8 7 8 – 25 17 20 28 16 12 5 9 0 0 0 2 0 0 8 7 11
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0
Bud Site 0 0 0 0 0 1 – 6 3 8 7 11 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 0 1 1 0 2 – 1 2 4 3 2 2 1 0 1 0 0 0 0 0 0 0 0
Cytoplasm 7 6 20 13 14 17 – 19 20 6 11 7 17 21 32 4 0 9 1 1 0 1 1 3
Endoplasmic Reticulum 7 19 15 8 6 18 – 7 4 4 2 6 29 14 10 2 1 1 2 2 3 11 16 13
Endosome 28 1 33 17 37 18 – 79 21 11 20 14 28 13 28 2 2 5 58 31 66 34 50 47
Golgi 70 19 182 50 77 33 – 20 20 16 1 17 109 65 58 5 11 23 150 49 215 60 162 149
Mitochondria 91 39 156 103 86 235 – 289 320 263 279 272 24 16 5 1 2 9 10 9 15 25 45 25
Nucleus 0 0 1 1 0 2 – 0 2 1 0 0 1 0 3 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 3 – 2 1 5 3 3 0 0 0 0 0 0 1 0 2 1 2 3
Nucleolus 14 2 4 5 4 6 – 25 20 15 14 19 3 3 1 0 1 0 0 0 0 0 0 0
Peroxisomes 0 0 4 2 4 2 – 37 3 2 7 2 0 0 0 0 0 0 2 0 5 5 8 8
SpindlePole 2 0 0 0 4 3 – 18 7 5 9 7 4 4 4 0 0 2 1 0 1 0 1 1
Vac/Vac Membrane 50 9 28 8 16 15 – 23 4 13 11 13 47 27 101 3 2 7 16 24 8 10 15 15
Unique Cell Count 211 78 314 154 186 305 438 375 296 320 316 240 137 231 17 18 44 268 132 350 191 363 340
Labelled Cell Count 285 107 476 224 258 370 556 452 374 403 391 316 190 272 22 21 63 268 132 350 191 363 340


Late Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.5 9.7 10.0 9.4 9.3 7.6 – 7.7 7.2 7.0 6.6 7.1 9.9 10.1 10.3 8.7 9.1 11.0 9.8 10.5 10.7
Std Deviation (1e-4) 1.6 1.5 1.4 1.4 1.6 1.4 – 1.6 1.5 1.6 1.6 1.5 1.2 1.4 2.0 1.7 1.4 2.5 1.7 1.5 1.7
Intensity Change (Log2) – – – -0.1 -0.11 -0.4 – -0.39 -0.48 -0.52 -0.61 -0.49 -0.02 0.01 0.04 -0.2 -0.14 0.13 -0.03 0.07 0.1

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.4 -2.3 -2.3 – -3.8 -2.6 -4.0 -2.2 -3.8 4.0 3.2 1.3 0 0 0
Bud 0.5 -0.2 -1.0 – 1.0 0.3 1.4 2.4 0.6 0.5 -0.2 -0.1 0 0 0
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 3.3 0 0 0 0 0 0
Cell Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.8 0.5 -0.4 – -1.2 -0.6 -2.7 -1.7 -2.6 0.3 3.0 2.9 0 0 0
Endoplasmic Reticulum 0.2 -0.8 0.6 – -2.6 -3.0 -2.4 -3.2 -2.0 3.2 2.2 -0.2 0 0 0
Endosome 0.2 2.9 -2.1 – 2.9 -2.4 -3.2 -1.9 -2.9 0.4 -0.3 0.6 0 0 0
Golgi -5.2 -3.6 -12.3 – -16.3 -15.1 -13.9 -16.0 -14.2 -2.9 -2.1 -7.6 -2.3 0.3 -0.7
Mitochondria 3.5 -0.7 7.1 – 4.5 10.1 10.4 10.2 9.8 -9.9 -7.6 -12.0 -3.5 -3.2 -3.6
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 – 3.1 2.9 2.7 2.4 3.2 0 0 0 0 0 0
Peroxisomes 0 0 0 – 4.3 0 0 0.9 0 0 0 0 0 0 0
SpindlePole 0 0 0 – 3.6 0 0 0 0 0 0 0 0 0 0
Vacuole -1.4 -0.1 -2.0 – -2.0 -4.9 -2.2 -2.9 -2.4 3.6 3.2 9.4 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.4694 7.6038 7.3288 6.8251 6.8832 7.4848 8.5565 9.558 8.8958 8.965 8.221 9.1184 10.1868 10.3889 9.9837 10.2498 9.2484 10.1868
Actin 0.0449 0.0128 0.0099 0.0013 0.0094 0.004 0.0174 0.0108 0.0222 0.0054 0.0038 0.02 0.0295 0.0137 0.0238 0.0054 0.0034 0.0065
Bud 0.0004 0.0004 0.0028 0.0026 0.0002 0.0002 0.0003 0.0005 0.0025 0.0004 0.0004 0.0003 0.0008 0.0006 0.0011 0.0009 0.0002 0.0004
Bud Neck 0.0031 0.0005 0.001 0.0004 0.0006 0.0006 0.0005 0.0005 0.0007 0.0004 0.0003 0.0012 0.0006 0.0008 0.0011 0.0004 0.0003 0.0003
Bud Periphery 0.0004 0.0003 0.0024 0.0034 0.0003 0.0002 0.0003 0.0002 0.0024 0.0003 0.0004 0.0003 0.001 0.0005 0.001 0.001 0.0002 0.0008
Bud Site 0.0036 0.0015 0.0032 0.0009 0.0003 0.0004 0.0008 0.0019 0.0049 0.0004 0.0004 0.0008 0.0022 0.0027 0.003 0.0005 0.0002 0.0003
Cell Periphery 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0 0.0001
Cytoplasm 0.0122 0.0086 0.0094 0.0068 0.0024 0.0071 0.0027 0.0066 0.0037 0.0024 0.002 0.0021 0.0034 0.0214 0.0037 0.0025 0.0029 0.0016
Cytoplasmic Foci 0.1081 0.1351 0.1011 0.0592 0.0606 0.0803 0.0978 0.1119 0.0864 0.0749 0.0794 0.0675 0.0801 0.1208 0.0842 0.0606 0.075 0.0612
Eisosomes 0.0005 0 0.0001 0 0.0001 0 0.0001 0 0.0001 0 0 0.0002 0.0002 0 0.0001 0 0 0
Endoplasmic Reticulum 0.0077 0.0012 0.0029 0.0016 0.0024 0.0017 0.0016 0.0007 0.0007 0.0004 0.0005 0.0009 0.0008 0.0005 0.0008 0.0006 0.0009 0.0008
Endosome 0.3044 0.4027 0.3171 0.4654 0.3449 0.2877 0.2704 0.3958 0.2859 0.3356 0.319 0.273 0.3484 0.3392 0.3147 0.3931 0.3834 0.2448
Golgi 0.4149 0.3883 0.4942 0.392 0.5058 0.5837 0.5348 0.4492 0.5304 0.5472 0.5588 0.5895 0.4904 0.4562 0.5207 0.5068 0.5061 0.6484
Lipid Particles 0.0205 0.0086 0.0084 0.0039 0.0118 0.0043 0.0102 0.0026 0.0049 0.0018 0.0056 0.0047 0.005 0.0033 0.0042 0.0014 0.0027 0.0053
Mitochondria 0.0182 0.0096 0.0129 0.015 0.0116 0.0162 0.0328 0.0098 0.0284 0.0181 0.0193 0.0238 0.0265 0.0254 0.017 0.0145 0.006 0.0131
None 0.0116 0.0005 0.0006 0.0001 0.0017 0.0002 0.0001 0.0001 0.0002 0 0.0001 0.0001 0.0002 0.0001 0.0001 0 0.0001 0.0001
Nuclear Periphery 0.011 0.0005 0.0062 0.0008 0.0211 0.0005 0.0026 0.0001 0.0004 0.0001 0.0001 0.0011 0.0003 0.0001 0.0002 0.0002 0.0005 0.0008
Nucleolus 0.0007 0.0003 0.0005 0.0001 0.0004 0 0.0001 0 0.0003 0 0 0.0001 0 0.0001 0.0001 0 0 0
Nucleus 0.003 0.0004 0.0048 0.0003 0.0034 0.0002 0.0004 0.0001 0.0002 0 0.0001 0.0002 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001
Peroxisomes 0.0239 0.0134 0.0124 0.0021 0.0033 0.0056 0.0218 0.0046 0.0158 0.0092 0.0051 0.0062 0.0035 0.007 0.0146 0.002 0.0018 0.0103
Punctate Nuclear 0.0043 0.0029 0.0018 0.0001 0.0081 0.0002 0.0003 0.0001 0.0004 0.0001 0.0001 0.0002 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001
Vacuole 0.0035 0.0079 0.0046 0.0306 0.0065 0.0038 0.0026 0.0023 0.0062 0.0012 0.0019 0.004 0.0035 0.0046 0.0059 0.0049 0.0082 0.002
Vacuole Periphery 0.0031 0.0044 0.0035 0.0132 0.0049 0.003 0.0025 0.0024 0.0033 0.0021 0.0025 0.0037 0.0032 0.0025 0.0033 0.0048 0.0079 0.003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 20.09 14.5055 19.9898 25.1993 15.5284 16.9898 26.8886 22.3904 24.3594 26.0037
Translational Efficiency 0.848 1.2531 0.8297 0.8311 0.9083 0.9979 0.8395 0.9214 0.8231 0.7501

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
92 976 510 829 2229 1553 2561 1820 2321 2529 3071 2649

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1243.92 1140.51 1299.37 1231.91 919.98 1044.37 1190.23 1246.05 932.82 1081.47 1208.35 1241.62
Standard Deviation 162.37 172.57 165.71 171.04 120.81 144.18 162.20 154.62 138.04 162.63 167.78 160.08
Intensity Change Log 2 — -0.125215 0.062919 -0.013997 — 0.182959 0.371566 0.437688 — 0.013920 0.202280 0.195519

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003705 0.004423 0.002606 0.002585 0.002109 0.001305 0.001408 0.002080 0.002173 0.002508 0.001607 0.002238
Bud Neck 0.001720 0.000430 0.001528 0.001301 0.000521 0.000540 0.000202 0.000439 0.000568 0.000497 0.000422 0.000708
Bud Site 0.046225 0.013006 0.012317 0.025625 0.013195 0.007929 0.006431 0.016818 0.014505 0.009888 0.007409 0.019574
Cell Periphery 0.000270 0.000216 0.000199 0.000672 0.000159 0.000153 0.000077 0.000226 0.000164 0.000178 0.000097 0.000366
Cytoplasm 0.012394 0.003598 0.002726 0.012632 0.005095 0.004541 0.004232 0.010916 0.005384 0.004177 0.003982 0.011453
Cytoplasmic Foci 0.121022 0.171529 0.128089 0.100545 0.136463 0.169569 0.088513 0.080912 0.135851 0.170325 0.095086 0.087056
Eisosomes 0.000030 0.000045 0.000025 0.000027 0.000065 0.000035 0.000017 0.000020 0.000064 0.000039 0.000018 0.000022
Endoplasmic Reticulum 0.001936 0.000826 0.003492 0.001355 0.001229 0.000948 0.000290 0.000700 0.001257 0.000901 0.000822 0.000905
Endosome 0.211339 0.146220 0.146075 0.148324 0.164745 0.207850 0.129544 0.125571 0.166592 0.184065 0.132290 0.132692
Golgi 0.180598 0.602983 0.475080 0.340452 0.545272 0.484395 0.618179 0.474266 0.530817 0.530161 0.594415 0.432390
Lipid Particles 0.000996 0.000932 0.002923 0.001308 0.001286 0.003462 0.000999 0.000562 0.001274 0.002485 0.001318 0.000795
Mitochondria 0.011340 0.017387 0.001828 0.006293 0.079818 0.039789 0.012412 0.008591 0.077104 0.031144 0.010654 0.007872
Mitotic Spindle 0.013876 0.005108 0.019698 0.014386 0.003237 0.008764 0.007199 0.006233 0.003659 0.007353 0.009275 0.008784
None 0.000021 0.000266 0.000040 0.000235 0.000070 0.000194 0.000035 0.000054 0.000068 0.000222 0.000036 0.000111
Nuclear Periphery 0.000188 0.000044 0.000707 0.000606 0.000046 0.000137 0.000105 0.000115 0.000051 0.000101 0.000205 0.000269
Nuclear Periphery Foci 0.000872 0.000229 0.004759 0.002325 0.000174 0.000517 0.000603 0.000631 0.000201 0.000406 0.001293 0.001161
Nucleolus 0.000033 0.000107 0.000319 0.000120 0.000025 0.000087 0.000011 0.000039 0.000026 0.000095 0.000062 0.000064
Nucleus 0.000172 0.000058 0.000303 0.000096 0.000041 0.000437 0.000020 0.000045 0.000046 0.000291 0.000067 0.000061
Peroxisomes 0.003465 0.002081 0.001872 0.001967 0.002778 0.003497 0.000816 0.001128 0.002805 0.002951 0.000992 0.001391
Vacuole 0.291707 0.013532 0.121761 0.226855 0.016309 0.029414 0.068718 0.148904 0.027225 0.023285 0.077527 0.173299
Vacuole Periphery 0.098094 0.016979 0.073654 0.112292 0.027363 0.036438 0.060189 0.121748 0.030167 0.028928 0.062425 0.118789

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.28 0.42 0.44 1.39 0.02 1.50 1.10 -0.07 -1.28 -0.99 -0.51 0.94 -0.20 0.32 -1.14
Bud Neck 3.74 0.53 0.98 -4.36 0.59 -0.27 4.89 0.88 1.08 -4.73 0.89 1.88 -1.82 -2.72 -3.67
Bud Site 2.29 2.29 1.35 -3.93 -3.68 3.70 5.12 -2.24 -5.96 -7.44 2.97 4.93 -3.12 -6.53 -8.89
Cell Periphery 0.57 0.85 -1.27 -1.45 -1.52 0.12 5.68 -2.68 -1.69 -6.36 -0.46 4.52 -2.06 -1.84 -2.75
Cytoplasm 2.51 2.71 -0.14 -5.48 -5.79 0.69 1.30 -5.27 -5.30 -5.88 2.04 2.36 -6.41 -7.61 -7.83
Cytoplasmic Foci -3.96 -0.54 1.56 12.29 3.81 -8.24 17.13 18.40 22.27 2.78 -10.24 14.62 16.88 25.67 3.03
Eisosomes -1.44 0.44 0.30 3.39 -0.26 8.01 13.29 12.65 6.25 -1.51 6.96 13.10 11.68 6.96 -1.80
Endoplasmic Reticulum 1.33 -1.10 0.66 -1.29 1.80 0.62 2.47 1.35 0.94 -4.47 0.89 1.06 0.90 -0.02 -0.36
Endosome 3.53 3.46 3.42 -0.25 -0.24 -8.07 8.89 9.26 15.81 1.05 -3.96 8.99 8.63 12.82 -0.07
Golgi -17.23 -10.89 -6.18 20.77 8.00 7.25 -9.67 8.10 1.15 16.18 0.10 -8.53 12.44 12.60 20.76
Lipid Particles 0.34 -2.42 -0.48 -1.29 2.38 -2.80 0.66 2.19 3.91 1.28 -2.29 -0.12 1.47 3.56 1.68
Mitochondria -0.64 0.98 0.52 4.91 -3.55 9.99 21.04 22.32 11.53 3.12 13.24 21.55 22.55 12.33 2.75
Mitotic Spindle 1.01 -0.70 -0.25 -4.01 0.95 -4.40 -4.36 -3.23 1.68 0.84 -3.80 -5.43 -5.02 -1.57 0.08
None -1.06 -2.41 -1.15 0.12 -1.05 -1.23 7.41 2.71 1.37 -4.82 -1.43 7.09 -0.74 0.93 -1.28
Nuclear Periphery 2.39 -2.06 -1.60 -2.19 0.20 -3.68 -4.08 -4.15 0.76 -0.48 -2.83 -3.64 -2.66 -2.05 -0.76
Nuclear Periphery Foci 2.47 -2.71 -2.24 -3.33 1.34 -2.62 -3.17 -3.01 -0.56 -0.13 -2.20 -4.22 -4.21 -3.27 0.09
Nucleolus -0.73 -1.00 -1.40 -0.40 0.55 -2.75 2.35 -1.18 1.70 -2.21 -1.74 -0.77 -1.80 0.33 -0.30
Nucleus 1.42 -0.34 1.06 -1.20 0.87 -2.35 3.32 -0.84 2.31 -5.21 -2.32 -0.52 -1.89 2.16 0.10
Peroxisomes 1.71 1.78 1.79 0.18 -0.22 -1.28 4.79 4.09 4.65 -1.07 -0.35 4.66 3.73 4.41 -1.59
Vacuole 9.66 5.74 2.23 -24.73 -9.09 -7.06 -20.43 -29.64 -25.47 -15.91 1.93 -16.67 -32.66 -35.37 -20.06
Vacuole Periphery 5.90 1.60 -1.00 -17.48 -4.80 -3.90 -13.50 -24.13 -20.23 -14.38 0.64 -13.40 -26.82 -26.96 -15.41
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mu1-like medium subunit of the AP-1 complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; the AP-1 complex is the clathrin-associated protein complex
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Apm1

Apm1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Apm1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available