Standard name | |
---|---|
Human Ortholog | |
Description | Ubiquitin-binding protein; functions as ubiquitin-Atg8p adaptor in ubiquitin-dependent autophagy; serves as proteaphagy receptor for inactivated 26S proteasomes; contains CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; CUE5 has a paralog, DON1, that arose from the whole genome duplication; human TOLLIP is a functional CUE-domain homolog, can complement yeast null mutant, rescuing hypersensitivity of cue5 null mutant cells to Htt-96Q |
ensLOC | DeepLoc | |||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
Cortical Patches | 7 | 6 | 55 | 17 | 23 | 35 | 41 | 23 | 25 | 47 | 24 | 31 | 9 | 9 | 5 | 4 | 8 | 10 | 3 | 5 | 31 | 4 | 9 | 12 |
Bud | 0 | 0 | 2 | 2 | 6 | 4 | 8 | 8 | 1 | 12 | 6 | 10 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 3 | 0 |
Bud Neck | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 2 | 0 | 0 | 0 |
Bud Site | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | – | – | – | – | – |
Cell Periphery | 1 | 1 | 26 | 4 | 5 | 11 | 20 | 19 | 23 | 29 | 14 | 19 | 3 | 7 | 10 | 6 | 14 | 6 | 0 | 0 | 10 | 0 | 0 | 0 |
Cytoplasm | 71 | 110 | 117 | 76 | 150 | 142 | 162 | 130 | 74 | 119 | 82 | 96 | 93 | 71 | 129 | 148 | 145 | 113 | 53 | 73 | 93 | 21 | 36 | 29 |
Endoplasmic Reticulum | 7 | 15 | 75 | 32 | 52 | 68 | 87 | 64 | 57 | 96 | 33 | 50 | 36 | 23 | 18 | 6 | 9 | 9 | 15 | 22 | 70 | 12 | 32 | 32 |
Endosome | 1 | 0 | 1 | 0 | 3 | 2 | 0 | 2 | 3 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 2 | 8 | 5 | 3 | 3 |
Golgi | 2 | 1 | 50 | 29 | 18 | 26 | 26 | 16 | 21 | 12 | 13 | 13 | 2 | 6 | 6 | 14 | 19 | 7 | 13 | 13 | 75 | 8 | 21 | 21 |
Mitochondria | 11 | 3 | 12 | 17 | 25 | 98 | 179 | 150 | 96 | 180 | 154 | 174 | 0 | 0 | 0 | 0 | 8 | 1 | 3 | 2 | 19 | 3 | 3 | 4 |
Nucleus | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nuclear Periphery | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Nucleolus | 2 | 1 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peroxisomes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
SpindlePole | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |
Vac/Vac Membrane | 0 | 0 | 3 | 1 | 1 | 1 | 5 | 9 | 6 | 10 | 4 | 10 | 1 | 1 | 0 | 3 | 7 | 12 | 2 | 6 | 1 | 6 | 4 | 4 |
Unique Cell Count | 91 | 127 | 268 | 140 | 240 | 290 | 399 | 326 | 226 | 367 | 262 | 313 | 132 | 99 | 151 | 169 | 184 | 144 | 102 | 131 | 315 | 70 | 116 | 112 |
Labelled Cell Count | 103 | 138 | 343 | 178 | 285 | 387 | 531 | 422 | 306 | 505 | 333 | 409 | 144 | 118 | 170 | 181 | 215 | 160 | 102 | 131 | 315 | 70 | 116 | 112 |
Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean Cell GFP Intensity (1e-4) | 11.5 | 15.1 | 13.6 | 12.5 | 12.6 | 11.9 | 11.2 | 11.4 | 11.5 | 11.0 | 10.0 | 10.5 | 15.4 | 15.3 | 15.1 | 25.6 | 22.5 | 22.8 | – | 16.4 | 16.1 |
Std Deviation (1e-4) | 2.5 | 2.7 | 1.8 | 2.0 | 1.8 | 1.8 | 2.1 | 2.2 | 2.4 | 2.4 | 2.5 | 2.5 | 2.4 | 2.3 | 2.5 | 7.2 | 6.5 | 6.7 | – | 2.3 | 2.9 |
Intensity Change (Log2) | – | – | – | -0.12 | -0.11 | -0.19 | -0.27 | -0.25 | -0.23 | -0.3 | -0.43 | -0.37 | 0.18 | 0.17 | 0.15 | 0.92 | 0.73 | 0.75 | – | 0.28 | 0.25 |
Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cortical Patches | -2.1 | -3.4 | -2.7 | -3.7 | -4.8 | -2.8 | -2.6 | -3.7 | -3.6 | -3.5 | -2.6 | -4.8 | -5.4 | -4.9 | -3.6 |
Bud | 0 | 0 | 0 | 0 | 0 | 0 | 2.1 | 0 | 2.1 | 0 | 0 | 0 | 0 | 0 | 0 |
Bud Neck | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bud Site | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cell Periphery | -2.5 | -3.6 | -2.8 | -2.3 | -1.8 | 0.2 | -0.8 | -1.9 | -1.6 | -2.7 | -0.8 | -1.1 | -2.4 | -0.8 | -2.0 |
Cytoplasm | 2.0 | 4.2 | 1.3 | -0.8 | -0.9 | -2.5 | -2.9 | -2.9 | -3.2 | 5.0 | 4.8 | 8.3 | 9.2 | 7.4 | 6.8 |
Endoplasmic Reticulum | -1.1 | -1.6 | -1.2 | -1.8 | -2.4 | -0.7 | -0.5 | -4.4 | -3.5 | -0.1 | -0.9 | -3.8 | -6.4 | -6.2 | -5.2 |
Endosome | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Golgi | 0.5 | -3.7 | -3.3 | -4.8 | -5.3 | -3.0 | -6.5 | -4.9 | -5.6 | -4.8 | -3.0 | -4.2 | -3.0 | -2.4 | -3.9 |
Mitochondria | 2.9 | 2.6 | 8.7 | 11.3 | 11.3 | 10.2 | 12.1 | 13.5 | 13.2 | 0 | 0 | 0 | 0 | -0.1 | 0 |
Nucleus | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nuclear Periphery | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nucleolus | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peroxisomes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
SpindlePole | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vacuole | 0 | 0 | 0 | 0 | 1.4 | 0 | 1.4 | 0 | 1.7 | 0 | 0 | 0 | 0 | 0 | 3.7 |
R1 | R2 | R3 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
Concentration | 9.4555 | 11.2564 | 10.343 | 9.5178 | 8.7185 | 10.283 | 8.5897 | 12.084 | 11.0527 | 10.0467 | 9.6408 | 10.7956 | 9.0941 | 11.9135 | 10.2953 | 9.5871 | 8.8725 | 10.3226 |
Actin | 0.0623 | 0.0195 | 0.0431 | 0.1134 | 0.0665 | 0.0415 | 0.0465 | 0.0137 | 0.0243 | 0.0143 | 0.0792 | 0.0723 | 0.0325 | 0.0299 | 0.0665 | 0.0359 | 0.1409 | 0.0525 |
Bud | 0.0024 | 0.0026 | 0.0025 | 0.0036 | 0.0023 | 0.0017 | 0.0012 | 0.002 | 0.0021 | 0.0014 | 0.0016 | 0.0014 | 0.0022 | 0.003 | 0.0047 | 0.006 | 0.0013 | 0.001 |
Bud Neck | 0.0018 | 0.0009 | 0.0015 | 0.0014 | 0.0026 | 0.0096 | 0.0016 | 0.0007 | 0.0022 | 0.0024 | 0.0015 | 0.0205 | 0.0016 | 0.0008 | 0.0032 | 0.0024 | 0.0021 | 0.0105 |
Bud Periphery | 0.0027 | 0.0013 | 0.0014 | 0.0043 | 0.0023 | 0.0021 | 0.0009 | 0.0007 | 0.0014 | 0.0011 | 0.0011 | 0.0025 | 0.0024 | 0.0009 | 0.0021 | 0.0037 | 0.0007 | 0.0009 |
Bud Site | 0.003 | 0.0065 | 0.0026 | 0.0033 | 0.002 | 0.0008 | 0.004 | 0.0062 | 0.0073 | 0.0011 | 0.0008 | 0.0011 | 0.0021 | 0.0066 | 0.0087 | 0.0008 | 0.0014 | 0.0005 |
Cell Periphery | 0.0018 | 0.0004 | 0.0006 | 0.001 | 0.0008 | 0.0008 | 0.002 | 0.0005 | 0.0007 | 0.0005 | 0.0004 | 0.0016 | 0.0011 | 0.0007 | 0.0007 | 0.0006 | 0.0004 | 0.0005 |
Cytoplasm | 0.2766 | 0.3666 | 0.3566 | 0.2642 | 0.1678 | 0.1954 | 0.3399 | 0.5838 | 0.5287 | 0.4296 | 0.3508 | 0.3157 | 0.3439 | 0.4867 | 0.4012 | 0.3599 | 0.1035 | 0.202 |
Cytoplasmic Foci | 0.0717 | 0.0987 | 0.0756 | 0.0579 | 0.1013 | 0.0746 | 0.0765 | 0.0692 | 0.0804 | 0.1399 | 0.0869 | 0.07 | 0.0708 | 0.079 | 0.0829 | 0.0908 | 0.0821 | 0.0676 |
Eisosomes | 0.0004 | 0.0001 | 0.0001 | 0.0014 | 0.0004 | 0.0005 | 0.0005 | 0 | 0.0001 | 0.0001 | 0.0001 | 0.0007 | 0.0003 | 0.0001 | 0.0005 | 0.0002 | 0.0002 | 0.0002 |
Endoplasmic Reticulum | 0.0427 | 0.0111 | 0.0133 | 0.0069 | 0.0132 | 0.0182 | 0.0241 | 0.0132 | 0.0254 | 0.0226 | 0.0156 | 0.0329 | 0.0646 | 0.0113 | 0.0168 | 0.0129 | 0.0111 | 0.0408 |
Endosome | 0.2034 | 0.2245 | 0.2653 | 0.2635 | 0.2446 | 0.222 | 0.2519 | 0.1913 | 0.1927 | 0.23 | 0.1772 | 0.1838 | 0.2054 | 0.1911 | 0.2155 | 0.3267 | 0.1711 | 0.2393 |
Golgi | 0.2713 | 0.2446 | 0.2033 | 0.2285 | 0.3538 | 0.3763 | 0.168 | 0.1033 | 0.0922 | 0.1255 | 0.1813 | 0.2464 | 0.2062 | 0.1748 | 0.1457 | 0.1154 | 0.4466 | 0.3408 |
Lipid Particles | 0.0011 | 0.0006 | 0.0022 | 0.0006 | 0.0007 | 0.0005 | 0.0192 | 0.0016 | 0.0039 | 0.0013 | 0.0036 | 0.0026 | 0.0042 | 0.0004 | 0.0073 | 0.0058 | 0.0037 | 0.0016 |
Mitochondria | 0.0435 | 0.0134 | 0.0183 | 0.0315 | 0.0299 | 0.0477 | 0.026 | 0.0043 | 0.0142 | 0.006 | 0.056 | 0.0388 | 0.0266 | 0.0072 | 0.02 | 0.006 | 0.0102 | 0.0291 |
None | 0.0012 | 0.0006 | 0.0007 | 0.0005 | 0.0015 | 0.0005 | 0.0053 | 0.0005 | 0.0021 | 0.0006 | 0.0006 | 0.0009 | 0.0023 | 0.0008 | 0.0017 | 0.0009 | 0.0003 | 0.0008 |
Nuclear Periphery | 0.002 | 0.0006 | 0.0007 | 0.0008 | 0.0009 | 0.0005 | 0.0058 | 0.0007 | 0.0013 | 0.0008 | 0.0005 | 0.001 | 0.0103 | 0.0005 | 0.0028 | 0.0025 | 0.0003 | 0.0039 |
Nucleolus | 0 | 0 | 0 | 0 | 0 | 0 | 0.0004 | 0 | 0.0001 | 0 | 0 | 0.0001 | 0.0002 | 0.0001 | 0.0002 | 0.0001 | 0 | 0.0001 |
Nucleus | 0.0006 | 0.0004 | 0.0004 | 0.0004 | 0.0004 | 0.0003 | 0.0056 | 0.0004 | 0.0007 | 0.0005 | 0.0003 | 0.0005 | 0.0039 | 0.0005 | 0.001 | 0.0006 | 0.0001 | 0.0005 |
Peroxisomes | 0.0006 | 0.0013 | 0.0014 | 0.0008 | 0.001 | 0.0007 | 0.009 | 0.0007 | 0.003 | 0.0052 | 0.0328 | 0.0021 | 0.0015 | 0.0006 | 0.0042 | 0.0017 | 0.0202 | 0.0011 |
Punctate Nuclear | 0.0002 | 0.0001 | 0.0003 | 0.0002 | 0.0001 | 0.0001 | 0.0028 | 0.0001 | 0.0046 | 0.0079 | 0.0033 | 0.0003 | 0.0017 | 0.0002 | 0.001 | 0.001 | 0.0005 | 0.0011 |
Vacuole | 0.0068 | 0.0038 | 0.0063 | 0.0073 | 0.0045 | 0.0032 | 0.0055 | 0.0048 | 0.0082 | 0.0059 | 0.0033 | 0.0026 | 0.0128 | 0.0031 | 0.0094 | 0.0192 | 0.0017 | 0.0024 |
Vacuole Periphery | 0.004 | 0.0023 | 0.0038 | 0.0085 | 0.0033 | 0.0032 | 0.0035 | 0.0021 | 0.0045 | 0.0033 | 0.003 | 0.0025 | 0.0036 | 0.0019 | 0.0038 | 0.0067 | 0.0014 | 0.0029 |
R1 | R2 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
Gene Expression | 56.2415 | 35.9118 | 55.6649 | 67.3306 | 59.0301 | 47.2881 | 55.0707 | 67.2582 | 74.1963 | 58.0455 |
Translational Efficiency | 1.7573 | 2.3429 | 1.756 | 1.7313 | 1.6317 | 2.2017 | 1.4368 | 1.6927 | 1.6778 | 1.5335 |
Dataset | Hit |
---|---|
Protein Concentration | ✘ |
Protein Localization | ✔ |
Gene Expression | ✘ |
Translational Efficiency | ✘ |
R1 | R2 | R1 & R2 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
1120 | 314 | 2664 | 1549 | 1957 | 1422 | 145 | 1443 | 3077 | 1736 | 2809 | 2992 |
R1 | R2 | R1 & R2 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
Mean | 1138.54 | 1424.87 | 1531.11 | 1574.02 | 1235.20 | 1302.95 | 1661.98 | 1548.16 | 1200.02 | 1325.00 | 1537.87 | 1561.55 |
Standard Deviation | 192.35 | 229.88 | 213.40 | 276.63 | 193.41 | 209.61 | 236.77 | 259.30 | 198.55 | 218.52 | 216.62 | 268.72 |
Intensity Change Log 2 | — | 0.323645 | 0.427393 | 0.467269 | — | 0.077037 | 0.428158 | 0.325810 | — | 0.200587 | 0.427791 | 0.395392 |
R1 | R2 | R1 & R2 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
Actin | 0.009416 | 0.011650 | 0.024349 | 0.045936 | 0.007514 | 0.006791 | 0.043560 | 0.025068 | 0.008207 | 0.007670 | 0.025340 | 0.035872 |
Bud Neck | 0.000291 | 0.000565 | 0.000656 | 0.004792 | 0.000313 | 0.000510 | 0.006281 | 0.003350 | 0.000305 | 0.000520 | 0.000946 | 0.004097 |
Bud Site | 0.025602 | 0.046782 | 0.045021 | 0.185659* | 0.020136 | 0.033739 | 0.087443 | 0.131445* | 0.022125 | 0.036099 | 0.047210 | 0.159512* |
Cell Periphery | 0.003246 | 0.006216 | 0.003910 | 0.054715 | 0.001427 | 0.001395 | 0.009781 | 0.013106 | 0.002089 | 0.002267 | 0.004213 | 0.034647 |
Cytoplasm | 0.025148 | 0.046486 | 0.069307 | 0.290700* | 0.025949 | 0.045179 | 0.049516 | 0.227964* | 0.025657 | 0.045416 | 0.068285 | 0.260443* |
Cytoplasmic Foci | 0.507747* | 0.430925* | 0.272760* | 0.093779 | 0.439978* | 0.484795* | 0.156361 | 0.156855 | 0.464645* | 0.475051* | 0.266751* | 0.124200 |
Eisosomes | 0.000301 | 0.000217 | 0.000485 | 0.000684 | 0.000164 | 0.000149 | 0.000404 | 0.000257 | 0.000214 | 0.000161 | 0.000481 | 0.000478 |
Endoplasmic Reticulum | 0.019536 | 0.030639 | 0.019212 | 0.024284 | 0.021962 | 0.013864 | 0.063310 | 0.009957 | 0.021079 | 0.016898 | 0.021488 | 0.017375 |
Endosome | 0.066098 | 0.061208 | 0.060219 | 0.030455 | 0.056417 | 0.056415 | 0.192327 | 0.063484 | 0.059941 | 0.057282 | 0.067038 | 0.046384 |
Golgi | 0.299710* | 0.313781* | 0.420468* | 0.128843* | 0.377133* | 0.300313* | 0.220735* | 0.226485* | 0.348952* | 0.302749* | 0.410158* | 0.175934* |
Lipid Particles | 0.002691 | 0.011862 | 0.019582 | 0.084259 | 0.002867 | 0.002487 | 0.019800 | 0.041853 | 0.002803 | 0.004183 | 0.019594 | 0.063807 |
Mitochondria | 0.005850 | 0.001909 | 0.007373 | 0.004051 | 0.007525 | 0.004412 | 0.000806 | 0.002567 | 0.006915 | 0.003959 | 0.007034 | 0.003336 |
Mitotic Spindle | 0.000357 | 0.000750 | 0.003116 | 0.001980 | 0.001109 | 0.002077 | 0.007853 | 0.008142 | 0.000835 | 0.001837 | 0.003361 | 0.004952 |
None | 0.000916 | 0.000079 | 0.000172 | 0.000340 | 0.000182 | 0.000144 | 0.000050 | 0.000250 | 0.000449 | 0.000132 | 0.000166 | 0.000297 |
Nuclear Periphery | 0.000027 | 0.000053 | 0.000054 | 0.000113 | 0.000029 | 0.000030 | 0.000326 | 0.000060 | 0.000029 | 0.000034 | 0.000068 | 0.000087 |
Nuclear Periphery Foci | 0.000604 | 0.000553 | 0.000908 | 0.001722 | 0.000485 | 0.000549 | 0.007051 | 0.001965 | 0.000528 | 0.000550 | 0.001225 | 0.001839 |
Nucleolus | 0.000207 | 0.000006 | 0.000010 | 0.000049 | 0.000012 | 0.000014 | 0.000028 | 0.000045 | 0.000083 | 0.000012 | 0.000011 | 0.000047 |
Nucleus | 0.000118 | 0.000079 | 0.000140 | 0.000988 | 0.000070 | 0.001291 | 0.000423 | 0.000968 | 0.000088 | 0.001072 | 0.000154 | 0.000978 |
Peroxisomes | 0.002144 | 0.001799 | 0.003813 | 0.006808 | 0.000861 | 0.001092 | 0.003536 | 0.004029 | 0.001328 | 0.001220 | 0.003799 | 0.005468 |
Vacuole | 0.005112 | 0.011051 | 0.022987 | 0.026082 | 0.008185 | 0.014321 | 0.111874 | 0.061905 | 0.007067 | 0.013730 | 0.027575 | 0.043359 |
Vacuole Periphery | 0.024880 | 0.023391 | 0.025459 | 0.013760 | 0.027683 | 0.030434 | 0.018535 | 0.020245 | 0.026663 | 0.029160 | 0.025102 | 0.016888 |
R1 | R2 | R1 & R2 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
Actin | -0.56 | -6.38 | -11.64 | -7.53 | -6.75 | 0.45 | -3.48 | -7.30 | -7.31 | 1.79 | 0.36 | -8.97 | -14.12 | -13.23 | -4.20 |
Bud Neck | -2.85 | -6.62 | -17.85 | -15.94 | -16.26 | -1.57 | -6.22 | -15.94 | -14.02 | 2.96 | -2.22 | -7.67 | -23.37 | -20.26 | -18.57 |
Bud Site | -4.03 | -7.32 | -28.90* | -19.64 | -25.71* | -5.10 | -6.15 | -22.90 | -18.60 | -3.60 | -5.88 | -12.06 | -37.11 | -29.97 | -28.22* |
Cell Periphery | -2.34 | -1.35 | -16.55 | -14.63 | -16.43 | 0.11 | -2.72 | -8.30 | -8.26 | -0.90 | -0.52 | -6.13 | -18.25 | -18.00 | -16.90 |
Cytoplasm | -3.53 | -13.39 | -33.00 | -25.42 | -26.97 | -6.34 | -2.29 | -26.85 | -23.64 | -13.99 | -7.43 | -15.04 | -42.37 | -36.73 | -32.39 |
Cytoplasmic Foci | 5.58 | 30.16 | 54.71 | 27.39 | 36.77* | -5.53 | 21.82 | 42.56 | 45.83 | 0.10 | -1.50 | 35.45 | 68.21 | 58.85 | 32.48* |
Eisosomes | 1.31 | -3.50 | -6.03 | -6.50 | -3.21 | 0.58 | -2.68 | -2.26 | -2.43 | 1.62 | 2.00 | -7.11 | -7.36 | -8.42 | 0.23 |
Endoplasmic Reticulum | -2.18 | 0.13 | -1.89 | 1.30 | -2.31 | 4.06 | -3.66 | 7.12 | 2.61 | 4.79 | 2.33 | -0.26 | 2.71 | -0.10 | 2.82 |
Endosome | 1.25 | 2.37 | 14.69 | 9.05 | 19.12 | 0.00 | -10.45 | -2.25 | -2.24 | 9.96 | 1.41 | -3.82 | 8.38 | 6.44 | 12.00 |
Golgi | -1.09 | -15.27 | 22.29 | 15.21 | 43.94* | 9.76 | 8.44 | 18.81 | 9.53 | -0.03 | 7.02 | -9.55 | 30.63 | 20.36 | 38.49* |
Lipid Particles | -4.23 | -14.06 | -21.95 | -16.90 | -16.64 | 0.74 | -5.73 | -15.24 | -15.27 | -5.60 | -2.39 | -15.03 | -26.35 | -25.21 | -17.26 |
Mitochondria | 4.85 | -1.60 | 2.29 | -3.44 | 4.41 | 3.23 | 8.33 | 6.87 | 2.42 | -2.78 | 3.87 | -0.12 | 6.57 | 1.06 | 5.68 |
Mitotic Spindle | -2.55 | -5.73 | -10.44 | -5.92 | 2.28 | -1.38 | -2.90 | -5.66 | -4.39 | -0.28 | -1.74 | -5.28 | -6.69 | -3.90 | -2.24 |
None | 1.03 | 0.92 | 0.71 | -14.02 | -9.46 | 0.54 | 6.11 | -1.08 | -1.19 | -2.75 | 1.05 | 0.96 | 0.48 | -2.57 | -3.60 |
Nuclear Periphery | -0.83 | -2.62 | -3.40 | -1.61 | -2.33 | -0.18 | -2.49 | -7.88 | -4.79 | 2.20 | -0.75 | -4.25 | -4.71 | -3.82 | -1.29 |
Nuclear Periphery Foci | 0.15 | -0.91 | -3.18 | -5.60 | -5.22 | -0.25 | -3.28 | -5.01 | -4.00 | 2.47 | -0.08 | -3.65 | -6.55 | -5.38 | -3.08 |
Nucleolus | 1.01 | 1.00 | 0.81 | -12.00 | -11.47 | 0.00 | -0.91 | -3.01 | -5.20 | -1.64 | 0.99 | 1.02 | 0.52 | -7.73 | -12.72 |
Nucleus | 0.80 | -0.43 | -11.36 | -14.52 | -13.65 | -1.50 | -3.04 | -4.45 | 0.01 | -2.77 | -1.48 | -3.21 | -7.94 | -0.16 | -7.51 |
Peroxisomes | 0.81 | -3.56 | -7.58 | -8.59 | -4.93 | -1.55 | -3.88 | -11.38 | -10.18 | -0.61 | 0.64 | -7.42 | -12.78 | -13.60 | -3.82 |
Vacuole | -3.53 | -12.89 | -13.05 | -7.12 | -1.85 | -4.38 | -6.50 | -17.18 | -14.73 | 2.90 | -5.81 | -12.96 | -20.53 | -15.30 | -7.54 |
Vacuole Periphery | 0.48 | -0.27 | 5.30 | 3.82 | 9.20 | -1.23 | 2.82 | 4.28 | 5.33 | -0.42 | -1.34 | 1.02 | 7.37 | 7.90 | 7.29 |