Standard name
Human Ortholog
Description Protein of unknown function; required for efficient 5' processing of mitochondrial tRNAs, for respiratory growth and mitochondrial genome maintenance; null mutation results in a decrease in plasma membrane electron transport; localizes to the matrix side of the inner mitochondrial membrane
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 – 0.06 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 0.32 0.15 – 0.12 0.47 0.27 0.27 0.31 0.18 0.19 0.13 0.11 0.39 0.6 0.7 – 0.49 0.53 0.11 0.05 0 0 0.09 0.09
Endoplasmic Reticulum 0 0.05 – 0 0 0 0 0 0 0 0 0 0 0.11 0 – 0.07 0 0 0 0 0 0 0
Endosome 0 0 – 0 0.1 0.22 0.14 0.1 0 0 0 0 0.26 0.07 0.13 – 0.1 0.12 0.06 0.09 0 0.09 0.07 0.07
Golgi 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0.06 0 0 0 0 0 0
Mitochondria 0.55 0.72 – 0.81 0.19 0.42 0.49 0.46 0.8 0.78 0.87 0.85 0.28 0.1 0 – 0.15 0.09 0.62 0.68 0.82 0.68 0.66 0.58
Nucleus 0 0 – 0.06 0 0 0 0 0.08 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 – 0 0.16 0.13 0.1 0 0 0 0 0 0.14 0 0 – 0.11 0 0 0 0 0.05 0 0
SpindlePole 0.06 0 – 0 0.08 0 0.16 0.14 0 0.06 0.07 0.11 0.06 0.07 0.05 – 0.12 0.06 0.06 0 0 0 0 0
Vac/Vac Membrane 0.09 0.19 – 0 0.13 0.07 0.11 0.11 0 0.05 0 0 0.07 0 0 – 0.06 0.19 0.05 0.05 0 0 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 – 0 0 0 0 0 0 0 0 0 1 2 1 – 0 0 1 2 0 4 6 5
Bud 1 1 – 1 0 3 4 3 4 0 3 7 2 0 1 – 1 1 1 1 0 1 3 5
Bud Neck 1 0 – 0 0 2 0 1 0 1 0 1 0 1 1 – 1 0 1 0 0 0 1 2
Bud Site 0 0 – 0 0 1 0 1 0 0 1 4 0 0 0 – 0 1 – – – – – –
Cell Periphery 0 2 – 0 0 0 2 0 1 0 0 2 1 2 2 – 2 0 0 0 0 0 0 0
Cytoplasm 17 13 – 2 29 36 43 55 18 18 10 19 27 75 151 – 39 17 13 6 0 5 19 25
Endoplasmic Reticulum 2 4 – 0 0 0 0 1 0 1 0 0 0 14 7 – 6 1 1 0 0 0 1 3
Endosome 1 3 – 0 6 30 22 18 2 3 0 3 18 9 29 – 8 4 7 10 1 10 16 19
Golgi 0 0 – 0 1 0 0 0 0 0 0 0 0 0 0 – 3 2 0 1 0 2 1 4
Mitochondria 29 62 – 13 12 56 79 81 82 74 66 152 19 13 7 – 12 3 78 76 32 84 146 163
Nucleus 0 0 – 1 0 6 5 6 8 1 2 3 0 1 2 – 0 1 0 0 0 0 1 2
Nuclear Periphery 0 1 – 0 0 0 0 0 1 1 0 1 0 0 0 – 0 0 0 0 0 0 1 1
Nucleolus 0 0 – 0 0 0 1 2 1 0 1 4 0 0 0 – 0 0 0 0 0 0 1 1
Peroxisomes 0 2 – 0 10 17 16 7 0 2 0 6 10 5 8 – 9 1 2 3 1 6 3 8
SpindlePole 3 0 – 0 5 6 25 24 2 6 5 19 4 9 11 – 10 2 7 1 0 2 5 11
Vac/Vac Membrane 5 16 – 0 8 9 18 19 4 5 0 8 5 5 6 – 5 6 6 5 0 3 8 17
Unique Cell Count 53 86 16 62 134 160 177 102 95 76 178 69 124 216 80 32 128 113 39 124 223 280
Labelled Cell Count 59 105 17 71 166 215 218 123 112 88 229 87 136 226 96 39 128 113 39 124 223 280


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.9 4.1 – 4.7 7.2 5.5 5.5 5.9 4.8 4.7 4.1 4.4 5.2 5.2 5.0 – 5.3 5.6 5.9 5.8 6.0
Std Deviation (1e-4) 0.6 1.0 – 1.0 4.2 2.4 2.6 2.7 2.7 2.1 1.6 1.9 1.5 0.7 1.2 – 2.5 2.3 1.9 1.8 1.9
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –

RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510HU80HU120HU1600510rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.0101 1.6843 1.1486 1.0662 0.709 1.3134 2.4574 2.4433 2.389 2.4559 3.0494 2.3683 -0.5265 -0.3461 -0.5946 -0.6062 -0.6877 -0.6881
Actin 0.0444 0.0041 0.0167 0.0035 0.0415 0.0145 0.0564 0.0327 0.0426 0.0168 0.02 0.0117 0.0645 0.0091 0.0355 0.0875 0.0551 0.0381
Bud 0.0007 0.0013 0.0033 0.0008 0.001 0.0009 0.0012 0.0049 0.0042 0.0009 0.0006 0.0007 0.0007 0.0021 0.0039 0.002 0.0037 0.0014
Bud Neck 0.0064 0.0025 0.0114 0.0015 0.0021 0.0119 0.0032 0.0012 0.0019 0.0016 0.0017 0.0067 0.0041 0.0105 0.0082 0.0018 0.0064 0.0172
Bud Periphery 0.0018 0.0033 0.0066 0.0025 0.0024 0.004 0.0024 0.0112 0.0103 0.0022 0.0014 0.0019 0.001 0.0045 0.0064 0.0051 0.0096 0.004
Bud Site 0.009 0.0232 0.0226 0.002 0.0021 0.0019 0.0126 0.0366 0.0212 0.003 0.0011 0.001 0.0113 0.0465 0.0286 0.0026 0.0218 0.0028
Cell Periphery 0.0023 0.0032 0.0041 0.001 0.0009 0.0028 0.0018 0.0081 0.0029 0.0009 0.0007 0.0005 0.0006 0.0024 0.0014 0.0015 0.0029 0.0028
Cytoplasm 0.0224 0.0449 0.0112 0.051 0.0519 0.0309 0.0387 0.0615 0.0429 0.0144 0.1018 0.0202 0.035 0.0476 0.0571 0.0546 0.0253 0.0455
Cytoplasmic Foci 0.1093 0.1239 0.0757 0.0385 0.0794 0.1029 0.1507 0.0901 0.0987 0.0963 0.0835 0.1046 0.1423 0.0944 0.1185 0.0365 0.0769 0.0781
Eisosomes 0.004 0.003 0.0024 0.0007 0.0007 0.0011 0.0011 0.0034 0.002 0.0013 0.0004 0.0005 0.0006 0.0012 0.0008 0.001 0.0023 0.0005
Endoplasmic Reticulum 0.0052 0.0232 0.0031 0.0011 0.0081 0.002 0.0064 0.0032 0.0095 0.0012 0.0018 0.0015 0.0063 0.0042 0.0064 0.0041 0.0035 0.0043
Endosome 0.0842 0.1087 0.0571 0.0241 0.1113 0.09 0.0954 0.074 0.0934 0.0902 0.0376 0.0881 0.1838 0.1846 0.1203 0.1125 0.106 0.1601
Golgi 0.0391 0.0414 0.0484 0.0248 0.0743 0.0467 0.0697 0.0715 0.0768 0.0532 0.0549 0.0713 0.0861 0.1102 0.0558 0.0334 0.0931 0.0962
Lipid Particles 0.0931 0.025 0.0299 0.0252 0.0557 0.0371 0.0698 0.0267 0.0185 0.0056 0.095 0.0247 0.1245 0.0227 0.0401 0.0327 0.0277 0.0189
Mitochondria 0.3636 0.4004 0.5612 0.6358 0.4119 0.4501 0.3202 0.4261 0.4119 0.4098 0.4291 0.512 0.1896 0.2736 0.3814 0.565 0.4352 0.4344
None 0.0959 0.0907 0.0304 0.0831 0.044 0.1184 0.029 0.0545 0.0646 0.1954 0.0736 0.0474 0.0397 0.1173 0.0643 0.0204 0.047 0.0217
Nuclear Periphery 0.003 0.0051 0.004 0.0002 0.0049 0.0012 0.0033 0.0008 0.0008 0.0004 0.0005 0.0003 0.0072 0.0006 0.0035 0.0017 0.0007 0.0028
Nucleolus 0.0033 0.0022 0.002 0.0004 0.0006 0.0013 0.0009 0.0008 0.0006 0.0006 0.0003 0.0003 0.0009 0.0012 0.0008 0.0006 0.0006 0.0013
Nucleus 0.0024 0.002 0.0012 0.0005 0.0014 0.0017 0.0011 0.0011 0.0008 0.0006 0.0003 0.0003 0.0014 0.0021 0.0024 0.0009 0.0007 0.0034
Peroxisomes 0.0912 0.0779 0.0964 0.0985 0.0916 0.0671 0.1253 0.069 0.0797 0.09 0.0916 0.0991 0.0811 0.0496 0.0528 0.0181 0.0741 0.0456
Punctate Nuclear 0.0059 0.0012 0.0054 0.0003 0.0056 0.001 0.0036 0.0005 0.0007 0.0013 0.0013 0.0008 0.0028 0.0016 0.002 0.0007 0.0006 0.0078
Vacuole 0.0099 0.0094 0.0045 0.0026 0.0054 0.0076 0.0048 0.0174 0.0111 0.008 0.0014 0.0037 0.0103 0.0106 0.0065 0.0114 0.0043 0.0088
Vacuole Periphery 0.0031 0.0036 0.0023 0.0017 0.0031 0.0049 0.0024 0.0047 0.0048 0.0064 0.0015 0.0028 0.0062 0.0033 0.003 0.0058 0.0024 0.0042

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 8.5997 5.9135 7.0209 9.1524 4.2884 6.6115 5.6802 4.0355 7.1621 8.933
Translational Efficiency 0.6012 0.7609 0.691 0.566 0.7459 0.8493 0.9214 1.2699 0.8184 0.7529

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1347 939 2215 509 1419 1836 2581 1363 2766 2775 4796 1872

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 637.38 654.87 818.73 863.96 675.40 797.08 813.62 852.57 656.88 748.96 815.98 855.67
Standard Deviation 90.45 85.37 106.84 117.88 74.79 363.44 96.82 114.94 84.94 307.22 101.61 115.86
Intensity Change Log 2 — 0.039055 0.361234 0.438811 — 0.238982 0.268613 0.336076 — 0.145367 0.314325 0.386870

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000795 0.002068 0.009592 0.018573 0.001605 0.000670 0.004733 0.020446 0.001211 0.001143 0.006977 0.019937
Bud Neck 0.022154 0.031397 0.029692 0.019417 0.012325 0.030915 0.013546 0.018449 0.017112 0.031078 0.021003 0.018712
Bud Site 0.007692 0.031654 0.070503 0.088074 0.010493 0.011609 0.040649 0.093541 0.009129 0.018392 0.054437 0.092055
Cell Periphery 0.000635 0.000425 0.000213 0.000337 0.000390 0.000262 0.000201 0.000547 0.000509 0.000317 0.000206 0.000490
Cytoplasm 0.025193 0.039135 0.071587 0.030467 0.019762 0.041124 0.017370 0.039196 0.022407 0.040451 0.042410 0.036823
Cytoplasmic Foci 0.132024 0.159270 0.135971 0.150363 0.146284 0.191934 0.085902 0.116394 0.139340 0.180881 0.109026 0.125630
Eisosomes 0.000312 0.000204 0.000135 0.000224 0.000246 0.000212 0.000103 0.000204 0.000278 0.000210 0.000118 0.000210
Endoplasmic Reticulum 0.000856 0.001075 0.008728 0.002706 0.000826 0.000460 0.000894 0.002046 0.000841 0.000668 0.004512 0.002225
Endosome 0.064881 0.109041 0.053194 0.091717 0.068355 0.103865 0.133105 0.099649 0.066663 0.105617 0.096199 0.097492
Golgi 0.126277 0.112307 0.050103 0.084366 0.150608 0.097508 0.109607 0.107852 0.138759 0.102516 0.082125 0.101466
Lipid Particles 0.020931 0.009101 0.005596 0.003768 0.012269 0.018942 0.002158 0.005496 0.016487 0.015612 0.003746 0.005026
Mitochondria 0.490469 0.346383 0.176060 0.144973 0.479121 0.349272 0.385172 0.239402 0.484647 0.348294 0.288595 0.213726
Mitotic Spindle 0.004397 0.013833 0.155883 0.075082 0.007480 0.011179 0.058181 0.054806 0.005979 0.012077 0.103304 0.060319
None 0.002230 0.000764 0.000941 0.000182 0.000244 0.001144 0.000225 0.000275 0.001211 0.001015 0.000556 0.000250
Nuclear Periphery 0.000311 0.000118 0.002787 0.000545 0.000107 0.000432 0.000269 0.000457 0.000206 0.000326 0.001432 0.000481
Nuclear Periphery Foci 0.000324 0.000290 0.002006 0.002450 0.000149 0.000252 0.000425 0.001087 0.000234 0.000265 0.001155 0.001457
Nucleolus 0.002353 0.002301 0.002819 0.001073 0.000445 0.002760 0.000864 0.001125 0.001374 0.002605 0.001767 0.001111
Nucleus 0.007946 0.008695 0.046734 0.011521 0.002936 0.013277 0.003388 0.005229 0.005376 0.011727 0.023407 0.006940
Peroxisomes 0.070707 0.093619 0.062790 0.164150 0.065422 0.075656 0.077766 0.113141 0.067996 0.081734 0.070849 0.127011
Vacuole 0.009272 0.026002 0.102275 0.101421 0.011564 0.037518 0.051107 0.066120 0.010448 0.033621 0.074739 0.075718
Vacuole Periphery 0.010240 0.012318 0.012390 0.008590 0.009368 0.011008 0.014336 0.014537 0.009793 0.011451 0.013437 0.012920

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.37 -10.32 -5.82 -5.37 -2.86 2.22 -4.77 -9.02 -9.66 -7.43 0.27 -10.93 -10.89 -10.99 -7.33
Bud Neck -2.54 -3.32 0.50 3.01 4.00 -8.24 -0.95 -3.26 4.97 -2.77 -6.85 -3.07 -1.17 5.83 1.70
Bud Site -9.64 -23.02 -12.10 -8.02 -2.48 -0.81 -14.53 -19.72 -19.65 -11.79 -7.84 -26.70 -23.44 -20.42 -9.97
Cell Periphery 2.35 5.97 3.95 1.41 -3.49 1.46 2.18 -1.43 -4.77 -6.02 3.21 5.39 0.42 -3.52 -6.60
Cytoplasm -3.62 -14.18 -2.62 0.97 9.88 -7.21 0.85 -7.20 -0.07 -8.37 -7.59 -11.18 -7.11 0.29 1.98
Cytoplasmic Foci -4.15 0.06 -2.08 1.44 -2.28 -7.90 13.05 5.58 13.84 -7.18 -9.55 9.29 3.46 12.49 -4.76
Eisosomes 3.46 6.19 2.63 -1.02 -5.24 1.58 8.09 2.17 0.61 -9.70 3.64 9.66 3.76 0.05 -10.24
Endoplasmic Reticulum -0.52 -12.10 -6.33 -4.10 8.69 2.28 -0.73 -5.06 -8.04 -5.41 0.98 -11.64 -7.38 -8.01 6.89
Endosome -7.40 3.75 -3.59 2.85 -6.37 -7.83 -14.61 -6.23 1.09 6.76 -10.81 -9.43 -7.46 2.39 -0.10
Golgi 2.02 15.27 6.14 4.22 -4.75 8.59 7.09 6.93 -1.47 0.73 8.00 14.67 8.32 0.98 -4.43
Lipid Particles 5.35 8.23 9.05 3.80 3.15 -3.56 7.79 4.41 8.00 -3.70 0.48 11.30 8.97 8.57 -1.91
Mitochondria 10.05 30.10 25.09 14.06 2.69 11.19 8.56 20.28 10.42 14.34 15.31 25.24 29.94 15.64 9.51
Mitotic Spindle -4.81 -28.94 -9.84 -8.30 9.27 -2.20 -17.30 -12.43 -11.43 0.87 -4.95 -32.82 -16.18 -14.05 9.88
None 2.14 1.84 3.04 5.28 6.74 -5.71 0.11 -0.50 5.59 -0.73 0.51 1.90 2.94 6.98 5.64
Nuclear Periphery 2.70 -6.28 -1.47 -2.60 5.20 -2.42 -3.60 -3.74 -0.29 -1.82 -1.27 -6.64 -3.27 -1.51 4.75
Nuclear Periphery Foci 0.27 -8.96 -1.48 -1.50 -0.17 -2.13 -3.42 -3.14 -2.77 -2.07 -0.60 -9.36 -2.76 -2.69 -0.49
Nucleolus 0.02 -1.39 2.20 1.44 4.49 -4.60 -2.36 -2.36 2.79 -0.70 -2.75 -2.02 0.52 3.08 2.55
Nucleus -0.52 -14.83 -2.17 -1.75 9.85 -7.39 -1.12 -2.93 4.37 -2.01 -5.52 -13.87 -2.58 2.38 10.39
Peroxisomes -3.46 2.07 -7.96 -5.54 -9.08 -2.18 -2.58 -7.32 -5.88 -5.62 -3.62 -0.60 -10.39 -7.72 -10.43
Vacuole -6.88 -29.11 -12.90 -10.74 -1.29 -11.65 -17.27 -15.03 -8.06 -4.41 -13.82 -32.90 -19.82 -13.06 -1.61
Vacuole Periphery -1.62 -1.32 1.74 3.01 2.93 -1.79 -5.06 -3.63 -2.48 0.03 -2.21 -4.55 -2.66 -1.08 0.50
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; required for efficient 5' processing of mitochondrial tRNAs, for respiratory growth and mitochondrial genome maintenance; null mutation results in a decrease in plasma membrane electron transport; localizes to the matrix side of the inner mitochondrial membrane
Localization
Cell Percentages mitochondrion (95%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Rrg8

Rrg8


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rrg8-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available