Standard name
Description RNA-binding protein that may be involved in translational regulation; binds specific categories of mRNAs, including those that contain upstream open reading frames (uORFs) and internal ribosome entry sites (IRES); interacts genetically with chromatin remodelers and splicing factors, linking chromatin state, splicing and as a result mRNA maturation

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0.05 0 0 0 0.05 0.06 0.06 0.08 0.07 0.05 0 0.08 0.14 0.08 0 0 0 0 0 0
Cytoplasm 1.0 0.97 0.94 0.95 0.86 0.8 0.69 0.68 0.66 0.67 0.68 0.65 0.97 0.99 0.96 0.95 0.91 0.95 0.93 0.92 0.85 0.87 0.88 0.91
Endoplasmic Reticulum 0 0 0.05 0 0.06 0.06 0.16 0.16 0.1 0.12 0.09 0.1 0 0 0 0 0 0 0 0 0.12 0.08 0.06 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.18 0.13 0.12 0.2 0.19 0.25 0.18 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.05 0 0.06 0.08 0.1 0.07 0 0.1 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 1 0 4 1 7 6 8 12 14 9 0 0 0 0 2 0 0 1 2 0 0 0
Bud 0 0 1 0 1 1 3 8 4 2 6 3 2 2 0 1 0 0 0 2 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 2 18 15 7 24 14 18 32 32 46 40 51 18 17 8 17 27 18 0 0 2 0 0 1
Cytoplasm 120 742 420 251 441 415 495 551 446 506 420 432 235 337 264 197 177 217 131 697 382 167 328 259
Endoplasmic Reticulum 1 25 23 8 29 32 113 129 69 90 54 69 4 6 6 5 7 7 3 27 52 14 20 11
Endosome 0 1 1 0 1 0 1 1 1 1 0 1 1 0 1 0 2 1 2 4 0 0 4 0
Golgi 0 2 1 1 0 0 2 2 0 1 1 2 1 0 0 0 1 0 0 2 1 0 3 0
Mitochondria 0 0 0 4 14 96 94 98 136 139 158 121 0 0 0 1 1 1 0 2 2 1 3 2
Nucleus 0 2 1 1 2 1 5 2 2 3 4 0 0 0 1 4 1 1 0 1 0 0 0 0
Nuclear Periphery 0 0 0 0 0 6 8 3 0 3 2 7 0 0 0 0 0 0 0 1 0 0 2 0
Nucleolus 0 0 0 0 1 1 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 1 5 5 26 22 46 63 69 54 26 66 2 0 4 4 7 6 1 6 1 4 6 4
Unique Cell Count 120 764 446 264 511 520 719 808 673 751 622 664 243 342 276 208 194 228 141 755 451 192 374 287
Labelled Cell Count 123 792 468 277 543 589 792 895 767 857 725 762 263 362 284 229 225 252 141 755 451 192 374 287


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 13.3 13.8 12.5 11.9 11.0 9.9 9.9 10.4 10.0 10.0 9.8 10.2 13.5 13.0 13.0 11.8 11.9 12.0 11.1 11.4 11.4
Std Deviation (1e-4) 1.5 1.9 2.0 2.0 1.8 1.9 1.9 1.9 2.2 2.1 2.1 2.1 1.5 1.3 1.6 2.2 2.4 2.1 1.2 1.3 1.3
Intensity Change (Log2) -0.07 -0.17 -0.34 -0.33 -0.26 -0.32 -0.32 -0.35 -0.3 0.12 0.06 0.07 -0.08 -0.07 -0.06 -0.16 -0.13 -0.12


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 2.8 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -0.5 1.0 -0.6 -0.9 0.5 1.1 2.1 2.2 3.0 2.4 1.1 -0.3 2.7 5.0 2.6
Cytoplasm 0.5 -4.0 -6.5 -10.2 -10.5 -10.9 -10.7 -10.5 -11.3 1.5 3.1 0.9 0.3 -1.4 0.5
Endoplasmic Reticulum -1.3 0.4 0.7 5.5 5.6 3.0 3.9 2.2 3.1 -2.3 -2.5 -2.0 -1.6 -0.9 -1.2
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 3.5 9.6 8.0 7.7 10.1 9.7 11.5 9.6 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 3.5 2.9 4.3 5.0 6.0 4.7 2.9 5.9 0 0 0 0 0 0


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mrn1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available