Standard name
Human Ortholog
Description Component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.11 0.09 0 0 0 0 0 0 0 0 0 0 0 0 0.12 0.13 0.1 0 0 0 0.05 0.05 0.06
Bud 0 0 0.07 0 0 0 0 0 0.06 0.07 0.07 0 0 0 0.05 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.09 0.05 0.08 0.05 0.06 0.15 0.05 0.08 0.09 0.09 0.05 0.06 0.05 0.08 0.08 0.1 0 0 0.05 0 0 0
Endoplasmic Reticulum 0.07 0.11 0 0 0 0 0 0 0 0 0 0.05 0.05 0.06 0.09 0 0.06 0 0 0 0 0 0
Endosome 0.07 0 0.21 0.28 0.15 0.08 0.15 0 0 0 0 0 0.11 0.07 0.12 0.22 0.18 0.11 0.12 0.14 0.1 0.08 0.07
Golgi 0.44 0.28 0.17 0 0 0 0 0 0 0 0 0.26 0.41 0.21 0.47 0.52 0.51 0.74 0.59 0.55 0.63 0.69 0.72
Mitochondria 0.75 0.69 0.56 0.67 0.8 0.85 0.66 0.91 0.9 0.87 0.88 0.81 0.52 0.74 0.12 0.12 0.1 0.08 0.16 0.16 0.14 0.1 0.06
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0.06 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0
SpindlePole 0 0 0.05 0.06 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.07 0.07 0.19 0.19 0.08 0 0.08 0.05 0.08 0 0 0 0.1 0.05 0.11 0.16 0.13 0 0.05 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 19 32 3 1 0 0 1 0 2 0 0 5 3 4 16 16 8 2 12 1 12 21 22
Bud 2 8 6 0 4 5 3 4 9 7 7 6 3 8 7 1 1 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 2 2 2 1 2 0 0 0 0 0 0
Cell Periphery 1 4 1 0 2 0 1 0 0 0 0 0 2 1 2 0 2 0 0 0 0 0 1
Cytoplasm 4 33 4 3 5 9 24 8 13 9 9 17 26 21 10 10 8 0 5 5 0 0 3
Endoplasmic Reticulum 11 41 0 0 0 1 0 5 0 0 0 17 20 23 12 4 5 0 3 0 1 3 5
Endosome 12 13 17 10 16 12 23 3 0 0 0 12 50 26 16 27 15 20 52 15 25 35 28
Golgi 74 102 14 1 0 1 5 1 1 0 0 92 179 82 63 64 42 135 264 62 168 312 282
Mitochondria 126 253 45 24 86 123 102 140 138 88 88 283 229 286 16 15 8 13 70 18 37 43 24
Nucleus 1 0 1 0 0 3 4 0 5 3 3 0 2 2 1 0 0 0 0 0 0 0 0
Nuclear Periphery 0 1 0 0 0 0 0 0 0 2 2 1 0 2 3 1 2 0 2 1 0 0 0
Nucleolus 1 0 1 0 4 0 0 0 0 1 1 1 0 2 1 2 0 0 0 0 0 0 0
Peroxisomes 0 1 1 1 6 4 9 4 0 1 1 1 3 1 0 0 0 3 5 3 14 27 14
SpindlePole 0 2 4 2 0 4 10 1 5 2 2 2 2 2 5 5 2 0 2 0 1 1 0
Vac/Vac Membrane 12 25 15 7 9 6 12 7 12 3 2 15 42 21 15 20 11 2 22 1 2 3 1
Unique Cell Count 168 368 80 36 108 144 155 154 153 101 100 351 441 384 133 123 83 183 446 114 266 454 391
Labelled Cell Count 263 515 112 49 132 168 196 176 187 117 117 452 561 481 167 165 104 183 446 114 266 454 391


Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.0 7.2 7.5 7.4 5.9 5.8 6.7 5.2 4.8 4.6 4.6 7.4 7.7 7.2 9.2 9.5 9.0 6.8 7.1 7.6
Std Deviation (1e-4) 1.0 1.2 1.4 1.9 1.3 1.4 2.1 1.3 1.3 1.2 1.2 1.0 1.2 1.2 1.8 1.9 1.9 1.1 1.1 1.3
Intensity Change (Log2) -0.02 -0.36 -0.37 -0.16 -0.54 -0.64 -0.72 -0.72 -0.03 0.03 -0.06 0.29 0.33 0.26 -0.14 -0.09 0.01

WT3RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 2.1 2.2 1.5
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 2.4 0 1.0 1.0 1.0 0 0 0 0.7 0.9 1.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.8 -1.1 -2.8 -1.2 -5.0 0 0 0 -5.7 -2.4 -4.1 -1.8 0.1 -0.5
Golgi 0 -4.5 -4.8 -3.8 -5.0 0 0 0 1.6 3.9 0.8 4.4 4.9 4.4
Mitochondria 1.1 3.4 4.8 1.4 6.2 0 0 0 4.6 -0.7 3.3 -6.9 -6.7 -6.4
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0.1 -2.1 -3.6 -2.5 -3.5 -2.5 -3.5 -3.8 -4.6 -2.4 -4.0 -1.5 -0.5 -1.0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.2678 5.4524 4.8882 4.2125 4.3259 4.686 3.9712 4.6361 4.414 3.9614 4.0987 4.237 2.6694 3.4061 3.0126 2.5226 2.6531 2.8153
Actin 0.0325 0.0175 0.0154 0.0101 0.0285 0.0063 0.0184 0.0035 0.0248 0.0255 0.0037 0.003 0.0187 0.0068 0.0028 0.0006 0.001 0.0111
Bud 0.0006 0.0014 0.0004 0.0002 0.0004 0.0002 0.0004 0.0002 0.0007 0.0002 0.0005 0.0001 0.0001 0.0004 0.0001 0.0001 0.0001 0.0002
Bud Neck 0.0015 0.0011 0.0022 0.0014 0.0177 0.0004 0.0009 0.0002 0.0012 0.0008 0.0003 0.0004 0.0008 0.0002 0.0002 0.0001 0.0001 0.0004
Bud Periphery 0.0008 0.0014 0.0004 0.0001 0.0004 0.0002 0.0004 0.0001 0.0008 0.0002 0.0015 0.0002 0.0001 0.0003 0.0001 0 0 0.0001
Bud Site 0.0029 0.0096 0.0024 0.0004 0.0012 0.0004 0.0037 0.0049 0.004 0.0013 0.0005 0.0001 0.0004 0.0006 0.0002 0.0001 0.0001 0.0002
Cell Periphery 0.0003 0.0004 0.0006 0.0001 0.0002 0.0001 0.0001 0 0.0002 0.0001 0.0001 0 0.0001 0 0 0 0 0
Cytoplasm 0.0081 0.0155 0.0061 0.0033 0.0038 0.0057 0.0125 0.0077 0.0051 0.0068 0.005 0.0031 0.0059 0.0088 0.0076 0.0068 0.0099 0.0072
Cytoplasmic Foci 0.1154 0.1356 0.0822 0.0768 0.1003 0.0648 0.0955 0.1072 0.0869 0.0848 0.0743 0.063 0.0851 0.1175 0.0923 0.0811 0.0847 0.0771
Eisosomes 0.0004 0.0002 0.0006 0 0.0002 0.0001 0.0001 0 0.0001 0.0001 0.0001 0 0.0001 0 0 0 0 0
Endoplasmic Reticulum 0.007 0.0016 0.0016 0.0009 0.0011 0.0036 0.0029 0.0007 0.0011 0.0017 0.0037 0.0011 0.0013 0.0008 0.0012 0.0009 0.0012 0.0011
Endosome 0.251 0.3068 0.2766 0.3298 0.2944 0.2502 0.232 0.2254 0.2216 0.3133 0.3382 0.1788 0.356 0.3122 0.3155 0.4573 0.3967 0.2328
Golgi 0.4051 0.4269 0.5138 0.5414 0.4382 0.5292 0.553 0.6257 0.6042 0.4731 0.4858 0.7315 0.4858 0.5301 0.554 0.4401 0.4568 0.6163
Lipid Particles 0.0562 0.016 0.0092 0.0051 0.0145 0.0265 0.0082 0.0023 0.0044 0.0338 0.008 0.0011 0.0049 0.0035 0.0018 0.0022 0.0029 0.006
Mitochondria 0.0556 0.036 0.0565 0.0216 0.0542 0.0807 0.0404 0.0155 0.0281 0.0398 0.0508 0.0142 0.0252 0.0103 0.0179 0.0039 0.0394 0.0368
None 0.0118 0.0056 0.0121 0.0001 0.0021 0.0113 0.0033 0.0007 0.0002 0.0005 0.0008 0 0.001 0.0001 0.0001 0.0001 0.0005 0.003
Nuclear Periphery 0.003 0.0004 0.0005 0.0001 0.0003 0.002 0.0047 0.0002 0.0023 0.0005 0.0112 0.0001 0.0003 0.0001 0.0001 0.0002 0.0001 0.0003
Nucleolus 0.0006 0.0005 0.0004 0 0.007 0.0003 0.0007 0.0001 0.0002 0.0009 0.0001 0 0.0001 0 0 0 0 0
Nucleus 0.0007 0.0004 0.0004 0.0001 0.0028 0.0006 0.0036 0.0001 0.0004 0.0003 0.0005 0.0001 0.0001 0 0 0 0 0.0001
Peroxisomes 0.0324 0.0166 0.013 0.0047 0.016 0.0095 0.0082 0.002 0.0057 0.0065 0.0022 0.0011 0.0056 0.0055 0.0028 0.0011 0.0014 0.0037
Punctate Nuclear 0.0079 0.0005 0.0012 0.0001 0.0097 0.0021 0.0024 0.0015 0.0009 0.0022 0.0004 0 0.0035 0.0001 0.0001 0.0001 0.0001 0.0002
Vacuole 0.0036 0.0039 0.0025 0.0013 0.0041 0.0031 0.0039 0.0008 0.0046 0.0046 0.0042 0.0007 0.0024 0.0013 0.0015 0.002 0.0023 0.0014
Vacuole Periphery 0.0027 0.0022 0.0021 0.0023 0.003 0.0028 0.0047 0.001 0.0027 0.003 0.0082 0.0013 0.0027 0.0015 0.0017 0.003 0.0025 0.002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 22.3308 18.0053 13.9416 22.3045 21.005 18.8175 24.1416 26.1771 21.6118 24.7686
Translational Efficiency 0.9779 1.0509 1.1257 0.7193 0.7153 0.9956 0.8475 0.5628 0.7984 0.8395

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1592 1626 1288 1040 1355 1613 1109 1488 2947 3239 2397 2528

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 817.44 943.27 985.58 981.57 844.96 911.80 956.32 1041.49 830.09 927.60 972.04 1016.84
Standard Deviation 95.19 145.02 141.01 127.47 109.06 124.57 152.66 124.04 102.73 136.14 147.24 128.88
Intensity Change Log 2 0.206558 0.269860 0.263978 0.109834 0.178610 0.301694 0.158206 0.224201 0.283272

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002129 0.001407 0.001804 0.006428 0.002391 0.002880 0.000748 0.005908 0.002249 0.002141 0.001316 0.006122
Bud Neck 0.000141 0.000097 0.001682 0.000571 0.000126 0.000137 0.002008 0.000364 0.000134 0.000117 0.001833 0.000449
Bud Site 0.001198 0.001240 0.006782 0.011815 0.001403 0.001113 0.004685 0.008159 0.001292 0.001177 0.005812 0.009663
Cell Periphery 0.000077 0.000044 0.000064 0.000077 0.000064 0.000068 0.000057 0.000055 0.000071 0.000056 0.000061 0.000064
Cytoplasm 0.000502 0.001354 0.003032 0.006119 0.000823 0.000568 0.004526 0.003675 0.000649 0.000963 0.003723 0.004680
Cytoplasmic Foci 0.154787 0.167312 0.220469 0.236373 0.147015 0.144293 0.210935 0.200936 0.151214 0.155849 0.216058 0.215514
Eisosomes 0.000062 0.000025 0.000032 0.000040 0.000072 0.000042 0.000035 0.000036 0.000067 0.000033 0.000033 0.000038
Endoplasmic Reticulum 0.000283 0.000198 0.002343 0.000558 0.000374 0.000443 0.000959 0.000605 0.000325 0.000320 0.001703 0.000586
Endosome 0.179276 0.128788 0.264706 0.204120 0.135542 0.166858 0.287203 0.193133 0.159168 0.147747 0.275115 0.197653
Golgi 0.593844 0.653853 0.242463 0.442996 0.657447 0.629749 0.274522 0.511069 0.623088 0.641850 0.257295 0.483065
Lipid Particles 0.005882 0.003872 0.022813 0.002267 0.004513 0.002129 0.044817 0.000973 0.005253 0.003004 0.032994 0.001505
Mitochondria 0.048972 0.021626 0.010135 0.007662 0.032317 0.032613 0.015466 0.007987 0.041315 0.027098 0.012601 0.007853
Mitotic Spindle 0.001240 0.003131 0.101117 0.032514 0.002522 0.002162 0.057817 0.015506 0.001829 0.002648 0.081083 0.022503
None 0.000033 0.000072 0.000170 0.000020 0.000034 0.000043 0.001504 0.000017 0.000033 0.000057 0.000787 0.000018
Nuclear Periphery 0.000028 0.000042 0.002276 0.000075 0.000031 0.000034 0.001395 0.000084 0.000029 0.000038 0.001868 0.000080
Nuclear Periphery Foci 0.000123 0.000214 0.013259 0.000584 0.000103 0.000128 0.008523 0.000451 0.000114 0.000171 0.011068 0.000506
Nucleolus 0.000018 0.000009 0.000935 0.000021 0.000034 0.000116 0.001977 0.000017 0.000025 0.000062 0.001417 0.000019
Nucleus 0.000021 0.000018 0.000872 0.000041 0.000074 0.000344 0.001301 0.000036 0.000046 0.000180 0.001070 0.000038
Peroxisomes 0.002860 0.001319 0.005452 0.005412 0.003314 0.002108 0.008498 0.003669 0.003069 0.001712 0.006861 0.004386
Vacuole 0.002879 0.005823 0.076701 0.031501 0.003867 0.005915 0.052993 0.032628 0.003333 0.005869 0.065732 0.032165
Vacuole Periphery 0.005643 0.009554 0.022892 0.010805 0.007934 0.008258 0.020031 0.014693 0.006696 0.008909 0.021569 0.013093

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.16 0.50 -3.58 -4.23 -3.97 -0.45 2.29 -2.69 -2.17 -4.53 0.17 2.02 -4.34 -4.30 -5.80
Bud Neck 1.05 -8.97 -5.28 -5.79 5.92 -0.24 -5.03 -4.26 -4.49 4.34 0.57 -8.69 -6.78 -7.36 6.90
Bud Site -0.13 -5.61 -7.18 -7.45 -3.10 0.60 -4.47 -6.47 -7.38 -2.84 0.26 -7.14 -9.65 -10.42 -3.87
Cell Periphery 3.02 0.86 -0.06 -2.79 -0.85 -0.22 0.82 1.35 0.69 0.49 1.36 1.15 0.84 -0.79 -0.20
Cytoplasm -1.60 -6.15 -5.84 -4.27 -2.66 1.36 -4.31 -6.29 -7.25 0.89 -1.18 -6.92 -8.46 -6.77 -1.25
Cytoplasmic Foci -2.86 -11.80 -13.87 -11.71 -2.52 0.70 -11.61 -11.31 -12.23 1.52 -1.57 -16.50 -17.24 -16.18 -0.10
Eisosomes 10.13 8.39 4.70 -3.89 -2.00 3.23 4.05 3.83 1.23 -0.04 6.99 7.15 5.71 -1.37 -1.26
Endoplasmic Reticulum 2.55 -8.30 -3.70 -5.03 6.95 -0.37 -4.97 -1.53 -0.68 2.00 0.05 -9.52 -2.83 -2.08 6.67
Endosome 10.75 -12.31 -3.53 -11.53 7.29 -6.49 -20.14 -10.63 -4.75 11.68 3.34 -22.67 -8.89 -11.94 13.65
Golgi -8.04 42.22 15.37 21.58 -18.81 3.66 41.47 16.79 13.90 -23.37 -3.48 58.81 21.42 24.67 -31.06
Lipid Particles 1.47 -6.85 3.45 1.49 8.86 1.98 -9.81 3.09 2.52 11.06 2.48 -11.91 4.91 2.61 14.15
Mitochondria 7.45 11.76 12.56 6.39 1.64 -0.08 5.39 8.55 9.44 3.79 5.48 12.49 15.11 11.27 3.87
Mitotic Spindle -2.05 -17.36 -8.43 -7.84 9.91 0.44 -11.61 -6.38 -6.70 8.28 -1.39 -20.75 -10.66 -10.17 13.67
None -0.90 -3.14 2.51 1.13 3.36 -0.58 -1.67 2.83 1.22 1.69 -1.06 -1.90 3.97 1.55 1.94
Nuclear Periphery -1.37 -7.70 -5.53 -2.93 7.53 -0.42 -5.66 -4.03 -3.82 5.43 -1.33 -9.54 -6.22 -4.63 9.27
Nuclear Periphery Foci -0.90 -10.08 -4.55 -2.80 9.69 -0.68 -6.91 -3.56 -3.24 6.62 -1.06 -12.18 -5.55 -3.99 11.71
Nucleolus 0.85 -3.58 -0.60 -1.17 3.54 -0.90 -5.05 0.60 1.05 5.10 -0.84 -6.14 0.21 0.91 6.16
Nucleus 0.30 -2.87 -2.51 -2.74 2.81 -0.89 -3.74 0.67 0.98 3.89 -0.89 -4.37 0.12 0.91 4.39
Peroxisomes 3.74 -3.84 -3.12 -4.89 -0.12 1.75 -4.91 -0.43 -2.31 4.56 3.51 -6.23 -2.34 -5.11 3.41
Vacuole -6.22 -22.67 -13.70 -12.17 11.49 -3.30 -16.22 -14.95 -13.62 5.75 -6.55 -27.68 -20.35 -18.28 12.56
Vacuole Periphery -4.88 -12.37 -4.96 -1.04 7.37 -0.34 -7.14 -5.48 -5.50 2.89 -3.59 -13.72 -7.88 -4.96 6.87
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
Localization
Cell Percentages Golgi (17%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Cog6

Cog6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cog6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available