ORF
Human Ortholog
Description Putative protein of unknown function
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 0 0.07 0.06 0.06 0 0.06 – 0.08 0.06 0.09 0.05 0.06 0 0 0.11 0.05 0 0 0 0 0 0
Bud – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery – 0 0.07 0.08 0 0.07 0 0.05 – 0.07 0.11 0.12 0.11 0.14 0.24 0.32 0.33 0.36 0 0 0 0 0 0
Cytoplasm – 0.07 0 0.05 0.06 0.11 0.07 0.06 – 0.11 0.08 0.06 0.05 0.07 0.05 0.27 0.17 0.19 0 0 0 0 0 0
Endoplasmic Reticulum – 0.91 0.88 0.81 0.81 0.67 0.75 0.68 – 0.52 0.54 0.63 0.9 0.87 0.84 0 0 0 0.95 0.93 0.93 0.91 0.89 0.87
Endosome – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi – 0 0.05 0.15 0.05 0 0 0 – 0 0 0 0.07 0 0 0.17 0.28 0.36 0 0 0 0 0 0
Mitochondria – 0 0.07 0.06 0.07 0.09 0.22 0.21 – 0.18 0.38 0.35 0 0 0 0 0.1 0 0 0 0 0 0 0
Nucleus – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery – 0 0.11 0.09 0.07 0.06 0.13 0.11 – 0.09 0.07 0.1 0 0 0 0.08 0.05 0 0 0 0 0 0 0
Nucleolus – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane – 0.05 0.07 0 0.09 0.14 0 0.11 – 0.23 0.06 0 0 0 0 0.12 0.06 0.09 0 0 0 0 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 15 9 12 13 16 16 24 – 32 14 30 29 35 26 3 12 5 0 9 2 5 6 6
Bud – 1 2 0 0 3 2 4 – 2 3 5 2 0 0 1 1 0 0 2 0 0 4 4
Bud Neck – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1
Bud Site – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery – 14 17 13 10 19 16 20 – 28 25 37 60 80 140 42 35 34 0 0 1 0 2 5
Cytoplasm – 38 8 8 13 32 27 25 – 44 19 18 24 37 28 35 18 18 0 2 1 4 4 8
Endoplasmic Reticulum – 489 226 137 185 190 279 268 – 216 122 201 475 497 487 3 4 0 30 524 251 392 505 491
Endosome – 0 1 0 1 1 0 0 – 2 0 0 0 0 1 0 0 0 0 2 1 0 1 0
Golgi – 6 12 25 12 1 2 1 – 2 2 2 36 13 15 22 29 34 0 4 1 4 6 6
Mitochondria – 2 18 10 16 25 81 83 – 74 86 110 1 0 0 5 10 4 0 4 4 6 7 7
Nucleus – 1 0 0 0 5 2 1 – 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery – 22 29 15 16 18 48 43 – 36 16 32 16 14 11 11 5 3 0 3 1 4 3 3
Nucleolus – 0 0 0 0 0 1 0 – 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
Peroxisomes – 0 0 0 0 0 0 0 – 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1
SpindlePole – 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane – 29 17 6 20 41 14 45 – 95 13 12 14 17 22 16 6 9 0 5 0 9 20 25
Unique Cell Count 537 257 170 227 283 371 393 415 227 318 528 569 580 130 105 95 32 566 269 433 569 566
Labelled Cell Count 617 339 226 286 351 488 514 531 302 447 658 694 732 138 120 107 32 566 269 433 569 566


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) – 20.8 15.8 15.6 13.5 12.0 11.0 10.9 – 11.4 11.3 11.0 19.4 18.3 18.4 20.1 19.7 20.8 20.8 21.0 20.5
Std Deviation (1e-4) – 3.9 2.7 2.3 2.3 2.0 1.8 1.9 – 2.3 2.3 2.1 3.5 3.5 3.1 4.0 4.4 4.0 3.7 3.8 3.7
Intensity Change (Log2) – – – -0.02 -0.23 -0.39 -0.53 -0.53 – -0.48 -0.48 -0.52 0.3 0.22 0.22 0.34 0.32 0.4 0.4 0.41 0.38

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP70005101520WT3HU80HU120HU16005101520WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305101520AF100AF140AF18005101520
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 1.7 1.2 1.2 0.5 1.5 – 2.2 1.4 2.8 1.2 1.6 0.7 0 2.9 0
Bud 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0.4 -1.1 0 -1.3 -0.8 – 0.1 1.7 2.1 2.1 3.1 6.0 6.6 6.6 6.9
Cytoplasm 0.8 1.4 3.6 2.2 1.8 – 3.5 2.5 1.5 1.0 2.0 1.1 7.0 4.7 5.0
Endoplasmic Reticulum -2.1 -2.0 -5.7 -4.0 -5.8 – -9.5 -8.4 -6.7 0.9 -0.2 -1.5 -16.2 -15.1 -15.3
Endosome 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Golgi 3.6 0.3 -3.3 -3.4 -3.9 – -3.7 -2.5 -3.1 1.2 -1.9 -1.6 4.0 6.3 7.7
Mitochondria -0.5 0 0.8 5.0 4.9 – 4.0 8.3 7.9 -5.8 -6.4 -6.4 -1.2 0.8 -1.0
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery -0.8 -1.6 -2.0 0.6 -0.1 – -1.1 -1.6 -0.5 -4.7 -5.3 -5.9 -0.9 -1.9 -2.4
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole -1.4 0.9 3.0 -1.6 2.1 – 5.5 -0.4 -1.5 -2.7 -2.4 -1.8 1.9 -0.3 0.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 14.9666 16.2587 15.3928 14.9454 14.7873 15.0582 21.7766 21.6758 20.9657 20.4236 19.8383 21.3024 22.9771 22.7489 22.1191 21.7792 21.7082 21.3987
Actin 0.0006 0.0021 0.0023 0.0001 0.0002 0.0002 0.014 0.0004 0.005 0.0041 0.0094 0.0002 0.0003 0.001 0.0001 0 0.0001 0.0002
Bud 0 0.0001 0.0002 0 0 0.0001 0.0001 0 0.0001 0.0001 0.0001 0 0 0.0001 0 0 0 0
Bud Neck 0.0001 0.0006 0.0008 0.0002 0.0001 0.0035 0.0004 0.0003 0.001 0.0004 0.0003 0.0002 0.0001 0.0003 0.0002 0 0.0012 0.0003
Bud Periphery 0 0.0001 0.0004 0.0001 0 0.0002 0.0002 0.0001 0.0003 0.0004 0.0001 0 0 0.0003 0 0 0.0001 0
Bud Site 0.0001 0.0008 0.0023 0 0 0.0001 0.0017 0.0002 0.0014 0.0002 0.001 0 0 0.0024 0 0 0 0
Cell Periphery 0.0007 0.0035 0.0014 0.0007 0.0007 0.0008 0.0006 0.0023 0.0014 0.0044 0.0006 0.0004 0.0038 0.0141 0.002 0.0028 0.0044 0.0017
Cytoplasm 0.024 0.048 0.0357 0.0143 0.0129 0.0131 0.0039 0.0184 0.0036 0.002 0.0052 0.001 0.0064 0.0182 0.0132 0.0008 0.0265 0.0028
Cytoplasmic Foci 0.0021 0.0019 0.0007 0.0002 0.0001 0.0002 0.0047 0.0005 0.0004 0.0078 0.0011 0.0002 0 0.0008 0.0002 0 0 0.0001
Eisosomes 0.0001 0 0 0 0 0 0.0002 0 0.0001 0.0005 0.0002 0 0.0002 0.0001 0 0 0 0
Endoplasmic Reticulum 0.8296 0.8846 0.9221 0.9213 0.9259 0.8949 0.8984 0.9594 0.9661 0.9105 0.9564 0.9754 0.913 0.9206 0.9617 0.9843 0.9295 0.9498
Endosome 0.0094 0.0052 0.004 0.0067 0.0034 0.0042 0.0076 0.0028 0.004 0.0144 0.0059 0.002 0.0004 0.0017 0.0008 0.0001 0.0008 0.0006
Golgi 0.0011 0.0026 0.0005 0.0006 0.0002 0.0006 0.0041 0.0021 0.0016 0.0122 0.0018 0.0011 0.0001 0.0007 0.0001 0 0.0001 0.0001
Lipid Particles 0.0023 0.007 0.0017 0.0044 0.0012 0.0011 0.0044 0.0043 0.0012 0.0073 0.0024 0.0017 0.0007 0.0109 0.0011 0.0007 0.0006 0.0012
Mitochondria 0.0004 0.0002 0.0005 0.0004 0.0001 0.0016 0.0094 0.0006 0.0011 0.0008 0.0005 0.0004 0.0001 0.0002 0.0001 0 0.0001 0
None 0.0027 0.0001 0.0004 0.0004 0.0001 0.0001 0.0011 0 0.0001 0.0004 0.0008 0 0.0002 0.0001 0.0005 0 0 0
Nuclear Periphery 0.1052 0.0283 0.0184 0.0307 0.0449 0.0614 0.0341 0.0054 0.0083 0.0237 0.0093 0.0153 0.0631 0.0135 0.0111 0.0098 0.029 0.0372
Nucleolus 0.0001 0 0.0001 0 0 0.0001 0.0004 0 0.0001 0.0001 0.0001 0 0.0002 0.0001 0 0 0 0
Nucleus 0.0119 0.0044 0.0035 0.0039 0.0058 0.0094 0.0042 0.0004 0.0006 0.0006 0.0012 0.0003 0.0067 0.0015 0.0061 0.0002 0.0021 0.0019
Peroxisomes 0.0001 0 0.0005 0 0 0 0.001 0 0.0001 0.0022 0.0001 0 0 0.0001 0 0 0 0
Punctate Nuclear 0.002 0.0002 0.0007 0.0001 0.0002 0.0001 0.0063 0.0001 0.0001 0.0009 0.0005 0 0.0002 0.0005 0.0001 0 0 0
Vacuole 0.0051 0.0096 0.0035 0.0118 0.0035 0.0066 0.0022 0.0025 0.0028 0.0032 0.0026 0.0014 0.0037 0.0107 0.0024 0.0009 0.0049 0.0034
Vacuole Periphery 0.0024 0.0007 0.0004 0.004 0.0008 0.0018 0.001 0.0002 0.0006 0.0041 0.0003 0.0004 0.0008 0.0022 0.0003 0.0002 0.0004 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 72.7455 62.4289 50.9574 62.5844 61.1179 68.6338 64.9628 69.5848 57.6345 76.6696
Translational Efficiency 0.6191 0.5967 0.7258 0.5363 0.6581 0.733 0.6401 0.489 0.6339 0.5117

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2360 1533 152 1840 1898 1544 318 1668 4258 3077 470 3508

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1460.35 1516.81 1929.66 1686.40 1462.55 1381.00 2044.19 1777.87 1461.33 1448.66 2007.15 1729.89
Standard Deviation 250.39 299.45 262.32 345.16 252.80 279.09 340.59 361.89 251.47 297.27 321.89 356.16
Intensity Change Log 2 — 0.054726 0.402032 0.207633 — -0.082773 0.483043 0.281664 — -0.012437 0.443137 0.245151

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000039 0.000534 0.000331 0.001463 0.000101 0.000931 0.000738 0.000916 0.000067 0.000733 0.000607 0.001203
Bud Neck 0.000062 0.000391 0.005842 0.003101 0.000058 0.000218 0.001802 0.001926 0.000060 0.000304 0.003108 0.002542
Bud Site 0.000461 0.000811 0.002628 0.010561 0.000477 0.002312 0.001540 0.007656 0.000468 0.001564 0.001892 0.009180
Cell Periphery 0.000717 0.000903 0.007708 0.006140 0.001441 0.001728 0.005585 0.003898 0.001040 0.001317 0.006272 0.005074
Cytoplasm 0.000978 0.001411 0.001740 0.010354 0.001323 0.002917 0.001087 0.010905 0.001132 0.002166 0.001298 0.010616
Cytoplasmic Foci 0.000341 0.001155 0.000406 0.002376 0.000967 0.002031 0.000134 0.002453 0.000620 0.001595 0.000222 0.002413
Eisosomes 0.000010 0.000029 0.000461 0.000098 0.000048 0.000059 0.000087 0.000052 0.000027 0.000044 0.000208 0.000076
Endoplasmic Reticulum 0.988852 0.974896 0.849209 0.880662 0.985596 0.964137 0.944945 0.886991 0.987400 0.969497 0.913983 0.883671
Endosome 0.002697 0.006084 0.017584 0.013291 0.002754 0.007045 0.007110 0.015574 0.002722 0.006566 0.010498 0.014377
Golgi 0.000452 0.001318 0.001374 0.005636 0.001030 0.002838 0.004126 0.005580 0.000710 0.002081 0.003236 0.005609
Lipid Particles 0.000648 0.001742 0.014593 0.012638 0.000970 0.002315 0.006401 0.009285 0.000791 0.002030 0.009051 0.011044
Mitochondria 0.000307 0.000236 0.000164 0.001996 0.000765 0.001382 0.000210 0.002099 0.000511 0.000811 0.000195 0.002045
Mitotic Spindle 0.000013 0.000101 0.001410 0.004889 0.000145 0.000089 0.000146 0.003010 0.000072 0.000095 0.000554 0.003996
None 0.001348 0.001828 0.000026 0.002205 0.000973 0.002040 0.000192 0.001832 0.001181 0.001934 0.000138 0.002028
Nuclear Periphery 0.000779 0.001073 0.028202 0.003388 0.000713 0.001588 0.002637 0.004428 0.000750 0.001332 0.010905 0.003882
Nuclear Periphery Foci 0.001524 0.004207 0.056621 0.020763 0.001233 0.005301 0.008581 0.023598 0.001394 0.004756 0.024117 0.022111
Nucleolus 0.000003 0.000004 0.000012 0.000054 0.000009 0.000017 0.000007 0.000063 0.000005 0.000011 0.000008 0.000058
Nucleus 0.000028 0.000067 0.000524 0.001487 0.000169 0.000166 0.000134 0.000948 0.000091 0.000117 0.000260 0.001231
Peroxisomes 0.000111 0.000190 0.000009 0.000188 0.000176 0.000147 0.000011 0.000142 0.000140 0.000169 0.000010 0.000166
Vacuole 0.000432 0.002352 0.010810 0.016163 0.000594 0.001851 0.011850 0.015066 0.000504 0.002101 0.011514 0.015641
Vacuole Periphery 0.000199 0.000668 0.000346 0.002545 0.000458 0.000888 0.002678 0.003578 0.000315 0.000779 0.001924 0.003036

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.00 -2.68 -5.57 -2.80 -3.40 -2.68 -1.26 -4.27 -0.17 -0.16 -3.36 -1.63 -7.02 -2.15 -1.19
Bud Neck -1.61 -2.50 -8.35 -5.76 1.75 -3.30 -2.33 -5.79 -5.30 -0.07 -2.08 -3.12 -10.14 -7.78 1.41
Bud Site -0.98 -2.01 -8.04 -7.77 -1.49 -3.13 -2.02 -6.21 -4.35 -4.53 -3.09 -2.67 -10.14 -8.61 -4.62
Cell Periphery -0.93 -1.47 -9.45 -8.68 0.29 -0.55 -4.06 -5.50 -3.75 1.59 -1.01 -3.15 -11.00 -8.84 0.67
Cytoplasm -2.29 -1.55 -9.79 -9.30 -4.99 -2.56 -0.67 -7.90 -6.19 -6.00 -3.20 -1.48 -12.40 -10.54 -8.03
Cytoplasmic Foci -1.95 -0.88 -5.51 -2.36 -4.13 -1.86 2.10 -3.00 -0.89 -6.11 -2.82 1.59 -5.93 -2.25 -7.72
Eisosomes -1.77 -1.14 -3.69 -2.70 0.90 -0.36 -1.43 -0.21 0.27 1.71 -1.15 -1.42 -3.14 -1.94 1.01
Endoplasmic Reticulum 5.51 6.70 19.51 15.86 -1.78 5.91 5.23 16.97 12.29 5.42 8.19 8.38 25.91 19.86 2.43
Endosome -6.48 -5.64 -12.90 -7.71 1.63 -6.80 -4.04 -14.03 -8.17 -6.06 -9.41 -6.82 -19.05 -11.17 -2.90
Golgi -1.98 -2.29 -5.78 -4.38 -4.34 -2.64 -3.07 -4.53 -2.42 -1.05 -3.41 -3.70 -7.32 -4.70 -2.51
Lipid Particles -2.78 -2.36 -9.14 -8.10 0.42 -1.90 -2.66 -8.15 -6.14 -1.15 -3.11 -3.49 -12.18 -10.10 -0.62
Mitochondria 0.79 0.45 -5.12 -5.43 -5.14 -0.75 1.05 -1.79 -0.86 -3.38 -0.76 1.18 -4.00 -2.80 -5.76
Mitotic Spindle -1.88 -1.92 -4.49 -4.40 -0.44 0.70 -0.90 -3.92 -4.00 -2.41 -0.63 -2.13 -5.91 -5.87 -2.24
None -0.66 5.03 -1.72 -0.48 -5.08 -1.01 1.45 -1.35 0.20 -4.39 -1.19 3.67 -2.15 -0.16 -6.56
Nuclear Periphery -1.07 -3.90 -5.68 -4.76 3.50 -1.88 -3.40 -5.04 -3.86 -2.03 -2.21 -4.35 -7.44 -5.91 2.91
Nuclear Periphery Foci -3.42 -4.98 -10.21 -8.38 3.08 -4.38 -2.94 -10.76 -8.14 -4.53 -5.52 -5.58 -14.81 -11.65 0.30
Nucleolus -1.08 -1.73 -3.54 -3.43 -0.68 -0.80 0.35 -3.63 -2.61 -3.82 -0.99 -1.69 -5.09 -4.18 -3.39
Nucleus -1.50 -2.51 -5.65 -5.48 -1.32 -0.02 -0.19 -4.81 -5.26 -4.94 -0.69 -2.59 -7.29 -7.21 -4.14
Peroxisomes -0.82 2.90 -1.46 0.03 -3.44 0.27 2.20 0.40 0.06 -5.01 -0.42 3.39 -0.59 0.04 -5.56
Vacuole -3.35 -5.51 -10.73 -8.73 -1.54 -3.16 -4.08 -10.30 -9.19 -0.52 -4.54 -5.68 -14.84 -12.60 -1.19
Vacuole Periphery -2.15 -1.82 -6.60 -4.61 -6.05 -1.72 -2.09 -4.71 -4.03 -0.76 -2.86 -2.26 -7.45 -5.91 -1.43
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative protein of unknown function
Localization
Cell Percentages ER (100%)
Cell Cycle Regulation No
Subcompartmental Group ER-5

YPR114W

YPR114W


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ypr114w-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available