Standard name
Human Ortholog
Description Cyclin associated with protein kinase Kin28p; Kin28p is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters; human homolog CCNH allows growth of yeast ccl1 temperature-sensitive mutant at restrictive temperature
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.05 0 0 0 0 0 0 0 0 0.1 0.13 0.14 0.09 0.06 0.05 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.18 0.09 0 0.09 0.13 0.29 0.25 0.25 0.29 0.4 0.42 0.37 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.91 0.95 0.91 0.88 0.86 0.83 0.82 0.82 0.76 0.74 0.69 0.7 0.89 0.85 0.83 0.86 0.89 0.89 0.87 0.88 0.82 0.83 0.84 0.73
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.21 0.19 0.11 0.08 0.11 0.14 0.24 0.24 0.27 0.26 0.29 0.29 0 0 0 0.05 0 0.06 0.06 0.06 0.1 0.06 0.06 0.1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.09
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0
Bud 0 0 1 0 2 1 3 3 5 3 7 4 0 0 0 0 2 1 0 3 8 1 1 4
Bud Neck 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 1 0 0 1 3 11 13 19 16 15 9 24 0 0 1 0 1 0 – – – – – –
Cell Periphery 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 3 3 9 16 12 9 10 10 5 6 7 3 45 56 64 28 16 14 0 0 1 1 1 4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 2 2 0 0 0 0 0 0
Endosome 0 0 0 1 1 1 0 0 0 0 0 0 1 0 3 0 3 2 2 0 1 4 3 5
Golgi 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 2 1 0 1 1 3 2 0 1
Mitochondria 41 16 14 28 44 161 118 118 147 188 222 255 2 0 4 11 5 6 2 0 0 1 1 8
Nucleus 207 178 348 276 298 459 388 388 378 351 368 482 412 359 380 281 255 232 205 174 321 294 285 299
Nuclear Periphery 0 0 5 1 0 5 9 8 5 4 5 11 2 2 3 2 6 1 0 0 1 3 0 2
Nucleolus 49 35 44 24 38 79 112 112 135 125 152 197 16 5 13 15 11 15 14 11 38 21 21 41
Peroxisomes 0 0 1 2 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0
SpindlePole 0 0 1 1 0 0 1 1 0 1 1 0 6 3 8 0 6 1 1 0 2 2 3 3
Vac/Vac Membrane 1 1 3 1 0 1 3 2 3 2 3 3 4 2 6 7 5 6 4 4 11 15 18 34
Unique Cell Count 228 188 383 315 345 550 476 476 500 474 533 689 465 424 458 326 288 262 235 198 392 354 340 410
Labelled Cell Count 302 233 429 351 399 727 657 661 694 695 775 981 490 427 483 352 313 280 235 198 392 354 340 410


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.7 7.0 6.2 5.8 5.6 4.9 4.9 4.9 4.9 4.7 4.2 4.6 7.6 7.2 6.8 8.8 8.6 8.3 7.6 7.5 8.1
Std Deviation (1e-4) 1.2 1.2 1.4 1.7 1.6 1.3 1.2 1.2 1.2 1.1 1.3 1.1 1.6 1.6 1.6 2.4 1.9 2.0 1.3 1.5 1.4
Intensity Change (Log2) – – – -0.09 -0.15 -0.35 -0.35 -0.35 -0.34 -0.41 -0.55 -0.44 0.3 0.22 0.13 0.51 0.47 0.42 0.29 0.27 0.39

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 3.5 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.9 0.9 -0.8 -0.2 -0.2 -1.6 -1.2 -1.2 0 4.3 5.7 6.0 3.7 2.2 2.0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.9 4.5 0 0 0 9.8 0 0 0 -3.4 -4.0 -2.8 -0.2 -1.5 -1.0
Nucleus -1.4 -1.9 -3.3 -3.9 -3.9 -5.9 -6.3 -7.9 -7.8 -1.1 -2.7 -3.3 -2.0 -1.0 -1.0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus -1.7 -0.2 0 0 0 5.7 0 0 0 -4.5 -6.1 -5.0 -3.3 -3.6 -2.5
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.9709 3.6593 2.9417 3.2124 2.5899 3.2329 3.5041 3.4695 3.1018 3.3463 2.839 3.2178 3.0083 3.1163 2.6797 3.0998 2.8754 2.6616
Actin 0.0284 0 0.0003 0.0001 0 0.0009 0.0162 0.0071 0.0146 0.0118 0.0011 0.0036 0.0123 0 0.0184 0.0008 0.0366 0
Bud 0.0002 0 0 0 0 0 0.0005 0 0.0003 0.0004 0.0002 0.0001 0.0007 0 0.0004 0.0001 0.0011 0
Bud Neck 0.0005 0 0 0.0002 0.0002 0.0007 0.0014 0.0001 0.0032 0.0006 0.0008 0.0007 0.0012 0 0.0012 0.0003 0.0032 0.0007
Bud Periphery 0.0003 0 0 0 0 0.0001 0.0018 0 0.0008 0.0006 0.0003 0.0002 0.0021 0 0.001 0 0.0037 0
Bud Site 0.0006 0 0 0 0 0.0001 0.0019 0.0003 0.0009 0.0017 0.0006 0.0002 0.0011 0 0.0016 0.0003 0.004 0
Cell Periphery 0.0001 0 0 0 0 0 0.0005 0 0.0002 0.0001 0.0001 0 0.0004 0 0.0003 0.0001 0.0007 0
Cytoplasm 0.005 0 0 0.0004 0 0.003 0.0019 0 0.0009 0.0027 0.0014 0.0007 0.0057 0 0.0006 0.0207 0.0011 0.0001
Cytoplasmic Foci 0.0073 0 0.0004 0.0016 0 0.0009 0.0071 0.0001 0.0064 0.0029 0.0063 0.0005 0.0059 0 0.0013 0.0009 0.0164 0
Eisosomes 0.0006 0 0 0 0 0 0.0004 0 0.0002 0.0001 0 0 0.0001 0 0.0001 0 0.0007 0
Endoplasmic Reticulum 0.0029 0 0 0.0002 0 0.0002 0.0015 0 0.0006 0.003 0.0009 0.0014 0.002 0 0.0011 0.0051 0.0029 0
Endosome 0.0097 0 0.0003 0.0017 0 0.002 0.0085 0 0.0032 0.0057 0.0081 0.0026 0.0102 0 0.0016 0.0017 0.0217 0.0001
Golgi 0.0035 0 0.0006 0.0002 0 0.0009 0.003 0.0001 0.0016 0.0012 0.0014 0.0011 0.0037 0 0.0011 0.0001 0.0074 0
Lipid Particles 0.0089 0 0.0043 0.001 0 0.0024 0.0136 0 0.0123 0.0011 0.0188 0.0019 0.0027 0 0.0071 0.0003 0.0203 0
Mitochondria 0.0028 0 0.0007 0.0001 0 0.0006 0.0208 0.0001 0.0079 0.0011 0.0037 0.0013 0.008 0.0001 0.0086 0.0003 0.0387 0.0002
None 0.0051 0 0 0.0003 0 0.0001 0.0104 0 0.0006 0.0015 0.001 0.0003 0.0032 0 0.0002 0.0009 0.0016 0
Nuclear Periphery 0.0108 0.0003 0.0003 0.0212 0.0005 0.0016 0.0266 0.0005 0.0046 0.0161 0.0092 0.0111 0.0068 0.0005 0.003 0.0091 0.0292 0.0013
Nucleolus 0.0198 0.0118 0.0077 0.0118 0.085 0.0605 0.0228 0.0125 0.0168 0.0068 0.0642 0.0399 0.0158 0.0085 0.0141 0.0054 0.0933 0.0348
Nucleus 0.8698 0.9877 0.9818 0.9039 0.9097 0.9203 0.834 0.978 0.9101 0.9325 0.8617 0.9271 0.908 0.9908 0.9341 0.9488 0.6927 0.961
Peroxisomes 0.0149 0 0.0031 0.0001 0 0.0004 0.0056 0.0001 0.0093 0.0004 0.0031 0.0004 0.0005 0 0.0011 0 0.0032 0
Punctate Nuclear 0.007 0.0002 0.0002 0.0567 0.0045 0.0049 0.0143 0.0009 0.0029 0.0087 0.0149 0.0062 0.0034 0.0001 0.0013 0.0041 0.0049 0.0014
Vacuole 0.0009 0 0 0.0002 0 0.0002 0.0038 0 0.002 0.0006 0.0012 0.0004 0.0042 0 0.0011 0.0007 0.0081 0.0001
Vacuole Periphery 0.0007 0 0 0.0003 0 0.0001 0.0033 0 0.0008 0.0006 0.0009 0.0004 0.0019 0 0.0007 0.0002 0.0088 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 17.2699 10.8485 9.9077 17.067 16.9446 3.732 17.719 19.0776 19.6195 17.2712
Translational Efficiency 1.1068 1.8609 1.6265 1.1088 0.9317 4.5723 1.0381 1.0523 0.9965 1.1392

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1820 409 2951 1375 1665 512 176 950 3485 921 3127 2325

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 827.84 975.71 1033.64 992.93 778.92 908.26 1045.09 1126.37 804.47 938.21 1034.28 1047.45
Standard Deviation 107.59 137.41 142.16 160.14 114.18 134.78 136.89 172.69 113.45 140.02 141.89 177.92
Intensity Change Log 2 — 0.237100 0.320310 0.262340 — 0.221630 0.424080 0.532134 — 0.229622 0.371548 0.399433

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000437 0.000518 0.000550 0.001063 0.000397 0.000489 0.001064 0.001094 0.000418 0.000502 0.000579 0.001076
Bud Neck 0.005701 0.008128 0.031456 0.024467 0.004827 0.008466 0.006990 0.025027 0.005283 0.008316 0.030079 0.024696
Bud Site 0.000414 0.000491 0.001168 0.002884 0.000763 0.000624 0.000689 0.004864 0.000580 0.000565 0.001141 0.003693
Cell Periphery 0.000038 0.000020 0.000045 0.000144 0.000158 0.000084 0.000025 0.000111 0.000096 0.000055 0.000044 0.000131
Cytoplasm 0.000441 0.000100 0.000196 0.001993 0.001538 0.001508 0.000125 0.001882 0.000965 0.000883 0.000192 0.001948
Cytoplasmic Foci 0.000319 0.001372 0.000004 0.001456 0.000129 0.000671 0.000019 0.001397 0.000228 0.000982 0.000005 0.001432
Eisosomes 0.000021 0.000029 0.000043 0.000037 0.000021 0.000027 0.000043 0.000033 0.000021 0.000028 0.000043 0.000035
Endoplasmic Reticulum 0.002661 0.002442 0.002172 0.003550 0.003057 0.003166 0.003187 0.003130 0.002850 0.002845 0.002229 0.003379
Endosome 0.000200 0.000618 0.000076 0.002276 0.000277 0.000134 0.000061 0.002668 0.000237 0.000349 0.000075 0.002437
Golgi 0.000174 0.000477 0.000069 0.001229 0.000115 0.000102 0.000104 0.004467 0.000145 0.000269 0.000071 0.002552
Lipid Particles 0.000342 0.000124 0.000015 0.000510 0.000130 0.000355 0.000053 0.000147 0.000241 0.000253 0.000018 0.000361
Mitochondria 0.001617 0.002222 0.001282 0.003854 0.001065 0.000780 0.001068 0.007885 0.001353 0.001420 0.001270 0.005501
Mitotic Spindle 0.002901 0.003221 0.000692 0.014301 0.001987 0.006027 0.000323 0.016418 0.002464 0.004781 0.000671 0.015166
None 0.001591 0.000927 0.000846 0.004478 0.003498 0.002596 0.001053 0.002205 0.002502 0.001855 0.000858 0.003549
Nuclear Periphery 0.000474 0.000084 0.000222 0.001684 0.000275 0.000135 0.000127 0.002204 0.000379 0.000112 0.000217 0.001896
Nuclear Periphery Foci 0.000718 0.000612 0.000023 0.000821 0.000710 0.000198 0.000071 0.001450 0.000714 0.000382 0.000026 0.001078
Nucleolus 0.042515 0.033557 0.023550 0.024238 0.037750 0.031004 0.036167 0.016441 0.040238 0.032138 0.024261 0.021053
Nucleus 0.938223 0.943516 0.937050 0.901618 0.942331 0.942783 0.947128 0.894149 0.940186 0.943109 0.937617 0.898566
Peroxisomes 0.000424 0.000698 0.000181 0.000572 0.000373 0.000423 0.001069 0.000415 0.000399 0.000545 0.000231 0.000508
Vacuole 0.000359 0.000308 0.000244 0.004475 0.000363 0.000319 0.000523 0.008118 0.000361 0.000314 0.000259 0.005964
Vacuole Periphery 0.000430 0.000537 0.000115 0.004349 0.000236 0.000109 0.000111 0.005895 0.000337 0.000299 0.000115 0.004981

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.49 -1.43 -4.63 -12.12 -10.89 -1.82 -10.06 -9.75 -7.99 -1.83 -1.05 -3.21 -8.98 -13.14 -11.16
Bud Neck -2.73 -25.61 -15.26 -12.13 4.37 -2.96 -3.46 -13.61 -9.82 -10.22 -3.82 -26.85 -20.54 -15.02 3.32
Bud Site -0.72 -10.14 -8.47 -8.38 -5.04 0.56 -0.38 -3.96 -4.13 -3.94 0.11 -6.94 -6.92 -7.05 -5.13
Cell Periphery 3.37 -1.09 -5.22 -6.61 -4.86 0.79 1.53 0.68 -0.33 -3.32 0.88 1.24 -0.44 -2.75 -5.22
Cytoplasm 3.69 2.28 -5.80 -7.76 -7.17 -0.10 3.58 -0.29 -0.06 -3.73 0.03 3.81 -2.83 -1.49 -7.17
Cytoplasmic Foci -0.82 2.31 -1.72 0.34 -2.92 -1.13 3.86 -2.78 -0.22 -3.23 -1.25 3.13 -2.98 0.17 -4.22
Eisosomes -4.12 -18.59 -11.80 -4.84 4.30 -2.48 -8.31 -9.05 -4.27 2.24 -4.31 -20.64 -14.72 -6.30 4.99
Endoplasmic Reticulum 0.98 1.91 -3.39 -4.14 -5.56 -0.51 -0.22 -1.13 -0.39 -0.69 -0.05 3.63 -3.35 -2.82 -6.86
Endosome -0.87 3.35 -3.29 -1.47 -3.59 1.91 3.10 -3.36 -3.72 -3.89 -0.50 4.08 -4.63 -3.52 -5.19
Golgi -0.81 1.66 -2.45 -0.84 -2.85 0.29 -0.03 -2.25 -2.26 -2.25 -0.71 2.00 -2.91 -2.57 -3.03
Lipid Particles 1.44 2.31 -0.01 -0.96 -1.45 -0.96 3.48 -0.13 0.94 -3.09 -0.10 3.01 -0.12 -0.01 -1.80
Mitochondria -0.35 0.36 -3.60 -0.80 -5.70 1.23 -0.51 -4.39 -4.65 -4.35 -0.07 -0.47 -5.77 -3.71 -5.97
Mitotic Spindle -0.12 1.66 -4.37 -3.23 -5.39 -1.22 1.23 -4.25 -2.03 -4.75 -1.07 1.73 -6.14 -3.43 -7.06
None 2.91 3.10 -3.87 -5.16 -5.17 0.84 6.00 3.06 0.45 -3.96 1.14 7.32 -1.90 -2.24 -6.29
Nuclear Periphery 2.47 1.20 -3.36 -5.40 -4.64 2.90 2.74 -3.20 -3.47 -3.45 3.11 1.21 -4.70 -5.90 -5.30
Nuclear Periphery Foci 0.15 1.78 0.17 -0.05 -3.39 1.87 2.31 -0.77 -2.13 -2.41 1.09 2.93 -0.39 -1.55 -3.84
Nucleolus 2.81 6.58 7.11 2.59 1.90 1.94 -0.30 6.82 3.00 3.07 3.42 6.47 9.58 3.71 3.56
Nucleus -0.99 3.42 6.06 5.46 4.32 -0.01 0.11 6.66 5.51 4.99 -0.69 4.71 9.04 7.68 6.29
Peroxisomes -1.25 1.56 -0.37 1.17 -3.58 -0.59 -4.81 -2.03 -1.04 3.84 -1.27 1.76 -1.11 0.43 -4.67
Vacuole 0.44 0.45 -4.60 -4.69 -4.72 0.19 -1.83 -4.37 -4.38 -4.22 0.42 0.50 -6.25 -6.30 -6.33
Vacuole Periphery -0.23 1.98 -2.92 -2.57 -3.36 2.00 1.89 -3.10 -3.22 -3.21 0.23 2.48 -4.28 -4.24 -4.64
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Cyclin associated with protein kinase Kin28p; Kin28p is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters; human homolog CCNH allows growth of yeast ccl1 temperature-sensitive mutant at restrictive temperature
Localization
Cell Percentages nucleus (100%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Ccl1

Ccl1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ccl1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available