Standard name
Human Ortholog
Description Adapter that links synaptojanins to the cortical actin cytoskeleton; the synaptojanins are Inp52p and Inp53p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.43 0.23 0.55 0.57 0.55 0.31 0.24 – 0.18 0.23 0.13 0.18 0.57 0.55 0.53 0.37 0.43 0.39 0.65 0.5 0.52 0.62 0.47 0.58
Bud 0.14 0.15 0.08 0.19 0.24 0.1 0.16 – 0.11 0.16 0.14 0.09 0.17 0.13 0.09 0.12 0.11 0.11 0.05 0 0.05 0 0.1 0.1
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.08 0.07 0
Bud Site 0.07 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.11 0 0 0 0 – 0 0 0 0.06 0.09 0.06 0.13 0.1 0.08 0.09 0 0 0 0 0 0
Cytoplasm 0.12 0.08 0.17 0.13 0.16 0.14 0.14 – 0.13 0.1 0.09 0.13 0.19 0.21 0.21 0.18 0.22 0.23 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0.08 0.09 0.07 0.08 0.06 – 0 0 0.07 0.08 0.11 0 0.06 0.05 0 0.06 0 0 0 0 0 0
Endosome 0.05 0.07 0 0 0 0.06 0.11 – 0 0.07 0 0 0 0.06 0 0.09 0.07 0 0 0.14 0.06 0 0.15 0.1
Golgi 0.13 0.07 0.28 0.07 0.12 0.1 0.05 – 0.06 0 0 0.06 0.21 0.23 0.31 0.08 0.11 0.14 0.06 0.05 0.06 0.05 0 0
Mitochondria 0.57 0.59 0.12 0.27 0.09 0.39 0.45 – 0.72 0.58 0.8 0.69 0.08 0 0 0.09 0.05 0.06 0 0.11 0.07 0 0.06 0.06
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.21 0.06 0.11 0.18 0.23 0.21 0.14 – 0.07 0.08 0 0 0.11 0.22 0.11 0.1 0.06 0.12 0.08 0.06 0.12 0.07 0.06 0
SpindlePole 0 0 0 0 0.11 0.06 0.08 – 0 0.1 0 0 0 0.05 0 0.24 0.15 0.22 0 0 0 0 0 0
Vac/Vac Membrane 0 0.08 0.05 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 122 31 86 77 123 59 69 – 42 51 31 46 30 87 89 125 138 132 209 111 113 36 61 98
Bud 40 20 13 26 54 19 45 – 26 35 34 22 9 21 15 39 34 36 15 5 10 2 12 17
Bud Neck 0 0 1 1 1 0 1 – 0 2 0 0 0 0 0 3 6 1 5 3 11 4 9 4
Bud Site 20 2 1 6 8 4 12 – 8 9 3 6 2 2 0 1 8 1 – – – – – –
Cell Periphery 2 3 17 4 9 1 5 – 0 5 2 16 5 10 21 35 24 32 0 1 0 0 0 0
Cytoplasm 34 11 26 18 35 27 41 – 30 22 21 32 10 33 35 62 70 79 11 5 9 0 3 2
Endoplasmic Reticulum 5 5 12 12 15 15 18 – 8 7 18 21 6 7 10 16 12 20 2 1 1 0 1 1
Endosome 14 9 6 2 9 12 33 – 6 15 1 7 2 9 5 31 23 13 14 31 12 2 19 16
Golgi 36 10 43 10 27 19 13 – 14 3 3 14 11 36 52 28 36 47 19 10 13 3 1 5
Mitochondria 164 79 19 37 20 76 130 – 171 126 194 176 4 7 6 30 17 22 8 23 14 2 7 10
Nucleus 2 0 0 0 1 4 3 – 4 1 0 1 0 1 1 2 4 3 0 0 0 0 0 0
Nuclear Periphery 2 1 0 0 1 1 1 – 0 0 0 5 1 0 0 0 0 0 1 3 0 0 0 0
Nucleolus 1 4 0 1 1 0 3 – 1 2 2 3 0 0 0 3 1 0 0 0 0 0 0 0
Peroxisomes 59 8 17 25 51 41 41 – 17 17 8 11 6 35 19 35 20 40 27 12 25 4 7 7
SpindlePole 7 2 6 2 25 12 23 – 10 22 7 4 1 8 5 80 49 76 4 4 1 0 1 1
Vac/Vac Membrane 3 11 8 1 4 1 4 – 0 0 1 2 0 0 0 17 10 11 0 3 1 0 1 1
Unique Cell Count 287 135 156 136 224 193 287 237 218 242 254 53 158 167 337 318 342 322 221 216 58 132 169
Labelled Cell Count 511 196 255 222 384 291 442 337 317 325 366 87 256 258 507 452 513 322 221 216 58 132 169


Actin

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.6 8.7 8.6 7.7 8.0 6.7 6.5 – 5.7 5.8 5.1 5.6 8.9 9.2 8.5 9.2 8.7 8.7 7.5 8.8 8.8
Std Deviation (1e-4) 1.5 2.0 1.7 1.3 1.9 1.4 1.4 – 1.2 1.4 1.2 1.3 1.5 1.6 1.6 5.5 1.4 1.4 0.9 1.4 1.5
Intensity Change (Log2) – – – -0.16 -0.11 -0.36 -0.4 – -0.59 -0.56 -0.75 -0.62 0.05 0.1 -0.01 0.1 0.02 0.02 -0.2 0.04 0.04

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0.3 0 -4.6 -6.6 – -7.7 -6.3 -9.0 -7.8 0.2 0 -0.3 -3.8 -2.4 -3.4
Bud 2.7 4.0 0.5 2.2 – 0.9 2.2 1.7 0.1 1.8 1.4 0.2 1.1 0.8 0.8
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery -2.6 -2.6 -4.4 -4.2 – -5.2 -3.5 -4.6 -1.7 -0.3 -1.4 0.5 -0.2 -1.2 -0.5
Cytoplasm -0.8 -0.3 -0.7 -0.7 – -1.1 -1.9 -2.4 -1.1 0.4 1.0 1.0 0.5 1.4 1.6
Endoplasmic Reticulum 0.4 -0.4 0 -0.6 – -1.9 -1.9 -0.1 0.2 0 -1.2 -0.6 -1.3 -1.8 -0.8
Endosome 0 0.1 1.0 2.7 – 0 1.3 0 0 0 0.8 -0.4 2.1 1.4 0
Golgi -4.5 -3.8 -4.3 -7.0 – -6.0 -7.6 -8.0 -6.3 -1.0 -1.0 0.7 -5.7 -4.5 -3.7
Mitochondria 3.3 -1.0 5.7 7.0 – 11.6 8.9 13.3 11.2 -0.9 -2.5 -2.9 -1.1 -2.6 -2.2
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 1.8 3.0 2.6 1.0 – -1.3 -1.0 -3.0 -2.6 0.1 2.7 0.1 -0.2 -1.8 0.3
SpindlePole 0 2.6 1.0 1.7 – 0.2 2.3 -0.5 0 0 0.5 -0.4 5.4 3.7 5.1
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 0 -1.1 -1.0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.9187 2.8324 2.8842 2.5431 2.4146 3.026 4.0785 3.2078 3.3662 3.2795 3.3239 3.5107 4.0564 3.0539 3.191 3.1134 3.1737 3.2548
Actin 0.6503 0.531 0.7404 0.6937 0.839 0.7566 0.7123 0.631 0.7944 0.7222 0.8727 0.7606 0.7554 0.6827 0.7841 0.6553 0.6342 0.7467
Bud 0.0015 0.0123 0.0321 0.0221 0.0055 0.0019 0.0022 0.011 0.0186 0.0254 0.0135 0.0019 0.0017 0.014 0.0395 0.0522 0.0094 0.0012
Bud Neck 0.0046 0.0024 0.0017 0.0008 0.0064 0.0771 0.0037 0.0031 0.0056 0.0013 0.0152 0.085 0.0042 0.0061 0.0058 0.0023 0.0059 0.1184
Bud Periphery 0.0017 0.0127 0.0531 0.0664 0.0128 0.003 0.0034 0.0142 0.0248 0.0539 0.0291 0.0029 0.0017 0.0091 0.0444 0.0705 0.0081 0.002
Bud Site 0.0131 0.1238 0.0258 0.0058 0.0052 0.0026 0.0153 0.1173 0.0322 0.0079 0.0058 0.0038 0.0162 0.0931 0.0244 0.0489 0.0328 0.0035
Cell Periphery 0.0003 0.0009 0.0011 0.0005 0.0008 0.0002 0.0003 0.0017 0.0004 0.0005 0.0004 0.0003 0.0004 0.0008 0.0005 0.0015 0.0008 0.0004
Cytoplasm 0.0044 0.0612 0.0177 0.0068 0.0193 0.0036 0.0051 0.0377 0.0037 0.003 0.0013 0.0065 0.0125 0.0497 0.0205 0.0097 0.0367 0.0037
Cytoplasmic Foci 0.0603 0.078 0.0241 0.0355 0.0104 0.0269 0.0421 0.0393 0.02 0.0152 0.0177 0.0291 0.0401 0.0529 0.021 0.0296 0.0666 0.0344
Eisosomes 0.0006 0.0004 0.0006 0.0005 0.0005 0.0007 0.0007 0.0013 0.0004 0.0003 0.0004 0.0006 0.0018 0.0005 0.0003 0.001 0.0005 0.0006
Endoplasmic Reticulum 0.0014 0.0008 0.0005 0.0022 0.0002 0.0002 0.0011 0.0011 0.0005 0.0004 0.0011 0.0002 0.0034 0.0007 0.0004 0.0025 0.0045 0.001
Endosome 0.0362 0.02 0.0055 0.0299 0.0073 0.0145 0.0268 0.0074 0.0081 0.0222 0.0116 0.0052 0.0192 0.012 0.0034 0.0511 0.0584 0.0069
Golgi 0.049 0.0345 0.0143 0.0412 0.0215 0.0342 0.0631 0.0334 0.0127 0.0326 0.0049 0.016 0.0247 0.0121 0.0101 0.0147 0.0552 0.0126
Lipid Particles 0.0199 0.0027 0.0039 0.0124 0.01 0.0034 0.0067 0.0019 0.0021 0.0016 0.0039 0.004 0.0098 0.0013 0.0017 0.0029 0.004 0.005
Mitochondria 0.0154 0.0104 0.0167 0.0219 0.0209 0.0109 0.0133 0.0051 0.0061 0.022 0.0039 0.0053 0.0172 0.0037 0.0086 0.0113 0.0094 0.0031
None 0.0029 0.0176 0.0035 0.0096 0.0025 0.005 0.0279 0.0327 0.0106 0.0004 0.0006 0.006 0.0256 0.0043 0.0068 0.0024 0.0195 0.0121
Nuclear Periphery 0.0011 0.0003 0.0002 0.0031 0.0005 0.0013 0.0028 0.0005 0.0004 0.0002 0.0039 0.0009 0.0174 0.0003 0.0002 0.0011 0.0024 0.0014
Nucleolus 0.003 0.0002 0.0001 0.0003 0.0001 0.0001 0.0005 0.0005 0.0003 0.0001 0.0006 0.0002 0.0016 0.0003 0.0001 0.0006 0.0013 0.0001
Nucleus 0.002 0.0005 0.0002 0.0004 0.0001 0.0002 0.0008 0.0011 0.0003 0.0001 0.0016 0.0003 0.0079 0.0012 0.0002 0.0005 0.0044 0.0002
Peroxisomes 0.1228 0.0874 0.0567 0.0429 0.0341 0.056 0.0679 0.0558 0.0563 0.0891 0.0074 0.0656 0.0318 0.053 0.027 0.0355 0.0351 0.0449
Punctate Nuclear 0.0071 0.0011 0.001 0.0016 0.0027 0.0008 0.0026 0.0028 0.0014 0.0002 0.0028 0.0053 0.0044 0.0005 0.0003 0.0007 0.0071 0.0004
Vacuole 0.0019 0.0015 0.0005 0.0014 0.0002 0.0004 0.0008 0.0008 0.0007 0.0009 0.001 0.0001 0.0013 0.0015 0.0005 0.0047 0.0031 0.0007
Vacuole Periphery 0.0005 0.0004 0.0002 0.0011 0.0002 0.0002 0.0007 0.0002 0.0002 0.0006 0.0006 0.0001 0.0017 0.0003 0.0002 0.0011 0.0008 0.0007

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 10.199 10.8268 20.2963 17.9249 19.0087 20.3867 19.5893 18.0823 17.4567 20.3336
Translational Efficiency 1.7678 1.6791 0.8934 1.1317 1.0416 0.9628 1.0148 1.2834 1.1378 0.9514

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1056 634 167 437 1142 1585 59 559 2198 2219 226 996

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 749.36 866.38 1053.89 938.56 831.46 855.53 1077.03 896.13 792.02 858.63 1059.93 914.75
Standard Deviation 628.11 148.04 152.46 161.65 119.93 142.20 184.90 138.63 445.76 143.97 161.88 150.65
Intensity Change Log 2 — 0.209341 0.491993 0.324790 — 0.041172 0.373340 0.108061 — 0.123337 0.430803 0.214863

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.439151 0.486798 0.321912 0.342179 0.565416 0.494610 0.294318 0.219121 0.504754 0.492378 0.314708 0.273113
Bud Neck 0.010900 0.006071 0.033956 0.027673 0.004108 0.007682 0.003158 0.032077 0.007371 0.007222 0.025916 0.030145
Bud Site 0.057722 0.054920 0.194225 0.260982 0.034981 0.053394 0.053679 0.285483 0.045907 0.053830 0.157534 0.274733
Cell Periphery 0.001835 0.001679 0.000741 0.001370 0.000679 0.001019 0.001046 0.000614 0.001234 0.001208 0.000821 0.000945
Cytoplasm 0.040394 0.030869 0.044757 0.126114 0.020571 0.029015 0.082837 0.164409 0.030095 0.029544 0.054699 0.147607
Cytoplasmic Foci 0.078557 0.080921 0.074403 0.037171 0.053665 0.071112 0.146747 0.045461 0.065624 0.073915 0.093289 0.041824
Eisosomes 0.001302 0.000578 0.000664 0.000846 0.000609 0.000698 0.000571 0.000341 0.000942 0.000663 0.000640 0.000563
Endoplasmic Reticulum 0.000443 0.001254 0.003994 0.000912 0.000592 0.000484 0.002137 0.000887 0.000521 0.000704 0.003509 0.000898
Endosome 0.030213 0.063283 0.042685 0.013376 0.034809 0.053767 0.056248 0.012067 0.032601 0.056486 0.046226 0.012641
Golgi 0.048141 0.070510 0.022198 0.007712 0.058040 0.079244 0.033355 0.006553 0.053284 0.076749 0.025111 0.007062
Lipid Particles 0.021581 0.029567 0.009765 0.002394 0.012895 0.015591 0.075436 0.003396 0.017068 0.019584 0.026909 0.002956
Mitochondria 0.021345 0.010588 0.001921 0.005981 0.018666 0.017580 0.001191 0.002304 0.019953 0.015582 0.001730 0.003917
Mitotic Spindle 0.000953 0.004855 0.023678 0.016761 0.002385 0.004350 0.013361 0.019968 0.001697 0.004494 0.020985 0.018561
None 0.002547 0.000994 0.000239 0.000246 0.000328 0.000972 0.000899 0.001475 0.001394 0.000978 0.000411 0.000935
Nuclear Periphery 0.000013 0.000022 0.000282 0.000147 0.000046 0.000029 0.000388 0.000394 0.000031 0.000027 0.000310 0.000286
Nuclear Periphery Foci 0.000108 0.000215 0.001832 0.000563 0.000120 0.000158 0.002600 0.000919 0.000115 0.000174 0.002032 0.000763
Nucleolus 0.000152 0.000127 0.000180 0.000073 0.000096 0.000091 0.001779 0.000242 0.000123 0.000101 0.000597 0.000168
Nucleus 0.009202 0.003584 0.055384 0.013215 0.001075 0.002244 0.075408 0.022671 0.004980 0.002627 0.060612 0.018522
Peroxisomes 0.234079 0.147086 0.104390 0.067096 0.189547 0.163150 0.100169 0.098169 0.210942 0.158560 0.103288 0.084535
Vacuole 0.001007 0.005124 0.062490 0.073336 0.001080 0.004075 0.054066 0.078619 0.001045 0.004375 0.060291 0.076301
Vacuole Periphery 0.000353 0.000956 0.000303 0.001853 0.000292 0.000735 0.000606 0.004832 0.000321 0.000798 0.000382 0.003525

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.46 5.55 10.21 11.22 1.40 4.94 6.19 25.36 21.98 1.74 1.17 9.40 24.65 23.41 3.07
Bud Neck 2.46 -2.20 -2.43 -3.89 1.05 -2.36 0.86 -5.74 -4.75 -6.14 0.10 -2.44 -5.87 -5.99 -0.08
Bud Site 0.38 -5.53 -9.98 -10.08 -0.81 -3.64 -0.93 -14.32 -12.87 -8.42 -1.88 -5.85 -17.24 -16.40 -3.56
Cell Periphery 0.16 4.38 2.94 0.69 -1.32 -2.25 -0.46 2.11 3.58 0.87 0.09 2.50 3.69 1.63 0.23
Cytoplasm 1.61 -2.06 -10.69 -11.49 -6.98 -2.38 -3.44 -16.93 -16.11 -4.06 0.03 -4.33 -19.63 -19.78 -9.39
Cytoplasmic Foci -0.35 0.60 7.78 7.45 4.00 -4.13 -3.49 1.81 5.50 3.80 -2.30 -2.69 6.72 9.05 5.15
Eisosomes 3.46 1.98 3.10 -0.55 -0.09 -2.02 0.63 8.26 10.15 1.57 2.70 1.52 4.75 5.20 0.62
Endoplasmic Reticulum -2.18 -5.14 -5.51 -0.68 3.82 0.54 -2.92 -2.98 -4.82 1.55 -1.19 -5.52 -5.57 -4.33 4.13
Endosome -6.35 -1.51 6.75 10.43 4.50 -5.42 -1.33 8.38 13.79 3.58 -8.50 -1.78 10.74 17.51 5.76
Golgi -4.00 6.06 12.87 13.06 3.34 -4.14 2.47 14.07 19.60 1.97 -6.26 6.71 19.08 23.41 3.85
Lipid Particles -1.52 3.28 6.96 5.89 3.59 -1.18 -2.42 4.81 5.74 2.84 -1.09 -1.27 8.34 8.49 3.53
Mitochondria 3.62 7.30 5.32 2.40 -0.95 0.38 7.88 7.47 8.42 -0.98 2.04 10.07 8.99 7.59 -0.90
Mitotic Spindle -3.52 -3.67 -3.58 -2.75 0.82 -2.01 -1.64 -4.10 -3.54 0.20 -3.83 -3.94 -5.45 -4.47 0.88
None 1.57 2.67 2.48 1.04 -1.21 -1.71 -1.20 -1.65 -0.87 -0.89 0.79 2.13 0.22 -0.42 -1.43
Nuclear Periphery -2.11 -5.47 -7.99 -7.80 -0.01 0.41 -3.88 -5.03 -5.41 -0.95 0.09 -6.33 -7.60 -7.89 -0.93
Nuclear Periphery Foci -1.09 -3.41 -6.03 -4.58 2.37 -0.55 -3.74 -3.36 -3.25 2.37 -1.17 -4.29 -5.58 -5.16 2.93
Nucleolus 0.22 -0.91 0.51 0.56 2.13 0.03 -1.60 -1.48 -1.56 1.46 0.33 -1.75 -1.14 -1.48 1.49
Nucleus 2.19 -4.53 -4.69 -5.84 2.66 -1.74 -3.42 -9.49 -9.21 1.51 1.96 -5.84 -10.12 -10.94 2.76
Peroxisomes 7.76 9.80 18.72 10.09 3.23 2.88 4.76 11.49 10.00 0.82 7.37 10.29 20.72 14.62 2.55
Vacuole -3.51 -6.88 -14.59 -14.22 -5.65 -3.54 -3.66 -15.64 -15.31 -3.21 -4.95 -7.80 -21.32 -20.85 -6.30
Vacuole Periphery -1.99 0.30 -2.03 -0.59 -2.15 -2.81 -1.12 -2.05 -1.75 -1.87 -3.33 -0.58 -2.45 -1.89 -2.39
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Adapter that links synaptojanins to the cortical actin cytoskeleton; the synaptojanins are Inp52p and Inp53p
Localization
Cell Percentages actin (69%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Bsp1

Bsp1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Bsp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available