ORF
Human Ortholog
Description Putative pyridoxine 4-dehydrogenase; differentially expressed during alcoholic fermentation; expression activated by transcription factor YRM1/YOR172W; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.06 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.96 0.97 – 0.96 0.98 0.98 0.94 0.89 0.79 0.85 0.66 0.75 1.0 1.0 1.0 0.97 0.96 0.99 0.8 0.89 0.86 0.87 0.86 0.88
Endoplasmic Reticulum 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0 0 0 0 0 0 0
Endosome 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 – 0 0 0.07 0.15 0.14 0.41 0.29 0.5 0.34 0 0 0 0 0 0 0.09 0.05 0 0 0 0
Nucleus 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 1
Bud 0 0 – 1 0 0 0 0 3 7 4 6 0 0 0 0 1 0 0 0 0 3 6 13
Bud Neck 3 0 – 2 9 4 1 6 2 4 1 2 1 1 0 0 0 0 0 0 0 0 0 2
Bud Site 1 0 – 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 2 – 0 3 4 0 0 0 0 0 1 3 0 0 7 4 5 2 0 1 1 3 3
Cytoplasm 268 31 – 115 294 248 325 315 190 311 131 195 225 296 263 250 128 160 233 62 42 126 211 300
Endoplasmic Reticulum 0 0 – 0 1 1 0 1 0 0 1 0 0 0 0 15 7 6 2 1 0 1 0 1
Endosome 0 0 – 0 2 0 0 0 0 0 0 0 0 1 0 0 2 0 1 0 0 0 0 0
Golgi 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 2
Mitochondria 9 1 – 3 2 17 51 51 99 107 100 89 0 0 0 3 0 1 27 3 2 3 7 3
Nucleus 1 0 – 3 3 1 2 11 2 5 2 6 1 0 0 0 0 0 1 0 0 0 0 1
Nuclear Periphery 2 0 – 1 0 0 0 0 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 1 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
SpindlePole 0 0 – 0 0 1 0 9 1 3 1 3 0 0 0 0 0 0 3 0 1 2 4 4
Vac/Vac Membrane 2 0 – 1 1 1 1 1 4 10 3 11 0 0 1 9 4 5 5 1 1 0 2 3
Unique Cell Count 279 32 120 301 254 347 353 242 366 200 260 225 297 264 257 133 162 291 70 50 146 245 343
Labelled Cell Count 290 34 126 315 277 380 394 303 448 245 313 230 298 264 284 147 177 291 70 50 146 245 343


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.4 4.5 – 4.2 4.7 4.0 3.8 4.2 3.5 4.0 3.7 4.1 5.0 5.2 5.4 7.0 7.5 7.4 5.9 5.9 6.6
Std Deviation (1e-4) 0.7 0.8 – 1.1 1.4 2.0 1.8 1.5 1.6 1.8 1.8 1.6 4.0 1.4 2.3 1.7 1.9 1.7 5.8 5.8 5.8
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.4588 1.8533 1.0465 1.2708 1.4616 1.0727 -0.0653 0.1594 -0.0469 0.35 -0.9273 0.1558 -1.4174 -1.0012 -1.3159 -0.4331 -1.2138 -1.5619
Actin 0.0213 0.001 0.0046 0.04 0.0379 0.0067 0.0411 0.0089 0.0112 0.0448 0.0343 0.0032 0.0218 0.0017 0.0034 0.0317 0.0135 0.0436
Bud 0.0006 0.001 0.0016 0.0111 0.0008 0.0014 0.0027 0.0026 0.0103 0.0018 0.0004 0.0046 0.001 0.0025 0.0003 0.0017 0.0002 0.0006
Bud Neck 0.0013 0.0003 0.0005 0.02 0.0004 0.0006 0.0019 0.0002 0.0022 0.0028 0.0002 0.0005 0.004 0.0002 0.0002 0.0008 0.0006 0.0005
Bud Periphery 0.0014 0.0007 0.0045 0.0069 0.0011 0.0035 0.0026 0.0054 0.0062 0.0053 0.0006 0.0032 0.0012 0.0012 0.0002 0.0019 0.0002 0.001
Bud Site 0.0134 0.0056 0.0043 0.004 0.0009 0.0005 0.0074 0.0185 0.0079 0.0041 0.0015 0.0002 0.0223 0.0216 0.0011 0.013 0.0007 0.0002
Cell Periphery 0.0006 0.0001 0.0003 0.0002 0.0001 0.0001 0.0003 0.0003 0.0002 0.0061 0.0001 0.0001 0.0014 0.0002 0.0001 0.0003 0 0.0001
Cytoplasm 0.1836 0.2449 0.1997 0.227 0.3161 0.2429 0.0971 0.2066 0.1271 0.047 0.1227 0.2407 0.1535 0.2738 0.1483 0.3465 0.1035 0.3317
Cytoplasmic Foci 0.0406 0.0204 0.0155 0.0229 0.013 0.0053 0.0264 0.0089 0.0243 0.0244 0.041 0.0167 0.0281 0.0054 0.0152 0.0202 0.0536 0.0154
Eisosomes 0.0019 0.0001 0.0003 0.0002 0.0004 0.0001 0.0006 0.0001 0.0002 0.0121 0.0003 0.0001 0.0003 0.0001 0.0003 0.0002 0.0007 0.0002
Endoplasmic Reticulum 0.0056 0.001 0.0025 0.0016 0.0037 0.0011 0.0032 0.0008 0.0007 0.0061 0.0006 0.0009 0.0023 0.0023 0.0013 0.0026 0.0006 0.0032
Endosome 0.0323 0.0017 0.0171 0.0308 0.0264 0.0053 0.02 0.0053 0.0065 0.0191 0.0073 0.0052 0.0081 0.0012 0.0173 0.0533 0.0088 0.0146
Golgi 0.0094 0.0004 0.0062 0.0118 0.0112 0.0046 0.0077 0.001 0.0025 0.009 0.0065 0.0022 0.0054 0.0003 0.0121 0.0269 0.0222 0.0227
Lipid Particles 0.0146 0.0002 0.0052 0.0046 0.0123 0.0051 0.0201 0.0015 0.0044 0.0173 0.0331 0.0036 0.0257 0.0003 0.003 0.0015 0.0151 0.0067
Mitochondria 0.0271 0.0002 0.0104 0.0018 0.0052 0.0138 0.0112 0.0017 0.007 0.0225 0.0082 0.0012 0.002 0.0002 0.0026 0.0094 0.0053 0.0271
None 0.5922 0.7165 0.703 0.6061 0.5285 0.6962 0.7163 0.7306 0.7694 0.7465 0.7023 0.6982 0.6709 0.6673 0.7726 0.4801 0.6864 0.5226
Nuclear Periphery 0.0045 0.0004 0.0023 0.0015 0.0231 0.0016 0.0047 0.0005 0.0007 0.0035 0.0008 0.0047 0.0016 0.0007 0.0006 0.0013 0.0003 0.0012
Nucleolus 0.0039 0.0002 0.0008 0.0002 0.0003 0.0007 0.0011 0.0003 0.0004 0.0012 0.0008 0.0005 0.0005 0.0002 0.0001 0.0002 0.0001 0.0004
Nucleus 0.0029 0.0014 0.0017 0.0027 0.0082 0.0042 0.0037 0.0015 0.0019 0.0009 0.0006 0.0017 0.0041 0.0197 0.0008 0.0016 0.0006 0.0013
Peroxisomes 0.028 0.0009 0.0121 0.0036 0.003 0.0017 0.0135 0.0037 0.0107 0.0091 0.032 0.0035 0.0368 0.0001 0.0146 0.0027 0.0857 0.0026
Punctate Nuclear 0.0065 0.0025 0.0023 0.0012 0.004 0.0031 0.0157 0.001 0.0053 0.0094 0.006 0.0083 0.0072 0.0007 0.0011 0.0019 0.0007 0.0023
Vacuole 0.0061 0.0004 0.004 0.0015 0.0021 0.001 0.0018 0.0008 0.0008 0.0045 0.0004 0.0006 0.0013 0.0005 0.0044 0.0014 0.0007 0.0013
Vacuole Periphery 0.0023 0.0001 0.0012 0.0004 0.0013 0.0005 0.0008 0.0001 0.0002 0.0026 0.0002 0.0004 0.0002 0.0001 0.0004 0.0009 0.0002 0.0007

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 21.2602 26.6074 29.6158 27.4568 17.9171 23.3733 36.9913 35.0181 35.0351 31.8179
Translational Efficiency 0.5662 0.6102 0.4815 0.7171 0.8137 0.7345 0.4796 0.6552 0.6031 0.574

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1681 631 2473 1023 1681 1265 221 1154 3362 1896 2694 2177

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 667.64 679.92 767.10 826.63 646.11 700.33 918.25 935.06 656.88 693.54 779.50 884.11
Standard Deviation 79.11 107.16 105.58 340.31 79.98 103.25 140.63 1609.63 80.27 105.01 116.51 1196.14
Intensity Change Log 2 — 0.026295 0.200344 0.308171 — 0.116255 0.507107 0.533279 — 0.071239 0.359357 0.423269

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000153 0.000904 0.000302 0.000390 0.000182 0.000302 0.000393 0.005080 0.000168 0.000502 0.000310 0.002876
Bud Neck 0.020364 0.032317 0.009765 0.007710 0.015762 0.032635 0.001586 0.009213 0.018063 0.032529 0.009094 0.008507
Bud Site 0.006118 0.018498 0.018630 0.024203 0.004506 0.011408 0.002370 0.048814 0.005312 0.013767 0.017296 0.037249
Cell Periphery 0.000156 0.000184 0.000127 0.000214 0.000148 0.000199 0.000202 0.000709 0.000152 0.000194 0.000134 0.000476
Cytoplasm 0.444568* 0.336084* 0.523812* 0.514352* 0.478225* 0.436982* 0.311186* 0.536566* 0.461396* 0.403403* 0.506370* 0.526127*
Cytoplasmic Foci 0.277538* 0.314170* 0.011662 0.042540 0.236924* 0.237971* 0.030525 0.023538 0.257231* 0.263331* 0.013210 0.032467
Eisosomes 0.000212 0.000189 0.000023 0.000063 0.000155 0.000186 0.000084 0.000040 0.000184 0.000187 0.000028 0.000051
Endoplasmic Reticulum 0.000874 0.000901 0.001427 0.002394 0.000862 0.000948 0.004699 0.001317 0.000868 0.000932 0.001696 0.001823
Endosome 0.015387 0.044384 0.001902 0.008138 0.011956 0.022843 0.004881 0.010727 0.013671 0.030012 0.002146 0.009511
Golgi 0.004638 0.011540 0.000862 0.001830 0.002960 0.003413 0.000196 0.005171 0.003799 0.006118 0.000808 0.003601
Lipid Particles 0.013840 0.012354 0.000666 0.001596 0.009839 0.008608 0.002752 0.000860 0.011839 0.009855 0.000837 0.001206
Mitochondria 0.009707 0.024493 0.000931 0.004589 0.010857 0.008763 0.000434 0.003590 0.010282 0.013998 0.000890 0.004059
Mitotic Spindle 0.001889 0.007476 0.007889 0.038820 0.002054 0.003752 0.001203 0.041942 0.001972 0.004991 0.007340 0.040475
None 0.003653 0.004500 0.003321 0.004763 0.003320 0.003331 0.007516 0.006853 0.003486 0.003720 0.003666 0.005871
Nuclear Periphery 0.000437 0.000505 0.001645 0.001261 0.000521 0.000463 0.001769 0.000958 0.000479 0.000477 0.001655 0.001100
Nuclear Periphery Foci 0.000260 0.000747 0.000395 0.001337 0.000346 0.000528 0.002263 0.000911 0.000303 0.000601 0.000549 0.001111
Nucleolus 0.001092 0.004388 0.000360 0.001162 0.001711 0.001818 0.000955 0.000845 0.001402 0.002673 0.000409 0.000994
Nucleus 0.142328* 0.091171 0.371063* 0.190865* 0.168992* 0.142652* 0.523848* 0.184356* 0.155660* 0.125519 0.383597* 0.187414*
Peroxisomes 0.009442 0.030629 0.000304 0.003103 0.006792 0.013858 0.000531 0.003524 0.008117 0.019439 0.000322 0.003326
Vacuole 0.046146 0.061026 0.044500 0.145603 0.042166 0.067138 0.102318 0.110267 0.044156 0.065104 0.049243 0.126872
Vacuole Periphery 0.001197 0.003540 0.000412 0.005067 0.001722 0.002203 0.000290 0.004719 0.001460 0.002648 0.000402 0.004882

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.55 -1.48 -6.22 1.75 -0.93 -1.67 -3.90 -2.49 -2.32 -1.90 -3.15 -1.64 -2.79 -1.81 -2.32
Bud Neck -3.47 6.55 8.99 8.51 3.04 -6.28 11.60 6.72 10.41 -5.77 -6.76 7.75 11.15 13.47 2.45
Bud Site -5.57 -4.61 -4.61 0.95 -0.43 -4.91 1.42 -6.95 -4.02 -7.33 -6.91 -5.35 -8.28 -3.03 -2.68
Cell Periphery -1.44 2.68 -0.17 1.28 -2.72 -2.87 -2.13 -2.08 -1.36 -1.47 -3.09 2.51 -2.07 -1.00 -2.64
Cytoplasm 8.45 -3.55 1.30 -6.61 4.26 4.25 13.36 4.43 0.35 -9.97 7.45 0.54 3.99 -3.17 3.23
Cytoplasmic Foci -3.48 47.81 42.90 31.40 -8.44 -0.16 33.85 41.85 36.35 1.17 -0.99 63.58 59.84 46.84 -7.85
Eisosomes 1.28 15.03 11.92 9.60 -12.27 -2.20 5.12 14.66 11.61 6.29 -0.27 20.90 17.70 14.58 -10.83
Endoplasmic Reticulum -0.17 -5.98 -7.00 -7.42 -3.54 -0.27 -8.15 -8.24 -3.39 6.59 -0.29 -10.86 -9.93 -6.33 -0.16
Endosome -7.84 13.56 9.36 11.08 -4.08 -5.24 7.20 7.23 9.13 0.63 -8.72 17.62 11.75 14.13 -4.60
Golgi -4.24 6.29 6.27 7.08 -0.39 -0.80 9.09 2.16 2.55 -2.71 -3.39 7.47 5.80 7.38 -1.54
Lipid Particles 0.75 12.79 11.96 6.91 -9.34 1.15 9.39 13.31 8.20 5.56 1.98 17.90 17.25 10.64 -5.96
Mitochondria -3.66 6.03 4.53 5.91 -1.35 1.00 6.06 5.37 5.15 -3.65 -1.84 8.36 7.06 7.62 -2.10
Mitotic Spindle -2.60 -4.90 -6.31 -4.12 -4.45 -1.43 -0.76 -7.39 -6.43 -6.82 -2.77 -5.37 -9.69 -7.72 -6.81
None -0.80 0.34 -1.32 -0.18 -2.61 -0.02 -2.01 -5.11 -3.50 -0.31 -0.39 -0.31 -4.03 -2.75 -5.18
Nuclear Periphery -0.64 -18.57 -13.86 -10.19 2.68 0.62 -11.67 -12.18 -13.62 4.26 -0.03 -19.93 -18.55 -17.14 4.68
Nuclear Periphery Foci -3.99 -5.70 -9.74 -4.21 -7.49 -1.43 -5.71 -9.38 -4.16 4.39 -3.27 -7.10 -13.42 -6.05 -5.57
Nucleolus -3.49 6.03 1.71 3.80 -2.48 -0.26 2.67 3.74 3.17 1.77 -2.97 6.11 4.14 4.86 -2.33
Nucleus 7.45 -37.69 -10.48 -15.02 20.10 4.15 -16.03 -8.11 -11.09 12.61 6.43 -40.89 -13.16 -17.16 24.93
Peroxisomes -6.90 12.05 8.09 9.67 -1.70 -5.05 8.86 6.31 9.68 -1.52 -8.14 15.00 10.29 13.50 -2.46
Vacuole -3.59 -7.43 -24.77 -21.09 -21.37 -7.59 -9.04 -25.03 -20.74 -3.31 -8.12 -11.54 -35.17 -29.50 -26.66
Vacuole Periphery -5.24 8.64 -1.04 1.75 -2.22 -0.99 4.87 0.28 1.06 -2.91 -3.69 6.93 -0.67 1.68 -3.38
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative pyridoxine 4-dehydrogenase; differentially expressed during alcoholic fermentation; expression activated by transcription factor YRM1/YOR172W; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus
Localization
Cell Percentages cytoplasm (23%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

YPR127W

YPR127W


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ypr127w-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available