Standard name
Human Ortholog
Description Transcriptional modulator; involved in regulation of meiosis, silencing, and expression of RNR genes; required for nuclear localization of the ribonucleotide reductase small subunit Rnr2p and Rnr4p; contains WD repeats
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0.08 0.08 0.11 0.06 0.1 0.09 0 0.1 0.06 0.24 0.22 0.26 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0.09 0.2 0.16 0.12 0.18 0.16 0.21 0.19 0 0 0 0.21 0.2 0.14 0 0 0 0 0 0
Nucleus 0.89 0.92 0.92 0.85 0.62 0.42 0.37 0.37 0.35 0.36 0.44 0.49 0.91 0.85 0.82 0.55 0.52 0.51 0.85 0.82 0.68 0.79 0.68 0.37
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.35 0.2 0.15 0.23 0.33 0.57 0.58 0.55 0.51 0.57 0.47 0.44 0.06 0.08 0.14 0.22 0.23 0.2 0.12 0.12 0.24 0.07 0.16 0.36
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Vac/Vac Membrane 0 0 0 0 0.05 0 0 0.05 0.06 0.05 0.05 0 0 0 0 0 0.06 0.05 0 0 0 0.11 0.11 0.12
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 1 1 0 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 10
Bud Site 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Cytoplasm 1 1 2 4 5 6 42 52 45 37 31 46 8 26 22 115 77 59 0 0 1 0 1 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 18 20 7 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 2 5 1 0 0 0 1 0 0 0 1
Golgi 0 0 0 0 0 0 1 5 1 2 0 0 0 0 0 1 2 0 0 0 0 0 0 1
Mitochondria 3 3 5 5 22 60 88 78 74 96 68 93 3 1 2 99 71 32 0 0 0 0 3 3
Nucleus 66 69 195 159 158 127 201 245 148 212 143 245 170 230 295 263 182 117 74 72 153 118 191 98
Nuclear Periphery 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 1 2
Nucleolus 26 15 33 42 84 173 313 368 215 330 153 220 12 21 50 107 80 47 10 10 52 10 44 93
Peroxisomes 0 0 0 0 0 0 0 1 0 0 0 0 1 0 1 0 2 1 0 0 0 0 0 1
SpindlePole 0 0 0 0 0 0 0 2 0 0 0 0 0 1 6 0 0 0 1 0 0 1 2 12
Vac/Vac Membrane 1 1 0 0 12 5 19 35 27 29 16 22 1 3 13 20 21 12 0 1 10 16 29 31
Unique Cell Count 74 75 213 186 254 305 543 665 419 582 323 499 186 271 360 480 351 230 88 88 225 149 281 263
Labelled Cell Count 97 89 235 210 281 371 666 789 513 710 412 628 195 284 395 625 456 275 88 88 225 149 281 263


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 48.4 62.7 50.4 44.6 50.5 57.2 59.8 64.5 67.4 61.1 59.3 64.3 60.5 61.9 65.9 96.5 95.6 99.8 53.5 55.6 62.6
Std Deviation (1e-4) 17.6 20.1 17.8 14.1 16.2 20.4 24.3 28.5 30.4 25.2 25.0 26.2 24.2 29.7 30.6 48.0 48.4 47.1 21.3 23.0 23.7
Intensity Change (Log2) – – – -0.17 0.0 0.18 0.25 0.36 0.42 0.28 0.24 0.35 0.26 0.3 0.39 0.94 0.92 0.99 0.09 0.14 0.31

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700050100WT3HU80HU120HU160050100WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3050100WT1AF100AF140AF180050100
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 3.6 3.6 4.4 3.1 4.1 4.0 0 4.0 3.0 7.5 7.0 7.5
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 2.9 3.5 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 2.9 5.9 5.2 4.1 5.5 5.3 6.2 5.8 0 0 0 6.2 6.0 4.4
Nucleus -1.9 -7.4 -11.5 -13.5 -13.9 -13.4 -13.8 -11.1 -10.7 -0.1 -2.2 -3.2 -9.4 -9.7 -9.4
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 1.8 4.4 9.4 10.5 10.2 8.7 10.3 7.6 7.3 -2.8 -2.7 -0.5 2.1 2.1 1.4
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 3.2 0 2.8 3.4 3.8 3.3 3.3 3.1 0 0 0 3.0 3.6 3.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 37.4471 39.975 36.2402 33.4635 29.7691 38.1988 48.3537 44.0136 35.3774 32.8182 26.7102 38.8294 52.0014 51.4676 42.473 38.1871 43.7437 45.2047
Actin 0.0188 0 0.0103 0.0002 0.0144 0.0003 0.0277 0 0.0107 0.0351 0.023 0.0069 0.001 0 0.0002 0.0003 0 0
Bud 0.0004 0.0001 0.0001 0.0001 0.0003 0.0002 0.0002 0 0.0004 0.0008 0.0005 0.0001 0.0001 0.0001 0 0.0005 0 0.0001
Bud Neck 0.0059 0 0.0005 0.0001 0.0004 0.0003 0.0002 0 0.0008 0.0004 0.0003 0.0002 0.0003 0 0 0.0002 0 0.0002
Bud Periphery 0.0005 0 0.0001 0.0002 0.0006 0.0002 0.0002 0 0.0004 0.0014 0.0004 0.0004 0.0001 0 0 0.0005 0.0001 0.0002
Bud Site 0.0041 0.0006 0.0076 0.0002 0.0007 0.0001 0.0004 0 0.0034 0.0019 0.0007 0.0001 0.0004 0.0002 0.0001 0.0005 0 0
Cell Periphery 0.0007 0.0001 0.0002 0.0004 0.0019 0.0005 0.0002 0.0001 0.0004 0.0001 0.0008 0.0006 0.0003 0 0.0001 0.0008 0.0002 0.0005
Cytoplasm 0.0044 0.0001 0.0003 0.0004 0.0015 0.0001 0.0017 0.0001 0.0004 0.0005 0.002 0.0006 0.0002 0.0001 0.0003 0.0004 0 0.0001
Cytoplasmic Foci 0.0161 0.0016 0.0026 0.0051 0.0061 0.0066 0.0067 0.0044 0.0158 0.0016 0.0134 0.021 0.0106 0.0239 0.0035 0.0255 0 0.0044
Eisosomes 0.0005 0 0.0001 0 0.0002 0 0.0002 0 0.0001 0.0002 0.0002 0.0001 0.0002 0 0 0.0001 0 0
Endoplasmic Reticulum 0.0017 0 0.0003 0.0002 0.0031 0 0.0007 0 0.0002 0.0006 0.0008 0.0003 0.0001 0 0 0 0 0
Endosome 0.0162 0 0.002 0.0006 0.0386 0.0003 0.0045 0 0.0022 0.0051 0.0092 0.0029 0.005 0 0.0002 0.0001 0 0
Golgi 0.0036 0 0.0011 0.0002 0.0077 0.0002 0.0036 0 0.0035 0.0038 0.0112 0.0033 0.0014 0 0.0001 0.0001 0 0
Lipid Particles 0.0122 0.0001 0.0029 0.0053 0.0136 0.0029 0.0017 0.0002 0.0075 0.0016 0.0226 0.012 0.0032 0.0003 0.0033 0.0047 0 0.0004
Mitochondria 0.0097 0.0024 0.0044 0.0063 0.0206 0.0084 0.0135 0.0116 0.0119 0.0064 0.0463 0.0047 0.0071 0.0014 0.0035 0.0069 0.0041 0.0011
None 0.0183 0 0.0006 0.0014 0.0013 0.0001 0.0012 0.0001 0.0006 0.0003 0.0014 0.001 0.0006 0 0.0001 0.0003 0 0.0001
Nuclear Periphery 0.0188 0.0099 0.019 0.0113 0.0115 0.0028 0.0096 0.0026 0.0164 0.0294 0.0587 0.0167 0.0024 0.0051 0.0209 0.0093 0.0007 0.0012
Nucleolus 0.1301 0.0545 0.0484 0.0951 0.3104 0.1873 0.0895 0.0527 0.0638 0.05 0.2646 0.1672 0.109 0.0386 0.0427 0.0639 0.2805 0.1831
Nucleus 0.7061 0.9291 0.8947 0.8388 0.541 0.7803 0.8275 0.892 0.8509 0.8309 0.5019 0.7463 0.8508 0.9018 0.9211 0.8795 0.7122 0.795
Peroxisomes 0.003 0.0001 0.0011 0.0003 0.0018 0.0003 0.0013 0 0.0022 0.0022 0.015 0.0013 0.0011 0.0004 0.0012 0.0007 0 0
Punctate Nuclear 0.0175 0.0004 0.0015 0.0281 0.0018 0.0055 0.0048 0.0346 0.0026 0.0247 0.0149 0.0061 0.004 0.0275 0.0012 0.0013 0.0001 0.0108
Vacuole 0.0044 0.0001 0.0003 0.0015 0.0065 0.0009 0.0006 0.0001 0.0018 0.0007 0.0035 0.0015 0.0006 0.0001 0.0002 0.0014 0.0003 0.0009
Vacuole Periphery 0.0068 0.001 0.0018 0.004 0.016 0.0026 0.0038 0.0014 0.004 0.0024 0.0085 0.0065 0.0015 0.0005 0.0013 0.0032 0.0016 0.0019

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 177.1829 111.0987 167.6652 233.4561 267.2871 178.7633 136.2402 176.2218 251.2244 285.0979
Translational Efficiency 1.3441 1.5851 1.2693 1.361 1.23 1.1809 1.4175 1.3182 1.3612 1.3066

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
193 189 1551 483 1391 1859 160 1222 1584 2048 1711 1705

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 3969.33 4041.01 2575.39 2181.95 3758.43 3074.37 3582.64 2515.89 3784.13 3163.58 2669.58 2421.29
Standard Deviation 1563.85 1066.42 789.08 897.14 1061.71 907.71 946.54 760.33 1136.93 964.94 856.86 815.46
Intensity Change Log 2 — 0.025820 -0.624105 -0.863277 — -0.289839 -0.069107 -0.579061 — -0.119109 -0.327581 -0.718053

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000628 0.001077 0.001195 0.001570 0.001035 0.001061 0.001655 0.002044 0.000985 0.001062 0.001238 0.001910
Bud Neck 0.003399 0.004773 0.008884 0.015144 0.001774 0.002240 0.008969 0.020900 0.001972 0.002474 0.008892 0.019269
Bud Site 0.004066 0.000936 0.000711 0.002962 0.000400 0.000348 0.000682 0.001869 0.000847 0.000403 0.000708 0.002179
Cell Periphery 0.000102 0.000045 0.000053 0.000168 0.000057 0.000074 0.000031 0.000120 0.000062 0.000072 0.000051 0.000134
Cytoplasm 0.001512 0.000182 0.000726 0.004399 0.000107 0.000147 0.000060 0.001466 0.000278 0.000150 0.000664 0.002297
Cytoplasmic Foci 0.057663 0.009434 0.002063 0.003678 0.008787 0.001643 0.000636 0.002778 0.014742 0.002362 0.001930 0.003033
Eisosomes 0.000375 0.000180 0.000066 0.000051 0.000373 0.000291 0.000165 0.000044 0.000373 0.000281 0.000076 0.000046
Endoplasmic Reticulum 0.000435 0.000111 0.000386 0.001313 0.000127 0.000211 0.000281 0.000837 0.000165 0.000202 0.000376 0.000972
Endosome 0.000730 0.000107 0.000027 0.001045 0.000008 0.000006 0.000014 0.001053 0.000096 0.000016 0.000026 0.001051
Golgi 0.000709 0.000658 0.000091 0.000451 0.000036 0.000020 0.000100 0.000817 0.000118 0.000079 0.000091 0.000714
Lipid Particles 0.003439 0.000158 0.000013 0.000466 0.000046 0.000003 0.000020 0.000093 0.000459 0.000018 0.000013 0.000199
Mitochondria 0.002084 0.001948 0.003074 0.005475 0.001944 0.001790 0.004872 0.008825 0.001961 0.001804 0.003242 0.007876
Mitotic Spindle 0.020283 0.000161 0.000559 0.025323 0.000662 0.000148 0.001433 0.029101 0.003053 0.000149 0.000641 0.028031
None 0.003368 0.001044 0.001042 0.004462 0.000783 0.000706 0.000606 0.001921 0.001098 0.000737 0.001001 0.002641
Nuclear Periphery 0.000155 0.000067 0.001764 0.007248 0.000048 0.000154 0.000249 0.019894 0.000061 0.000146 0.001623 0.016311
Nuclear Periphery Foci 0.004031 0.000028 0.000344 0.002350 0.000027 0.000044 0.000053 0.004663 0.000515 0.000042 0.000317 0.004008
Nucleolus 0.487621 0.122919 0.189285 0.121274 0.095963 0.070350 0.205448 0.252287 0.143684 0.075201 0.190796 0.215173
Nucleus 0.145116 0.832686 0.781156 0.794029 0.860998 0.912283 0.754252 0.639715 0.773773 0.904938 0.778640 0.683430
Peroxisomes 0.262536 0.020945 0.005347 0.005870 0.025013 0.006317 0.019304 0.008019 0.053954 0.007667 0.006652 0.007410
Vacuole 0.001074 0.000472 0.000675 0.001893 0.000575 0.000636 0.000520 0.001612 0.000636 0.000621 0.000661 0.001692
Vacuole Periphery 0.000674 0.002069 0.002538 0.000830 0.001236 0.001529 0.000652 0.001941 0.001167 0.001579 0.002362 0.001626

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.02 -4.99 -8.12 -3.56 -5.77 -0.46 -4.51 -10.69 -11.59 -2.09 -1.18 -4.24 -12.33 -12.68 -10.20
Bud Neck -0.45 -5.72 -8.39 -6.25 -6.17 -2.34 -8.21 -15.77 -15.48 -10.79 -1.63 -15.55 -18.23 -17.76 -12.63
Bud Site 1.51 1.57 0.02 -4.64 -5.43 0.23 -3.35 -8.69 -8.56 -7.78 1.56 0.49 -6.74 -10.19 -9.05
Cell Periphery 1.39 1.28 -0.24 -7.05 -7.50 -0.90 1.20 -5.06 -4.33 -7.04 0.01 0.88 -5.00 -5.84 -8.36
Cytoplasm 1.61 1.17 -1.24 -5.80 -4.67 -0.56 0.61 -6.97 -6.85 -7.20 1.38 -0.90 -6.58 -8.78 -4.83
Cytoplasmic Foci 4.79 6.63 6.42 0.94 -0.83 4.30 5.04 2.58 -2.40 -3.70 6.51 6.57 5.57 -1.62 -1.74
Eisosomes 4.44 8.34 8.67 5.25 3.04 1.94 6.47 11.01 8.13 9.71 2.43 11.22 12.29 8.48 9.16
Endoplasmic Reticulum 1.30 0.26 -2.96 -6.10 -4.87 -5.18 -3.87 -9.22 -8.19 -5.88 -0.84 -5.28 -9.51 -9.77 -7.46
Endosome 1.43 1.52 0.30 -1.87 -2.07 0.48 -1.62 -1.95 -1.96 -1.93 1.47 1.25 -2.09 -2.58 -2.52
Golgi 0.25 2.87 1.10 0.20 -3.97 2.59 -3.13 -3.53 -3.60 -3.19 0.83 0.58 -3.67 -3.84 -3.84
Lipid Particles 1.49 1.56 1.29 -1.57 -2.52 1.56 0.59 -3.59 -5.89 -4.91 1.63 1.61 0.55 -4.08 -4.09
Mitochondria 0.44 -2.62 -6.03 -7.65 -5.30 0.69 -6.03 -13.68 -14.73 -5.54 0.81 -6.44 -15.00 -16.53 -11.74
Mitotic Spindle 2.83 2.74 -0.97 -5.59 -5.46 1.29 -0.57 -8.73 -8.94 -8.15 3.07 2.28 -8.99 -10.55 -10.26
None 1.06 1.06 -0.25 -4.56 -5.35 0.97 3.04 -6.48 -6.69 -7.23 1.26 0.34 -4.44 -8.71 -6.73
Nuclear Periphery 2.44 -2.75 -3.13 -3.19 -2.23 -2.96 -3.15 -7.03 -6.98 -6.94 -2.53 -2.97 -7.66 -7.61 -6.47
Nuclear Periphery Foci 1.66 1.55 0.96 -2.91 -2.41 -0.82 -1.27 -6.28 -6.26 -6.24 1.62 0.81 -4.50 -6.89 -6.14
Nucleolus 15.41 14.84 17.16 0.13 5.85 4.43 -4.63 -15.62 -19.51 -1.92 10.20 -5.57 -7.35 -17.86 -1.86
Nucleus -28.31 -36.15 -29.86 2.71 0.56 -6.79 3.99 19.35 26.60 5.18 -14.04 -0.56 8.48 25.74 10.19
Peroxisomes 15.81 17.85 17.88 3.10 0.59 8.12 1.75 8.00 -1.02 3.86 13.81 14.32 14.52 0.97 0.24
Vacuole 2.21 1.38 -2.48 -3.53 -3.20 -0.59 -0.61 -4.20 -4.12 -3.96 0.75 -0.78 -5.19 -5.37 -4.75
Vacuole Periphery -1.25 -3.61 -0.40 1.20 3.48 -0.63 1.39 -0.83 -0.32 -3.45 -0.96 -1.98 -0.52 0.68 1.92
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Transcriptional modulator; involved in regulation of meiosis, silencing, and expression of RNR genes; required for nuclear localization of the ribonucleotide reductase small subunit Rnr2p and Rnr4p; contains WD repeats
Localization
Cell Percentages nucleus (76%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-1

Wtm1

Wtm1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Wtm1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available