Standard name
Human Ortholog
Description Protein involved in regulation of nonhomologous end joining; interacts with DNA ligase IV components Dnl4p and Lif1p; repressed by MAT heterozygosity; regulates cellular distribution of Lif1p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Bud Neck 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 – – – – – – – – – – 0 0 0 – – – – – – – – –
Cell Periphery 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.15 0.12 – – – – – – – – – – 0.23 0.28 0.3 – – – 0.08 0 0 0.11 0.14 0.14
Endoplasmic Reticulum 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Endosome 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Golgi 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0.34 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0.06 0.07
Nucleus 0.53 0.68 – – – – – – – – – – 0.71 0.63 0.59 – – – 0.56 0.73 1.0 0.45 0.35 0.28
Nuclear Periphery 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0.05
Vac/Vac Membrane 0.22 0.3 – – – – – – – – – – 0.1 0.11 0.14 – – – 0.25 0.15 0 0.31 0.31 0.34
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 – – – – – – – – – – 0 0 0 – – – 0 2 0 0 0 3
Bud 0 0 – – – – – – – – – – 0 0 0 – – – 3 7 0 3 4 6
Bud Neck 0 0 – – – – – – – – – – 0 2 0 – – – 0 0 0 1 1 4
Bud Site 0 0 – – – – – – – – – – 0 0 0 – – – – – – – – –
Cell Periphery 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 27 26 – – – – – – – – – – 24 85 114 – – – 16 4 0 15 27 38
Endoplasmic Reticulum 0 2 – – – – – – – – – – 0 2 1 – – – 0 1 0 1 0 1
Endosome 1 1 – – – – – – – – – – 0 1 9 – – – 1 2 0 2 2 6
Golgi 0 1 – – – – – – – – – – 0 1 1 – – – 0 1 0 0 0 2
Mitochondria 62 6 – – – – – – – – – – 1 2 1 – – – 4 2 0 2 10 20
Nucleus 98 143 – – – – – – – – – – 75 193 221 – – – 122 173 0 61 68 76
Nuclear Periphery 0 0 – – – – – – – – – – 0 0 1 – – – 1 1 0 0 0 0
Nucleolus 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 1 1
Peroxisomes 0 0 – – – – – – – – – – 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 – – – – – – – – – – 0 1 2 – – – 7 2 0 3 8 12
Vac/Vac Membrane 41 63 – – – – – – – – – – 11 33 53 – – – 54 35 0 42 60 92
Unique Cell Count 184 210 106 305 375 218 237 1 138 193 274
Labelled Cell Count 229 242 111 320 403 218 237 1 138 193 274


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.8 5.3 – – – – – – – – – – 5.4 5.8 5.5 – – – 5.1 5.7 6.2
Std Deviation (1e-4) 0.5 1.1 – – – – – – – – – – 1.1 1.6 1.3 – – – 1.2 2.2 2.0
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.1334 0.5604 0.4716 0.4753 0.1696 0.5227 0.8236 0.379 0.2639 -0.0819 1.5645 0.4601 -0.0073 0.4509 0.0906 0.4543 -0.018 0.3988
Actin 0.0006 0.0029 0.0001 0.0001 0.0002 0.0003 0.0177 0.0001 0.0014 0.0001 0.0302 0.0094 0.0057 0.0001 0.0028 0 0.0002 0.0002
Bud 0.0009 0.0003 0.0008 0 0.0001 0.0025 0.0005 0.0001 0.0001 0 0.0003 0.0003 0.0002 0.0003 0 0 0.0025 0
Bud Neck 0.0003 0.0007 0.0002 0.0001 0.0004 0.0017 0.0056 0.0006 0.0004 0.0003 0.0039 0.0036 0.0043 0.001 0.0003 0.0002 0.0007 0.0015
Bud Periphery 0.0004 0.0001 0.0002 0 0 0.0005 0.0007 0.0001 0.0001 0 0.0008 0.0004 0.0005 0.0001 0 0 0.0008 0
Bud Site 0.0002 0.0012 0.0002 0 0.0001 0.0005 0.0031 0.001 0.0004 0 0.0007 0.0008 0.0006 0.0101 0.0001 0.0001 0.0003 0.0001
Cell Periphery 0 0 0 0 0 0.0001 0.0003 0 0 0 0.0002 0.0001 0.0001 0 0 0 0.0002 0
Cytoplasm 0.0224 0.0482 0.0185 0.0101 0.0167 0.0341 0.0385 0.0544 0.0509 0.0176 0.0093 0.0326 0.0288 0.0595 0.0216 0.0255 0.0332 0.0133
Cytoplasmic Foci 0.0071 0.0016 0.0006 0.0002 0.0018 0.0046 0.0095 0.0009 0.0036 0.0007 0.0056 0.003 0.002 0.0046 0.0005 0.0002 0.0183 0.0004
Eisosomes 0 0 0 0 0 0 0.0002 0 0 0 0.0005 0.0001 0.0001 0 0 0 0 0
Endoplasmic Reticulum 0.0011 0.0011 0.0007 0.0001 0.0007 0.0004 0.0069 0.0014 0.001 0.0017 0.0086 0.0014 0.0015 0.0013 0.0007 0.0003 0.0005 0.0004
Endosome 0.0025 0.0017 0.0009 0.0002 0.0015 0.001 0.0214 0.001 0.0021 0.0007 0.0451 0.0079 0.0032 0.0015 0.0018 0.0003 0.0007 0.0013
Golgi 0.0001 0.0001 0 0 0 0 0.0046 0 0.0017 0 0.0158 0.0023 0.0005 0 0.0002 0 0 0
Lipid Particles 0.0009 0.0002 0.0001 0 0.0001 0.0001 0.0059 0.0001 0.001 0.0001 0.0763 0.0023 0.0007 0.0001 0.0002 0 0.0005 0.0002
Mitochondria 0.0006 0.0003 0.0003 0.0002 0.0003 0.0006 0.0033 0.0005 0.0021 0.0005 0.0154 0.001 0.0045 0.0009 0.0003 0.0002 0.0061 0.0002
None 0.0383 0.039 0.052 0.0799 0.083 0.05 0.0406 0.0998 0.0906 0.0637 0.0055 0.0273 0.026 0.0225 0.0323 0.0366 0.0678 0.0034
Nuclear Periphery 0.0177 0.0133 0.0193 0.0071 0.0111 0.0095 0.0526 0.0134 0.0093 0.0264 0.1342 0.0146 0.0104 0.0153 0.0065 0.0046 0.0098 0.0084
Nucleolus 0.0062 0.0062 0.0055 0.0054 0.007 0.011 0.0076 0.0056 0.0039 0.005 0.0087 0.0096 0.0054 0.0038 0.0028 0.0035 0.0086 0.007
Nucleus 0.8532 0.8355 0.867 0.8606 0.8368 0.809 0.7177 0.8019 0.7931 0.8639 0.5715 0.8252 0.8558 0.8563 0.9224 0.8611 0.7792 0.9356
Peroxisomes 0.0002 0.0007 0 0 0 0.0001 0.0163 0 0.0064 0 0.0133 0.0007 0.0006 0.0001 0.0001 0 0.0005 0.0001
Punctate Nuclear 0.0458 0.0446 0.0331 0.0356 0.0393 0.0731 0.041 0.0177 0.0311 0.0182 0.0445 0.0563 0.0468 0.0208 0.0067 0.0671 0.0685 0.0271
Vacuole 0.0008 0.0019 0.0004 0.0001 0.0006 0.0007 0.0039 0.0011 0.0006 0.0005 0.0026 0.0008 0.0016 0.0013 0.0004 0.0002 0.001 0.0007
Vacuole Periphery 0.0006 0.0003 0.0002 0.0001 0.0002 0.0002 0.002 0.0003 0.0002 0.0004 0.0069 0.0005 0.0005 0.0003 0.0001 0.0001 0.0005 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.8977 9.5858 6.4018 11.1751 4.866 9.6454 7.996 10.4665 7.8537 11.8579
Translational Efficiency 1.0678 0.4587 0.9036 0.4568 1.1211 0.7223 0.5832 0.5339 0.7489 0.4468

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1343 334 148 143 1654 2116 2110 820 2997 2450 2258 963

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 634.71 770.34 862.82 895.25 654.64 711.69 810.59 810.73 645.71 719.69 814.01 823.28
Standard Deviation 65.50 89.87 118.75 106.50 75.82 84.65 98.92 106.36 72.06 87.72 101.17 110.55
Intensity Change Log 2 — 0.279398 0.442962 0.496193 — 0.120547 0.308271 0.308520 — 0.200931 0.376147 0.403957

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000086 0.002091 0.000478 0.001081 0.000071 0.000131 0.000269 0.001374 0.000078 0.000398 0.000282 0.001330
Bud Neck 0.007263 0.011879 0.003519 0.004804 0.003774 0.007257 0.005992 0.006850 0.005337 0.007887 0.005830 0.006546
Bud Site 0.002555 0.004435 0.001347 0.007419 0.002944 0.002752 0.002745 0.007156 0.002769 0.002982 0.002653 0.007195
Cell Periphery 0.000154 0.000195 0.000081 0.000161 0.000228 0.000114 0.000090 0.000100 0.000195 0.000125 0.000090 0.000109
Cytoplasm 0.249814* 0.116390* 0.006432 0.044281 0.245059* 0.138615* 0.047248 0.054813 0.247190* 0.135585* 0.044573 0.053249
Cytoplasmic Foci 0.085668 0.042895 0.000533 0.000498 0.029425 0.014643 0.000935 0.004521 0.054628 0.018494 0.000909 0.003923
Eisosomes 0.000072 0.000077 0.000037 0.000056 0.000029 0.000021 0.000013 0.000026 0.000048 0.000028 0.000014 0.000031
Endoplasmic Reticulum 0.000956 0.004586 0.006798 0.016843 0.000806 0.001196 0.002645 0.004833 0.000873 0.001658 0.002917 0.006616
Endosome 0.002215 0.002876 0.001251 0.000958 0.001022 0.002008 0.000710 0.005001 0.001556 0.002126 0.000746 0.004401
Golgi 0.001217 0.001857 0.000037 0.000062 0.000239 0.001126 0.000265 0.004574 0.000677 0.001226 0.000250 0.003904
Lipid Particles 0.006088 0.004846 0.000597 0.000797 0.002768 0.001490 0.000219 0.000843 0.004256 0.001948 0.000244 0.000836
Mitochondria 0.005853 0.004253 0.000737 0.001017 0.001303 0.005847 0.001216 0.005754 0.003342 0.005630 0.001185 0.005051
Mitotic Spindle 0.003533 0.006071 0.000055 0.000727 0.002079 0.005264 0.006703 0.016542 0.002731 0.005374 0.006268 0.014194
None 0.008367 0.005286 0.001457 0.004065 0.007244 0.006054 0.004303 0.003965 0.007747 0.005950 0.004116 0.003980
Nuclear Periphery 0.001022 0.001449 0.000748 0.001719 0.001205 0.001325 0.001398 0.001505 0.001123 0.001342 0.001356 0.001537
Nuclear Periphery Foci 0.000311 0.000639 0.000148 0.000657 0.000326 0.000526 0.000243 0.001385 0.000319 0.000542 0.000237 0.001277
Nucleolus 0.003423 0.006640 0.001710 0.000873 0.001808 0.002200 0.000823 0.000972 0.002532 0.002805 0.000881 0.000957
Nucleus 0.606817* 0.764190* 0.963153* 0.884400* 0.692813* 0.802656* 0.919443* 0.860826* 0.654277* 0.797412* 0.922308* 0.864327*
Peroxisomes 0.005780 0.007469 0.000178 0.000327 0.000844 0.001617 0.000108 0.000852 0.003056 0.002415 0.000112 0.000774
Vacuole 0.008372 0.011250 0.009799 0.029120 0.005555 0.004552 0.004139 0.016740 0.006817 0.005465 0.004510 0.018578
Vacuole Periphery 0.000433 0.000626 0.000903 0.000135 0.000458 0.000606 0.000495 0.001368 0.000447 0.000609 0.000522 0.001185

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.27 -5.71 -7.68 0.22 -4.49 -2.68 -4.23 -2.48 -2.35 -1.90 -1.49 -4.78 -3.06 -2.00 -2.34
Bud Neck -1.50 1.08 -1.59 0.87 -1.96 -3.27 -3.30 -4.71 -2.20 -2.47 -2.65 -1.83 -4.17 -1.84 -2.72
Bud Site -1.30 1.00 -1.78 -1.07 -2.03 0.16 0.00 -2.30 -2.57 -2.47 -0.33 -0.13 -2.95 -2.79 -2.89
Cell Periphery -1.18 3.84 -2.03 -0.18 -4.25 2.43 3.04 2.55 0.31 -2.16 2.54 4.07 2.69 0.11 -3.65
Cytoplasm 11.77 36.93 18.32 5.36 -4.16 14.52 31.03 24.62 13.04 -2.38 19.20 42.17 31.62 14.12 -2.77
Cytoplasmic Foci 6.88 22.16 22.14 8.62 -0.69 6.65 15.66 12.93 7.80 -3.20 14.87 26.15 23.67 10.87 -3.18
Eisosomes -0.49 3.74 -1.31 -0.47 -3.66 4.64 8.92 -4.89 -8.18 -10.81 8.21 16.86 -0.38 -6.85 -12.28
Endoplasmic Reticulum -7.58 -8.21 -10.71 -8.37 -5.90 -4.07 -16.11 -15.34 -14.60 -10.19 -7.52 -17.84 -18.00 -16.34 -12.40
Endosome -0.82 1.66 2.44 2.35 -0.43 -2.13 1.78 -2.89 -1.48 -3.33 -1.24 3.99 -2.12 -1.22 -3.43
Golgi -0.54 2.41 2.29 1.72 -3.79 -2.16 0.25 -1.93 -1.08 -1.97 -1.24 1.94 -1.41 -0.82 -1.96
Lipid Particles 1.29 9.97 9.13 4.62 -2.27 3.59 7.97 5.35 2.94 -5.52 6.69 13.50 10.41 4.95 -6.29
Mitochondria 1.10 4.40 3.82 3.20 -2.45 -4.24 0.07 -1.60 1.16 -1.63 -2.17 3.71 -0.03 1.43 -1.67
Mitotic Spindle -1.25 2.50 -0.80 0.02 -1.48 -2.38 -3.12 -4.32 -3.37 -2.80 -2.32 -2.64 -4.24 -3.24 -2.86
None 2.34 6.59 3.30 1.05 -3.15 1.28 3.60 3.55 2.62 -0.15 2.25 5.16 4.97 2.81 -0.46
Nuclear Periphery -2.69 0.30 -6.41 -4.76 -6.29 -0.73 -2.94 -8.24 -7.47 -5.68 -1.71 -3.80 -10.47 -8.46 -6.63
Nuclear Periphery Foci -2.16 1.32 -4.59 -2.66 -5.25 -0.97 0.66 -2.65 -1.97 -2.88 -1.23 0.93 -3.05 -2.19 -3.29
Nucleolus -2.20 3.45 4.94 4.21 1.33 -0.51 2.53 2.17 3.65 -1.01 -0.27 5.02 5.06 5.37 -0.88
Nucleus -9.09 -27.98 -11.04 -2.66 6.26 -12.28 -28.57 -11.30 -1.93 9.63 -19.16 -42.04 -17.25 -2.71 10.86
Peroxisomes -0.58 6.39 6.23 2.93 -1.16 -2.51 5.95 1.28 3.01 -1.66 1.21 7.33 5.72 4.21 -1.75
Vacuole -2.84 -1.88 -5.30 -4.94 -3.94 1.24 -0.84 -9.73 -9.96 -9.60 2.04 -0.27 -10.86 -11.12 -10.74
Vacuole Periphery -1.38 -0.47 4.63 3.64 0.91 -0.57 0.20 -0.84 -0.51 -1.03 -0.94 0.12 -0.81 -0.27 -0.82
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein involved in regulation of nonhomologous end joining; interacts with DNA ligase IV components Dnl4p and Lif1p; repressed by MAT heterozygosity; regulates cellular distribution of Lif1p
Localization
Cell Percentages nucleus (43%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Nej1

Nej1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Nej1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available