Standard name
Human Ortholog
Description Member of the ChAPs family (Chs5p-Arf1p-binding proteins); members include Bch1p, Bch2p, Bud7p, and Chs6p; ChAPs family proteins form the exomer complex with Chs5p to mediate export of specific cargo proteins from the Golgi to the plasma membrane; interacts selectively with the activated, GTP-bound form of Arf1p; may interact with ribosomes; protein abundance increases and forms cytoplasmic foci in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.22 0.22 0.33 0.22 0.24 0.07 0.15 0.14 0.1 0.1 0.13 0.18 0.07 0 0 – – – 0.08 0.07 0 0.1 0.09 0.12
Bud 0 0 0 0 0.06 0.06 0.07 0.05 0.06 0.06 0.07 0.07 0.05 0 0 – – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0 0.07 0 0.06 0.05 0 0 0 0 0 0.05 0 0.05 0.05 0.06 – – – 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.16 0.06 0 0 0 0 0 0 0 0.06 0.06 0.08 0 0 – – – 0 0 0 0 0 0
Endosome 0.12 0.09 0.12 0.12 0.15 0.22 0.17 0.18 0.11 0.13 0.11 0.22 0.05 0.14 0.14 – – – 0.19 0.21 0.26 0.14 0.1 0.09
Golgi 0.6 0.5 0.61 0.66 0.43 0.25 0.24 0.28 0.14 0.11 0.11 0.19 0.59 0.66 0.66 – – – 0.61 0.55 0.57 0.62 0.66 0.67
Mitochondria 0.53 0.39 0.15 0.3 0.35 0.55 0.62 0.36 0.75 0.7 0.62 0.4 0.41 0.18 0.29 – – – 0 0.06 0.05 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0.06 0.1 0.06 0.05 0.07 0.08 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0.07 0.08
SpindlePole 0 0 0.06 0.05 0.1 0.06 0.07 0.09 0 0.06 0.05 0.1 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0 0.07 0.07 0 0 0.07 0 0.09 0 0 0.06 0.08 0 0.06 0 – – – 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 73 73 156 79 92 39 90 70 56 60 76 117 19 11 13 – – – 31 26 23 22 26 34
Bud 11 7 16 11 22 34 42 24 34 39 42 49 14 9 6 – – – 0 2 0 1 1 0
Bud Neck 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 2 3 2 5 7 5 2 0 0 0 – – – – – – – – –
Cell Periphery 3 6 1 5 2 5 2 2 5 1 4 8 2 3 1 – – – 0 0 0 0 0 0
Cytoplasm 8 23 20 22 19 13 10 14 15 22 29 17 14 16 18 – – – 0 5 2 2 0 1
Endoplasmic Reticulum 14 52 29 13 14 14 21 7 17 11 36 40 21 12 11 – – – 2 5 2 1 3 1
Endosome 40 30 56 44 58 121 97 90 59 77 66 145 15 49 43 – – – 77 81 159 33 29 26
Golgi 200 164 293 238 163 136 138 138 73 68 65 127 161 228 207 – – – 244 212 345 141 197 200
Mitochondria 177 127 74 106 132 300 358 174 403 428 366 267 111 63 91 – – – 11 22 29 9 12 6
Nucleus 0 0 0 1 1 1 1 2 2 2 2 0 0 1 0 – – – 1 0 0 0 0 0
Nuclear Periphery 0 0 1 1 0 2 6 3 8 4 5 6 1 1 1 – – – 1 0 1 0 0 0
Nucleolus 3 2 4 1 8 14 34 50 31 32 40 51 0 11 9 – – – 0 0 0 0 0 0
Peroxisomes 1 0 2 1 5 29 13 7 10 9 6 17 3 4 5 – – – 15 8 23 9 21 24
SpindlePole 4 2 29 19 40 34 43 43 18 34 28 64 1 9 3 – – – 3 4 5 3 1 0
Vac/Vac Membrane 13 23 36 14 14 38 21 42 18 27 38 52 12 21 14 – – – 6 14 7 2 0 0
Unique Cell Count 333 329 480 358 382 544 581 488 539 612 594 664 273 348 312 401 387 605 230 299 297
Labelled Cell Count 547 509 717 555 571 782 879 668 754 821 809 962 374 438 422 401 387 605 230 299 297


Late Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 11.0 10.2 10.1 9.6 9.3 8.8 8.5 8.9 8.0 7.9 7.7 8.5 11.6 12.0 12.1 – – – 9.7 10.2 10.5
Std Deviation (1e-4) 1.7 1.7 1.2 1.2 1.5 1.3 1.2 1.4 1.4 1.5 1.4 1.5 1.7 1.7 1.9 – – – 1.6 1.4 1.6
Intensity Change (Log2) – – – -0.06 -0.12 -0.2 -0.24 -0.18 -0.33 -0.36 -0.38 -0.24 0.21 0.26 0.26 – – – -0.05 0.02 0.06

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -3.3 -2.7 -10.3 -6.5 -6.7 -8.7 -9.3 -7.8 -5.8 -8.0 -10.4 -9.5 – – –
Bud -0.2 1.7 2.2 2.8 1.2 2.2 2.3 2.7 2.9 1.2 -0.6 -1.2 – – –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Cytoplasm 1.3 0.6 -1.6 -2.4 -1.1 -1.2 -0.5 0.6 -1.5 0.6 0.3 1.0 – – –
Endoplasmic Reticulum -1.6 -1.6 -2.8 -1.9 -3.8 -2.2 -3.7 0 0 0.9 -1.7 -1.6 – – –
Endosome 0.3 1.5 4.5 2.3 2.9 -0.4 0.5 -0.3 4.5 -2.8 1.0 0.9 – – –
Golgi 1.6 -5.4 -11.7 -12.3 -10.3 -15.8 -17.4 -17.3 -14.5 -0.6 1.3 1.5 – – –
Mitochondria 4.9 6.5 13.2 15.2 7.2 19.0 17.9 15.3 9.0 7.7 1.0 4.7 – – –
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Nucleolus 0 1.6 2.1 4.4 6.4 4.3 4.0 4.9 5.3 0 2.5 2.2 – – –
Peroxisomes 0 0 4.6 2.5 0 2.1 0 0 2.8 0 0 0 – – –
SpindlePole -0.5 2.4 0.1 0.9 1.6 -2.1 -0.3 -1.0 2.2 -3.8 -2.3 -3.5 – – –
Vacuole -2.2 -2.4 -0.3 -2.8 0.6 -3.0 -2.2 -0.7 0.2 -1.7 -0.8 -1.7 – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.7304 7.7774 7.0218 6.6468 5.7725 6.4576 8.3015 9.9889 9.0251 9.0616 8.5232 9.4413 7.2186 9.2846 8.6351 7.7728 8.2601 8.5175
Actin 0.047 0.0115 0.009 0.0026 0.0301 0.0202 0.0426 0.0105 0.0137 0.0015 0.0015 0.0071 0.0488 0.0321 0.0286 0.0047 0.0145 0.0156
Bud 0.0004 0.0008 0.0004 0.0001 0.0008 0.0005 0.0003 0.0003 0.0002 0.0001 0.0001 0.0001 0.0006 0.0005 0.0018 0.0001 0.0017 0.0001
Bud Neck 0.0013 0.0005 0.0005 0.0003 0.0014 0.0009 0.0008 0.0003 0.0004 0.0002 0.0001 0.0002 0.002 0.0006 0.0006 0.0003 0.0012 0.0004
Bud Periphery 0.0005 0.0005 0.0002 0.0001 0.0007 0.0005 0.0004 0.0001 0.0001 0.0001 0 0 0.0005 0.0002 0.0019 0.0001 0.0038 0.0001
Bud Site 0.0019 0.0071 0.0014 0.0003 0.0018 0.0005 0.0021 0.0006 0.0003 0.0001 0.0001 0.0001 0.0047 0.0027 0.0017 0.0002 0.0027 0.0002
Cell Periphery 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0.0002 0 0 0 0 0 0.0002 0.0001 0.0001 0 0.0007 0
Cytoplasm 0.0137 0.012 0.0045 0.0025 0.0047 0.0044 0.0037 0.0093 0.0041 0.0024 0.0092 0.002 0.0068 0.0217 0.0243 0.0029 0.0036 0.0021
Cytoplasmic Foci 0.1207 0.1963 0.1583 0.1303 0.1214 0.0973 0.1299 0.1901 0.1455 0.0852 0.12 0.0994 0.1362 0.1969 0.1442 0.1006 0.1086 0.0864
Eisosomes 0.0007 0 0 0 0.0001 0.0001 0.0004 0 0 0 0 0 0.0002 0 0 0 0.0001 0
Endoplasmic Reticulum 0.0039 0.0003 0.0009 0.0004 0.0012 0.0023 0.0016 0.0003 0.0003 0.0004 0.0003 0.0003 0.0051 0.0012 0.0027 0.0004 0.0017 0.0009
Endosome 0.2349 0.2323 0.2556 0.3432 0.2584 0.1878 0.2211 0.2476 0.1977 0.2554 0.2395 0.1382 0.2372 0.2694 0.2557 0.3243 0.327 0.1762
Golgi 0.4794 0.5024 0.5092 0.494 0.5115 0.6201 0.5435 0.5215 0.5975 0.6463 0.6196 0.7401 0.4224 0.4262 0.5125 0.553 0.4463 0.6884
Lipid Particles 0.0258 0.0056 0.0154 0.0069 0.004 0.0248 0.0146 0.0021 0.0067 0.0018 0.0018 0.0016 0.0154 0.007 0.0025 0.0026 0.0169 0.0047
Mitochondria 0.0188 0.0056 0.0132 0.0023 0.0515 0.0223 0.0107 0.0027 0.0047 0.0028 0.0008 0.0037 0.0271 0.0021 0.0043 0.0018 0.025 0.0041
None 0.0087 0.0001 0.0001 0.0001 0.0001 0.0003 0.0012 0 0.0001 0 0 0.0001 0.002 0.0001 0.0003 0 0.0003 0.0002
Nuclear Periphery 0.0078 0.0001 0.0031 0.0002 0.0003 0.0018 0.0035 0.0001 0.0002 0.0001 0.0001 0.0007 0.0087 0.0004 0.0011 0.0001 0.0019 0.0092
Nucleolus 0.0036 0 0.0002 0.0002 0.0001 0.0001 0.0004 0 0 0 0 0 0.0011 0.0003 0 0 0.0004 0.0001
Nucleus 0.0026 0.0001 0.0005 0.0001 0.0001 0.0003 0.0009 0 0.0001 0 0 0.0001 0.0031 0.0002 0.0024 0 0.0015 0.0007
Peroxisomes 0.0144 0.0224 0.0209 0.0041 0.0065 0.0116 0.0135 0.0122 0.0259 0.001 0.0049 0.0046 0.0592 0.0275 0.0086 0.0045 0.0059 0.0053
Punctate Nuclear 0.0097 0.0002 0.0025 0.0001 0.0003 0.0008 0.0057 0.0002 0.001 0.0001 0.0001 0.0007 0.0059 0.0004 0.0003 0.0001 0.0004 0.0032
Vacuole 0.0017 0.0012 0.002 0.0099 0.0026 0.0016 0.0013 0.0009 0.0006 0.0012 0.0008 0.0004 0.0087 0.0085 0.004 0.0019 0.0256 0.0008
Vacuole Periphery 0.0022 0.0009 0.002 0.0023 0.0023 0.0017 0.0014 0.0009 0.0008 0.0014 0.0009 0.0006 0.0041 0.0019 0.0022 0.0023 0.0102 0.0011

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 63.1604 33.5595 48.4591 65.2215 51.6336 46.1399 53.076 57.0997 56.9456 73.9282
Translational Efficiency 0.8483 1.1547 0.8867 0.7943 0.8763 1.1585 0.9174 0.7271 0.8934 0.735

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1596 391 197 1001 1800 1424 1153 18 3396 1815 1350 1019

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 858.76 1224.29 1822.25 1333.47 936.04 1108.67 1077.97 1419.46 899.72 1133.58 1186.58 1334.99
Standard Deviation 107.70 200.04 224.22 205.50 190.07 162.24 189.08 177.01 161.52 177.57 326.97 205.34
Intensity Change Log 2 — 0.511618 1.085394 0.634858 — 0.244188 0.203675 0.600700 — 0.378338 0.692339 0.617145

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.007682 0.006481 0.022180 0.031139 0.005210 0.004232 0.001887 0.000629 0.006372 0.004717 0.004848 0.030600
Bud Neck 0.000509 0.000455 0.006643 0.001884 0.001437 0.000348 0.006693 0.000999 0.001001 0.000371 0.006686 0.001868
Bud Site 0.004535 0.005547 0.006252 0.057166 0.004411 0.005014 0.008966 0.009151 0.004469 0.005129 0.008570 0.056318
Cell Periphery 0.000133 0.000064 0.000204 0.000174 0.000161 0.000058 0.000186 0.000027 0.000148 0.000059 0.000189 0.000172
Cytoplasm 0.002818 0.001768 0.000856 0.059144 0.002179 0.001931 0.019754 0.011107 0.002480 0.001896 0.016996 0.058295
Cytoplasmic Foci 0.247314 0.276348 0.178844 0.266922 0.219148 0.283911 0.336216 0.359685 0.232385 0.282281 0.313251 0.268560
Eisosomes 0.000082 0.000040 0.000089 0.000053 0.000074 0.000037 0.000076 0.000008 0.000078 0.000038 0.000078 0.000052
Endoplasmic Reticulum 0.000535 0.000344 0.001898 0.000349 0.000491 0.000340 0.000603 0.000078 0.000512 0.000341 0.000792 0.000344
Endosome 0.167201 0.161356 0.175556 0.145535 0.187632 0.148819 0.275150 0.248233 0.178030 0.151520 0.260617 0.147349
Golgi 0.444541 0.511577 0.429270 0.304173 0.506446 0.509192 0.104239 0.141309 0.477353 0.509706 0.151670 0.301296
Lipid Particles 0.014750 0.003451 0.052675 0.005719 0.014274 0.006913 0.059637 0.008746 0.014498 0.006167 0.058621 0.005772
Mitochondria 0.063745 0.005952 0.001210 0.002950 0.030923 0.011000 0.005462 0.000056 0.046348 0.009912 0.004842 0.002899
Mitotic Spindle 0.004821 0.008786 0.037948 0.055363 0.002891 0.007620 0.090502 0.179777 0.003798 0.007871 0.082833 0.057561
None 0.000201 0.000015 0.000039 0.000031 0.000512 0.000275 0.003793 0.000010 0.000366 0.000219 0.003245 0.000031
Nuclear Periphery 0.000064 0.000026 0.002573 0.000077 0.000056 0.000059 0.000504 0.000115 0.000060 0.000052 0.000806 0.000078
Nuclear Periphery Foci 0.001210 0.000158 0.014810 0.000800 0.003575 0.000290 0.011335 0.002193 0.002464 0.000262 0.011842 0.000825
Nucleolus 0.000173 0.000021 0.000037 0.000032 0.001178 0.000115 0.003879 0.000024 0.000706 0.000095 0.003318 0.000032
Nucleus 0.000139 0.000019 0.000060 0.000095 0.000628 0.000978 0.005853 0.000022 0.000398 0.000771 0.005008 0.000093
Peroxisomes 0.032626 0.006954 0.005495 0.025717 0.011148 0.007156 0.038619 0.009840 0.021242 0.007112 0.033786 0.025437
Vacuole 0.003246 0.006260 0.054602 0.036800 0.004014 0.006189 0.023781 0.026018 0.003653 0.006204 0.028278 0.036609
Vacuole Periphery 0.003674 0.004379 0.008757 0.005877 0.003610 0.005523 0.002863 0.001973 0.003640 0.005276 0.003723 0.005808

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.74 -2.52 -6.48 -6.76 -1.31 0.95 3.69 5.21 4.22 1.72 1.85 1.35 -7.03 -7.53 -7.33
Bud Neck 0.30 -6.52 -9.03 -7.44 4.75 3.68 -6.28 1.16 -2.60 6.94 3.76 -8.12 -4.86 -10.15 6.53
Bud Site -0.79 -1.64 -15.94 -15.07 -15.30 -0.47 -4.20 -1.83 -1.54 0.03 -0.68 -4.72 -16.08 -15.57 -14.58
Cell Periphery 3.94 -3.37 -2.82 -7.53 1.27 2.25 -0.43 2.95 3.69 3.03 3.48 -0.87 -1.10 -10.20 0.34
Cytoplasm 1.34 2.86 -13.97 -14.32 -14.58 0.43 -7.19 -2.14 -2.21 2.09 1.23 -6.95 -14.17 -14.34 -9.35
Cytoplasmic Foci -2.94 6.27 -2.39 1.17 -7.37 -10.74 -15.01 -3.10 -1.67 -0.57 -9.93 -11.82 -5.34 2.39 5.53
Eisosomes 8.03 -0.41 6.04 -2.43 2.26 3.03 -0.30 5.42 7.03 10.17 5.77 -0.21 3.69 -3.20 4.30
Endoplasmic Reticulum 1.56 -4.43 1.69 -0.11 5.34 1.92 -1.72 6.26 4.30 9.87 2.35 -3.54 2.56 -0.09 7.02
Endosome 0.68 -0.83 4.58 2.24 3.31 7.61 -10.31 -1.44 -2.38 0.50 6.42 -11.58 7.02 1.51 15.21
Golgi -5.12 0.82 15.10 15.19 6.44 -0.37 59.92 7.81 7.86 -0.81 -4.86 48.86 20.35 22.18 -13.89
Lipid Particles 5.88 -5.31 4.48 -2.78 6.62 3.70 -10.74 1.18 -0.42 8.65 5.49 -12.00 5.93 -0.36 14.65
Mitochondria 13.81 16.35 15.68 1.66 -2.07 7.23 9.97 12.79 8.25 6.13 14.69 17.77 18.67 5.41 1.91
Mitotic Spindle -1.40 -4.05 -11.55 -9.25 -2.29 -3.02 -14.60 -2.60 -2.53 -1.29 -3.03 -14.98 -12.01 -10.85 3.10
None 1.87 1.63 1.68 -4.09 0.86 0.75 -3.12 2.68 1.13 3.55 0.65 -3.21 3.03 1.01 3.53
Nuclear Periphery 1.63 -5.14 -0.88 -6.57 5.10 -0.15 -4.82 -1.92 -1.80 4.03 0.48 -6.88 -1.74 -2.56 6.66
Nuclear Periphery Foci 1.92 -3.15 0.54 -5.89 3.24 3.60 -5.12 0.91 -1.54 5.37 4.01 -6.68 2.76 -5.10 8.00
Nucleolus 1.62 1.47 1.50 -0.91 0.21 2.82 -3.79 3.10 1.59 5.01 2.96 -4.21 3.32 1.35 5.00
Nucleus 2.63 1.81 -0.21 -4.66 -3.44 -0.54 -4.40 2.60 1.56 5.00 -0.76 -4.59 1.96 1.30 4.87
Peroxisomes 9.10 9.26 2.35 -7.47 -7.67 2.94 -11.21 0.42 -0.82 7.72 9.54 -5.70 -1.66 -8.66 3.53
Vacuole -2.49 -8.15 -14.70 -12.40 2.02 -2.89 -10.26 -3.37 -3.02 -0.18 -4.05 -12.94 -14.73 -13.42 -3.67
Vacuole Periphery -0.62 -3.94 -2.80 -1.11 2.22 -2.33 2.12 2.68 3.78 1.37 -2.37 -0.05 -3.13 -0.44 -3.02
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Member of the ChAPs family (Chs5p-Arf1p-binding proteins); members include Bch1p, Bch2p, Bud7p, and Chs6p; ChAPs family proteins form the exomer complex with Chs5p to mediate export of specific cargo proteins from the Golgi to the plasma membrane; interacts selectively with the activated, GTP-bound form of Arf1p; may interact with ribosomes; protein abundance increases and forms cytoplasmic foci in response to DNA replication stress
Localization
Cell Percentages Golgi (8%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Bch1

Bch1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Bch1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available