Standard name
Human Ortholog
Description Beta 5 subunit of the 20S proteasome; responsible for the chymotryptic activity of the proteasome
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0.06 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Cytoplasm 0.89 0.97 0.96 0.97 0.96 0.92 0.92 – 0.77 0.85 0.72 0.76 1.0 1.0 1.0 0.78 – 0.91 0.78 0.82 0.66 0.83 0.8 0.79
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0.11 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Mitochondria 0.13 0 0 0 0 0.07 0.07 – 0.38 0.22 0.38 0.32 0 0 0 0.26 – 0 0.12 0.06 0.14 0 0.05 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.09 – 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0.05 0 0 0 0 – 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 0 0 0 0 0 – 0 1 0 0 0 0 0 0 – 0 0 4 14 4 3 1
Bud 0 0 0 3 2 2 3 – 7 7 8 18 0 0 0 0 – 1 0 4 11 5 12 14
Bud Neck 0 3 20 12 18 14 22 – 4 4 7 12 0 1 1 0 – 0 2 2 6 1 2 3
Bud Site 0 0 0 0 0 1 0 – 1 0 1 1 0 0 0 0 – 0 – – – – – –
Cell Periphery 2 3 1 4 1 1 1 – 0 2 0 1 0 1 1 0 – 0 0 2 9 2 3 2
Cytoplasm 134 412 564 330 311 542 528 – 295 305 272 361 197 288 270 18 – 32 138 333 367 288 298 277
Endoplasmic Reticulum 0 2 1 0 1 0 0 – 0 0 0 1 0 0 0 0 – 4 0 0 4 3 4 4
Endosome 1 0 6 0 0 3 1 – 1 0 1 0 0 0 0 0 – 0 2 4 8 3 4 4
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 1 3 1 0 1 0
Mitochondria 19 13 0 3 12 44 43 – 146 77 144 151 0 0 0 6 – 1 21 26 79 15 19 15
Nucleus 0 1 1 1 3 1 4 – 2 1 1 5 1 0 0 0 – 1 0 1 0 1 2 2
Nuclear Periphery 0 0 1 0 0 0 1 – 1 0 0 0 0 0 0 1 – 0 0 1 0 0 0 2
Nucleolus 0 1 1 0 3 0 1 – 1 1 0 0 0 0 1 2 – 0 0 0 0 0 1 0
Peroxisomes 0 0 0 0 0 1 0 – 0 0 0 0 0 0 0 0 – 0 0 1 1 0 0 0
SpindlePole 1 0 7 8 2 16 16 – 10 6 16 24 0 0 0 0 – 0 2 4 19 9 4 8
Vac/Vac Membrane 2 2 5 1 1 2 5 – 1 2 3 2 0 0 0 0 – 0 3 7 4 3 4 4
Unique Cell Count 151 425 586 340 323 588 574 383 357 379 478 197 288 271 23 35 178 409 555 349 373 351
Labelled Cell Count 160 437 607 362 354 627 625 469 406 453 576 198 290 273 27 39 178 409 555 349 373 351


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.5 3.2 5.0 4.7 4.3 3.5 4.1 – 3.1 3.4 3.2 3.3 4.8 4.3 4.4 6.0 – 5.4 5.3 5.6 5.7
Std Deviation (1e-4) 0.6 0.8 2.0 2.1 1.9 1.0 1.7 – 1.3 1.2 0.9 1.1 1.4 1.0 1.2 3.2 – 3.1 1.7 2.1 2.0
Intensity Change (Log2) – – – -0.08 -0.19 -0.5 -0.28 – -0.7 -0.56 -0.61 -0.59 -0.04 -0.2 -0.16 0.28 – 0.12 0.09 0.17 0.2

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.481 3.4489 3.5508 3.1572 2.9995 3.3498 3.5263 2.9173 3.283 2.1771 3.1995 3.1493 0.4346 0.687 0.6404 1.0918 -0.0343 0.8079
Actin 0.0319 0.0015 0.0027 0.0044 0.0083 0.0088 0.0178 0.0002 0.0204 0.0003 0.0612 0.0014 0.015 0 0.0035 0.0028 0 0.0303
Bud 0.0008 0.0046 0.0022 0.0002 0.0052 0.0007 0.001 0.0007 0.0007 0.0041 0.0023 0.0007 0.0015 0 0.0002 0.0088 0 0.0025
Bud Neck 0.0011 0.0013 0.003 0.0003 0.0021 0.0003 0.0004 0.0006 0.0012 0.0001 0.0016 0.0002 0.0002 0 0.0016 0.0002 0 0.0012
Bud Periphery 0.0014 0.0025 0.009 0.0003 0.0192 0.003 0.0079 0.0009 0.002 0.0014 0.0041 0.0028 0.0044 0 0.0001 0.016 0 0.0084
Bud Site 0.0107 0.011 0.0091 0.0008 0.0201 0.0007 0.0014 0.0138 0.0055 0.0009 0.0199 0.0002 0.0035 0 0.0004 0.0009 0 0.0008
Cell Periphery 0.0008 0.0004 0.0009 0 0.0009 0 0.0009 0.0002 0.0008 0.0002 0.0004 0.0001 0.0001 0 0 0.0001 0 0.0001
Cytoplasm 0.0256 0.0285 0.0228 0.019 0.0493 0.0262 0.0269 0.0336 0.0304 0.0174 0.0094 0.0368 0.0135 0.0097 0.0096 0.0159 0.0258 0.0221
Cytoplasmic Foci 0.0392 0.0076 0.0124 0.0169 0.0383 0.0134 0.0168 0.0037 0.008 0.0131 0.0302 0.005 0.0123 0.0011 0.0171 0.0251 0.0009 0.0043
Eisosomes 0.0007 0.0002 0.0004 0.0001 0.0002 0.0001 0.0009 0.0001 0.0008 0.0001 0.0004 0.0001 0.0003 0.0001 0.0002 0.0002 0.0001 0.0002
Endoplasmic Reticulum 0.0068 0.0037 0.0016 0.0001 0.0006 0.0006 0.002 0.0002 0.0035 0.0003 0.0011 0.0006 0.0027 0.0001 0.0002 0.0013 0.0003 0.0005
Endosome 0.0229 0.0065 0.008 0.0059 0.0135 0.0101 0.0082 0.0023 0.0081 0.0002 0.0529 0.0116 0.0214 0 0.0037 0.0103 0.0001 0.0023
Golgi 0.008 0.0027 0.0054 0.0249 0.0118 0.0026 0.005 0.0009 0.0015 0.0001 0.0414 0.0032 0.0048 0 0.005 0.0019 0 0.0023
Lipid Particles 0.0141 0.0013 0.0034 0.0006 0.0031 0.0021 0.0115 0.0018 0.0028 0.0004 0.0142 0.0084 0.0081 0.0001 0.0137 0.0158 0.0001 0.0009
Mitochondria 0.0123 0.0008 0.0018 0.0632 0.0226 0.0023 0.0058 0.0007 0.0016 0.0009 0.0097 0.0008 0.0073 0 0.0007 0.0031 0 0.0026
None 0.7686 0.9131 0.9095 0.8529 0.7828 0.9176 0.8395 0.9348 0.8886 0.9544 0.7237 0.9185 0.8661 0.9884 0.9287 0.816 0.9724 0.9162
Nuclear Periphery 0.0086 0.0007 0.0008 0 0.0004 0.0015 0.0075 0.0001 0.0028 0.0003 0.0016 0.0016 0.0171 0 0.0002 0.0109 0.0001 0.0005
Nucleolus 0.0043 0.0007 0.0003 0 0.0005 0.0001 0.0003 0.0011 0.0003 0.001 0.0004 0.0003 0.0006 0 0.0005 0.002 0 0.0001
Nucleus 0.0113 0.001 0.0004 0.0001 0.0006 0.0003 0.0273 0.0005 0.0008 0.0013 0.0004 0.0015 0.0061 0 0.0004 0.0441 0.0001 0.0002
Peroxisomes 0.0136 0.0076 0.003 0.0097 0.0143 0.0066 0.0105 0.0014 0.0177 0.0005 0.0209 0.0029 0.0067 0 0.0094 0.0062 0 0.0035
Punctate Nuclear 0.0133 0.0032 0.0004 0.0002 0.0006 0.0017 0.0067 0.0003 0.0009 0.002 0.0022 0.0021 0.0051 0.0001 0.0045 0.0159 0 0.0005
Vacuole 0.0029 0.0006 0.002 0.0001 0.004 0.0006 0.0008 0.0019 0.0013 0.0007 0.0014 0.0009 0.0021 0.0001 0.0002 0.0015 0 0.0003
Vacuole Periphery 0.0011 0.0001 0.0008 0.0001 0.0016 0.0006 0.0009 0.0001 0.0004 0.0002 0.0008 0.0004 0.001 0 0.0001 0.0009 0 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 135.3714 110.739 106.7403 169.0048 104.3155 112.3216 138.2286 146.0778 146.8094 149.1005
Translational Efficiency 1.9981 2.0491 2.3783 1.4822 1.811 3.0161 2.0349 1.8831 1.798 1.5674

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1428 1910 1293 1887 1799 2082 145 2212 3227 3992 1438 4099

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 635.37 734.62 739.98 722.51 632.91 774.38 775.70 714.35 634.00 755.36 743.58 718.11
Standard Deviation 93.68 82.64 78.78 74.39 69.04 86.87 78.92 66.97 80.88 87.17 79.52 70.60
Intensity Change Log 2 — 0.209401 0.219889 0.185421 — 0.291041 0.293498 0.174631 — 0.250720 0.257092 0.180046

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000065 0.000216 0.000172 0.000091 0.000064 0.000222 0.000101 0.000034 0.000064 0.000219 0.000165 0.000060
Bud Neck 0.019282 0.029287 0.003060 0.004910 0.009400 0.028724 0.000788 0.003527 0.013773 0.028994 0.002831 0.004164
Bud Site 0.002565 0.011438 0.013364 0.008278 0.003717 0.010833 0.000459 0.006300 0.003207 0.011122 0.012063 0.007211
Cell Periphery 0.000573 0.000101 0.000151 0.000110 0.000161 0.000191 0.000317 0.000140 0.000343 0.000148 0.000168 0.000126
Cytoplasm 0.414879 0.448368 0.468369 0.503240 0.518932 0.479422 0.298301 0.532556 0.472887 0.464564 0.451220 0.519060
Cytoplasmic Foci 0.202120 0.205916 0.020606 0.018499 0.145441 0.139663 0.080649 0.031234 0.170522 0.171362 0.026660 0.025371
Eisosomes 0.000551 0.000097 0.000032 0.000027 0.000127 0.000132 0.000168 0.000038 0.000315 0.000116 0.000046 0.000033
Endoplasmic Reticulum 0.002420 0.000862 0.000684 0.000400 0.000536 0.000501 0.000937 0.000484 0.001370 0.000674 0.000710 0.000445
Endosome 0.011354 0.017962 0.001711 0.001541 0.004476 0.010485 0.005472 0.001878 0.007519 0.014062 0.002090 0.001723
Golgi 0.002874 0.003303 0.000058 0.000060 0.000888 0.002092 0.000727 0.000171 0.001767 0.002672 0.000125 0.000120
Lipid Particles 0.023971 0.005513 0.000995 0.000753 0.008140 0.006585 0.010176 0.001067 0.015145 0.006072 0.001921 0.000922
Mitochondria 0.006861 0.008036 0.000507 0.000701 0.004189 0.008466 0.000486 0.000972 0.005372 0.008260 0.000505 0.000847
Mitotic Spindle 0.000641 0.005555 0.003052 0.001664 0.002226 0.007036 0.000087 0.001456 0.001525 0.006327 0.002753 0.001551
None 0.009894 0.002721 0.004884 0.002882 0.003312 0.003566 0.010873 0.003173 0.006225 0.003162 0.005488 0.003039
Nuclear Periphery 0.000955 0.000682 0.000954 0.000836 0.000521 0.000633 0.000886 0.000768 0.000714 0.000656 0.000947 0.000800
Nuclear Periphery Foci 0.000369 0.000277 0.000217 0.000159 0.000179 0.000147 0.001079 0.000131 0.000263 0.000209 0.000304 0.000144
Nucleolus 0.001505 0.001889 0.000567 0.000555 0.000963 0.001689 0.001650 0.000487 0.001203 0.001785 0.000676 0.000518
Nucleus 0.246644 0.172759 0.455107 0.427952 0.271521 0.244208 0.530600 0.384007 0.260512 0.210023 0.462719 0.404237
Peroxisomes 0.008210 0.012956 0.000439 0.000339 0.002735 0.006510 0.000915 0.000319 0.005157 0.009594 0.000487 0.000328
Vacuole 0.043361 0.070061 0.024778 0.026821 0.022025 0.047778 0.055087 0.030993 0.031467 0.058439 0.027834 0.029072
Vacuole Periphery 0.000909 0.002001 0.000293 0.000183 0.000447 0.001116 0.000242 0.000266 0.000651 0.001539 0.000288 0.000228

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.02 -1.23 -0.55 2.51 0.80 -2.20 -1.23 1.49 2.67 1.56 -3.93 -1.38 0.16 3.67 1.39
Bud Neck -4.38 10.78 8.77 12.82 -2.02 -9.94 9.08 6.14 13.90 -4.23 -10.31 12.46 10.60 18.96 -2.28
Bud Site -7.61 -4.29 -3.76 1.93 1.61 -4.75 3.04 -1.78 2.82 -4.84 -8.11 -3.83 -3.76 3.41 1.84
Cell Periphery 12.05 9.88 11.67 -1.03 1.84 -1.65 -5.39 1.16 3.20 6.41 9.65 6.98 10.44 2.29 2.05
Cytoplasm -3.47 -3.42 -9.15 -5.54 -4.48 4.79 10.92 -1.09 -5.83 -11.34 1.53 4.35 -6.69 -8.12 -8.95
Cytoplasmic Foci -0.50 33.04 33.75 38.01 1.02 1.02 8.58 28.24 27.33 6.63 -0.20 40.90 43.53 45.84 0.36
Eisosomes 8.35 9.53 9.64 19.71 2.93 -0.64 -3.22 15.05 15.30 10.77 8.05 10.85 11.49 22.54 5.98
Endoplasmic Reticulum 4.14 4.31 5.40 4.58 5.89 0.20 -2.21 0.14 -0.04 2.36 3.59 2.57 4.51 2.10 4.10
Endosome -4.83 10.88 11.14 15.35 0.88 -7.27 -1.20 6.32 11.17 4.08 -8.43 11.35 12.72 18.88 1.81
Golgi -0.67 6.83 6.82 8.36 -0.17 -2.25 0.51 4.14 3.94 0.92 -2.27 7.97 7.98 8.06 0.02
Lipid Particles 11.63 14.78 14.97 13.44 2.83 2.01 -0.36 10.39 12.84 2.24 10.81 14.94 17.88 18.30 2.44
Mitochondria -0.84 6.58 6.28 8.89 -0.92 -3.16 4.07 3.33 6.97 -1.00 -3.05 7.43 6.55 10.76 -1.39
Mitotic Spindle -4.13 -2.58 -1.64 3.27 1.44 -2.77 0.85 0.97 3.76 -0.19 -4.51 -1.22 0.19 4.97 1.49
None 4.36 3.16 4.29 -0.35 3.24 -0.45 -1.84 0.27 0.67 1.87 3.92 1.17 4.16 0.29 3.56
Nuclear Periphery 2.15 -1.54 0.67 -2.31 4.16 -2.49 -4.18 -7.33 -3.71 2.10 0.78 -6.67 -2.77 -3.89 5.70
Nuclear Periphery Foci 1.41 2.01 3.43 3.76 3.00 1.12 -2.91 1.61 0.38 3.00 1.61 -1.85 3.76 3.23 4.39
Nucleolus -0.60 2.75 2.74 6.38 0.04 -3.01 -1.70 3.88 5.91 2.43 -2.15 2.76 3.96 8.71 1.81
Nucleus 9.92 -21.71 -21.51 -33.44 3.31 3.86 -10.07 -15.45 -19.08 5.33 9.80 -24.23 -26.00 -36.51 7.20
Peroxisomes -3.06 8.03 8.11 10.76 0.26 -5.72 4.74 8.01 11.02 2.04 -5.52 10.01 10.49 14.62 0.86
Vacuole -8.75 3.74 5.34 14.26 1.17 -11.89 -4.58 -6.64 5.85 3.48 -14.56 -2.13 -0.14 14.39 2.04
Vacuole Periphery -4.89 5.09 7.88 8.99 1.10 -6.25 2.63 2.22 7.36 -0.06 -7.43 4.13 6.95 11.47 0.59
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Beta 5 subunit of the 20S proteasome; responsible for the chymotryptic activity of the proteasome
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Pre2

Pre2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pre2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available