Standard name
Human Ortholog
Description Alpha-1,2-mannosyltransferase; involved in O- and N-linked protein glycosylation; type II membrane protein; member of the KRE2/MNT1 mannosyltransferase family; relocalizes from vacuole to cytoplasm upon DNA replication stress
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.11 0.27 0.31 0.52 0.39 0.42 0.48 0.44 0.53 0.5 0.59 0.61 0.57 0.75 0.91 0.14 0.12 0.22 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0 0 0 0 0 0
Endosome 0.06 0.05 0.09 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0.05 0.05 0.08 0.06
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0.17 0 0.06 0.11 0.15 0.16 0.14 0.13 0.15 0.17 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.18 0.1 0.08 0.06 0.08 0.18 0.11 0.12 0.07 0.1 0.08 0.06 0.06 0 0 0.5 0.37 0.43 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.81 0.79 0.6 0.69 0.66 0.61 0.56 0.51 0.57 0.54 0.42 0.43 0.47 0.34 0.14 0.52 0.66 0.5 0.87 0.89 0.89 0.87 0.81 0.85
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1
Bud 0 0 3 0 3 4 3 9 2 4 5 9 1 2 1 0 0 0 1 3 1 1 4 0
Bud Neck 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0
Cytoplasm 44 60 143 150 185 275 375 371 386 408 403 507 141 299 402 16 15 35 10 5 5 5 3 5
Endoplasmic Reticulum 3 1 1 0 0 3 4 4 1 0 1 1 9 1 3 4 7 8 0 0 2 2 6 3
Endosome 25 10 42 8 22 2 4 2 2 3 1 2 5 4 2 3 2 4 28 6 27 11 29 21
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 1 1
Mitochondria 17 5 81 8 31 74 119 135 100 104 104 140 0 2 0 3 2 2 3 1 7 3 9 6
Nucleus 74 22 39 18 36 118 83 97 54 81 55 54 14 12 4 58 45 69 6 3 3 1 4 4
Nuclear Periphery 1 0 2 2 2 5 13 10 5 6 2 6 0 0 0 0 0 0 2 0 1 1 4 4
Nucleolus 0 0 1 0 2 1 2 2 1 0 1 0 0 0 0 1 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 3 2 0 0 0 0 0 1 0 1 0 0 0 1 1 3 2 1 1 0 1 0
Vac/Vac Membrane 332 173 279 198 318 400 438 431 415 443 288 360 115 137 64 60 80 81 377 215 448 222 299 302
Unique Cell Count 412 219 467 286 479 655 783 838 722 814 682 833 246 401 443 115 122 162 436 243 506 255 370 357
Labelled Cell Count 497 271 595 386 600 882 1041 1062 966 1050 860 1080 286 457 476 146 154 204 436 243 506 255 370 357


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.3 5.7 4.7 5.3 5.6 5.3 4.8 4.8 5.0 4.9 5.0 5.0 5.9 5.2 5.2 7.6 8.5 8.8 7.4 7.1 7.6
Std Deviation (1e-4) 1.1 1.1 1.4 1.5 1.5 1.4 1.6 1.3 1.4 1.4 1.4 1.3 1.2 1.1 1.2 2.0 2.5 3.5 1.7 1.5 1.6
Intensity Change (Log2) – – – 0.15 0.25 0.17 0.03 0.01 0.09 0.05 0.09 0.07 0.33 0.14 0.14 0.67 0.84 0.89 0.65 0.59 0.68

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 6.0 2.6 3.9 6.0 4.8 7.7 6.8 9.5 10.5 6.9 12.9 18.5 -3.6 -4.1 -2.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome -3.3 -2.7 -7.4 0 0 -7.8 -8.1 -7.8 -8.4 -3.6 -5.2 -6.0 -2.3 -2.8 -2.7
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -6.0 -5.2 -2.9 0 0 -1.6 -2.2 -0.9 -0.2 -6.9 -8.4 -9.2 -4.0 -4.4 -5.2
Nucleus -1.0 -0.5 4.6 1.3 1.8 -0.5 0.9 -0.2 -1.3 -1.3 -3.3 -5.3 10.8 8.0 10.0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 2.6 2.1 0.4 -1.3 -2.9 -0.8 -1.8 -5.8 -5.7 -3.3 -7.5 -14.1 -1.5 1.2 -2.2

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.5835 3.2603 3.0512 2.5571 2.3751 3.1471 4.2857 6.4383 5.6198 5.3869 5.3809 5.9008 2.2998 5.0165 3.7655 3.8261 3.8496 4.0488
Actin 0.0043 0 0.0003 0 0.0001 0.0001 0.0058 0 0.0005 0 0 0.0003 0.0082 0 0.0033 0 0 0
Bud 0.0006 0.0005 0.0004 0.0002 0.0014 0.0007 0.0006 0.0002 0.0004 0.0004 0.0002 0.0003 0.0002 0.0002 0.0002 0.0002 0.0002 0.0002
Bud Neck 0.0031 0.0013 0.0022 0.0004 0.0014 0.0013 0.001 0.0008 0.0012 0.0008 0.0008 0.0016 0.0008 0.0006 0.001 0.001 0.0012 0.0011
Bud Periphery 0.0015 0.0013 0.0009 0.0007 0.0053 0.0015 0.0018 0.001 0.0016 0.0013 0.0006 0.0019 0.0008 0.0006 0.0007 0.0006 0.0006 0.0012
Bud Site 0.0082 0.0012 0.0021 0.0003 0.0011 0.0006 0.0012 0.0005 0.001 0.0005 0.0003 0.0006 0.0005 0.0005 0.0004 0.0004 0.0009 0.0007
Cell Periphery 0.0024 0.0032 0.0039 0.0021 0.0036 0.0039 0.0043 0.0073 0.005 0.0038 0.0044 0.0071 0.0033 0.0037 0.0032 0.004 0.0052 0.0055
Cytoplasm 0.0041 0.0041 0.0088 0.0011 0.0037 0.0016 0.0035 0.0017 0.0026 0.0005 0.0006 0.0014 0.0021 0.0039 0.0007 0.0004 0.0005 0.0007
Cytoplasmic Foci 0.0315 0.0092 0.0184 0.0073 0.0117 0.0107 0.0124 0.004 0.0069 0.0008 0.0085 0.0041 0.005 0.0025 0.0031 0.0005 0.0025 0.0011
Eisosomes 0.0002 0 0 0 0 0 0.0003 0 0 0 0 0 0.0004 0 0 0 0 0
Endoplasmic Reticulum 0.0043 0.0026 0.0083 0.0005 0.0034 0.0015 0.0025 0.004 0.0037 0.0007 0.0017 0.002 0.0029 0.0029 0.0014 0.0007 0.0007 0.0018
Endosome 0.2543 0.1085 0.2081 0.2043 0.2048 0.0857 0.1549 0.0995 0.1394 0.0815 0.0982 0.1077 0.1907 0.0969 0.1467 0.0592 0.1028 0.0734
Golgi 0.0285 0.0032 0.0087 0.0059 0.008 0.0045 0.0078 0.0043 0.0097 0.0022 0.0045 0.0059 0.0077 0.0036 0.0084 0.0011 0.0044 0.0024
Lipid Particles 0.0598 0.0119 0.0121 0.0055 0.0135 0.0182 0.0224 0.0169 0.0322 0.0062 0.0144 0.0209 0.0351 0.0076 0.0167 0.0029 0.0151 0.0103
Mitochondria 0.0385 0.003 0.0191 0.0032 0.0044 0.0182 0.0133 0.0125 0.0299 0.0147 0.0104 0.0123 0.0227 0.0138 0.0201 0.0012 0.0011 0.0057
None 0.0177 0.0002 0.0009 0.0001 0.0032 0.0007 0.0126 0.0001 0.0032 0 0.0001 0.0013 0.0037 0.0002 0.0001 0 0 0.0001
Nuclear Periphery 0.0112 0.014 0.0109 0.0011 0.0025 0.0031 0.0065 0.0047 0.0045 0.001 0.0024 0.0038 0.0114 0.005 0.0023 0.0015 0.0012 0.0103
Nucleolus 0.0041 0.0035 0.0055 0.0017 0.0055 0.004 0.0048 0.002 0.0052 0.0022 0.002 0.0028 0.0041 0.0021 0.0027 0.0031 0.0042 0.0046
Nucleus 0.0038 0.006 0.0048 0.0017 0.0054 0.004 0.0038 0.0021 0.0029 0.002 0.0016 0.003 0.0031 0.0023 0.0018 0.002 0.0021 0.0042
Peroxisomes 0.0182 0.0008 0.0026 0.0007 0.001 0.0013 0.0046 0.0004 0.007 0.0005 0.0011 0.0017 0.003 0.0002 0.0032 0.0002 0.0008 0.0004
Punctate Nuclear 0.0021 0.0001 0.0003 0.0001 0.0003 0.0001 0.0007 0.0001 0.0008 0 0.0002 0.0018 0.0016 0.0001 0.0001 0 0 0.0007
Vacuole 0.3533 0.6467 0.5191 0.5916 0.6059 0.6738 0.5222 0.6343 0.5546 0.6793 0.6621 0.624 0.4866 0.6147 0.5461 0.6981 0.6828 0.6528
Vacuole Periphery 0.1485 0.1787 0.1627 0.1718 0.1139 0.1646 0.2129 0.2037 0.1878 0.2016 0.1861 0.1955 0.2061 0.2384 0.2378 0.2232 0.1737 0.2228

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 182.5005 141.0301 126.9428 119.9302 144.0295 160.4742 146.8142 131.5501 118.7571 163.5304
Translational Efficiency 1.0532 1.1722 0.9706 1.1762 1.1865 1.0969 1.0876 1.063 0.9064 0.9833

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1480 1596 118 992 1920 124 136 1064 3400 1720 254 2056

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 669.45 842.70 922.14 907.98 748.92 806.90 963.42 959.22 714.33 840.12 944.24 934.50
Standard Deviation 78.38 122.99 100.01 144.88 100.19 95.04 99.37 141.04 99.47 121.54 101.77 145.18
Intensity Change Log 2 — 0.332043 0.462009 0.439684 — 0.107578 0.363353 0.357050 — 0.217882 0.410759 0.396643

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000046 0.000045 0.001069 0.001669 0.000053 0.000083 0.000396 0.001950 0.000050 0.000048 0.000709 0.001815
Bud Neck 0.029285 0.011398 0.006530 0.020374 0.014658 0.022558 0.016385 0.020572 0.021025 0.012202 0.011807 0.020477
Bud Site 0.011077 0.010434 0.019528 0.053053 0.007908 0.005554 0.008377 0.050295 0.009287 0.010082 0.013557 0.051626
Cell Periphery 0.000323 0.000374 0.000140 0.000142 0.000228 0.000976 0.000109 0.000159 0.000269 0.000417 0.000124 0.000151
Cytoplasm 0.072855 0.024119 0.092772 0.099903 0.053399 0.017897 0.053581 0.105555 0.061868 0.023670 0.071788 0.102828
Cytoplasmic Foci 0.064795 0.016519 0.139693 0.082409 0.033112 0.026158 0.047793 0.119265 0.046903 0.017214 0.090487 0.101482
Eisosomes 0.000074 0.000016 0.000069 0.000024 0.000019 0.000067 0.000070 0.000033 0.000043 0.000019 0.000069 0.000029
Endoplasmic Reticulum 0.004929 0.003206 0.008376 0.001114 0.001677 0.002087 0.004913 0.001562 0.003092 0.003125 0.006522 0.001346
Endosome 0.219004 0.067061 0.239041 0.202207 0.091776 0.069290 0.279183 0.280627 0.147158 0.067222 0.260534 0.242790
Golgi 0.002819 0.002208 0.003199 0.010564 0.001898 0.002115 0.001109 0.009671 0.002299 0.002201 0.002080 0.010102
Lipid Particles 0.009636 0.001087 0.019338 0.002690 0.001692 0.013026 0.010708 0.003665 0.005150 0.001947 0.014717 0.003195
Mitochondria 0.004486 0.001294 0.000408 0.005391 0.002154 0.018306 0.000358 0.003571 0.003169 0.002521 0.000381 0.004449
Mitotic Spindle 0.000232 0.001086 0.013390 0.020831 0.000347 0.000297 0.018748 0.016732 0.000297 0.001029 0.016259 0.018710
None 0.000381 0.000199 0.000478 0.000262 0.000167 0.000098 0.000262 0.000258 0.000260 0.000192 0.000362 0.000260
Nuclear Periphery 0.000729 0.000180 0.001776 0.000396 0.000240 0.000993 0.002870 0.000454 0.000453 0.000239 0.002362 0.000426
Nuclear Periphery Foci 0.000227 0.000174 0.018597 0.001396 0.000113 0.000334 0.015817 0.001930 0.000163 0.000186 0.017109 0.001672
Nucleolus 0.001045 0.000652 0.002705 0.001136 0.000513 0.002658 0.010596 0.000953 0.000745 0.000796 0.006930 0.001041
Nucleus 0.018750 0.003796 0.034067 0.006559 0.006701 0.011499 0.039258 0.005993 0.011946 0.004351 0.036846 0.006266
Peroxisomes 0.003126 0.000948 0.016902 0.014787 0.001288 0.005764 0.015503 0.026301 0.002088 0.001295 0.016153 0.020746
Vacuole 0.537312 0.811832 0.376977 0.465264 0.762193 0.784830 0.470036 0.344707 0.664304 0.809885 0.426804 0.402874
Vacuole Periphery 0.018868 0.043374 0.004945 0.009828 0.019866 0.015408 0.003928 0.005747 0.019432 0.041358 0.004401 0.007716

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.10 -2.06 -2.46 -2.46 -0.50 -0.86 -3.31 -3.75 -3.68 -2.77 -0.00 -2.88 -4.31 -4.31 -2.00
Bud Neck 8.29 10.45 3.62 -5.30 -8.05 -1.18 -0.21 -2.76 0.38 -1.36 6.30 4.88 0.57 -5.60 -4.41
Bud Site 0.35 -0.94 -9.82 -10.42 -3.90 0.84 -0.27 -11.56 -9.42 -10.81 -0.77 -1.01 -15.18 -14.54 -8.31
Cell Periphery -1.23 5.25 5.28 5.64 0.37 -3.25 3.67 2.60 3.68 -0.67 -3.69 6.10 5.28 7.20 -0.17
Cytoplasm 11.82 -1.92 -7.97 -16.16 -1.39 6.07 -1.00 -11.29 -14.14 -4.34 12.69 -2.13 -13.86 -22.25 -3.99
Cytoplasmic Foci 15.56 -5.13 -2.55 -15.38 4.24 0.74 -2.36 -16.38 -8.83 -6.98 13.48 -5.41 -14.05 -24.25 -0.18
Eisosomes 10.67 -0.10 8.88 -3.32 6.26 -2.64 -6.58 -4.70 1.85 4.82 7.47 -5.20 4.71 -3.59 7.67
Endoplasmic Reticulum 2.93 -1.17 7.13 5.22 2.56 -1.24 -4.16 0.82 1.69 4.32 -0.10 -2.68 6.17 5.23 4.01
Endosome 22.02 0.23 6.05 -12.90 2.20 1.66 -6.26 -15.44 -10.11 0.71 17.78 -4.89 -7.48 -21.20 1.99
Golgi 0.99 0.03 -3.12 -3.51 -3.04 -0.24 2.42 -4.31 -3.44 -5.15 0.19 1.21 -5.21 -5.09 -5.62
Lipid Particles 9.93 -2.33 7.73 -6.75 4.07 -1.57 -4.17 -5.31 1.25 3.14 4.67 -4.34 3.65 -2.59 5.12
Mitochondria 3.80 4.89 0.20 -2.46 -3.22 -1.66 3.36 -0.76 1.59 -3.38 0.76 5.90 -0.39 -0.98 -4.54
Mitotic Spindle -1.45 -2.33 -7.36 -6.99 -1.60 0.18 -1.82 -7.29 -7.31 -0.34 -1.33 -2.72 -10.34 -9.70 -1.13
None 1.77 -0.85 0.46 -1.02 1.09 1.06 -1.50 -1.62 -2.38 0.16 0.99 -1.56 -0.75 -1.54 0.99
Nuclear Periphery 5.11 -2.75 0.22 -6.18 2.81 -1.59 -4.11 -2.99 0.72 3.60 2.52 -4.97 -2.34 -5.76 4.56
Nuclear Periphery Foci 1.25 -4.74 -5.66 -5.80 4.33 -3.06 -4.34 -5.01 -4.58 3.66 -0.65 -6.42 -7.13 -7.03 5.64
Nucleolus 2.09 -1.59 -1.41 -3.14 1.41 -1.30 -2.60 -2.98 0.94 2.43 -0.42 -3.02 -3.30 -1.92 2.78
Nucleus 8.53 -2.43 4.11 -6.24 3.37 -1.70 -4.32 -2.43 0.69 4.05 7.85 -4.98 1.74 -7.01 5.26
Peroxisomes 5.35 -2.91 -6.09 -7.73 0.80 -2.34 -3.04 -11.28 -5.99 -1.89 2.71 -4.23 -12.71 -13.32 -0.82
Vacuole -27.44 5.69 4.15 29.13 -3.66 -0.77 10.65 32.86 13.34 3.10 -18.85 11.91 26.11 42.38 -0.15
Vacuole Periphery -11.75 9.28 8.83 17.28 -2.24 1.28 16.67 14.37 3.17 -1.51 -11.70 17.31 16.20 19.18 -2.75
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Alpha-1,2-mannosyltransferase; involved in O- and N-linked protein glycosylation; type II membrane protein; member of the KRE2/MNT1 mannosyltransferase family; relocalizes from vacuole to cytoplasm upon DNA replication stress
Localization
Cell Percentages vacuole (91%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Ktr1

Ktr1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ktr1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available