Standard name
Description Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0.07 0 0.05 0 0 0 0 0 0 0 0.09 0.08 0.14 0.09 0.07 0.1 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.12 0.05 0.07 0.15 0.14 0.13 0.17 0 0 0.05 0.05 0 0.09 0 0 0 0 0 0
Nucleus 0.94 0.95 0.87 0.94 0.84 0.81 0.78 0.73 0.73 0.74 0.74 0.71 0.82 0.8 0.7 0.84 0.88 0.82 0.91 0.92 0.9 0.84 0.79 0.64
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.08 0.09 0.11 0.14 0.23 0.42 0.34 0.38 0.54 0.61 0.64 0.53 0.18 0.32 0.3 0.06 0 0.07 0 0 0 0.09 0.06 0.09
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.13 0.2
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1
Bud Neck 0 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 2 0 1 1 0 3 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 3 7 11 6 14 8 17 21 9 4 3 8 9 15 20 34 19 22 2 2 0 0 0 1
Endoplasmic Reticulum 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 5 3 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 1 0 0 0 0 0 1 1 0 3 0 1 0 0 0 0 0 0
Golgi 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Mitochondria 2 0 2 1 7 41 20 33 53 44 21 36 2 7 7 19 7 20 0 2 0 0 0 0
Nucleus 150 209 147 173 216 279 317 351 252 230 115 151 81 149 99 318 234 175 154 205 149 55 117 76
Nuclear Periphery 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0
Nucleolus 13 20 19 25 59 145 138 184 186 189 100 113 18 60 43 23 10 14 4 2 7 5 8 10
Peroxisomes 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 0 1 0 0 0 0 0 0
Vac/Vac Membrane 3 3 3 1 2 2 1 3 3 0 0 3 3 2 2 9 7 7 5 3 7 1 19 23
Unique Cell Count 159 220 169 185 257 344 405 481 347 312 156 213 99 187 141 380 266 213 170 224 167 66 149 119
Labelled Cell Count 173 241 182 207 298 475 497 593 504 468 239 314 115 236 173 409 282 245 170 224 167 66 149 119


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 54.6 64.6 43.2 44.0 42.2 36.6 34.8 35.3 33.8 31.1 30.4 30.4 62.2 63.6 56.6 53.8 63.1 63.1 50.5 50.9 53.8
Std Deviation (1e-4) 15.5 25.6 18.3 16.2 18.1 13.5 18.3 15.2 14.0 11.4 11.6 15.0 29.7 26.8 31.0 24.1 26.5 27.7 18.0 19.6 20.9
Intensity Change (Log2) 0.03 -0.03 -0.24 -0.31 -0.29 -0.35 -0.47 -0.51 -0.51 0.53 0.56 0.39 0.32 0.55 0.55 0.23 0.24 0.32


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.4 -0.5 -2.4 -1.2 -1.1 -2.2 -3.1 -2.0 -1.2 0.8 0.5 2.2 1.0 0.3 1.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 4.1 2.1 2.8 4.9 4.6 4.3 5.1 0 0 0 2.2 0 3.4
Nucleus 2.1 -0.8 -1.7 -2.4 -3.7 -3.7 -3.4 -3.0 -3.8 -1.1 -1.8 -3.6 -1.0 0.3 -1.3
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.6 3.1 7.1 5.6 6.5 9.2 10.4 9.9 8.5 1.6 4.7 4.2 -2.1 -3.0 -1.6
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Hrp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available