Standard name
Human Ortholog
Description Putative regulator of the Fps1p glycerol channel; multiply phosphorylated by Hog1p under osmotic stress; contains a pleckstrin homology domain; forms homodimers and heterodimerizes with paralog Ask10p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Bud 0 0 0 0 0 0 0 0 0.06 0.06 0.07 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.05 0 0 0.12 0.14 0.15 0.12 0.07 0.11 0.14 0.15 0.14 0.12 0.09 0.13 0.14 0.13 0.19 0 0 0.07 0.06 0.07 0.1
Cytoplasm 0.97 0.97 0.97 0.96 0.93 0.84 0.77 0.76 0.65 0.66 0.64 0.63 0.98 1.0 0.98 0.94 0.92 0.95 0.9 0.85 0.71 0.8 0.78 0.73
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.09 0.09 0.22 0.24 0.31 0.46 0.47 0.47 0.51 0 0 0 0 0 0 0 0 0.1 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 4 7 11 12 7 7 9 6 6 0 0 1 0 0 0 1 3 10 3 4 13
Bud 0 1 6 8 10 18 19 30 26 35 24 26 2 2 7 0 0 0 0 0 0 0 3 0
Bud Neck 0 0 2 0 3 0 1 1 0 0 0 0 0 0 0 1 0 0 2 5 9 2 4 7
Bud Site 0 0 0 0 2 0 0 0 2 0 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 8 7 11 45 65 70 76 55 48 83 55 57 17 20 34 16 18 35 3 3 25 5 11 25
Cytoplasm 165 190 343 348 419 386 477 568 298 394 234 262 140 232 248 111 131 172 156 172 243 74 132 184
Endoplasmic Reticulum 2 2 2 2 0 2 4 2 0 8 2 4 2 0 0 1 9 5 1 1 5 1 0 6
Endosome 1 0 1 0 0 0 2 0 0 0 0 0 0 0 0 0 2 0 1 1 2 0 1 1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 3 0 0 0 0 1 0
Mitochondria 0 7 9 33 40 100 149 230 210 283 173 210 1 0 6 2 1 4 3 9 33 2 3 8
Nucleus 0 0 0 1 0 1 1 7 3 3 3 0 0 1 0 0 1 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 2 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 1
Nucleolus 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
SpindlePole 1 0 0 1 1 0 0 6 2 2 1 0 0 0 0 0 0 1 1 0 2 0 0 0
Vac/Vac Membrane 0 0 0 1 1 0 1 5 1 2 1 2 0 0 1 3 6 6 0 1 2 1 4 0
Unique Cell Count 170 196 353 363 452 461 617 751 455 598 365 415 143 233 253 118 143 182 174 203 343 93 170 254
Labelled Cell Count 177 207 375 443 548 588 742 915 598 819 500 569 162 255 297 135 170 226 174 203 343 93 170 254


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.6 4.2 3.9 4.0 4.6 4.3 4.2 4.2 3.9 3.9 4.0 3.7 5.1 5.1 4.8 6.9 7.6 7.5 5.4 5.7 6.6
Std Deviation (1e-4) 0.7 0.6 0.7 1.5 1.7 1.2 1.1 1.2 1.2 1.0 1.2 0.9 0.9 0.7 0.9 1.3 2.3 1.9 1.3 1.3 1.1
Intensity Change (Log2) – – – 0.03 0.24 0.16 0.11 0.12 0.01 0.02 0.05 -0.06 0.39 0.41 0.29 0.83 0.97 0.94 0.48 0.55 0.76

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.4977 1.2639 1.2153 0.7469 0.885 1.0346 1.4094 1.5869 1.3088 0.5209 1.0591 1.5007 1.6438 3.1333 2.2853 2.3694 2.5115 2.4385
Actin 0.0638 0.0021 0.0054 0.0011 0.061 0.0051 0.0646 0.0012 0.0242 0.0043 0.0127 0.023 0.0008 0.0004 0.0101 0.0201 0.0208 0.002
Bud 0.0007 0.0002 0.0043 0.0003 0.0007 0.0006 0.0083 0.0078 0.0098 0.0106 0.0065 0.0051 0.0001 0.0002 0.0009 0.0081 0.0015 0.0002
Bud Neck 0.0018 0.0004 0.0003 0.0002 0.0009 0.0069 0.0018 0.0003 0.0117 0.0001 0.0011 0.0019 0.0001 0.0001 0.0003 0.0093 0.0028 0.0006
Bud Periphery 0.001 0.0003 0.0017 0.0003 0.0012 0.0006 0.0145 0.0069 0.008 0.0547 0.0178 0.007 0.0001 0.0004 0.0019 0.0197 0.0044 0.0014
Bud Site 0.0036 0.0098 0.0076 0.0002 0.0018 0.0003 0.0104 0.0239 0.0302 0.0005 0.0029 0.0019 0.0004 0.0017 0.0022 0.0044 0.0007 0
Cell Periphery 0.0017 0.0013 0.0007 0.0003 0.0003 0.0003 0.0007 0.0011 0.0014 0.0001 0.0005 0.0004 0.0006 0.0015 0.0007 0.0007 0.0004 0.0004
Cytoplasm 0.3426 0.5407 0.572 0.5916 0.4589 0.6182 0.244 0.4208 0.3951 0.4696 0.2496 0.5509 0.3378 0.3609 0.4258 0.3953 0.4079 0.4973
Cytoplasmic Foci 0.0465 0.0043 0.0174 0.0083 0.0107 0.017 0.0462 0.0036 0.021 0.0036 0.0112 0.0164 0.0036 0.0022 0.0061 0.0348 0.0373 0.0036
Eisosomes 0.0004 0.0002 0.0002 0 0.0006 0.0001 0.0007 0.0001 0.0006 0.0001 0.0001 0.0001 0.0002 0.0002 0.0004 0.0005 0.0003 0.0002
Endoplasmic Reticulum 0.008 0.0034 0.0042 0.0072 0.0029 0.0035 0.009 0.0019 0.0036 0.001 0.0072 0.0019 0.003 0.001 0.0028 0.0042 0.0063 0.0014
Endosome 0.0431 0.0013 0.006 0.0119 0.0084 0.0027 0.042 0.0007 0.0128 0.0012 0.0569 0.0075 0.0005 0.0003 0.0023 0.0179 0.0168 0.0009
Golgi 0.0094 0.0002 0.0026 0.0008 0.0079 0.0011 0.0144 0.0002 0.0033 0.0003 0.0077 0.0068 0.0002 0.0001 0.0008 0.0107 0.0138 0.0001
Lipid Particles 0.0137 0.0006 0.0028 0.0011 0.0139 0.0005 0.0169 0.0003 0.0055 0.0001 0.0136 0.0075 0.0004 0.0001 0.0006 0.0113 0.0093 0.0001
Mitochondria 0.0039 0.0001 0.0047 0.0005 0.0041 0.0008 0.0226 0.0004 0.0105 0.0033 0.0033 0.0022 0.0001 0.0001 0.0026 0.0155 0.0093 0.0002
None 0.3901 0.432 0.3617 0.3697 0.4014 0.3373 0.4291 0.5274 0.448 0.4475 0.5877 0.3583 0.6507 0.6294 0.5357 0.4162 0.4498 0.4893
Nuclear Periphery 0.0157 0.0004 0.0018 0.0018 0.0038 0.0018 0.0266 0.0003 0.0012 0.0004 0.0021 0.0009 0.0002 0.0001 0.0005 0.0083 0.0058 0.0002
Nucleolus 0.0012 0.0001 0.0003 0.0001 0.0006 0.0001 0.0014 0.0002 0.0007 0.0001 0.0007 0.0001 0.0001 0.0001 0.0001 0.0011 0.0002 0.0001
Nucleus 0.0042 0.0006 0.0009 0.0008 0.0009 0.0006 0.0066 0.0009 0.0017 0.0005 0.001 0.0009 0.0003 0.0002 0.0006 0.0023 0.0007 0.0003
Peroxisomes 0.0078 0.0001 0.0025 0.0001 0.0085 0.0009 0.0229 0.0002 0.004 0.0007 0.0041 0.005 0.0001 0.0001 0.0041 0.01 0.0072 0.0001
Punctate Nuclear 0.021 0.0003 0.0015 0.0006 0.0106 0.0008 0.0108 0.0006 0.0023 0.0002 0.0009 0.001 0.0002 0.0001 0.0004 0.006 0.0012 0.0007
Vacuole 0.0174 0.0014 0.0011 0.0028 0.0007 0.0007 0.0033 0.0012 0.0039 0.0011 0.0101 0.001 0.0005 0.0009 0.0009 0.0025 0.0018 0.0007
Vacuole Periphery 0.0024 0.0001 0.0003 0.0004 0.0004 0.0002 0.0031 0.0001 0.0007 0.0002 0.0021 0.0002 0 0 0.0001 0.0012 0.0017 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 16.965 17.8955 17.7807 24.8895 18.2566 21.3641 21.0843 23.9072 24.5265 25.3627
Translational Efficiency 0.2281 0.2136 0.2648 0.2247 0.2644 0.2268 0.2168 0.2019 0.3098 0.2534

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1926 1005 148 966 1449 1044 369 226 3375 2049 517 1192

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 699.30 702.68 1163.31 832.67 612.92 771.64 1017.38 882.95 662.21 737.82 1059.15 842.20
Standard Deviation 76.38 90.70 139.79 113.49 77.03 100.59 104.35 95.38 87.78 101.87 133.10 112.03
Intensity Change Log 2 — 0.006956 0.734252 0.251833 — 0.332229 0.731088 0.526633 — 0.168040 0.732775 0.386720

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000478 0.001072 0.001574 0.001437 0.000253 0.000909 0.000555 0.001052 0.000382 0.000989 0.000847 0.001364
Bud Neck 0.020780 0.035075 0.003506 0.006803 0.011787 0.036282 0.002223 0.002209 0.016919 0.035690 0.002590 0.005932
Bud Site 0.009717 0.022395 0.020248 0.031836 0.006377 0.026066 0.007666 0.013560 0.008283 0.024265 0.011268 0.028371
Cell Periphery 0.000705 0.000290 0.000676 0.000431 0.000209 0.000326 0.000388 0.000261 0.000492 0.000308 0.000470 0.000399
Cytoplasm 0.577666 0.440807 0.395217 0.504092 0.516410 0.499158 0.476041 0.479432 0.551367 0.470538 0.452903 0.499416
Cytoplasmic Foci 0.182467 0.281306 0.073645 0.036901 0.247658 0.230339 0.045730 0.031948 0.210456 0.255337 0.053721 0.035962
Eisosomes 0.001514 0.000599 0.000136 0.000168 0.000377 0.000649 0.000130 0.000123 0.001026 0.000624 0.000132 0.000160
Endoplasmic Reticulum 0.001409 0.001069 0.008680 0.002569 0.001793 0.000469 0.004329 0.002085 0.001574 0.000763 0.005575 0.002477
Endosome 0.008793 0.041345 0.013164 0.006625 0.018719 0.026497 0.007353 0.001717 0.013054 0.033780 0.009017 0.005694
Golgi 0.004642 0.008177 0.000387 0.003836 0.003840 0.009806 0.000126 0.000063 0.004298 0.009007 0.000201 0.003121
Lipid Particles 0.006788 0.008799 0.006295 0.001487 0.014710 0.004720 0.003434 0.001217 0.010189 0.006721 0.004253 0.001436
Mitochondria 0.002218 0.005907 0.000122 0.001706 0.002674 0.005088 0.000125 0.000084 0.002413 0.005490 0.000124 0.001398
Mitotic Spindle 0.000949 0.000758 0.002434 0.021837 0.000191 0.003587 0.000444 0.000405 0.000623 0.002199 0.001013 0.017774
None 0.006311 0.001337 0.000652 0.005130 0.008401 0.001426 0.001643 0.001879 0.007208 0.001382 0.001359 0.004514
Nuclear Periphery 0.000126 0.000338 0.001021 0.000660 0.000474 0.000106 0.001006 0.000531 0.000275 0.000220 0.001010 0.000636
Nuclear Periphery Foci 0.000652 0.000467 0.024142 0.001950 0.001121 0.000265 0.006647 0.001578 0.000854 0.000364 0.011656 0.001879
Nucleolus 0.000860 0.000985 0.000168 0.000247 0.002099 0.000585 0.000218 0.000074 0.001392 0.000781 0.000203 0.000214
Nucleus 0.110191 0.039616 0.094286 0.164722 0.085707 0.043996 0.160015 0.127914 0.099679 0.041848 0.141199 0.157743
Peroxisomes 0.003314 0.013281 0.000578 0.002982 0.003653 0.008966 0.000331 0.000230 0.003460 0.011083 0.000402 0.002461
Vacuole 0.059839 0.094389 0.352773 0.203991 0.072304 0.098450 0.281448 0.333587 0.065191 0.096458 0.301866 0.228562
Vacuole Periphery 0.000581 0.001988 0.000296 0.000592 0.001245 0.002310 0.000148 0.000051 0.000866 0.002152 0.000190 0.000489

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.46 -7.57 -1.49 0.22 2.02 -2.81 -3.30 -1.70 0.43 -0.73 -2.63 -5.85 -2.03 0.21 -0.23
Bud Neck -5.48 14.02 11.50 11.95 -1.64 -9.84 9.42 8.79 14.42 -0.74 -10.40 18.25 12.10 17.39 -3.24
Bud Site -6.60 -5.03 -3.90 1.23 0.61 -7.99 -0.60 -1.53 3.59 -1.32 -10.15 -2.53 -4.67 2.84 -3.12
Cell Periphery 9.69 1.02 6.37 -0.32 4.20 -2.88 -3.44 0.09 2.50 2.87 6.02 2.09 4.16 0.36 2.47
Cytoplasm 14.37 11.49 16.98 3.06 -2.47 1.60 7.27 7.87 6.81 1.85 11.51 13.64 17.04 7.40 -0.39
Cytoplasmic Foci -13.45 17.84 40.37 37.86 5.78 2.20 37.50 38.51 30.01 1.97 -8.35 42.62 55.58 48.26 5.49
Eisosomes 6.50 15.13 13.99 3.94 -0.29 -3.20 4.82 4.92 7.55 0.59 4.72 15.61 13.77 6.86 -0.29
Endoplasmic Reticulum 0.69 -6.07 -4.10 -6.71 4.67 5.75 -6.71 -2.17 -7.55 4.81 2.78 -8.66 -5.19 -11.25 5.97
Endosome -11.59 -2.54 5.95 13.48 6.94 -3.99 11.29 17.53 14.43 7.96 -12.17 6.95 13.53 18.25 6.64
Golgi -4.68 14.62 4.14 6.77 -1.62 -5.43 13.60 13.77 9.15 4.87 -6.99 20.15 5.08 9.07 -1.84
Lipid Particles -2.27 1.42 13.73 8.53 8.23 9.99 12.25 14.43 7.37 5.76 5.37 12.33 18.88 10.85 9.09
Mitochondria -3.00 5.33 2.91 4.25 -2.83 -2.29 6.77 6.88 5.09 3.17 -3.80 8.27 4.93 6.08 -2.77
Mitotic Spindle 0.35 -2.08 -4.77 -4.93 -3.64 -2.91 -1.78 -2.45 1.88 -1.46 -2.29 -1.57 -5.01 -4.09 -4.66
None 7.98 9.81 3.38 -3.19 -4.60 5.44 5.69 5.58 0.00 -0.35 8.84 9.61 5.16 -3.09 -3.79
Nuclear Periphery -1.84 -9.42 -18.98 -5.91 0.69 6.44 -8.92 -3.82 -11.24 5.22 0.86 -15.27 -15.52 -11.39 2.77
Nuclear Periphery Foci 2.40 -13.51 -10.28 -11.53 12.58 8.51 -8.51 -3.85 -8.38 6.78 8.07 -14.19 -9.93 -14.60 12.32
Nucleolus -0.72 7.62 6.80 3.08 -1.62 5.10 6.70 7.05 5.68 4.61 2.91 9.08 8.88 4.35 -0.49
Nucleus 21.52 2.01 -11.12 -21.22 -8.77 11.97 -9.53 -3.50 -7.71 4.05 24.29 -7.13 -12.62 -22.55 -2.58
Peroxisomes -7.55 11.49 4.28 8.81 -1.88 -5.60 9.31 9.41 9.93 1.13 -9.45 14.98 6.08 11.81 -2.26
Vacuole -8.64 -17.47 -27.31 -22.26 4.11 -5.75 -19.27 -19.04 -17.56 -4.58 -10.48 -25.71 -32.07 -27.55 1.18
Vacuole Periphery -7.20 4.72 2.60 8.15 -0.10 -1.75 12.62 13.56 3.76 7.45 -3.96 13.17 6.64 5.80 -0.87
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative regulator of the Fps1p glycerol channel; multiply phosphorylated by Hog1p under osmotic stress; contains a pleckstrin homology domain; forms homodimers and heterodimerizes with paralog Ask10p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
Localization
Cell Percentages cytoplasm (66%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-10

Rgc1

Rgc1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rgc1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available