Standard name
Human Ortholog
Description (SGD) Protein co-chaperone with a zinc finger motif; essential for protein import into mitochondria; may act with Pam18p to facilitate recognition and folding of imported proteins by Ssc1p (mtHSP70) in the mitochondrial matrix; required for the maintenance of Ssc1p solubility and assists in the functional interaction of Ssc1p with substrate proteins
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.08 0.1 0.05 0.06 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.58 0.33 0.33 0.41 0.28 0.28 0.23 0.24 0.32 0.23 0.27 0.22 0.5 0.52 0.42 0.14 0.09 0.06 0 0 0 0 0 0
Nucleus 0.13 0.17 0.06 0 0 0 0.05 0 0 0 0 0.07 0.08 0.06 0 0.09 0.1 0.11 0.08 0.13 0.07 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.91 0.89 0.91 0.95 0.93 0.93 0.9 0.9 0.9 0.9 0.93 0.88 0.87 0.86 0.83 0.85 0.86 0.88 0.84 0.78 0.83 0.84 0.83 0.77
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0.05
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 1 0 1 1 0 0 0 0 0 1 0 0 2 2 5 4
Bud Neck 0 0 1 0 0 0 1 3 3 1 3 0 0 0 0 1 0 0 0 0 0 1 3 2
Bud Site 0 0 0 0 0 0 1 1 9 4 4 6 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 1 8 5 9 9 13 21 7 12 4 10 15 16 28 22 20 6 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 3 0 0 0 0 0 0
Endosome 0 0 2 1 2 3 6 8 7 6 3 6 1 1 2 1 0 1 2 3 2 1 2 4
Golgi 0 0 0 0 0 0 0 1 0 1 2 0 0 0 0 3 2 1 0 0 1 1 1 3
Mitochondria 203 87 109 110 72 72 105 176 173 134 138 105 104 102 113 61 30 16 1 1 1 1 6 5
Nucleus 46 45 21 6 9 9 22 32 22 21 19 33 16 12 10 39 32 30 29 34 21 3 7 6
Nuclear Periphery 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 2 2 1 0 1 4
Nucleolus 316 236 297 253 237 237 412 650 493 515 465 410 182 170 222 358 279 249 294 215 274 149 310 281
Peroxisomes 0 0 1 2 0 1 4 6 5 5 4 7 3 2 1 0 0 0 1 0 0 1 2 4
SpindlePole 0 0 1 2 3 3 15 13 21 29 22 11 2 1 3 1 0 0 8 5 15 5 16 19
Vac/Vac Membrane 1 1 1 1 1 1 8 6 2 4 2 2 2 2 3 6 5 8 6 10 7 7 12 21
Unique Cell Count 348 264 326 266 254 254 459 721 547 573 502 468 210 197 268 421 323 284 351 277 331 177 375 364
Labelled Cell Count 567 370 441 380 333 335 587 918 743 732 667 591 325 307 382 496 371 315 351 277 331 177 375 364


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 58.5 46.6 50.6 48.0 40.8 40.8 28.9 26.2 23.5 25.2 22.5 22.8 56.1 54.4 56.1 60.7 70.1 62.5 49.4 56.7 62.8
Std Deviation (1e-4) 18.0 12.6 17.8 18.2 15.9 15.9 10.7 9.7 8.7 9.7 8.1 9.7 21.9 22.1 28.0 27.9 27.2 26.4 20.1 20.3 26.0
Intensity Change (Log2) – – – -0.08 -0.31 -0.31 -0.81 -0.95 -1.1 -1.0 -1.17 -1.15 0.15 0.1 0.15 0.26 0.47 0.31 -0.03 0.16 0.31


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.5 0.8 0.8 0.3 0.4 -1.3 -0.4 0 -0.3 2.6 3.0 4.1 1.9 2.3 -0.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.0 -1.3 -1.3 -3.3 -3.0 -0.6 -3.3 -1.8 -3.4 3.7 4.1 2.2 -6.1 -7.5 -8.5
Nucleus -2.4 -1.6 -1.6 -1.0 -1.4 -1.6 -1.9 -1.7 0.3 0.5 -0.2 -1.5 1.4 1.6 1.8
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 1.9 1.0 1.0 -0.6 -0.5 -0.5 -0.6 0.8 -1.6 -1.6 -1.7 -3.0 -2.5 -1.9 -1.4
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 2.9 0 3.2 3.8 3.5 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.3716 7.8441 6.8929 5.6038 5.8376 6.288 9.0375 12.1321 10.2147 9.6342 9.2191 10.0679 11.2907 13.935 12.4113 11.3812 10.7886 12.3949
Actin 0.0179 0 0.036 0.0412 0.0005 0.0005 0.0215 0.0012 0.0046 0.0171 0.0004 0.0002 0.0178 0.0012 0.0001 0.0001 0.0031 0.0037
Bud 0.0004 0.0001 0.0012 0.0006 0.0002 0.0002 0.0004 0.0005 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0 0.0001 0.0003 0.0001
Bud Neck 0.0058 0.0002 0.0021 0.0026 0.0005 0.0011 0.0004 0.0002 0.0007 0.0003 0.0002 0.0004 0.0004 0.0002 0.0001 0.0003 0.0005 0.0005
Bud Periphery 0.0008 0.0002 0.0008 0.0012 0.0007 0.0007 0.0006 0.0006 0.0003 0.0003 0.0002 0.0005 0.0002 0.0002 0.0001 0.0003 0.001 0.0003
Bud Site 0.0019 0.0001 0.0167 0.006 0.0013 0.0003 0.0013 0.0031 0.0008 0.0003 0.0006 0.0001 0.0004 0.0007 0.0001 0.0002 0.0008 0.0002
Cell Periphery 0.001 0.0004 0.0006 0.0005 0.0004 0.0009 0.0003 0.0002 0.0004 0.0001 0.0003 0.0005 0.0003 0.0002 0.0001 0.0002 0.0002 0.0003
Cytoplasm 0.0111 0 0.0139 0.0144 0.0002 0.0004 0.0026 0.0002 0.0012 0.0001 0.0025 0 0.0047 0 0.0001 0.0001 0.0021 0.0002
Cytoplasmic Foci 0.0186 0.0001 0.0086 0.0116 0.003 0.0009 0.004 0.0003 0.005 0.0015 0.021 0.0002 0.0113 0.0056 0.008 0.0002 0.004 0.0018
Eisosomes 0.0004 0 0.0003 0.0006 0.0001 0.0001 0.0002 0 0.0001 0.0002 0.0001 0.0001 0.0001 0 0 0 0.0001 0.0001
Endoplasmic Reticulum 0.0084 0 0.0025 0.0038 0.0002 0.0006 0.0008 0.0001 0.0005 0.0001 0.0006 0.0001 0.0018 0 0 0.0001 0.0036 0.0004
Endosome 0.0224 0.0001 0.0085 0.0141 0.0157 0.0036 0.0102 0.0003 0.002 0.0008 0.0022 0.0003 0.0088 0.0002 0.0006 0.0002 0.0347 0.0032
Golgi 0.0061 0.0001 0.0029 0.0188 0.0046 0.0007 0.0033 0.0003 0.001 0.0031 0.0008 0.0002 0.0014 0.0005 0.0003 0.0001 0.0034 0.0012
Lipid Particles 0.0112 0.0025 0.0049 0.0172 0.0173 0.0158 0.0089 0.0013 0.0053 0.0052 0.0157 0.0071 0.0118 0.0058 0.0054 0.0014 0.0485 0.0079
Mitochondria 0.0021 0.0008 0.0027 0.0256 0.047 0.0043 0.0076 0.0028 0.0012 0.0077 0.0039 0.0041 0.0021 0.0012 0.0003 0.0004 0.0273 0.002
None 0.0142 0 0.0045 0.0041 0.0003 0.0002 0.0039 0 0.0016 0.0002 0.0037 0.0002 0.0104 0.0001 0.0001 0.0001 0.0019 0.0003
Nuclear Periphery 0.0424 0.0163 0.0163 0.0941 0.0282 0.0984 0.0465 0.0175 0.0244 0.0522 0.1904 0.1074 0.0787 0.0282 0.0192 0.1431 0.1218 0.0858
Nucleolus 0.599 0.6235 0.6881 0.4491 0.6238 0.6413 0.7177 0.6888 0.7872 0.7667 0.4719 0.6789 0.659 0.7599 0.8454 0.6565 0.4947 0.6872
Nucleus 0.2136 0.3496 0.1587 0.258 0.2411 0.2072 0.1423 0.2677 0.1534 0.1184 0.2429 0.1793 0.1519 0.1824 0.1071 0.1776 0.2274 0.1857
Peroxisomes 0.0024 0.0001 0.01 0.0146 0.0054 0.0002 0.0016 0.0001 0.0015 0.0014 0.0005 0.0001 0.001 0.0026 0.0033 0.0001 0.0024 0.0008
Punctate Nuclear 0.0143 0.0011 0.0176 0.0146 0.0027 0.0044 0.0185 0.01 0.0056 0.0202 0.0332 0.007 0.031 0.0062 0.0073 0.0122 0.0128 0.0113
Vacuole 0.0036 0.0014 0.002 0.0018 0.0042 0.0035 0.0024 0.0024 0.0015 0.0004 0.002 0.0018 0.0015 0.0008 0.0008 0.0008 0.0024 0.0009
Vacuole Periphery 0.0023 0.0032 0.0011 0.0054 0.0028 0.0148 0.0051 0.0023 0.0018 0.0036 0.0068 0.0114 0.0054 0.0039 0.0014 0.0058 0.0067 0.0062

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 33.6276 20.6669 19.5182 30.8723 43.5996 35.7095 23.2709 25.0018 32.7942 38.5496
Translational Efficiency 2.4971 1.7177 1.8841 1.802 1.8187 2.5381 1.4873 1.8473 1.6589 1.7908

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘


Micrographs

Cell Count

Number of cells analysed for each strain. R1, R2: biological replicates; R1 & R2: both replicates combined.

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1281 1120 2715 205 417 2347 2190 2115 1698 3467 4905 2320

Protein Abundance

Mean and standard deviation of cell GFP intensity, and intensity change (log2) of each mutant relative to wild type.

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 897.13 972.91 1335.18 1459.43 1095.83 1151.32 1395.84 1402.42 945.93 1093.69 1362.26 1407.46
Standard Deviation 206.29 238.45 251.01 337.75 167.76 207.06 320.16 284.51 215.25 233.13 285.57 290.06
Intensity Change Log 2 — 0.116989 0.573645 0.702016 — 0.071265 0.349110 0.355894 — 0.092027 0.454527 0.522035

Localization Score (DeepLoc)

Localization score for each compartment. Values highlighted in green denote significant localization scores (marked * in the plot).

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000739 0.000848 0.000642 0.000963 0.000409 0.000442 0.001082 0.001142 0.000658 0.000573 0.000838 0.001126
Bud Neck 0.002819 0.003716 0.004908 0.012282 0.000883 0.003255 0.005663 0.009664 0.002344 0.003404 0.005245 0.009896
Bud Site 0.000618 0.001714 0.000240 0.003633 0.000116 0.000407 0.000409 0.000890 0.000495 0.000829 0.000315 0.001132
Cell Periphery 0.000124 0.000201 0.000022 0.000107 0.000013 0.000046 0.000070 0.000208 0.000097 0.000096 0.000043 0.000199
Cytoplasm 0.002042 0.005155 0.000197 0.001014 0.000057 0.000347 0.000343 0.001264 0.001554 0.001900 0.000262 0.001242
Cytoplasmic Foci 0.000549 0.000885 0.000160 0.004170 0.000787 0.000197 0.000708 0.000959 0.000607 0.000419 0.000405 0.001243
Eisosomes 0.000045 0.000065 0.000034 0.000054 0.000045 0.000047 0.000045 0.000037 0.000045 0.000053 0.000039 0.000039
Endoplasmic Reticulum 0.003882 0.002420 0.000641 0.000799 0.001163 0.001502 0.000833 0.001416 0.003214 0.001799 0.000727 0.001362
Endosome 0.000568 0.000623 0.000123 0.004660 0.000094 0.000794 0.000119 0.001323 0.000451 0.000739 0.000121 0.001617
Golgi 0.000247 0.000929 0.000155 0.001885 0.000156 0.000159 0.000223 0.000999 0.000225 0.000408 0.000185 0.001077
Lipid Particles 0.000372 0.000117 0.000012 0.000138 0.001963 0.000122 0.000077 0.000294 0.000762 0.000120 0.000041 0.000280
Mitochondria 0.001861 0.002026 0.001787 0.005377 0.000944 0.001529 0.003820 0.005158 0.001636 0.001689 0.002695 0.005177
Mitotic Spindle 0.000525 0.000831 0.001765 0.025891 0.003312 0.002584 0.001919 0.003708 0.001210 0.002018 0.001834 0.005669
None 0.004465 0.007795 0.000740 0.001368 0.000309 0.001547 0.001084 0.002200 0.003444 0.003566 0.000894 0.002126
Nuclear Periphery 0.020297 0.005146 0.013705 0.021124 0.016660 0.007357 0.026226 0.063800 0.019404 0.006643 0.019295 0.060030
Nuclear Periphery Foci 0.007968 0.004370 0.002222 0.005754 0.012878 0.003727 0.005303 0.012604 0.009174 0.003935 0.003598 0.011999
Nucleolus 0.430666* 0.469430* 0.516774* 0.606386* 0.605637* 0.481654* 0.499092* 0.459087* 0.473636* 0.477705* 0.508879* 0.472103*
Nucleus 0.510702* 0.479944* 0.450515* 0.276193* 0.344855* 0.488435* 0.435092* 0.408341* 0.469973* 0.485692* 0.443629* 0.396664*
Peroxisomes 0.001711 0.005120 0.002931 0.010691 0.007258 0.002285 0.004187 0.002506 0.003073 0.003201 0.003492 0.003229
Vacuole 0.003037 0.004112 0.000457 0.005182 0.000473 0.001226 0.002196 0.005025 0.002407 0.002158 0.001233 0.005039
Vacuole Periphery 0.006764 0.004552 0.001970 0.012330 0.001991 0.002339 0.011509 0.019374 0.005592 0.003054 0.006229 0.018751

Localization Changes (T-score)

Change in localization of each mutant relative to its control (e.g. UBP2_WT: ubp2Δ vs wild type). Values highlighted in yellow (increase) or blue (decrease) denote significant changes (marked * in the plot).

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.73 1.62 -2.33 -1.78 -2.79 -1.04 -17.47 -17.10 -19.01 -1.37 1.75 -4.57 -9.58 -14.41 -8.40
Bud Neck -2.26 -7.34 -5.72 -5.39 -4.79 -10.43 -20.02 -17.53 -12.88 -8.52 -4.08 -12.71 -15.47 -13.89 -10.22
Bud Site -2.75 2.02 -3.12 -2.67 -3.28 -3.17 -4.97 -6.57 -4.23 -4.20 -1.71 1.12 -4.25 -3.21 -5.37
Cell Periphery -1.87 5.03 -0.57 1.18 -3.92 -3.78 -7.84 -2.27 -1.89 -1.62 0.03 3.44 -1.34 -1.35 -2.03
Cytoplasm -1.78 2.14 -0.59 1.15 -2.14 -1.85 -4.97 -6.37 -4.30 -5.11 -0.48 1.99 -0.28 0.34 -5.57
Cytoplasmic Foci -0.64 1.25 -2.66 -2.54 -2.90 1.09 0.09 -0.36 -2.66 -0.83 0.88 0.74 -1.87 -3.04 -2.94
Eisosomes -5.04 3.63 -2.67 0.58 -4.79 -0.36 0.26 2.21 4.47 2.99 -2.93 2.49 2.07 6.65 -0.39
Endoplasmic Reticulum 4.04 10.14 8.36 6.60 -1.79 -2.22 2.85 -1.56 0.64 -4.64 5.37 10.18 6.97 3.08 -5.74
Endosome -0.37 4.38 -1.54 -1.52 -1.73 -2.82 -0.93 -3.32 -1.13 -3.25 -1.58 4.64 -2.79 -1.91 -3.65
Golgi -1.28 1.42 -1.76 -0.88 -1.86 0.03 -2.14 -2.59 -2.60 -2.39 -1.02 0.84 -2.75 -1.89 -2.91
Lipid Particles 0.87 1.23 0.37 -1.98 -3.53 0.96 0.99 0.88 -0.82 -1.24 1.21 1.39 0.89 -0.97 -1.62
Mitochondria -0.93 -0.03 -3.74 -3.57 -3.75 -3.37 -17.41 -11.61 -9.24 -3.39 -0.45 -8.88 -10.24 -9.82 -7.05
Mitotic Spindle -0.92 -3.02 -4.07 -4.02 -3.86 0.50 0.78 -0.22 -1.67 -2.61 -1.04 -1.09 -4.90 -4.35 -4.64
None -2.01 4.32 3.19 4.19 -1.86 -2.93 -7.22 -3.96 -1.09 -2.37 -0.16 3.98 1.60 1.92 -2.77
Nuclear Periphery 5.95 2.61 0.29 -2.40 -0.89 2.61 -2.38 -9.22 -15.20 -8.98 6.25 0.13 -10.30 -15.62 -11.43
Nuclear Periphery Foci 2.94 5.25 1.54 -0.47 -1.97 3.69 3.09 0.25 -8.67 -7.19 4.85 5.42 -1.92 -8.79 -9.79
Nucleolus -3.36 -8.49 -6.18 -4.48 -2.61 9.93 8.31 11.78 3.22 4.84 -0.46 -4.13 1.10 1.75 5.57
Nucleus 2.69 5.89 11.32 9.77 8.75 -11.82 -7.24 -5.54 8.47 2.29 -1.95 3.08 7.28 10.60 5.55
Peroxisomes -6.60 -5.10 -6.53 -4.35 -5.77 3.47 2.07 3.23 -1.12 3.09 -0.25 -1.00 -1.04 -1.06 -0.09
Vacuole -1.19 4.32 -2.22 -1.99 -2.75 -2.95 -7.40 -6.77 -5.47 -4.21 0.44 2.52 -4.19 -4.77 -6.13
Vacuole Periphery 1.79 4.35 -1.24 -1.92 -2.70 -0.42 -8.31 -11.45 -12.71 -4.90 2.80 -0.63 -8.62 -12.41 -9.65
Standard name
Human Ortholog
Description (SGD) Protein co-chaperone with a zinc finger motif; essential for protein import into mitochondria; may act with Pam18p to facilitate recognition and folding of imported proteins by Ssc1p (mtHSP70) in the mitochondrial matrix; required for the maintenance of Ssc1p solubility and assists in the functional interaction of Ssc1p with substrate proteins
Localization
Cell Percentages nucleus (32%), nucleolus (12%), mixed (39%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Zim17

Zim17


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)