Standard name
Human Ortholog
Description Gamma-glutamyltranspeptidase; major glutathione-degrading enzyme; involved in detoxification of electrophilic xenobiotics; expression induced mainly by nitrogen starvation
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.5 0.52 – 0.66 0.4 0.36 0.29 0.39 0.37 0.49 0.52 0.57 0.86 0.89 0.98 0.64 0.61 0.57 0.05 0.06 0.05 0.1 0.14 0.11
Endoplasmic Reticulum 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Endosome 0.06 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0
Golgi 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.11 0 – 0 0 0 0 0 0 0.05 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.09 0.05 – 0 0.14 0.26 0.22 0.25 0.28 0.17 0.16 0.09 0.11 0 0 0.05 0.06 0.05 0 0 0 0 0 0
Nuclear Periphery 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.4 0.57 – 0.34 0.67 0.67 0.66 0.63 0.6 0.57 0.54 0.58 0.14 0.14 0 0.5 0.49 0.49 0.86 0.84 0.87 0.83 0.77 0.78
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 – 1 0 0 0 0 0 0 1 1 0 1 0 0 0 0 1 1 0 0 3 3
Bud Neck 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 1
Bud Site 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 – 1 1 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0
Cytoplasm 110 85 – 61 76 62 95 135 49 102 92 171 89 221 346 213 224 156 14 10 2 9 34 31
Endoplasmic Reticulum 0 0 – 1 4 1 7 2 3 2 3 0 2 0 1 7 6 14 7 0 0 0 0 0
Endosome 13 7 – 0 3 2 0 3 0 0 0 0 1 0 0 8 6 5 11 9 0 1 5 6
Golgi 0 1 – 0 0 0 1 0 0 0 0 0 0 0 0 2 5 0 1 0 0 0 0 3
Mitochondria 25 1 – 0 1 2 11 6 5 10 13 9 0 0 1 8 9 4 2 3 0 0 4 5
Nucleus 20 9 – 4 26 45 71 88 37 36 29 28 11 4 1 16 22 14 1 1 0 1 2 3
Nuclear Periphery 4 1 – 1 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 8 0 – 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1
Peroxisomes 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 1 0 – 0 1 1 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 2 2
Vac/Vac Membrane 87 93 – 31 128 114 215 217 79 117 96 174 15 34 15 166 181 133 272 149 36 71 191 217
Unique Cell Count 220 164 92 190 170 326 347 132 207 178 300 104 247 354 335 367 273 318 179 42 87 249 280
Labelled Cell Count 268 197 100 240 227 401 451 173 267 234 386 118 260 364 422 454 329 318 179 42 87 249 280


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.4 5.3 – 6.1 7.9 7.2 7.1 7.3 5.8 6.1 5.6 6.0 5.6 5.6 5.2 6.5 6.4 7.6 4.7 5.6 5.9
Std Deviation (1e-4) 0.7 0.9 – 1.6 1.6 1.5 1.5 1.7 1.4 1.5 1.4 1.4 1.1 1.6 1.1 1.4 1.6 4.8 0.7 1.3 2.1
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –

RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510HU80HU120HU1600510rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.562 -0.6683 -0.7141 -1.0266 -1.4666 -0.5924 -0.4617 -0.043 -0.1041 -0.2942 -0.3962 -0.2256 -1.1529 -1.0593 -1.2666 -0.763 -0.8083 -0.9172
Actin 0.0483 0.0055 0.0223 0.001 0.0064 0.0232 0.031 0.0001 0.0022 0.0074 0.0002 0.0035 0.0271 0.0003 0.0148 0.0028 0.0844 0.0014
Bud 0.001 0.0004 0.0006 0.0002 0.0004 0.0005 0.0013 0.0009 0.0036 0.0023 0.002 0.0006 0.0007 0.0005 0.0011 0.0007 0.0018 0.0005
Bud Neck 0.0038 0.0003 0.0011 0.0004 0.0019 0.003 0.0073 0.0018 0.0036 0.0036 0.0016 0.0033 0.0018 0.0006 0.0043 0.0067 0.0056 0.0039
Bud Periphery 0.0021 0.001 0.0008 0.0004 0.0003 0.0007 0.0019 0.0017 0.0038 0.0065 0.0026 0.001 0.0016 0.0006 0.0022 0.0008 0.0036 0.0009
Bud Site 0.0043 0.0013 0.0046 0.0002 0.002 0.0008 0.0075 0.0046 0.0134 0.0235 0.0048 0.0009 0.0055 0.0024 0.0073 0.0166 0.0054 0.0008
Cell Periphery 0.0007 0.0005 0.0004 0.0002 0.0001 0.0003 0.0016 0.0008 0.0006 0.0018 0.0007 0.0008 0.0007 0.0005 0.0007 0.0004 0.0008 0.0005
Cytoplasm 0.1005 0.27 0.1881 0.2182 0.2432 0.3033 0.1279 0.2275 0.1714 0.162 0.1007 0.2338 0.154 0.1863 0.1641 0.2862 0.0707 0.2863
Cytoplasmic Foci 0.0674 0.0486 0.0721 0.1037 0.0288 0.0707 0.0614 0.0444 0.0561 0.0829 0.0879 0.0635 0.0729 0.0546 0.0608 0.0634 0.0952 0.0567
Eisosomes 0.0013 0.0003 0.0002 0.0003 0.0039 0.0001 0.0006 0.0001 0.0002 0.0003 0.0001 0.0001 0.0006 0.0001 0.0003 0.0002 0.0002 0
Endoplasmic Reticulum 0.0075 0.0048 0.0067 0.0043 0.005 0.0039 0.0076 0.0064 0.0038 0.0038 0.002 0.0053 0.005 0.0028 0.0034 0.0045 0.0036 0.0041
Endosome 0.1323 0.0786 0.1562 0.2428 0.2037 0.1624 0.0831 0.0811 0.0935 0.1247 0.2081 0.1473 0.1127 0.0913 0.1467 0.2095 0.192 0.1283
Golgi 0.0143 0.0011 0.0045 0.0016 0.0018 0.0094 0.012 0.0011 0.0052 0.0099 0.0079 0.0053 0.0153 0.0012 0.0054 0.0023 0.0186 0.0058
Lipid Particles 0.0332 0.0056 0.0123 0.0031 0.0035 0.0105 0.0472 0.0046 0.0111 0.0169 0.0324 0.0063 0.0344 0.0064 0.0103 0.0033 0.0268 0.0055
Mitochondria 0.0069 0.0017 0.0035 0.0017 0.0016 0.0115 0.0163 0.0033 0.0115 0.0436 0.0177 0.0028 0.0119 0.0015 0.0054 0.0024 0.0151 0.0044
None 0.4838 0.449 0.389 0.2972 0.2303 0.2058 0.4806 0.4871 0.5296 0.3134 0.3139 0.291 0.4169 0.4954 0.442 0.2275 0.3092 0.2733
Nuclear Periphery 0.0151 0.0025 0.0051 0.0042 0.0088 0.0032 0.0105 0.0037 0.002 0.0044 0.0018 0.0038 0.0054 0.0025 0.0033 0.0105 0.0032 0.0046
Nucleolus 0.0014 0.0011 0.0013 0.0009 0.0011 0.0013 0.003 0.0023 0.0024 0.0116 0.0048 0.0019 0.0025 0.0022 0.002 0.0011 0.0029 0.0033
Nucleus 0.0026 0.0033 0.0053 0.0029 0.0263 0.0209 0.0049 0.0088 0.0053 0.0164 0.0042 0.0131 0.006 0.0066 0.0039 0.0109 0.0054 0.0126
Peroxisomes 0.0231 0.0005 0.0152 0.0008 0.0023 0.0081 0.0183 0.0005 0.0063 0.0118 0.0049 0.0016 0.0179 0.0006 0.0033 0.001 0.0357 0.0013
Punctate Nuclear 0.0075 0.0019 0.0034 0.0013 0.0036 0.0174 0.0109 0.0012 0.0024 0.0061 0.0092 0.0027 0.0116 0.0016 0.0028 0.0018 0.005 0.0019
Vacuole 0.0364 0.1167 0.0976 0.1049 0.2012 0.1319 0.0605 0.1119 0.067 0.1308 0.1744 0.199 0.0883 0.1342 0.105 0.1245 0.1046 0.1903
Vacuole Periphery 0.0065 0.0054 0.0096 0.01 0.0239 0.011 0.0046 0.0058 0.0049 0.0163 0.018 0.0124 0.0072 0.0079 0.0108 0.0232 0.0103 0.0134

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.6326 3.9793 15.5024 16.5219 12.2645 24.4694 14.4594 19.0091 20.1996 16.6846
Translational Efficiency 1.4937 3.5357 0.9496 1.3131 1.1325 1.1435 1.1761 1.0562 1.2008 1.0204

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1698 880 1347 1623 159 1242 1764 398 1857 2122 3111 2021

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 627.66 716.31 813.38 815.93 759.21 703.14 855.70 845.50 638.92 708.60 837.38 821.75
Standard Deviation 71.65 109.06 88.97 119.80 78.86 94.62 91.39 107.74 81.12 101.07 92.75 118.11
Intensity Change Log 2 — 0.190601 0.373946 0.378462 — -0.110687 0.172606 0.155306 — 0.033499 0.267221 0.260593

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000067 0.000319 0.000203 0.000556 0.000116 0.000176 0.000076 0.000723 0.000071 0.000235 0.000131 0.000589
Bud Neck 0.035464 0.022586 0.007184 0.011286 0.015486 0.034374 0.006521 0.006135 0.033753 0.029485 0.006808 0.010271
Bud Site 0.008433 0.021958 0.012156 0.036756 0.004380 0.020679 0.002760 0.036208 0.008086 0.021209 0.006828 0.036648
Cell Periphery 0.000159 0.000151 0.000131 0.000120 0.000193 0.000108 0.000089 0.000134 0.000162 0.000126 0.000108 0.000123
Cytoplasm 0.218752 0.274590 0.451872 0.461217 0.218560 0.168328 0.530861 0.446111 0.218735 0.212395 0.496660 0.458242
Cytoplasmic Foci 0.120265 0.122817 0.030590 0.040959 0.126550 0.134007 0.044236 0.050506 0.120803 0.129366 0.038328 0.042839
Eisosomes 0.000097 0.000081 0.000042 0.000050 0.000110 0.000082 0.000043 0.000061 0.000098 0.000082 0.000042 0.000052
Endoplasmic Reticulum 0.001557 0.001102 0.002747 0.001166 0.001516 0.001309 0.001714 0.002336 0.001553 0.001223 0.002161 0.001397
Endosome 0.134083 0.077428 0.007758 0.015058 0.072497 0.149714 0.014586 0.011411 0.128810 0.119737 0.011630 0.014339
Golgi 0.001583 0.002945 0.000143 0.005021 0.000923 0.006626 0.000149 0.001217 0.001527 0.005100 0.000146 0.004271
Lipid Particles 0.009142 0.005301 0.001821 0.001554 0.004982 0.005771 0.002480 0.001905 0.008786 0.005576 0.002195 0.001623
Mitochondria 0.003015 0.006961 0.000697 0.004720 0.000254 0.007707 0.000244 0.002478 0.002778 0.007398 0.000440 0.004278
Mitotic Spindle 0.000201 0.006622 0.007160 0.060977 0.002453 0.008512 0.004187 0.032815 0.000394 0.007728 0.005474 0.055431
None 0.001575 0.001688 0.003700 0.004620 0.000226 0.001085 0.003691 0.006852 0.001459 0.001335 0.003695 0.005059
Nuclear Periphery 0.000299 0.000623 0.002159 0.001186 0.000412 0.000387 0.001632 0.001038 0.000309 0.000485 0.001860 0.001157
Nuclear Periphery Foci 0.000400 0.000689 0.001633 0.001194 0.000584 0.000258 0.003078 0.001411 0.000415 0.000437 0.002452 0.001237
Nucleolus 0.001490 0.002520 0.000689 0.000664 0.000630 0.001232 0.001516 0.000311 0.001416 0.001767 0.001158 0.000595
Nucleus 0.034654 0.048901 0.393564 0.121322 0.042963 0.024754 0.226854 0.158979 0.035365 0.034768 0.299036 0.128738
Peroxisomes 0.004311 0.006935 0.001005 0.001900 0.003979 0.007568 0.000852 0.003758 0.004282 0.007305 0.000918 0.002266
Vacuole 0.419442 0.391376 0.074481 0.224897 0.500922 0.415574 0.154182 0.235082 0.426419 0.405539 0.119673 0.226902
Vacuole Periphery 0.005012 0.004408 0.000267 0.004779 0.002264 0.011747 0.000249 0.000529 0.004777 0.008704 0.000257 0.003942

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.45 -6.20 -3.13 -0.38 -1.16 -0.91 0.47 -3.22 -2.82 -4.57 -4.60 -4.33 -3.84 -1.58 -2.71
Bud Neck 4.59 12.16 11.04 5.35 -2.28 -5.67 3.01 4.14 13.01 2.84 1.77 13.20 11.94 11.71 -2.13
Bud Site -4.43 -1.28 -6.09 -0.16 -3.95 -7.67 1.34 -3.59 0.18 -3.93 -7.28 1.46 -6.75 -0.22 -7.29
Cell Periphery 0.24 1.27 4.71 2.62 6.14 4.08 5.25 4.46 0.85 -1.61 2.13 3.88 5.21 3.12 3.47
Cytoplasm -5.68 -20.37 -20.51 -11.52 0.56 2.65 -14.03 -6.59 -13.09 7.64 0.67 -31.68 -21.52 -22.46 6.63
Cytoplasmic Foci -0.38 22.99 21.97 18.02 -2.08 -0.60 7.63 8.63 18.44 3.65 -1.72 22.88 23.70 26.59 2.25
Eisosomes 2.44 9.46 9.86 5.88 -0.29 2.58 6.36 4.12 2.49 -5.40 3.02 11.55 10.09 7.31 -3.05
Endoplasmic Reticulum 2.25 -8.89 0.98 -1.61 10.47 0.39 -1.31 -2.54 -4.45 -2.74 1.59 -7.37 -0.59 -2.39 8.35
Endosome 9.57 26.89 26.43 15.71 -1.63 -8.43 7.52 8.63 27.57 4.96 1.81 27.04 27.52 30.70 2.19
Golgi -1.69 9.04 -1.00 0.54 -3.16 -5.71 2.02 1.11 6.50 -0.96 -5.56 9.23 -0.67 3.80 -3.23
Lipid Particles 3.62 9.29 10.00 4.90 2.95 -0.37 1.29 1.67 7.12 3.22 3.82 9.04 10.09 8.71 4.73
Mitochondria -1.80 3.65 0.62 2.06 -2.30 -8.28 -0.21 -1.75 6.94 -1.74 -4.04 4.04 0.79 4.57 -2.78
Mitotic Spindle -3.10 -5.11 -11.00 -8.23 -8.59 -1.93 -1.11 -2.79 -1.62 -2.40 -5.10 -6.23 -11.49 -8.37 -9.25
None -0.10 -3.35 -2.05 -2.08 0.06 -2.68 -7.23 -5.36 -4.17 -1.82 0.35 -3.65 -2.99 -3.66 -0.58
Nuclear Periphery -2.25 -19.35 -16.48 -8.03 4.23 0.08 -14.36 -9.23 -9.59 0.27 -2.35 -27.02 -18.92 -13.65 2.94
Nuclear Periphery Foci -2.45 -7.53 -5.17 -3.13 3.35 3.75 -6.79 -6.12 -8.54 4.29 -0.41 -9.16 -6.49 -6.89 5.66
Nucleolus -1.58 4.94 3.65 2.36 -1.54 -3.07 -3.33 2.01 4.52 3.97 -1.21 -0.02 4.34 3.07 2.58
Nucleus -4.32 -44.95 -23.04 -17.53 29.25 2.95 -24.05 -13.05 -16.27 2.62 0.07 -52.67 -26.76 -26.73 24.59
Peroxisomes -1.99 8.59 7.04 4.54 -1.09 -2.21 2.14 1.59 6.21 -0.85 -4.02 9.72 7.14 8.49 -1.56
Vacuole 2.36 38.88 10.44 6.50 -26.24 3.23 12.31 5.64 4.52 -9.30 2.19 35.36 11.40 9.60 -22.77
Vacuole Periphery 1.81 18.49 4.03 2.83 -3.12 -11.26 6.49 6.38 14.65 -0.19 -7.19 19.17 5.19 9.65 -3.15
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Gamma-glutamyltranspeptidase; major glutathione-degrading enzyme; involved in detoxification of electrophilic xenobiotics; expression induced mainly by nitrogen starvation
Localization
Cell Percentages vacuole (79%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Ecm38

Ecm38


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ecm38-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available