Standard name
Description Mitochondrial inner membrane half-type ABC transporter; mediates export of peptides generated upon proteolysis of mitochondrial proteins; plays a role in the regulation of cellular resistance to oxidative stress

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0.05 0.05
Bud 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Cytoplasm 0.53 0.37 0.31 0.34 0.24 0.14 0.14 0.1 0.07 0 0 0.77 0.82 0.82 0.38 0.41 0.2 0.23 0.17 0.1 0.15 0.17 0.21
Endoplasmic Reticulum 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Endosome 0.05 0 0.05 0 0.1 0 0 0 0 0 0 0.05 0 0.07 0.19 0.19 0.4 0.05 0.07 0.11 0.08 0.07 0.07
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0 0 0 0 0 0
Mitochondria 0.37 0.62 0.59 0.62 0.58 0.87 0.81 0.86 0.93 0.94 0.93 0.06 0.05 0 0.14 0.12 0.05 0.52 0.54 0.59 0.51 0.47 0.42
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.08 0 0.06 0 0 0 0 0 0 0 0 0 0 0.08 0.2 0 0 0.06 0.05 0.05 0
SpindlePole 0 0 0.07 0 0.07 0 0.08 0.07 0.05 0 0.07 0 0 0 0.06 0.06 0.15 0 0 0 0 0.06 0.06
Vac/Vac Membrane 0.06 0 0 0 0.1 0.07 0 0 0 0 0 0.05 0 0.07 0.24 0.29 0.25 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 9 0 1 0 0 0 0 0 0 0 2 7 2 0 0 1 6 10 11 18 28 31
Bud 2 14 7 10 3 8 22 28 31 13 28 1 1 1 0 0 0 2 6 2 7 17 16
Bud Neck 1 1 2 0 1 0 0 2 1 0 1 3 4 1 0 0 0 1 9 4 8 9 21
Bud Site 1 2 1 0 1 1 13 12 22 8 14 0 0 0 1 0 0
Cell Periphery 2 3 3 0 1 2 5 2 2 5 8 3 0 2 2 1 1 0 2 0 3 5 6
Cytoplasm 94 140 101 68 82 57 87 76 47 16 26 179 191 210 41 49 4 53 73 38 76 103 136
Endoplasmic Reticulum 1 23 2 1 1 3 1 1 2 1 0 2 5 5 3 6 0 3 2 2 5 4 5
Endosome 9 0 16 8 35 11 11 13 0 1 2 12 6 18 21 23 8 11 30 39 38 40 44
Golgi 0 0 1 0 1 0 0 0 0 0 0 2 2 1 1 0 2 3 5 7 6 7 6
Mitochondria 65 237 193 125 193 365 510 676 649 471 642 15 12 1 15 14 1 121 232 219 253 287 274
Nucleus 0 1 0 0 3 4 11 19 5 6 11 1 1 2 5 7 0 0 0 0 1 2 0
Nuclear Periphery 1 1 0 0 5 5 16 17 21 18 27 0 0 0 0 0 0 1 0 1 2 3 4
Nucleolus 0 1 0 1 3 3 17 32 33 9 19 0 0 0 0 0 0 0 1 0 1 3 3
Peroxisomes 5 0 26 9 20 6 15 28 6 2 12 5 0 4 4 10 4 5 5 21 22 31 25
SpindlePole 5 6 24 8 22 8 53 58 34 17 46 6 2 2 7 7 3 8 15 12 21 38 40
Vac/Vac Membrane 10 14 13 3 35 30 28 17 20 12 23 12 8 17 26 35 5 4 18 3 13 17 22
Unique Cell Count 177 382 326 200 335 420 633 789 699 499 689 231 234 256 109 120 20 233 429 372 493 617 654
Labelled Cell Count 196 452 389 234 406 503 789 981 873 579 859 243 239 266 126 152 29 233 429 372 493 617 654


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.1 3.8 3.9 3.9 4.1 3.6 3.5 3.8 3.4 3.7 3.8 5.2 5.3 5.5 5.9 6.8 8.2 5.4 5.6 5.6
Std Deviation (1e-4) 1.0 0.6 1.1 1.3 1.5 1.2 1.2 1.2 1.0 1.1 1.1 1.1 1.0 1.1 1.6 1.9 1.4 1.4 1.7 1.6
Intensity Change (Log2) 0.01 0.08 -0.11 -0.15 -0.02 -0.18 -0.06 -0.03 0.44 0.46 0.52 0.62 0.82 1.09 0.48 0.54 0.53


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin
Bud 0 0
Bud Neck 0 0
Bud Site 0 0
Cell Periphery 0 0
Cyto
Endoplasmic Reticulum 0 0
Endosome 0 0
Golgi 0 0
Mitochondria 0 0
Nuclear Periphery 0 0
Nuc
Nucleolus 0 0
Peroxisomes 0 0
SpindlePole 0 0
Vac
Cortical Patches 0 0
Cytoplasm 0 0
Nucleus 0 0
Vacuole 6.3 7.6


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mdl1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available