| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Type II integral membrane protein; required for beta-1,6 glucan biosynthesis; putative beta-glucan synthase; localizes to ER, plasma membrane, sites of polarized growth and secretory vesicles; functionally redundant with Skn1p; KRE6 has a paralog, SKN1, that arose from the whole genome duplication |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | – | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – | 0 | 0 | – | – | – |
| Bud | – | 1 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – | 0 | 0 | – | – | – |
| Bud Neck | – | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – | 0 | 0 | – | – | – |
| Bud Site | – | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – | – | – | – | – | – |
| Cell Periphery | – | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – | 0 | 0 | – | – | – |
| Cytoplasm | – | 9 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 330 | – | 4 | 0 | – | – | – |
| Endoplasmic Reticulum | – | 1 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 23 | – | 0 | 0 | – | – | – |
| Endosome | – | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 4 | – | 2 | 0 | – | – | – |
| Golgi | – | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 2 | – | 0 | 0 | – | – | – |
| Mitochondria | – | 3 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 9 | – | 0 | 0 | – | – | – |
| Nucleus | – | 1 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 3 | – | 0 | 0 | – | – | – |
| Nuclear Periphery | – | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – | 0 | 0 | – | – | – |
| Nucleolus | – | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – | 0 | 0 | – | – | – |
| Peroxisomes | – | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – | 0 | 0 | – | – | – |
| SpindlePole | – | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 1 | – | 0 | 0 | – | – | – |
| Vac/Vac Membrane | – | 6 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 39 | – | 33 | 7 | – | – | – |
| Unique Cell Count | 19 | 364 | 48 | 10 | ||||||||||||||||||||
| Labelled Cell Count | 21 | 411 | 48 | 10 | ||||||||||||||||||||
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | – | 5.2 | – | – | – | – | – | – | – | – | – | – | – | – | – | 3.8 | 4.3 | 5.1 | – | – | – |
| Std Deviation (1e-4) | – | 1.2 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0.9 | 1.2 | 1.3 | – | – | – |
| Intensity Change (Log2) | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
External localization resources
Images
Protein Concentration and Protein Localization Data
| R1 | R2 | R3 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Concentration | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Actin | – | – | – | – | – | – | 0.2916 | 0.0027 | 0.001 | 0.0001 | 0.0007 | 0.0099 | 0.465 | 0.001 | 0.0003 | 0.0001 | 0.0001 | 0.0005 |
| Bud | – | – | – | – | – | – | 0.0031 | 0.0025 | 0.0044 | 0.007 | 0.0014 | 0.0005 | 0.0012 | 0.0029 | 0.004 | 0.0036 | 0.0014 | 0.0011 |
| Bud Neck | – | – | – | – | – | – | 0.21 | 0.0012 | 0.0062 | 0.0022 | 0.0014 | 0.006 | 0.007 | 0.0046 | 0.0082 | 0.0043 | 0.0029 | 0.0081 |
| Bud Periphery | – | – | – | – | – | – | 0.004 | 0.0045 | 0.0068 | 0.0034 | 0.0028 | 0.0008 | 0.0018 | 0.0043 | 0.0064 | 0.0049 | 0.002 | 0.0021 |
| Bud Site | – | – | – | – | – | – | 0.1041 | 0.0057 | 0.0054 | 0.004 | 0.002 | 0.0008 | 0.003 | 0.0069 | 0.0105 | 0.0111 | 0.0025 | 0.0017 |
| Cell Periphery | – | – | – | – | – | – | 0.0026 | 0.0009 | 0.001 | 0.0008 | 0.0006 | 0.0008 | 0.0003 | 0.0005 | 0.0009 | 0.0007 | 0.0005 | 0.0008 |
| Cytoplasm | – | – | – | – | – | – | 0.0252 | 0.2747 | 0.2687 | 0.1176 | 0.1459 | 0.3155 | 0.0747 | 0.3381 | 0.2869 | 0.1887 | 0.1092 | 0.332 |
| Cytoplasmic Foci | – | – | – | – | – | – | 0.0173 | 0.0366 | 0.0313 | 0.0448 | 0.0826 | 0.0389 | 0.0215 | 0.0505 | 0.0517 | 0.04 | 0.0361 | 0.0374 |
| Eisosomes | – | – | – | – | – | – | 0.0019 | 0.0001 | 0 | 0 | 0.0001 | 0.0017 | 0.0047 | 0 | 0 | 0 | 0 | 0 |
| Endoplasmic Reticulum | – | – | – | – | – | – | 0.0148 | 0.0093 | 0.0089 | 0.0053 | 0.0046 | 0.0045 | 0.0119 | 0.0061 | 0.0075 | 0.0046 | 0.0039 | 0.0059 |
| Endosome | – | – | – | – | – | – | 0.2188 | 0.1128 | 0.1433 | 0.2702 | 0.2549 | 0.1339 | 0.1158 | 0.0918 | 0.1222 | 0.1644 | 0.1663 | 0.095 |
| Golgi | – | – | – | – | – | – | 0.014 | 0.0018 | 0.0053 | 0.0031 | 0.006 | 0.0019 | 0.0417 | 0.002 | 0.0025 | 0.0022 | 0.002 | 0.0009 |
| Lipid Particles | – | – | – | – | – | – | 0.0039 | 0.003 | 0.0028 | 0.0034 | 0.0033 | 0.0012 | 0.0391 | 0.0017 | 0.0016 | 0.0011 | 0.002 | 0.0014 |
| Mitochondria | – | – | – | – | – | – | 0.0141 | 0.0023 | 0.0082 | 0.002 | 0.0468 | 0.001 | 0.0169 | 0.0044 | 0.0081 | 0.0037 | 0.0036 | 0.0012 |
| None | – | – | – | – | – | – | 0.002 | 0.3587 | 0.2204 | 0.1022 | 0.0544 | 0.1183 | 0.021 | 0.3566 | 0.2429 | 0.1684 | 0.1273 | 0.1188 |
| Nuclear Periphery | – | – | – | – | – | – | 0.0171 | 0.005 | 0.0045 | 0.0048 | 0.0031 | 0.0028 | 0.0119 | 0.0051 | 0.0059 | 0.0053 | 0.0057 | 0.0053 |
| Nucleolus | – | – | – | – | – | – | 0.0138 | 0.001 | 0.001 | 0.0015 | 0.001 | 0.0007 | 0.0026 | 0.0017 | 0.0025 | 0.0026 | 0.0023 | 0.0015 |
| Nucleus | – | – | – | – | – | – | 0.0061 | 0.0049 | 0.008 | 0.0064 | 0.0056 | 0.009 | 0.0416 | 0.0098 | 0.0156 | 0.0153 | 0.0125 | 0.0174 |
| Peroxisomes | – | – | – | – | – | – | 0.003 | 0.0004 | 0.0019 | 0.0008 | 0.0044 | 0.0004 | 0.0374 | 0.0009 | 0.0025 | 0.001 | 0.0019 | 0.0006 |
| Punctate Nuclear | – | – | – | – | – | – | 0.0056 | 0.0013 | 0.0005 | 0.0007 | 0.0014 | 0.0022 | 0.0043 | 0.0014 | 0.0019 | 0.0011 | 0.0063 | 0.0028 |
| Vacuole | – | – | – | – | – | – | 0.0154 | 0.1581 | 0.2522 | 0.3873 | 0.3473 | 0.3295 | 0.07 | 0.1007 | 0.1989 | 0.3515 | 0.4729 | 0.3463 |
| Vacuole Periphery | – | – | – | – | – | – | 0.0117 | 0.0124 | 0.0182 | 0.0326 | 0.0298 | 0.0196 | 0.0067 | 0.0091 | 0.019 | 0.0253 | 0.0385 | 0.0192 |
Sequencing Data
| R1 | R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Gene Expression | 190.5324 | 101.693 | 73.4302 | 84.1675 | 115.7453 | 128.9907 | 114.9251 | 96.9389 | 89.263 | 140.9201 |
| Translational Efficiency | 1.0148 | 1.1945 | 0.9012 | 0.7568 | 0.9747 | 1.352 | 0.9429 | 0.7598 | 0.7975 | 0.8253 |
Hit Data
| Dataset | Hit |
|---|---|
| Protein Concentration | – |
| Protein Localization | ✘ |
| Gene Expression | ✔ |
| Translational Efficiency | ✘ |
Micrographs
Cell Count
| R1 | R2 | R1 & R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
| 2043 | 723 | 619 | 231 | 156 | 22 | 110 | 78 | 2199 | 745 | 729 | 309 |
Protein Abundance
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Mean | 781.33 | 695.83 | 838.96 | 796.98 | 724.00 | 719.05 | 943.30 | 901.56 | 777.26 | 696.52 | 854.70 | 823.38 |
| Standard Deviation | 95.34 | 106.61 | 123.77 | 86.91 | 89.91 | 97.29 | 149.35 | 137.94 | 96.09 | 106.42 | 133.29 | 111.87 |
| Intensity Change Log 2 | — | -0.167197 | 0.102670 | 0.028612 | — | -0.009898 | 0.381727 | 0.316434 | — | -0.089400 | 0.243628 | 0.174215 |
Localization Score (DeepLoc)
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Actin | 0.000826 | 0.000359 | 0.000328 | 0.000233 | 0.000413 | 0.000036 | 0.006866 | 0.000522 | 0.000797 | 0.000350 | 0.001314 | 0.000306 |
| Bud Neck | 0.032858 | 0.026922 | 0.008219 | 0.007691 | 0.037675 | 0.057264 | 0.025333 | 0.023097 | 0.033200 | 0.027818 | 0.010801 | 0.011580 |
| Bud Site | 0.022648 | 0.009171 | 0.011275 | 0.006655 | 0.015617 | 0.031301 | 0.060264 | 0.024833 | 0.022150 | 0.009825 | 0.018667 | 0.011243 |
| Cell Periphery | 0.000214 | 0.000176 | 0.000478 | 0.000160 | 0.000293 | 0.001065 | 0.001194 | 0.000301 | 0.000219 | 0.000202 | 0.000586 | 0.000196 |
| Cytoplasm | 0.367448* | 0.318294* | 0.425221* | 0.341643* | 0.212292* | 0.132887* | 0.186246* | 0.405484* | 0.356441* | 0.312819* | 0.389162* | 0.357758* |
| Cytoplasmic Foci | 0.071268 | 0.245498* | 0.047692 | 0.041088 | 0.171370 | 0.066457 | 0.113481 | 0.087511 | 0.078369 | 0.240211* | 0.057619 | 0.052807 |
| Eisosomes | 0.000103 | 0.000254 | 0.000117 | 0.000116 | 0.000354 | 0.000119 | 0.000534 | 0.000113 | 0.000121 | 0.000250 | 0.000180 | 0.000115 |
| Endoplasmic Reticulum | 0.001010 | 0.001593 | 0.000937 | 0.002541 | 0.001532 | 0.002266 | 0.009159 | 0.008321 | 0.001047 | 0.001613 | 0.002178 | 0.004000 |
| Endosome | 0.025078 | 0.062671 | 0.006404 | 0.009950 | 0.096839 | 0.069963 | 0.113188 | 0.030440 | 0.030169 | 0.062887 | 0.022517 | 0.015122 |
| Golgi | 0.003326 | 0.005924 | 0.000119 | 0.000088 | 0.001029 | 0.003010 | 0.011812 | 0.000242 | 0.003163 | 0.005838 | 0.001884 | 0.000127 |
| Lipid Particles | 0.002732 | 0.017159 | 0.001209 | 0.002514 | 0.007354 | 0.004441 | 0.013848 | 0.006263 | 0.003060 | 0.016783 | 0.003116 | 0.003460 |
| Mitochondria | 0.005644 | 0.003231 | 0.000242 | 0.000169 | 0.000727 | 0.001726 | 0.000557 | 0.000246 | 0.005295 | 0.003187 | 0.000290 | 0.000189 |
| Mitotic Spindle | 0.015383 | 0.001908 | 0.004868 | 0.000352 | 0.000128 | 0.000031 | 0.009019 | 0.002636 | 0.014301 | 0.001853 | 0.005494 | 0.000928 |
| None | 0.001356 | 0.002167 | 0.015394 | 0.004496 | 0.000418 | 0.000019 | 0.001991 | 0.001724 | 0.001289 | 0.002103 | 0.013372 | 0.003796 |
| Nuclear Periphery | 0.000940 | 0.000627 | 0.000513 | 0.001106 | 0.000433 | 0.000185 | 0.000762 | 0.003590 | 0.000904 | 0.000614 | 0.000551 | 0.001733 |
| Nuclear Periphery Foci | 0.000415 | 0.001376 | 0.001211 | 0.001562 | 0.000628 | 0.000160 | 0.007936 | 0.011316 | 0.000430 | 0.001340 | 0.002225 | 0.004024 |
| Nucleolus | 0.000705 | 0.001191 | 0.000980 | 0.000627 | 0.000419 | 0.000181 | 0.001764 | 0.000968 | 0.000685 | 0.001161 | 0.001098 | 0.000713 |
| Nucleus | 0.093271 | 0.053516 | 0.174307* | 0.231882* | 0.027316 | 0.009541 | 0.028499 | 0.100078 | 0.088592 | 0.052217 | 0.152306* | 0.198611* |
| Peroxisomes | 0.005376 | 0.010199 | 0.000786 | 0.001374 | 0.008376 | 0.000709 | 0.006201 | 0.001763 | 0.005589 | 0.009919 | 0.001603 | 0.001472 |
| Vacuole | 0.348165* | 0.235339* | 0.299442* | 0.345577* | 0.412850* | 0.583268* | 0.399077* | 0.289994* | 0.352754* | 0.245614* | 0.314476* | 0.331546* |
| Vacuole Periphery | 0.001232 | 0.002424 | 0.000259 | 0.000177 | 0.003936 | 0.035372 | 0.002268 | 0.000558 | 0.001424 | 0.003397 | 0.000562 | 0.000273 |
Localization Changes (T-score)
| R1 | R2 | R1 & R2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
| Actin | 1.10 | 1.06 | 1.13 | -0.03 | -0.26 | 2.06 | -1.98 | -0.70 | -4.26 | 1.93 | 1.15 | -1.19 | 0.87 | -0.76 | 1.67 |
| Bud Neck | 0.97 | 12.50 | 9.80 | 5.70 | -0.77 | -0.74 | 1.64 | 1.48 | 1.22 | 0.09 | 0.83 | 10.94 | 6.89 | 4.34 | -1.01 |
| Bud Site | 4.19 | 3.15 | 4.86 | 1.11 | 1.30 | -0.85 | -2.86 | -0.90 | 0.46 | 2.08 | 3.80 | 0.28 | 2.41 | -0.50 | 1.67 |
| Cell Periphery | -0.55 | -1.20 | -0.66 | -0.21 | 1.03 | -1.41 | -2.09 | -0.25 | 1.38 | 2.04 | -1.03 | -2.19 | -1.48 | -0.41 | 1.79 |
| Cytoplasm | 1.62 | 0.00 | 7.10 | 5.66 | 6.15 | 1.64 | 0.78 | -4.14 | -4.28 | -4.48 | 1.36 | 1.06 | 4.42 | 3.27 | 3.21 |
| Cytoplasmic Foci | -23.93 | 8.46 | 7.41 | 26.05 | 0.89 | 3.18 | 3.39 | 5.18 | -0.40 | 1.77 | -22.33 | 6.52 | 5.72 | 23.40 | 0.59 |
| Eisosomes | -7.43 | -0.98 | -6.99 | 4.30 | -4.99 | 3.49 | -0.40 | 3.69 | 0.04 | 1.38 | -6.45 | -1.16 | -3.83 | 4.66 | 0.17 |
| Endoplasmic Reticulum | -2.99 | -2.47 | -7.68 | -6.35 | -7.00 | -0.84 | -2.78 | -2.72 | -2.39 | 0.03 | -2.91 | -3.39 | -6.37 | -5.58 | -4.00 |
| Endosome | -11.60 | 10.72 | 6.28 | 15.04 | -1.79 | 1.15 | 0.23 | 5.66 | 2.37 | 3.94 | -10.16 | 2.67 | 5.28 | 13.10 | 1.64 |
| Golgi | -2.69 | 3.57 | 3.59 | 4.69 | 0.44 | -0.76 | -0.98 | 4.85 | 1.06 | 1.08 | -2.79 | 0.48 | 3.65 | 4.73 | 1.07 |
| Lipid Particles | -8.76 | 6.69 | -0.65 | 8.64 | -6.60 | 1.10 | -1.71 | 0.41 | -0.93 | 2.14 | -8.55 | -0.25 | -2.31 | 7.97 | -1.30 |
| Mitochondria | 0.80 | 4.87 | 4.87 | 4.09 | 0.11 | -1.47 | 0.72 | 2.63 | 2.18 | 0.93 | 0.65 | 4.85 | 4.90 | 4.13 | 0.71 |
| Mitotic Spindle | 5.31 | 2.62 | 6.39 | 1.21 | 2.95 | 2.56 | -2.10 | -1.57 | -1.62 | 1.33 | 5.23 | 1.99 | 5.61 | 0.30 | 2.94 |
| None | -0.88 | -3.12 | -3.32 | -0.74 | 2.27 | 2.18 | -1.29 | -2.97 | -4.40 | 0.25 | -0.89 | -3.19 | -3.49 | -0.54 | 2.36 |
| Nuclear Periphery | 5.92 | 5.99 | -2.34 | -6.03 | -5.43 | 1.61 | -2.45 | -1.79 | -1.95 | -1.38 | 5.70 | 4.58 | -1.98 | -3.41 | -2.80 |
| Nuclear Periphery Foci | -2.35 | -7.33 | -5.05 | -1.53 | -1.25 | 2.23 | -4.70 | -2.99 | -3.10 | -1.17 | -2.29 | -7.63 | -4.03 | -3.06 | -2.01 |
| Nucleolus | -1.92 | 0.60 | 1.11 | 2.37 | 0.15 | 2.76 | -1.48 | -1.91 | -2.63 | 0.65 | -1.96 | -0.19 | 0.20 | 1.84 | 0.29 |
| Nucleus | 9.47 | -6.70 | -9.97 | -12.44 | -6.23 | 3.25 | -1.16 | -4.58 | -5.71 | -3.47 | 9.04 | -5.85 | -9.64 | -12.33 | -6.02 |
| Peroxisomes | -3.97 | 7.31 | 4.98 | 6.29 | -1.90 | 4.77 | 1.32 | 4.12 | -2.58 | 3.56 | -3.70 | 6.25 | 5.86 | 6.27 | -0.05 |
| Vacuole | 14.69 | -1.84 | -2.04 | -9.15 | -0.67 | -2.33 | -0.18 | 2.80 | 3.65 | 2.67 | 13.88 | -1.85 | -0.51 | -8.25 | 0.75 |
| Vacuole Periphery | -5.23 | 3.63 | 3.95 | 10.28 | 1.84 | -1.29 | 1.45 | 2.50 | 1.43 | 2.51 | -2.82 | 3.05 | 4.27 | 3.98 | 2.33 |
| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Type II integral membrane protein; required for beta-1,6 glucan biosynthesis; putative beta-glucan synthase; localizes to ER, plasma membrane, sites of polarized growth and secretory vesicles; functionally redundant with Skn1p; KRE6 has a paralog, SKN1, that arose from the whole genome duplication |
| Localization | |
| Cell Percentages | vacuole (16%), ER (4%), mixed (50%) |
| Cell Cycle Regulation | No |
| Subcompartmental Group | N/A |
Kre6
Kre6
Nearest neighbours ( genes)
correlation threshold
0.80
Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)
Endocytosis
| Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
|---|---|---|---|---|
| 37℃ | ||||
| RT |
Cell Cycle Omics
CYCLoPs (Kre6-GFP)
| Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
|---|
| Gene | Images |
|---|
| Gene | Images |
|---|
Images are not yet available
Images are not yet available
