Standard name
Human Ortholog
Description Subunit of the HDA1 histone deacetylase complex; possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex contains Hda1p homodimer and an Hda2p-Hda3p heterodimer; required for the activity of the complex; relocalizes to the cytosol in response to hypoxia; similar to Hda2p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0.23 0 0 0
Bud Neck 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 – – – – – – – – – – 0 0 0 – – – – – – – – –
Cell Periphery 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0 0 – – – – – – – – – – 0.06 0.13 0.15 – – – 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Endosome 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Golgi 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0.23 0.07 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Nucleus 0.92 0.9 – – – – – – – – – – 0.93 0.86 0.84 – – – 0.91 0.9 0 0.85 0.87 0.87
Nuclear Periphery 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0.06 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0.27 0.06 0.05 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 – – – – – – – – – – 0 1 0 – – – 0 0 0 0 0 0
Bud 0 0 – – – – – – – – – – 0 0 0 – – – 1 0 0 1 0 0
Bud Neck 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 1 1
Bud Site 0 0 – – – – – – – – – – 0 0 0 – – – – – – – – –
Cell Periphery 0 0 – – – – – – – – – – 0 1 0 – – – 0 0 0 0 0 0
Cytoplasm 0 4 – – – – – – – – – – 15 55 79 – – – 0 1 0 1 6 6
Endoplasmic Reticulum 2 0 – – – – – – – – – – 1 0 0 – – – 0 0 0 0 0 0
Endosome 0 0 – – – – – – – – – – 0 0 1 – – – 0 0 0 0 0 0
Golgi 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 33 7 – – – – – – – – – – 1 1 0 – – – 0 1 0 0 1 1
Nucleus 131 88 – – – – – – – – – – 233 376 435 – – – 125 107 0 96 285 285
Nuclear Periphery 0 0 – – – – – – – – – – 1 0 3 – – – 0 0 0 0 0 0
Nucleolus 8 4 – – – – – – – – – – 0 0 2 – – – 5 1 0 1 7 7
Peroxisomes 0 1 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 – – – – – – – – – – 2 8 9 – – – 0 0 0 0 1 1
Vac/Vac Membrane 1 1 – – – – – – – – – – 0 3 3 – – – 3 3 0 6 17 17
Unique Cell Count 142 98 250 435 520 139 119 1 113 330 330
Labelled Cell Count 175 105 253 445 532 139 119 1 113 330 330


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.3 6.1 – – – – – – – – – – 7.3 7.5 7.0 – – – 5.8 6.5 6.5
Std Deviation (1e-4) 1.0 1.3 – – – – – – – – – – 1.2 1.5 1.5 – – – 1.1 1.0 1.0
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.9995 1.0769 0.8571 0.3879 0.9876 0.6086 1.5035 1.5598 1.6772 1.1364 1.3104 1.197 0.182 0.3343 -0.0803 0.3648 -0.1162 -0.091
Actin 0.0233 0 0.0306 0.0111 0.0336 0.0019 0.0115 0 0.0001 0 0.0001 0.0008 0.007 0 0.0047 0.0034 0.0145 0.0037
Bud 0.0014 0 0.0002 0.0002 0.0005 0.0001 0.0007 0 0.0002 0.001 0 0 0.0001 0 0.0001 0.0001 0.0002 0
Bud Neck 0.0018 0.0002 0.0015 0.0008 0.0007 0.0041 0.0032 0.0001 0.0001 0.0002 0.0003 0.0008 0.0014 0 0.0005 0.0002 0.0006 0.0008
Bud Periphery 0.002 0 0.0003 0.0002 0.0006 0.0003 0.0017 0 0.0001 0.0002 0.0001 0 0.0002 0 0.0002 0.0001 0.0003 0.0001
Bud Site 0.0056 0.0002 0.0027 0.0009 0.0023 0.0002 0.0029 0.0001 0.0002 0.0001 0.0001 0.0002 0.0009 0 0.0007 0.0003 0.0011 0
Cell Periphery 0.0004 0 0.0001 0.0001 0.0001 0.0001 0.0007 0 0 0 0 0 0.0001 0 0.0001 0.0001 0.0001 0
Cytoplasm 0.0073 0.002 0.0104 0.0014 0.0002 0.0003 0.008 0.002 0.0008 0.0012 0.0009 0.0001 0.0015 0 0.0013 0.0068 0.0011 0.0002
Cytoplasmic Foci 0.0131 0.0002 0.0103 0.019 0.0127 0.0004 0.0251 0.0001 0.0023 0.0023 0.002 0.0044 0.0071 0 0.0048 0.0082 0.004 0.0001
Eisosomes 0.0001 0 0.0004 0.0001 0.0002 0 0.0002 0 0 0 0 0 0.0001 0 0.0002 0.0001 0.0001 0
Endoplasmic Reticulum 0.0025 0.0007 0.0029 0.0004 0.0002 0.0003 0.0031 0.0001 0.0001 0 0.0001 0 0.0005 0 0.001 0.0103 0.0013 0.0001
Endosome 0.0114 0.0007 0.0069 0.0197 0.0249 0.0054 0.0176 0.0002 0.0052 0 0.0313 0.0013 0.0072 0 0.013 0.0173 0.0079 0.0003
Golgi 0.0045 0 0.006 0.0251 0.0331 0.0035 0.006 0 0.0025 0 0.0056 0.0019 0.0018 0 0.0022 0.0026 0.0024 0.0009
Lipid Particles 0.0088 0.0002 0.0027 0.0103 0.0643 0.0025 0.0141 0 0.0052 0 0.0104 0.0034 0.0063 0 0.0043 0.0152 0.0113 0.0003
Mitochondria 0.0176 0.0003 0.006 0.0041 0.0549 0.0024 0.0104 0.0002 0.0017 0.0003 0.0026 0.001 0.0081 0 0.0014 0.0053 0.0013 0.0004
None 0.0096 0.0033 0.0122 0.0024 0.0001 0.0002 0.0037 0.0119 0.0004 0.0009 0.0014 0 0.0018 0 0.0072 0.0078 0.0012 0.0001
Nuclear Periphery 0.0112 0.0066 0.0051 0.0019 0.0023 0.001 0.0202 0.0035 0.0013 0.0005 0.0077 0.0002 0.0018 0.0002 0.0035 0.0136 0.0066 0.0005
Nucleolus 0.0165 0.0161 0.0084 0.0071 0.0138 0.0547 0.0179 0.0141 0.0185 0.0176 0.0351 0.0242 0.0126 0.0077 0.0104 0.005 0.0377 0.0231
Nucleus 0.8234 0.9666 0.8853 0.8798 0.7312 0.9202 0.8135 0.9553 0.9283 0.9545 0.8904 0.9392 0.9256 0.9913 0.9333 0.8583 0.8912 0.965
Peroxisomes 0.0112 0 0.0046 0.0077 0.0186 0.0002 0.0134 0 0.0013 0 0.001 0.005 0.007 0 0.0019 0.0408 0.0019 0.0001
Punctate Nuclear 0.0198 0.0022 0.0025 0.0068 0.0026 0.0014 0.0172 0.012 0.0312 0.0208 0.0081 0.0172 0.0077 0.0006 0.008 0.0014 0.0139 0.0041
Vacuole 0.0062 0.0003 0.0004 0.0006 0.0017 0.0004 0.0041 0.0002 0.0003 0.0001 0.0018 0.0001 0.0007 0 0.0008 0.0021 0.0007 0.0001
Vacuole Periphery 0.0023 0.0002 0.0003 0.0003 0.0012 0.0004 0.0048 0.0001 0.0002 0 0.001 0 0.0004 0 0.0003 0.0009 0.0005 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.7281 8.0193 5.2068 11.2077 11.9945 10.6469 9.5019 12.1423 10.4446 11.655
Translational Efficiency 1.4044 0.848 1.3529 0.6672 0.5927 0.8296 0.8242 0.7512 0.7347 0.5654

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
118 1378 1782 790 1663 1276 1488 181 1781 2654 3270 971

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 656.41 766.96 852.60 950.81 699.65 759.72 895.84 948.66 696.79 763.48 872.28 950.41
Standard Deviation 64.88 124.91 129.63 146.39 98.37 111.60 144.19 137.25 97.11 118.75 138.14 144.73
Intensity Change Log 2 — 0.224554 0.377272 0.534560 — 0.118834 0.356608 0.439258 — 0.170977 0.366647 0.486176

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000052 0.000357 0.000457 0.001161 0.000159 0.000395 0.000584 0.001233 0.000152 0.000375 0.000515 0.001175
Bud Neck 0.001184 0.005472 0.030580 0.027513 0.003158 0.005771 0.019788 0.010569 0.003027 0.005616 0.025669 0.024355
Bud Site 0.000296 0.000879 0.003399 0.014995 0.000564 0.000790 0.002102 0.004929 0.000546 0.000836 0.002809 0.013119
Cell Periphery 0.000243 0.000080 0.000328 0.000159 0.000097 0.000090 0.000168 0.000155 0.000107 0.000085 0.000255 0.000159
Cytoplasm 0.024067 0.004857 0.026136 0.009988 0.011002 0.007814 0.014846 0.011381 0.011867 0.006279 0.020998 0.010247
Cytoplasmic Foci 0.002856 0.000505 0.001455 0.002033 0.001694 0.002487 0.001088 0.000106 0.001771 0.001458 0.001288 0.001674
Eisosomes 0.000021 0.000018 0.000071 0.000029 0.000014 0.000026 0.000028 0.000030 0.000015 0.000022 0.000051 0.000029
Endoplasmic Reticulum 0.001069 0.003905 0.003297 0.005786 0.002632 0.004503 0.003549 0.005086 0.002528 0.004193 0.003412 0.005655
Endosome 0.000208 0.000365 0.000551 0.004938 0.000273 0.002255 0.001285 0.000301 0.000268 0.001274 0.000885 0.004074
Golgi 0.000038 0.000253 0.000090 0.002708 0.000169 0.001083 0.000327 0.000091 0.000160 0.000652 0.000198 0.002220
Lipid Particles 0.000563 0.000289 0.000249 0.000473 0.000856 0.000858 0.000248 0.000173 0.000837 0.000562 0.000248 0.000417
Mitochondria 0.000388 0.001321 0.001680 0.005707 0.001432 0.004265 0.001961 0.001462 0.001363 0.002737 0.001808 0.004916
Mitotic Spindle 0.000025 0.000758 0.007076 0.027661 0.003475 0.005774 0.012247 0.013276 0.003247 0.003170 0.009429 0.024979
None 0.012160 0.006763 0.014992 0.005678 0.009418 0.005794 0.013551 0.011589 0.009599 0.006297 0.014336 0.006780
Nuclear Periphery 0.000533 0.000499 0.001095 0.002275 0.001010 0.001816 0.000848 0.000574 0.000978 0.001132 0.000983 0.001958
Nuclear Periphery Foci 0.000062 0.000278 0.000174 0.001124 0.000261 0.000673 0.000256 0.000101 0.000247 0.000468 0.000211 0.000934
Nucleolus 0.007469 0.014535 0.010402 0.006284 0.013371 0.017522 0.009446 0.006117 0.012980 0.015971 0.009967 0.006253
Nucleus 0.948020* 0.956186* 0.894607* 0.867916* 0.949434* 0.929831* 0.914219* 0.929444* 0.949341* 0.943515* 0.903531* 0.879386*
Peroxisomes 0.000269 0.000462 0.000143 0.000392 0.000368 0.001060 0.000247 0.000301 0.000362 0.000750 0.000191 0.000375
Vacuole 0.000401 0.001612 0.002159 0.009670 0.000441 0.004712 0.002606 0.002943 0.000439 0.003102 0.002362 0.008416
Vacuole Periphery 0.000076 0.000605 0.001060 0.003507 0.000171 0.002483 0.000606 0.000140 0.000165 0.001508 0.000853 0.002879

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -10.15 -12.68 -18.22 -13.84 -10.55 -7.98 -18.15 -7.93 -6.85 -5.20 -8.95 -16.84 -18.30 -15.42 -11.50
Bud Neck -5.88 -20.21 -14.13 -11.65 1.37 -4.13 -16.52 -9.64 -6.54 4.39 -5.15 -24.72 -14.46 -12.45 0.88
Bud Site -1.82 -5.22 -4.89 -4.49 -2.92 -1.42 -6.68 -3.88 -3.64 -2.29 -1.30 -6.24 -5.26 -5.04 -3.49
Cell Periphery 1.31 -0.24 0.70 -5.45 3.92 0.38 -2.19 -2.03 -2.36 -0.38 1.41 -4.79 -2.75 -5.89 3.03
Cytoplasm 2.53 0.39 1.95 -3.29 6.09 1.45 -0.51 0.42 -0.65 0.81 3.45 -2.99 1.46 -2.41 5.27
Cytoplasmic Foci 2.04 1.52 1.77 -0.70 0.90 -0.65 2.43 3.70 4.60 2.53 1.15 2.36 2.66 2.24 0.93
Eisosomes 1.05 -3.98 -7.05 -11.41 1.53 -6.23 -11.43 -6.95 -4.87 -3.69 -5.06 -6.19 -14.13 -11.23 0.15
Endoplasmic Reticulum -8.82 -9.36 -13.96 -7.96 -8.62 -5.87 -8.05 -6.13 -3.98 -4.06 -7.03 -7.83 -12.83 -8.67 -9.27
Endosome -1.57 -3.84 -2.36 -2.17 -1.95 -3.69 -2.23 -3.44 2.90 0.83 -3.79 -3.10 -2.40 -0.81 -1.68
Golgi -2.12 -7.31 -1.60 -1.23 -1.49 -2.61 -0.90 -0.86 2.45 0.29 -2.68 -0.15 -1.41 -0.46 -1.40
Lipid Particles 1.63 1.88 0.98 -1.41 -2.12 0.24 1.56 1.18 2.57 -1.04 1.01 1.78 1.37 1.54 -1.72
Mitochondria -2.78 -8.37 -3.50 -2.53 -2.12 -2.92 -1.62 -1.92 2.04 -0.46 -2.42 -1.72 -2.60 -1.02 -2.05
Mitotic Spindle -1.12 -5.62 -6.13 -5.90 -3.66 -1.30 -3.99 -2.69 -2.36 -1.44 -0.04 -4.61 -5.81 -5.90 -3.71
None 1.53 0.18 2.04 1.65 5.04 2.15 -0.03 1.09 -0.57 1.10 2.41 -0.81 3.44 1.21 5.26
Nuclear Periphery 0.53 -3.68 -9.03 -9.63 -6.02 -2.00 -1.01 -2.55 0.55 -2.12 -0.89 -1.23 -6.68 -4.56 -6.70
Nuclear Periphery Foci -3.77 -2.66 -3.72 -2.46 -2.94 -3.21 -0.39 -1.20 0.16 -1.06 -2.85 0.09 -2.89 -1.40 -2.93
Nucleolus -5.00 -3.36 1.67 8.23 6.59 -3.28 2.87 3.69 5.94 1.60 -2.99 1.95 6.92 11.10 6.41
Nucleus -0.87 4.28 5.23 10.57 2.31 3.80 6.92 4.39 2.61 1.60 1.56 10.79 9.98 9.32 3.52
Peroxisomes -1.44 1.26 -0.22 1.51 -3.07 -2.36 2.10 -0.02 2.15 -1.41 -2.04 2.83 1.33 3.16 -2.53
Vacuole -1.52 -4.24 -7.45 -6.66 -6.56 -4.13 -6.56 -3.76 -2.87 -3.06 -4.40 -8.47 -8.42 -6.68 -6.95
Vacuole Periphery -1.89 -2.45 -1.91 -1.04 -0.62 -3.23 -1.60 -0.47 3.20 1.50 -3.57 -2.59 -1.78 0.52 -0.80
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the HDA1 histone deacetylase complex; possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex contains Hda1p homodimer and an Hda2p-Hda3p heterodimer; required for the activity of the complex; relocalizes to the cytosol in response to hypoxia; similar to Hda2p
Localization
Cell Percentages nucleus (96%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Hda3

Hda3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Hda3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available