Standard name
Human Ortholog
Description 5'-methylthioribose-1-phosphate isomerase; catalyzes the isomerization of 5-methylthioribose-1-phosphate to 5-methylthioribulose-1-phosphate in the methionine salvage pathway
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.99 0.98 0.96 0.93 0.83 0.79 0.71 0.64 0.7 0.6 0.61 0.98 0.99 0.98 0.96 0.94 0.95 0.97 0.93 0.93 0.94 0.91 0.92
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0.05 0.21 0.23 0.27 0.35 0.33 0.43 0.45 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.05 0.05 0.06 0.07 0.12 0.08 0.08 0.11 0.1 0 0 0.05 0 0.09 0.07 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 2
Bud 0 0 0 0 1 1 4 4 6 2 5 2 0 1 1 0 0 0 1 2 0 3 6 6
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 2 1 2 3 4 5 2 6 10 8 3 3 2 7 10 4 0 0 0 0 0 0
Cytoplasm 167 272 268 198 310 284 368 304 189 190 184 202 525 550 599 300 345 249 165 252 255 345 466 540
Endoplasmic Reticulum 3 0 1 0 5 1 9 0 6 3 2 4 1 2 1 8 7 6 0 1 3 0 1 5
Endosome 0 0 0 0 1 0 0 0 0 0 0 0 1 3 0 0 0 0 1 1 1 1 4 3
Golgi 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 2
Mitochondria 0 3 2 6 16 71 106 115 105 89 132 151 1 0 0 1 1 2 0 2 1 1 4 5
Nucleus 0 1 2 2 4 4 2 12 5 5 8 9 7 4 1 13 3 6 0 2 1 4 8 1
Nuclear Periphery 1 0 0 0 0 1 0 2 3 0 5 2 0 0 0 0 0 0 0 0 0 0 1 2
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 3 1
Vac/Vac Membrane 0 0 5 11 16 22 35 51 25 22 33 32 7 9 28 10 32 17 0 4 5 5 7 7
Unique Cell Count 170 275 274 206 334 341 467 430 296 271 305 333 534 558 611 311 366 261 171 273 275 368 514 587
Labelled Cell Count 171 277 281 218 355 387 528 493 341 318 379 411 545 572 632 339 399 284 171 273 275 368 514 587


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.7 9.4 8.8 8.0 7.5 6.8 6.3 6.2 5.7 5.7 5.3 5.0 10.9 10.6 9.8 15.6 15.2 13.7 11.1 10.9 11.0
Std Deviation (1e-4) 1.6 2.2 1.8 1.9 1.7 1.7 1.7 1.8 1.5 1.4 1.4 1.4 2.2 2.1 1.7 3.3 3.1 2.9 2.1 2.3 2.2
Intensity Change (Log2) – – – -0.14 -0.23 -0.38 -0.49 -0.51 -0.63 -0.64 -0.75 -0.81 0.3 0.27 0.14 0.82 0.78 0.64 0.33 0.3 0.31

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 2.1 0 0 0 0 0 1.8 0
Cytoplasm -1.1 -2.8 -5.9 -7.2 -9.0 -10.2 -8.8 -10.9 -10.9 0.5 0.8 0.2 -1.0 -2.2 -1.5
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 2.9 7.7 8.2 9.0 10.6 10.1 12.1 12.6 0 0 0 0 0 0
Nucleus 0 0 0 0 1.9 0 0 0 0 0 0 0 2.6 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 2.1 2.0 2.8 3.3 4.8 3.5 3.4 4.4 4.0 0 0 2.0 1.1 3.7 2.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.9651 4.5356 5.0036 4.8314 5.2455 5.4429 3.7929 5.3121 4.9348 4.4069 3.7172 4.5553 3.3448 4.9163 4.465 4.9968 4.8205 4.2213
Actin 0.0755 0.0011 0.0011 0.0078 0.0653 0.0006 0.0222 0.0031 0.0237 0.0532 0.003 0.0102 0.0571 0.0014 0.0146 0.0347 0.0958 0.0167
Bud 0.001 0.0003 0.015 0.0222 0.001 0.0001 0.0009 0.0024 0.0016 0.0099 0.0005 0.0022 0.0026 0.0051 0.0178 0.0066 0.0007 0.0026
Bud Neck 0.0039 0.0003 0.0004 0.0017 0.0012 0.0008 0.0058 0.0021 0.0008 0.0011 0.0004 0.002 0.0025 0.0004 0.0006 0.0013 0.0006 0.0037
Bud Periphery 0.0014 0.0001 0.0022 0.0231 0.0023 0 0.0008 0.0006 0.0011 0.0035 0.0008 0.0028 0.0046 0.0021 0.0044 0.0035 0.0005 0.0013
Bud Site 0.0057 0.0011 0.0011 0.0265 0.0012 0.0001 0.0062 0.0105 0.0027 0.0059 0.0003 0.0024 0.0152 0.0019 0.0058 0.0046 0.0035 0.0023
Cell Periphery 0.0006 0.0001 0.0001 0.0003 0.0002 0 0.0003 0.0002 0.0001 0.0004 0 0 0.0008 0.0001 0.0003 0.0005 0.0001 0.0001
Cytoplasm 0.6384 0.7617 0.7446 0.7509 0.6209 0.8417 0.6848 0.9109 0.858 0.7587 0.7582 0.8785 0.5712 0.9156 0.8881 0.7848 0.7558 0.7934
Cytoplasmic Foci 0.0298 0.0101 0.0044 0.0115 0.0124 0.0123 0.0414 0.0091 0.0172 0.0225 0.0201 0.033 0.037 0.0055 0.0049 0.0117 0.0282 0.0132
Eisosomes 0.0006 0 0.0001 0.0002 0.0005 0 0.0002 0 0.0001 0.0002 0 0 0.0012 0 0.0001 0.0003 0.0002 0.0001
Endoplasmic Reticulum 0.0112 0.0036 0.0036 0.0038 0.005 0.0041 0.007 0.0025 0.0017 0.0047 0.0023 0.0038 0.0312 0.0021 0.0033 0.0366 0.0062 0.0019
Endosome 0.0179 0.0083 0.0041 0.0063 0.0223 0.0108 0.034 0.0018 0.0053 0.0247 0.0206 0.0156 0.04 0.0015 0.0047 0.0204 0.0284 0.0139
Golgi 0.0073 0.0004 0.0002 0.0014 0.0076 0.0003 0.0094 0.0005 0.0018 0.0108 0.024 0.0024 0.0107 0.0003 0.0019 0.0067 0.0309 0.0061
Lipid Particles 0.0041 0.0003 0.0001 0.0038 0.0124 0.0003 0.0232 0.0003 0.0025 0.007 0.0116 0.0009 0.0081 0.0001 0.0005 0.0083 0.0083 0.0029
Mitochondria 0.0034 0.0005 0.0015 0.0025 0.0099 0.0003 0.0088 0.0003 0.0016 0.0074 0.0594 0.0015 0.0151 0.0004 0.0028 0.0022 0.0034 0.0031
None 0.1253 0.1856 0.1935 0.0811 0.1551 0.1053 0.0705 0.0413 0.063 0.0259 0.0782 0.0119 0.1189 0.0377 0.0266 0.0423 0.0091 0.087
Nuclear Periphery 0.015 0.0036 0.0033 0.0062 0.0429 0.0048 0.019 0.0017 0.0014 0.0042 0.0013 0.0051 0.0346 0.002 0.0027 0.014 0.0039 0.01
Nucleolus 0.0032 0.0003 0.0003 0.0066 0.0016 0.0001 0.0005 0.0002 0.0001 0.0009 0 0.0002 0.001 0.0001 0.0004 0.0005 0.0001 0.0017
Nucleus 0.0173 0.0154 0.0201 0.0281 0.0145 0.0116 0.031 0.0087 0.0114 0.0251 0.004 0.0183 0.0177 0.0137 0.0166 0.0067 0.0053 0.0205
Peroxisomes 0.023 0.0006 0.0002 0.004 0.0063 0.0002 0.0125 0.0006 0.0033 0.0242 0.012 0.0027 0.0169 0.0084 0.0003 0.0013 0.0136 0.0036
Punctate Nuclear 0.0134 0.0033 0.0017 0.0092 0.0124 0.0052 0.0104 0.0022 0.0018 0.0029 0.0007 0.0045 0.0044 0.0008 0.0027 0.0086 0.0031 0.0099
Vacuole 0.0014 0.0028 0.002 0.0023 0.0019 0.001 0.0092 0.0009 0.0007 0.0052 0.0019 0.0013 0.0047 0.0008 0.0008 0.003 0.0019 0.005
Vacuole Periphery 0.0005 0.0004 0.0004 0.0005 0.0032 0.0003 0.002 0.0001 0.0001 0.0014 0.0006 0.0005 0.0044 0.0001 0.0003 0.0014 0.0006 0.001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 102.2167 109.3313 102.447 100.4545 104.7495 76.7316 89.3638 81.4178 86.4202 89.7973
Translational Efficiency 1.1291 1.1641 1.1494 1.0043 0.8953 1.4575 1.156 1.1574 1.0271 1.0911

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
77 94 1520 1558 2366 812 186 60 2443 906 1706 1618

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 956.13 1013.94 923.22 955.67 881.44 898.56 1225.70 1142.66 883.79 910.53 956.20 962.60
Standard Deviation 134.91 171.64 124.11 217.82 177.71 209.32 185.12 290.96 177.00 208.72 162.32 223.77
Intensity Change Log 2 — 0.084694 -0.050532 -0.000694 — 0.027752 0.475672 0.374462 — 0.057661 0.225813 0.191442

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000306 0.003028 0.000109 0.002622 0.000134 0.000486 0.000816 0.021830 0.000140 0.000750 0.000186 0.003335
Bud Neck 0.001399 0.010210 0.002613 0.003836 0.002960 0.003262 0.003614 0.003861 0.002911 0.003983 0.002722 0.003837
Bud Site 0.009603 0.005985 0.004000 0.025956 0.005216 0.014739 0.007890 0.014165 0.005354 0.013831 0.004424 0.025519
Cell Periphery 0.000167 0.000194 0.000170 0.000170 0.000100 0.000222 0.000266 0.002398 0.000102 0.000219 0.000181 0.000253
Cytoplasm 0.741519 0.652161 0.670743 0.632378 0.767691 0.717934 0.402831 0.454132 0.766866 0.711110 0.641533 0.625768
Cytoplasmic Foci 0.114330 0.097826 0.028490 0.021774 0.042822 0.085486 0.014352 0.023242 0.045076 0.086767 0.026948 0.021828
Eisosomes 0.000026 0.000056 0.000043 0.000030 0.000015 0.000041 0.000068 0.000266 0.000015 0.000042 0.000046 0.000039
Endoplasmic Reticulum 0.001869 0.002817 0.001033 0.001779 0.001502 0.001614 0.008028 0.007005 0.001514 0.001739 0.001795 0.001972
Endosome 0.003764 0.010986 0.002875 0.008147 0.002128 0.007117 0.005309 0.024136 0.002180 0.007518 0.003141 0.008740
Golgi 0.000613 0.004450 0.000166 0.004174 0.000771 0.003227 0.000214 0.016022 0.000766 0.003354 0.000171 0.004613
Lipid Particles 0.001010 0.004320 0.001075 0.001278 0.000699 0.002656 0.002715 0.001655 0.000709 0.002829 0.001253 0.001292
Mitochondria 0.000426 0.001335 0.000294 0.002967 0.000650 0.003663 0.000417 0.001388 0.000643 0.003421 0.000307 0.002909
Mitotic Spindle 0.005441 0.002227 0.000935 0.030791 0.001818 0.008804 0.002872 0.014645 0.001932 0.008122 0.001147 0.030192
None 0.001622 0.001142 0.005579 0.009517 0.008973 0.004992 0.004199 0.008906 0.008741 0.004592 0.005429 0.009495
Nuclear Periphery 0.000212 0.000466 0.000460 0.000718 0.000344 0.000248 0.001857 0.001522 0.000340 0.000270 0.000612 0.000748
Nuclear Periphery Foci 0.003095 0.004331 0.001129 0.003233 0.000831 0.002228 0.007912 0.002004 0.000902 0.002447 0.001868 0.003188
Nucleolus 0.000214 0.000429 0.000465 0.000282 0.000505 0.000862 0.000415 0.001454 0.000496 0.000817 0.000459 0.000325
Nucleus 0.056002 0.098190 0.212598 0.118303 0.132355 0.071311 0.361745 0.277726 0.129948 0.074100 0.228859 0.124215
Peroxisomes 0.000524 0.005167 0.000472 0.001576 0.000291 0.001659 0.000333 0.000834 0.000299 0.002023 0.000457 0.001549
Vacuole 0.056658 0.093753 0.066453 0.126656 0.029504 0.067129 0.173857 0.122363 0.030360 0.069892 0.078163 0.126497
Vacuole Periphery 0.001200 0.000927 0.000298 0.003812 0.000691 0.002320 0.000290 0.000446 0.000707 0.002175 0.000297 0.003687

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.96 2.44 -1.97 0.35 -2.33 -3.54 -8.90 -1.10 -1.03 -0.97 -2.20 -2.12 -2.52 -1.59 -2.43
Bud Neck -1.01 -2.47 -4.92 0.72 -1.45 -0.59 -1.96 -1.93 -1.51 -0.01 -1.02 0.15 -1.49 0.31 -1.30
Bud Site 1.67 2.39 -2.58 -5.59 -6.61 -5.29 -1.80 -1.93 1.84 -0.48 -5.18 0.97 -6.30 -1.56 -6.51
Cell Periphery -0.10 0.17 0.84 1.01 1.41 -3.41 -7.18 -1.60 -1.32 -1.24 -3.57 -4.65 -3.23 1.33 0.50
Cytoplasm 2.73 3.15 7.66 3.24 11.09 6.09 23.97 11.58 9.68 0.12 6.99 17.57 26.86 14.09 8.58
Cytoplasmic Foci 1.26 6.00 6.78 5.95 6.93 -8.99 14.86 6.20 11.38 -0.35 -9.05 9.71 15.16 16.44 6.35
Eisosomes -1.95 -2.64 -0.80 1.75 3.16 -7.49 -9.31 -1.93 -1.44 -0.90 -7.94 -10.35 -7.61 1.57 2.83
Endoplasmic Reticulum -0.93 1.51 0.53 1.61 -3.58 -0.19 -6.93 -3.54 -3.40 0.44 -0.51 -0.76 -1.33 -0.33 -0.67
Endosome -2.38 1.32 -0.61 2.12 -1.87 -4.77 -4.58 -1.03 -0.15 -0.64 -5.38 -3.25 -3.09 2.30 -1.86
Golgi -1.23 2.88 -2.17 0.72 -3.05 -2.12 1.74 -0.85 -0.27 -0.99 -2.35 1.94 -1.82 1.06 -3.20
Lipid Particles -1.82 -0.03 -1.56 1.62 -2.18 -3.45 -7.77 -4.19 0.69 0.75 -3.90 -4.38 -6.64 2.46 -1.45
Mitochondria -0.92 0.45 -1.62 -0.44 -1.94 -1.90 2.83 -0.35 1.80 -1.35 -1.94 3.57 -1.36 1.15 -1.95
Mitotic Spindle 0.67 0.94 -3.05 -6.80 -7.96 -3.15 -1.72 -2.01 -1.42 -1.52 -3.10 0.16 -7.74 -3.80 -7.82
None 0.39 -3.99 -5.20 -5.78 -0.81 3.35 3.19 1.72 -0.54 -0.44 3.68 3.18 2.28 -1.66 -0.91
Nuclear Periphery -2.96 -5.15 -12.39 -5.77 -11.10 0.44 -15.05 -6.37 -6.45 -0.88 0.06 -6.67 -12.49 -12.58 -8.54
Nuclear Periphery Foci -0.94 3.47 0.74 1.56 -6.10 -4.05 -9.38 -2.09 -1.10 1.61 -4.66 -6.03 -7.94 -0.66 -3.75
Nucleolus -1.59 -2.46 -0.55 1.52 2.74 -1.04 2.01 -0.63 0.31 -1.20 -1.03 0.61 2.96 1.87 2.56
Nucleus -2.69 -14.03 -8.49 -2.52 10.04 13.25 -11.60 -4.76 -6.54 0.85 12.07 -15.52 -4.16 -14.45 11.25
Peroxisomes -1.04 0.38 -1.11 0.95 -1.25 -4.43 0.59 -0.57 3.82 -0.77 -3.44 -0.82 -2.14 1.99 -1.34
Vacuole -2.89 -1.27 -11.82 -6.91 -19.74 -10.13 -12.89 -6.46 -4.87 -0.08 -11.10 -15.76 -28.80 -16.86 -17.04
Vacuole Periphery 0.50 1.36 -0.65 -1.42 -2.87 -1.82 3.96 3.33 2.44 -0.33 -1.80 3.46 -1.92 0.39 -2.89
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description 5'-methylthioribose-1-phosphate isomerase; catalyzes the isomerization of 5-methylthioribose-1-phosphate to 5-methylthioribulose-1-phosphate in the methionine salvage pathway
Localization
Cell Percentages cytoplasm (95%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Mri1

Mri1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mri1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available